ANABANAPTYSBIO, INC
- Market cap
- $1.46B
- as of 2026-10-23
- Latest close
- $48.73
- as of 2026-10-23
- Sector
- Healthcare
- as of 2026-10-24
- Industry
- Biotechnology
- as of 2026-10-24
Cluster
No cluster in the last 90 days under the default rule (14d · ≥2 insiders · all roles).
Form 4 historysince 2023-11-27
Dashed line = amended filing (Form 4/A)
| Insider | Traded | Filed | Type | Shares | Price | Value | Owned after | 10b5-1 plan | Filing |
|---|---|---|---|---|---|---|---|---|---|
| Renton Hollings | Oct 1 | Oct 2 | M | 5,000 | $18.03 | $90,150 | 15,995 | Yes | Form 4 |
| Renton Hollings | Oct 1 | Oct 2 | S | 5,000 | $49.87 | Sale −$249,372 | 10,995 | Yes | Form 4 |
| Renton Hollings | Oct 1 | Oct 2 | M · derivative | 5,000 | $18.03 | $90,150 | 10,000 | Yes | Form 4 |
| Orwin John A | Sep 15 | Sep 17 | M | 1,300 | $0.00 | $0 | 17,995 | No | Form 4 |
| Orwin John A | Sep 15 | Sep 17 | M · derivative | 1,300 | $0.00 | $0 | not reported | No | Form 4 |
| Faga DanielPresident, CEO | Mar 12 | Aug 7 | A · derivative | 53,334 | $0.00 | $0 | 53,334 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Mar 12 | Aug 7 | A · derivative | 16,667 | $0.00 | $0 | 16,667 | No | Form 4 |
| Renton Hollings | Jun 15 | Jun 17 | M | 6,030 | $0.00 | $0 | 10,995 | No | Form 4 |
| Renton Hollings | Jun 15 | Jun 17 | M · derivative | 6,030 | $0.00 | $0 | not reported | No | Form 4 |
| Orwin John A | Jun 15 | Jun 17 | M | 6,030 | $0.00 | $0 | 16,695 | No | Form 4 |
| Orwin John A | Jun 15 | Jun 17 | M · derivative | 6,030 | $0.00 | $0 | not reported | No | Form 4 |
| Schmid John P. | Jun 15 | Jun 17 | M | 6,030 | $0.00 | $0 | 37,652 | No | Form 4 |
| Schmid John P. | Jun 15 | Jun 17 | M · derivative | 6,030 | $0.00 | $0 | not reported | No | Form 4 |
| Hughes Owen | May 11 | May 13 | A · derivative | 11,250 | $0.00 | $0 | 11,250 | No | Form 4 |
| Murphy Christopher M.Chief Financial Officer | May 11 | May 13 | A · derivative | 25,765 | $0.00 | $0 | 25,765 | No | Form 4 |
| Gray Susannah | Apr 27 | Apr 29 | A · derivative | 11,250 | $0.00 | $0 | 11,250 | No | Form 4 |
| Faga DanielPresident, CEO | Apr 20 | Apr 234/A | D · derivative | 11,000 | $31.12 | $342,320 | 11,000 | No | Form 4/A |
| Renton Hollings | Apr 20 | Apr 22 | D · derivative | 15,000 | $24.60 | $369,000 | 15,000 | No | Form 4 |
| Renton Hollings | Apr 20 | Apr 22 | A · derivative | 15,000 | $18.03 | $270,450 | 15,000 | No | Form 4 |
| Renton Hollings | Apr 20 | Apr 22 | D · derivative | 6,000 | $104.81 | $628,860 | 6,000 | No | Form 4 |
| Renton Hollings | Apr 20 | Apr 22 | A · derivative | 6,000 | $76.79 | $460,740 | 6,000 | No | Form 4 |
| Renton Hollings | Apr 20 | Apr 22 | D · derivative | 6,000 | $68.88 | $413,280 | 6,000 | No | Form 4 |
| Renton Hollings | Apr 20 | Apr 22 | A · derivative | 6,000 | $50.47 | $302,820 | 6,000 | No | Form 4 |
| Renton Hollings | Apr 20 | Apr 22 | D · derivative | 11,000 | $16.56 | $182,160 | 11,000 | No | Form 4 |
| Renton Hollings | Apr 20 | Apr 22 | A · derivative | 11,000 | $12.14 | $133,540 | 11,000 | No | Form 4 |
| Renton Hollings | Apr 20 | Apr 22 | D · derivative | 11,000 | $29.70 | $326,700 | 11,000 | No | Form 4 |
| Renton Hollings | Apr 20 | Apr 22 | A · derivative | 11,000 | $21.76 | $239,360 | 11,000 | No | Form 4 |
| Renton Hollings | Apr 20 | Apr 22 | D · derivative | 9,200 | $30.44 | $280,048 | 9,200 | No | Form 4 |
| Renton Hollings | Apr 20 | Apr 22 | A · derivative | 9,200 | $22.13 | $203,596 | 9,200 | No | Form 4 |
| Renton Hollings | Apr 20 | Apr 22 | D · derivative | 10,600 | $23.23 | $246,238 | 10,600 | No | Form 4 |
| Renton Hollings | Apr 20 | Apr 22 | A · derivative | 10,600 | $17.02 | $180,412 | 10,600 | No | Form 4 |
| Renton Hollings | Apr 20 | Apr 22 | D · derivative | 16,510 | $21.19 | $349,847 | 16,510 | No | Form 4 |
| Renton Hollings | Apr 20 | Apr 22 | A · derivative | 16,510 | $15.53 | $256,400 | 16,510 | No | Form 4 |
| Renton Hollings | Apr 20 | Apr 22 | D · derivative | 16,510 | $14.83 | $244,843 | 16,510 | No | Form 4 |
| Renton Hollings | Apr 20 | Apr 22 | A · derivative | 16,510 | $10.87 | $179,464 | 16,510 | No | Form 4 |
| Renton Hollings | Apr 20 | Apr 22 | D · derivative | 5,500 | $43.91 | $241,505 | 5,500 | No | Form 4 |
| Renton Hollings | Apr 20 | Apr 22 | A · derivative | 5,500 | $32.17 | $176,935 | 5,500 | No | Form 4 |
| Orwin John A | Apr 20 | Apr 22 | D · derivative | 3,311 | $19.50 | $64,565 | 3,311 | No | Form 4 |
| Orwin John A | Apr 20 | Apr 22 | A · derivative | 3,311 | $14.29 | $47,314 | 3,311 | No | Form 4 |
| Orwin John A | Apr 20 | Apr 22 | D · derivative | 10,600 | $19.50 | $206,700 | 10,600 | No | Form 4 |
| Orwin John A | Apr 20 | Apr 22 | A · derivative | 10,600 | $14.29 | $151,474 | 10,600 | No | Form 4 |
| Orwin John A | Apr 20 | Apr 22 | D · derivative | 16,510 | $21.19 | $349,847 | 16,510 | No | Form 4 |
| Orwin John A | Apr 20 | Apr 22 | A · derivative | 16,510 | $15.53 | $256,400 | 16,510 | No | Form 4 |
| Orwin John A | Apr 20 | Apr 22 | D · derivative | 16,510 | $14.83 | $244,843 | 16,510 | No | Form 4 |
| Orwin John A | Apr 20 | Apr 22 | A · derivative | 16,510 | $10.87 | $179,464 | 16,510 | No | Form 4 |
| Orwin John A | Apr 20 | Apr 22 | D · derivative | 8,250 | $43.91 | $362,258 | 8,250 | No | Form 4 |
| Orwin John A | Apr 20 | Apr 22 | A · derivative | 8,250 | $32.17 | $265,403 | 8,250 | No | Form 4 |
| Schmid John P. | Apr 20 | Apr 22 | D · derivative | 15,000 | $24.60 | $369,000 | 15,000 | No | Form 4 |
| Schmid John P. | Apr 20 | Apr 22 | A · derivative | 15,000 | $18.03 | $270,450 | 15,000 | No | Form 4 |
| Schmid John P. | Apr 20 | Apr 22 | D · derivative | 6,000 | $104.81 | $628,860 | 6,000 | No | Form 4 |
| Schmid John P. | Apr 20 | Apr 22 | A · derivative | 6,000 | $76.79 | $460,740 | 6,000 | No | Form 4 |
| Schmid John P. | Apr 20 | Apr 22 | D · derivative | 6,000 | $68.88 | $413,280 | 6,000 | No | Form 4 |
| Schmid John P. | Apr 20 | Apr 22 | A · derivative | 6,000 | $50.47 | $302,820 | 6,000 | No | Form 4 |
| Schmid John P. | Apr 20 | Apr 22 | D · derivative | 11,000 | $16.56 | $182,160 | 11,000 | No | Form 4 |
| Schmid John P. | Apr 20 | Apr 22 | A · derivative | 11,000 | $12.14 | $133,540 | 11,000 | No | Form 4 |
| Schmid John P. | Apr 20 | Apr 22 | D · derivative | 11,000 | $29.70 | $326,700 | 11,000 | No | Form 4 |
| Schmid John P. | Apr 20 | Apr 22 | A · derivative | 11,000 | $21.76 | $239,360 | 11,000 | No | Form 4 |
| Schmid John P. | Apr 20 | Apr 22 | D · derivative | 9,200 | $30.44 | $280,048 | 9,200 | No | Form 4 |
| Schmid John P. | Apr 20 | Apr 22 | A · derivative | 9,200 | $22.13 | $203,596 | 9,200 | No | Form 4 |
| Schmid John P. | Apr 20 | Apr 22 | D · derivative | 10,600 | $23.23 | $246,238 | 10,600 | No | Form 4 |
| Schmid John P. | Apr 20 | Apr 22 | A · derivative | 10,600 | $17.02 | $180,412 | 10,600 | No | Form 4 |
| Schmid John P. | Apr 20 | Apr 22 | D · derivative | 16,510 | $21.19 | $349,847 | 16,510 | No | Form 4 |
| Schmid John P. | Apr 20 | Apr 22 | A · derivative | 16,510 | $15.53 | $256,400 | 16,510 | No | Form 4 |
| Schmid John P. | Apr 20 | Apr 22 | D · derivative | 16,510 | $14.83 | $244,843 | 16,510 | No | Form 4 |
| Schmid John P. | Apr 20 | Apr 22 | A · derivative | 16,510 | $10.87 | $179,464 | 16,510 | No | Form 4 |
| Schmid John P. | Apr 20 | Apr 22 | D · derivative | 5,500 | $43.91 | $241,505 | 5,500 | No | Form 4 |
| Schmid John P. | Apr 20 | Apr 22 | A · derivative | 5,500 | $32.17 | $176,935 | 5,500 | No | Form 4 |
| Schmid John P. | Mar 30 | Apr 1 | S | 12,596 | $55.71 | Sale −$701,723 | 39,671 | No | Form 4 |
| Schmid John P. | Mar 30 | Apr 1 | S | 7,527 | $56.70 | Sale −$426,781 | 32,144 | No | Form 4 |
| Schmid John P. | Mar 30 | Apr 1 | S | 522 | $57.40 | Sale −$29,963 | 31,622 | No | Form 4 |
| Faga DanielPresident, CEO | Mar 27 | Mar 27 | S | 510 | $56.61 | Sale −$28,871 | 513,134 | No | Form 4 |
| Faga DanielPresident, CEO | Mar 27 | Mar 27 | S | 2,570 | $57.91 | Sale −$148,829 | 510,564 | No | Form 4 |
| Faga DanielPresident, CEO | Mar 27 | Mar 27 | S | 3,662 | $58.62 | Sale −$214,666 | 506,902 | No | Form 4 |
| Faga DanielPresident, CEO | Mar 27 | Mar 27 | S | 490 | $59.62 | Sale −$29,214 | 506,412 | No | Form 4 |
| Faga DanielPresident, CEO | Mar 27 | Mar 27 | S | 550 | $60.63 | Sale −$33,347 | 505,862 | No | Form 4 |
| Faga DanielPresident, CEO | Mar 27 | Mar 27 | S | 1,012 | $62.15 | Sale −$62,896 | 504,850 | No | Form 4 |
| Faga DanielPresident, CEO | Mar 27 | Mar 27 | S | 2,592 | $63.35 | Sale −$164,203 | 502,258 | No | Form 4 |
| Faga DanielPresident, CEO | Mar 27 | Mar 27 | S | 3,155 | $64.19 | Sale −$202,519 | 499,103 | No | Form 4 |
| Faga DanielPresident, CEO | Mar 27 | Mar 27 | S | 3,038 | $65.20 | Sale −$198,078 | 496,065 | No | Form 4 |
| Faga DanielPresident, CEO | Mar 27 | Mar 27 | S | 100 | $65.99 | Sale −$6,599 | 495,965 | No | Form 4 |
| Faga DanielPresident, CEO | Mar 25 | Mar 27 | A | 34,300 | not reported | not reported | 513,644 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Feb 11 | Feb 13 | M | 10,000 | $29.70 | $297,000 | 22,835 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Feb 11 | Feb 13 | S | 10,000 | $54.00 | Sale −$540,000 | 12,835 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Feb 11 | Feb 13 | M · derivative | 10,000 | $29.70 | $297,000 | 35,000 | Yes | Form 4 |
| Marquet Magda | Jan 15 | Jan 16 | M | 11,000 | $26.11 | $287,210 | 20,930 | No | Form 4 |
| Marquet Magda | Jan 15 | Jan 16 | S | 9,290 | $48.12 | Sale −$447,035 | 11,640 | No | Form 4 |
| Marquet Magda | Jan 15 | Jan 16 | S | 1,710 | $48.85 | Sale −$83,534 | 9,930 | No | Form 4 |
| Marquet Magda | Jan 15 | Jan 16 | M · derivative | 11,000 | $26.11 | $287,210 | not reported | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 8 | Jan 9 | S | 2,210 | $44.71 | Sale −$98,809 | 12,835 | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Jan 8 | Jan 9 | S | 2,515 | $44.71 | Sale −$112,446 | 21,852 | No | Form 4 |
| Faga DanielPresident, CEO | Jan 8 | Jan 9 | S | 14,281 | $44.71 | Sale −$638,504 | 479,344 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 8 | Jan 9 | S | 3,650 | $44.71 | Sale −$163,192 | 42,088 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 7 | Jan 9 | M | 5,888 | not reported | not reported | 15,045 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 7 | Jan 9 | M · derivative | 5,888 | $0.00 | $0 | 17,662 | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Jan 7 | Jan 9 | M | 6,700 | not reported | not reported | 24,367 | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Jan 7 | Jan 9 | M · derivative | 6,700 | $0.00 | $0 | 20,100 | No | Form 4 |
| Faga DanielPresident, CEO | Jan 7 | Jan 9 | M | 26,838 | not reported | not reported | 493,625 | No | Form 4 |
| Faga DanielPresident, CEO | Jan 7 | Jan 9 | M · derivative | 26,838 | $0.00 | $0 | 80,512 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 7 | Jan 9 | M | 8,525 | not reported | not reported | 45,738 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 7 | Jan 9 | M · derivative | 8,525 | $0.00 | $0 | 25,575 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 7 | Jan 8 | S | 2,017 | $45.11 | Sale −$90,987 | 16,779 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 7 | Jan 8 | S | 5,281 | $45.38 | Sale −$239,652 | 11,498 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 7 | Jan 8 | S | 1,841 | $46.13 | Sale −$84,925 | 9,657 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 7 | Jan 8 | S | 500 | $47.23 | Sale −$23,615 | 9,157 | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Jan 7 | Jan 8 | S | 1,908 | $45.11 | Sale −$86,070 | 17,667 | No | Form 4 |
| Faga DanielPresident, CEO | Jan 7 | Jan 8 | S | 9,202 | $45.11 | Sale −$415,102 | 466,787 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 7 | Jan 8 | S | 2,235 | $45.11 | Sale −$100,821 | 37,213 | No | Form 4 |
| Fenton Dennis M | Jan 6 | Jan 8 | A · derivative | 5,500 | $43.91 | $241,505 | 5,500 | No | Form 4 |
| Fenton Dennis M | Jan 6 | Jan 8 | A · derivative | 4,000 | $0.00 | $0 | 4,000 | No | Form 4 |
| Renton Hollings | Jan 6 | Jan 8 | A · derivative | 5,500 | $43.91 | $241,505 | 5,500 | No | Form 4 |
| Renton Hollings | Jan 6 | Jan 8 | A · derivative | 4,000 | $0.00 | $0 | 4,000 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 6 | Jan 8 | M | 5,545 | not reported | not reported | 18,796 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 6 | Jan 8 | M · derivative | 5,545 | $0.00 | $0 | 5,545 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 6 | Jan 8 | A · derivative | 17,100 | $0.00 | $0 | 17,100 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 6 | Jan 8 | A · derivative | 23,200 | $43.91 | $1,018,712 | 23,200 | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Jan 6 | Jan 8 | M | 5,245 | not reported | not reported | 19,575 | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Jan 6 | Jan 8 | M · derivative | 5,245 | $0.00 | $0 | 5,245 | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Jan 6 | Jan 8 | A · derivative | 21,400 | $0.00 | $0 | 21,400 | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Jan 6 | Jan 8 | A · derivative | 29,000 | $43.91 | $1,273,390 | 29,000 | No | Form 4 |
| Orwin John A | Jan 6 | Jan 8 | A · derivative | 8,250 | $43.91 | $362,258 | 8,250 | No | Form 4 |
| Orwin John A | Jan 6 | Jan 8 | A · derivative | 6,000 | $0.00 | $0 | 6,000 | No | Form 4 |
| Schmid John P. | Jan 6 | Jan 8 | A · derivative | 5,500 | $43.91 | $241,505 | 5,500 | No | Form 4 |
| Schmid John P. | Jan 6 | Jan 8 | A · derivative | 4,000 | $0.00 | $0 | 4,000 | No | Form 4 |
| Marquet Magda | Jan 6 | Jan 8 | A · derivative | 5,500 | $43.91 | $241,505 | 5,500 | No | Form 4 |
| Marquet Magda | Jan 6 | Jan 8 | A · derivative | 4,000 | $0.00 | $0 | 4,000 | No | Form 4 |
| Faga DanielPresident, CEO | Jan 6 | Jan 8 | M | 17,850 | not reported | not reported | 475,989 | No | Form 4 |
| Faga DanielPresident, CEO | Jan 6 | Jan 8 | M · derivative | 17,850 | $0.00 | $0 | 17,850 | No | Form 4 |
| Faga DanielPresident, CEO | Jan 6 | Jan 8 | A · derivative | 98,600 | $0.00 | $0 | 98,600 | No | Form 4 |
| Faga DanielPresident, CEO | Jan 6 | Jan 8 | A · derivative | 133,400 | $43.91 | $5,857,594 | 133,400 | No | Form 4 |
| Jain Rita | Jan 6 | Jan 8 | A · derivative | 5,500 | $43.91 | $241,505 | 5,500 | No | Form 4 |
| Jain Rita | Jan 6 | Jan 8 | A · derivative | 4,000 | $0.00 | $0 | 4,000 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 6 | Jan 8 | M | 6,145 | not reported | not reported | 39,448 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 6 | Jan 8 | M · derivative | 6,145 | $0.00 | $0 | 6,145 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 6 | Jan 8 | A · derivative | 21,400 | $0.00 | $0 | 21,400 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 6 | Jan 8 | A · derivative | 29,000 | $43.91 | $1,273,390 | 29,000 | No | Form 4 |
| Ware J. Anthony | Jan 6 | Jan 8 | A · derivative | 5,500 | $43.91 | $241,505 | 5,500 | No | Form 4 |
| Ware J. Anthony | Jan 6 | Jan 8 | A · derivative | 4,000 | $0.00 | $0 | 4,000 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 5 | Jan 6 | S | 2,983 | $43.26 | Sale −$129,045 | 13,251 | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Jan 5 | Jan 6 | S | 3,363 | $43.26 | Sale −$145,483 | 14,330 | No | Form 4 |
| Faga DanielPresident, CEO | Jan 5 | Jan 6 | S | 15,309 | $43.26 | Sale −$662,267 | 458,139 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 5 | Jan 6 | S | 4,219 | $43.26 | Sale −$182,514 | 33,303 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 3 | Jan 6 | M | 7,287 | not reported | not reported | 16,234 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 3 | Jan 6 | M · derivative | 7,287 | $0.00 | $0 | 14,575 | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Jan 3 | Jan 6 | M | 8,292 | not reported | not reported | 17,693 | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Jan 3 | Jan 6 | M · derivative | 8,292 | $0.00 | $0 | 16,585 | No | Form 4 |
| Faga DanielPresident, CEO | Jan 3 | Jan 6 | M | 34,677 | not reported | not reported | 473,448 | No | Form 4 |
| Faga DanielPresident, CEO | Jan 3 | Jan 6 | M · derivative | 34,677 | $0.00 | $0 | 69,355 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 3 | Jan 6 | M | 10,555 | not reported | not reported | 37,522 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 3 | Jan 6 | M · derivative | 10,555 | $0.00 | $0 | 21,110 | No | Form 4 |
| Schmid John P. | Dec 23, 2025 | Dec 23, 2025 | J | 11,068 | $51.00 | $564,468 | not reported | No | Form 4 |
| Ware J. Anthony | Dec 23, 2025 | Dec 23, 2025 | S | 3,900 | $49.58 | Sale −$193,362 | 9,630 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Dec 22, 2025 | Dec 23, 2025 | M | 10,000 | $14.02 | $140,200 | 18,947 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Dec 22, 2025 | Dec 23, 2025 | S | 10,000 | $51.00 | Sale −$510,000 | 8,947 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Dec 22, 2025 | Dec 23, 2025 | M · derivative | 10,000 | $14.02 | $140,200 | 43,000 | Yes | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Dec 22, 2025 | Dec 23, 2025 | M | 10,000 | $20.16 | $201,600 | 19,401 | Yes | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Dec 22, 2025 | Dec 23, 2025 | S | 10,000 | $50.00 | Sale −$500,000 | 9,401 | Yes | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Dec 22, 2025 | Dec 23, 2025 | M · derivative | 10,000 | $20.16 | $201,600 | 60,600 | Yes | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Dec 22, 2025 | Dec 23, 2025 | M | 1,500 | $18.50 | $27,750 | 28,467 | Yes | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Dec 22, 2025 | Dec 23, 2025 | S | 1,500 | $50.00 | Sale −$75,000 | 26,967 | Yes | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Dec 22, 2025 | Dec 23, 2025 | M · derivative | 1,500 | $18.50 | $27,750 | 83,500 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Dec 18, 2025 | Dec 18, 2025 | S | 141 | $46.99 | Sale −$6,626 | 8,947 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Dec 17, 2025 | Dec 18, 2025 | M | 10,000 | $14.02 | $140,200 | 19,088 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Dec 17, 2025 | Dec 18, 2025 | S | 10,000 | $46.00 | Sale −$460,000 | 9,088 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Dec 17, 2025 | Dec 18, 2025 | M · derivative | 10,000 | $14.02 | $140,200 | 53,000 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Dec 16, 2025 | Dec 18, 2025 | M | 5,000 | $14.02 | $70,100 | 14,088 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Dec 16, 2025 | Dec 18, 2025 | M | 7,500 | $20.16 | $151,200 | 21,588 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Dec 16, 2025 | Dec 18, 2025 | S | 8,305 | $44.68 | Sale −$371,067 | 13,283 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Dec 16, 2025 | Dec 18, 2025 | S | 4,195 | $45.24 | Sale −$189,782 | 9,088 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Dec 16, 2025 | Dec 18, 2025 | M · derivative | 5,000 | $14.02 | $70,100 | 63,000 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Dec 16, 2025 | Dec 18, 2025 | M · derivative | 7,500 | $20.16 | $151,200 | not reported | Yes | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Dec 16, 2025 | Dec 18, 2025 | M | 10,000 | $20.16 | $201,600 | 25,126 | Yes | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Dec 16, 2025 | Dec 18, 2025 | S | 9,365 | $44.62 | Sale −$417,866 | 15,761 | Yes | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Dec 16, 2025 | Dec 18, 2025 | S | 6,360 | $45.21 | Sale −$287,536 | 9,401 | Yes | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Dec 16, 2025 | Dec 18, 2025 | M · derivative | 10,000 | $20.16 | $201,600 | 70,600 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Sep 30, 2025 | Oct 1, 2025 | M | 5,000 | $14.02 | $70,100 | 17,328 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Sep 30, 2025 | Oct 1, 2025 | S | 8,240 | $29.00 | Sale −$238,960 | 9,088 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Sep 30, 2025 | Oct 1, 2025 | M · derivative | 5,000 | $14.02 | $70,100 | 68,000 | Yes | Form 4 |
| Orwin John A | Sep 15, 2025 | Sep 17, 2025 | M | 1,300 | $0.00 | $0 | 10,665 | No | Form 4 |
| Orwin John A | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 1,300 | $0.00 | $0 | 1,300 | No | Form 4 |
| Renton Hollings | Aug 8, 2025 | Aug 12, 2025 | M | 10,231 | $6.93 | $70,901 | 15,196 | Yes | Form 4 |
| Renton Hollings | Aug 8, 2025 | Aug 12, 2025 | S | 3,110 | $19.44 | Sale −$60,458 | 12,086 | Yes | Form 4 |
| Renton Hollings | Aug 8, 2025 | Aug 12, 2025 | S | 7,121 | $19.70 | Sale −$140,284 | 4,965 | Yes | Form 4 |
| Renton Hollings | Aug 8, 2025 | Aug 12, 2025 | M · derivative | 10,231 | $6.93 | $70,901 | not reported | Yes | Form 4 |
| Renton Hollings | Jul 2, 2025 | Jul 3, 2025 | M | 20,925 | $6.93 | $145,010 | 25,890 | Yes | Form 4 |
| Renton Hollings | Jul 2, 2025 | Jul 3, 2025 | S | 7,250 | $23.09 | Sale −$167,403 | 18,640 | Yes | Form 4 |
| Renton Hollings | Jul 2, 2025 | Jul 3, 2025 | S | 13,675 | $23.82 | Sale −$325,739 | 4,965 | Yes | Form 4 |
| Renton Hollings | Jul 2, 2025 | Jul 3, 2025 | M · derivative | 20,925 | $6.93 | $145,010 | not reported | Yes | Form 4 |
| Renton Hollings | Jun 18, 2025 | Jun 20, 2025 | S | 3,015 | $23.97 | Sale −$72,270 | 4,965 | Yes | Form 4 |
| Fenton Dennis M | Jun 18, 2025 | Jun 20, 2025 | S | 3,015 | $23.97 | Sale −$72,270 | 4,965 | Yes | Form 4 |
| Ware J. Anthony | Jun 15, 2025 | Jun 17, 2025 | M | 6,030 | $0.00 | $0 | 13,530 | No | Form 4 |
| Ware J. Anthony | Jun 15, 2025 | Jun 17, 2025 | M · derivative | 6,030 | $0.00 | $0 | not reported | No | Form 4 |
| Schmid John P. | Jun 15, 2025 | Jun 17, 2025 | M | 6,030 | $0.00 | $0 | 52,267 | No | Form 4 |
| Schmid John P. | Jun 15, 2025 | Jun 17, 2025 | M · derivative | 6,030 | $0.00 | $0 | not reported | No | Form 4 |
| Renton Hollings | Jun 15, 2025 | Jun 17, 2025 | M | 6,030 | $0.00 | $0 | 7,980 | No | Form 4 |
| Renton Hollings | Jun 15, 2025 | Jun 17, 2025 | M · derivative | 6,030 | $0.00 | $0 | not reported | No | Form 4 |
| Orwin John A | Jun 15, 2025 | Jun 17, 2025 | M | 6,030 | $0.00 | $0 | 9,365 | No | Form 4 |
| Orwin John A | Jun 15, 2025 | Jun 17, 2025 | M · derivative | 6,030 | $0.00 | $0 | not reported | No | Form 4 |
| Marquet Magda | Jun 15, 2025 | Jun 17, 2025 | M | 6,030 | $0.00 | $0 | 9,930 | No | Form 4 |
| Marquet Magda | Jun 15, 2025 | Jun 17, 2025 | M · derivative | 6,030 | $0.00 | $0 | not reported | No | Form 4 |
| Fenton Dennis M | Jun 15, 2025 | Jun 17, 2025 | M | 6,030 | $0.00 | $0 | 7,980 | No | Form 4 |
| Fenton Dennis M | Jun 15, 2025 | Jun 17, 2025 | M · derivative | 6,030 | $0.00 | $0 | not reported | No | Form 4 |
| Jain Rita | Jun 15, 2025 | Jun 17, 2025 | M | 7,330 | $0.00 | $0 | 11,864 | No | Form 4 |
| Jain Rita | Jun 15, 2025 | Jun 17, 2025 | M · derivative | 1,300 | $0.00 | $0 | 1,300 | No | Form 4 |
| Jain Rita | Jun 15, 2025 | Jun 17, 2025 | M · derivative | 6,030 | $0.00 | $0 | not reported | No | Form 4 |
| Schmid John P. | Mar 25, 2025 | Mar 27, 2025 | J | 11,068 | $18.18 | $201,216 | 11,068 | No | Form 4 |
| Schmid John P. | Jan 13, 2025 | Jan 15, 2025 | M | 21,692 | $4.55 | $98,699 | 25,592 | No | Form 4 |
| Schmid John P. | Jan 13, 2025 | Jan 15, 2025 | M | 20,645 | $8.54 | $176,308 | 46,237 | No | Form 4 |
| Schmid John P. | Jan 13, 2025 | Jan 15, 2025 | M · derivative | 21,692 | $4.55 | $98,699 | not reported | No | Form 4 |
| Schmid John P. | Jan 13, 2025 | Jan 15, 2025 | M · derivative | 20,645 | $8.54 | $176,308 | not reported | No | Form 4 |
| Faga DanielPresident, CEO | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 107,350 | $0.00 | $0 | 107,350 | No | Form 4 |
| Faga DanielPresident, CEO | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 305,500 | $14.83 | $4,530,565 | 305,500 | No | Form 4 |
| Ware J. Anthony | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 16,510 | $14.83 | $244,843 | 16,510 | No | Form 4 |
| Ware J. Anthony | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 6,030 | $0.00 | $0 | 6,030 | No | Form 4 |
| Schmid John P. | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 16,510 | $14.83 | $244,843 | 16,510 | No | Form 4 |
| Schmid John P. | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 6,030 | $0.00 | $0 | 6,030 | No | Form 4 |
| Renton Hollings | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 16,510 | $14.83 | $244,843 | 16,510 | No | Form 4 |
| Renton Hollings | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 6,030 | $0.00 | $0 | 6,030 | No | Form 4 |
| Orwin John A | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 16,510 | $14.83 | $244,843 | 16,510 | No | Form 4 |
| Orwin John A | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 6,030 | $0.00 | $0 | 6,030 | No | Form 4 |
| Marquet Magda | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 16,510 | $14.83 | $244,843 | 16,510 | No | Form 4 |
| Marquet Magda | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 6,030 | $0.00 | $0 | 6,030 | No | Form 4 |
| Jain Rita | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 16,510 | $14.83 | $244,843 | 16,510 | No | Form 4 |
| Jain Rita | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 6,030 | $0.00 | $0 | 6,030 | No | Form 4 |
| Fenton Dennis M | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 16,510 | $14.83 | $244,843 | 16,510 | No | Form 4 |
| Fenton Dennis M | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 6,030 | $0.00 | $0 | 6,030 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 23,550 | $0.00 | $0 | 23,550 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 67,000 | $14.83 | $993,610 | 67,000 | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 26,800 | $0.00 | $0 | 26,800 | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 76,400 | $14.83 | $1,133,012 | 76,400 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 34,100 | $0.00 | $0 | 34,100 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 7, 2025 | Jan 7, 2025 | A · derivative | 97,200 | $14.83 | $1,441,476 | 97,200 | No | Form 4 |
| Faga DanielPresident, CEO | Jan 6, 2025 | Jan 7, 2025 | M | 17,850 | not reported | not reported | 442,853 | No | Form 4 |
| Faga DanielPresident, CEO | Jan 6, 2025 | Jan 7, 2025 | F | 6,387 | $15.30 | $97,721 | 436,466 | No | Form 4 |
| Faga DanielPresident, CEO | Jan 6, 2025 | Jan 7, 2025 | M · derivative | 17,850 | $0.00 | $0 | 35,700 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 6, 2025 | Jan 7, 2025 | M | 5,545 | not reported | not reported | 13,220 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 6, 2025 | Jan 7, 2025 | F | 2,217 | $15.30 | $33,920 | 11,003 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 6, 2025 | Jan 7, 2025 | M · derivative | 5,545 | $0.00 | $0 | 11,090 | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Jan 6, 2025 | Jan 7, 2025 | M | 5,245 | not reported | not reported | 15,856 | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Jan 6, 2025 | Jan 7, 2025 | F | 2,054 | $15.30 | $31,426 | 13,802 | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Jan 6, 2025 | Jan 7, 2025 | M · derivative | 5,245 | $0.00 | $0 | 10,490 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 6, 2025 | Jan 7, 2025 | M | 6,145 | not reported | not reported | 27,904 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 6, 2025 | Jan 7, 2025 | F | 2,261 | $15.30 | $34,593 | 25,643 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 6, 2025 | Jan 7, 2025 | M · derivative | 6,145 | $0.00 | $0 | 12,290 | No | Form 4 |
| Faga DanielPresident, CEO | Jan 3, 2025 | Jan 7, 2025 | M | 34,678 | not reported | not reported | 438,036 | No | Form 4 |
| Faga DanielPresident, CEO | Jan 3, 2025 | Jan 7, 2025 | F | 13,033 | $14.60 | $190,282 | 425,003 | No | Form 4 |
| Faga DanielPresident, CEO | Jan 3, 2025 | Jan 7, 2025 | M · derivative | 34,678 | $0.00 | $0 | 104,032 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 3, 2025 | Jan 7, 2025 | M | 7,288 | not reported | not reported | 10,669 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 3, 2025 | Jan 7, 2025 | F | 2,994 | $14.60 | $43,712 | 7,675 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jan 3, 2025 | Jan 7, 2025 | M · derivative | 7,288 | $0.00 | $0 | 21,862 | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Jan 3, 2025 | Jan 7, 2025 | M | 8,293 | not reported | not reported | 14,018 | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Jan 3, 2025 | Jan 7, 2025 | F | 3,407 | $14.60 | $49,742 | 10,611 | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Jan 3, 2025 | Jan 7, 2025 | M · derivative | 8,293 | $0.00 | $0 | 24,877 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 3, 2025 | Jan 7, 2025 | M | 10,555 | not reported | not reported | 26,095 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 3, 2025 | Jan 7, 2025 | F | 4,336 | $14.60 | $63,306 | 21,759 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 3, 2025 | Jan 7, 2025 | M · derivative | 10,555 | $0.00 | $0 | 31,665 | No | Form 4 |
| EcoR1 Capital, LLC | Jan 2, 2025 | Jan 2, 2025 | P | 6,646 | $12.95 | Purchase +$86,066 | 7,880,094 | No | Form 4 |
| EcoR1 Capital, LLC | Dec 31, 2024 | Jan 2, 2025 | P | 13,268 | $12.93 | Purchase +$171,555 | 7,873,448 | No | Form 4 |
| EcoR1 Capital, LLC | Dec 30, 2024 | Jan 2, 2025 | P | 65,184 | $12.92 | Purchase +$842,177 | 7,860,180 | No | Form 4 |
| Renton Hollings | Nov 29, 2024 | Dec 3, 2024 | M | 10,000 | $6.93 | $69,300 | 11,950 | Yes | Form 4 |
| Renton Hollings | Nov 29, 2024 | Dec 3, 2024 | S | 10,000 | $25.00 | Sale −$250,000 | 1,950 | Yes | Form 4 |
| Renton Hollings | Nov 29, 2024 | Dec 3, 2024 | M · derivative | 10,000 | $6.93 | $69,300 | 20,925 | Yes | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Sep 23, 2024 | Sep 24, 2024 | M | 1,500 | $18.50 | $27,750 | 16,898 | Yes | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Sep 23, 2024 | Sep 24, 2024 | S | 1,500 | $38.67 | Sale −$58,005 | 15,398 | Yes | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Sep 23, 2024 | Sep 24, 2024 | M · derivative | 1,500 | $18.50 | $27,750 | 85,000 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Sep 17, 2024 | Sep 17, 2024 | S | 3,780 | $38.41 | Sale −$145,190 | 3,240 | Yes | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Sep 16, 2024 | Sep 17, 2024 | S | 2,220 | $38.93 | Sale −$86,425 | 4,744 | Yes | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Sep 16, 2024 | Sep 17, 2024 | M | 10,000 | $20.16 | $201,600 | 14,744 | Yes | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Sep 16, 2024 | Sep 17, 2024 | S | 10,000 | $40.13 | Sale −$401,300 | 4,744 | Yes | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Sep 16, 2024 | Sep 17, 2024 | M · derivative | 10,000 | $20.16 | $201,600 | 80,600 | Yes | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Sep 16, 2024 | Sep 17, 2024 | S | 2,220 | $38.93 | Sale −$86,425 | 15,398 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Sep 16, 2024 | Sep 17, 2024 | S | 2,220 | $38.93 | Sale −$86,425 | 8,520 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Sep 16, 2024 | Sep 17, 2024 | M | 5,000 | $14.02 | $70,100 | 13,520 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Sep 16, 2024 | Sep 17, 2024 | S | 6,500 | $40.13 | Sale −$260,845 | 7,020 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Sep 16, 2024 | Sep 17, 2024 | M · derivative | 5,000 | $14.02 | $70,100 | 73,000 | Yes | Form 4 |
| Orwin John A | Sep 15, 2024 | Sep 17, 2024 | M | 1,300 | $0.00 | $0 | 3,335 | No | Form 4 |
| Orwin John A | Sep 15, 2024 | Sep 17, 2024 | M · derivative | 1,300 | $0.00 | $0 | 2,600 | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Sep 14, 2024 | Sep 17, 2024 | M | 6,000 | not reported | not reported | 6,964 | Yes | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Sep 14, 2024 | Sep 17, 2024 | M · derivative | 6,000 | $0.00 | $0 | not reported | Yes | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Sep 14, 2024 | Sep 17, 2024 | M | 6,000 | not reported | not reported | 17,618 | Yes | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Sep 14, 2024 | Sep 17, 2024 | M · derivative | 6,000 | $0.00 | $0 | not reported | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Sep 14, 2024 | Sep 17, 2024 | M | 6,000 | $0.00 | $0 | 10,740 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Sep 14, 2024 | Sep 17, 2024 | M · derivative | 6,000 | $0.00 | $0 | not reported | Yes | Form 4 |
| EcoR1 Capital, LLC | Aug 14, 2024 | Aug 16, 2024 | P | 273,972 | $36.50 | Purchase +$9,999,978 | 7,794,996 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Aug 14, 2024 | Aug 16, 2024 | M | 2,000 | $18.50 | $37,000 | 13,618 | Yes | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Aug 14, 2024 | Aug 16, 2024 | S | 2,000 | $40.00 | Sale −$80,000 | 11,618 | Yes | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Aug 14, 2024 | Aug 16, 2024 | M · derivative | 2,000 | $18.50 | $37,000 | 86,500 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Jul 22, 2024 | Jul 24, 2024 | A · derivative | 20,000 | $0.00 | $0 | 20,000 | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Jul 22, 2024 | Jul 24, 2024 | A · derivative | 20,000 | $0.00 | $0 | 20,000 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jul 22, 2024 | Jul 24, 2024 | A · derivative | 50,000 | $0.00 | $0 | 50,000 | No | Form 4 |
| Faga DanielCEO | Jul 22, 2024 | Jul 24, 2024 | A · derivative | 160,000 | $0.00 | $0 | 160,000 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jul 18, 2024 | Jul 19, 2024 | M | 1,500 | $18.50 | $27,750 | 13,118 | Yes | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jul 18, 2024 | Jul 19, 2024 | S | 1,500 | $35.00 | Sale −$52,500 | 11,618 | Yes | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jul 18, 2024 | Jul 19, 2024 | M · derivative | 1,500 | $18.50 | $27,750 | 88,500 | Yes | Form 4 |
| Renton Hollings | Jul 15, 2024 | Jul 17, 2024 | M | 10,000 | $6.93 | $69,300 | 11,950 | Yes | Form 4 |
| Renton Hollings | Jul 15, 2024 | Jul 17, 2024 | S | 7,103 | $30.50 | Sale −$216,642 | 4,847 | Yes | Form 4 |
| Renton Hollings | Jul 15, 2024 | Jul 17, 2024 | S | 2,897 | $30.98 | Sale −$89,749 | 1,950 | Yes | Form 4 |
| Renton Hollings | Jul 15, 2024 | Jul 17, 2024 | M · derivative | 10,000 | $6.93 | $69,300 | 30,925 | Yes | Form 4 |
| Fenton Dennis M | Jun 21, 2024 | Jun 24, 2024 | S | 1,950 | $23.17 | Sale −$45,182 | 1,950 | Yes | Form 4 |
| Renton Hollings | Jun 18, 2024 | Jun 18, 2024 | S | 1,950 | $23.16 | Sale −$45,162 | 1,950 | No | Form 4 |
| Jain Rita | Jun 15, 2024 | Jun 18, 2024 | M | 4,534 | $0.00 | $0 | 4,534 | No | Form 4 |
| Jain Rita | Jun 15, 2024 | Jun 18, 2024 | M · derivative | 3,234 | $0.00 | $0 | not reported | No | Form 4 |
| Jain Rita | Jun 15, 2024 | Jun 18, 2024 | M · derivative | 1,300 | $0.00 | $0 | not reported | No | Form 4 |
| Renton Hollings | Jun 15, 2024 | Jun 18, 2024 | M | 3,900 | $0.00 | $0 | 3,900 | No | Form 4 |
| Renton Hollings | Jun 15, 2024 | Jun 18, 2024 | M · derivative | 3,900 | $0.00 | $0 | not reported | No | Form 4 |
| Orwin John A | Jun 15, 2024 | Jun 18, 2024 | M | 2,035 | $0.00 | $0 | 2,035 | No | Form 4 |
| Orwin John A | Jun 15, 2024 | Jun 18, 2024 | M · derivative | 2,035 | $0.00 | $0 | not reported | No | Form 4 |
| Ware J. Anthony | Jun 15, 2024 | Jun 18, 2024 | M | 3,900 | $0.00 | $0 | 7,500 | No | Form 4 |
| Ware J. Anthony | Jun 15, 2024 | Jun 18, 2024 | M · derivative | 3,900 | $0.00 | $0 | not reported | No | Form 4 |
| Schmid John P. | Jun 15, 2024 | Jun 18, 2024 | M | 3,900 | $0.00 | $0 | 3,900 | No | Form 4 |
| Schmid John P. | Jun 15, 2024 | Jun 18, 2024 | M · derivative | 3,900 | $0.00 | $0 | not reported | No | Form 4 |
| Marquet Magda | Jun 15, 2024 | Jun 18, 2024 | M | 3,900 | $0.00 | $0 | 3,900 | No | Form 4 |
| Marquet Magda | Jun 15, 2024 | Jun 18, 2024 | M · derivative | 3,900 | $0.00 | $0 | not reported | No | Form 4 |
| Fenton Dennis M | Jun 15, 2024 | Jun 18, 2024 | M | 3,900 | $0.00 | $0 | 3,900 | No | Form 4 |
| Fenton Dennis M | Jun 15, 2024 | Jun 18, 2024 | M · derivative | 3,900 | $0.00 | $0 | not reported | No | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | May 22, 2024 | May 24, 2024 | S | 1,500 | $23.72 | Sale −$35,580 | 964 | Yes | Form 4 |
| Faga DanielCEO | Mar 26, 2024 | Mar 26, 2024 | F | 347,441 | $21.60 | $7,504,726 | 401,646 | No | Form 4 |
| Faga DanielCEO | Mar 25, 2024 | Mar 26, 2024 | S | 3,000 | $21.42 | Sale −$64,260 | 749,087 | No | Form 4 |
| Faga DanielCEO | Mar 22, 2024 | Mar 26, 2024 | S | 145,940 | $22.78 | Sale −$3,324,513 | 752,087 | No | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Feb 16, 2024 | Feb 21, 2024 | M | 5,000 | $14.02 | $70,100 | 8,240 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Feb 16, 2024 | Feb 21, 2024 | S | 5,000 | $25.00 | Sale −$125,000 | 3,240 | Yes | Form 4 |
| Loumeau Eric JCHIEF LEGAL OFFICER | Feb 16, 2024 | Feb 21, 2024 | M · derivative | 5,000 | $14.02 | $70,100 | 78,000 | Yes | Form 4 |
| Mulroy DennisCHIEF FINANCIAL OFFICER | Jan 30, 2024 | Feb 1, 2024 | S | 3,065 | $23.63 | Sale −$72,426 | 964 | No | Form 4 |
| Faga DanielCEO | Jan 8, 2024 | Jan 9, 2024 | S | 6,866 | $21.81 | Sale −$149,747 | 898,027 | No | Form 4 |
| Mulroy DennisChief Financial Officer | Jan 8, 2024 | Jan 9, 2024 | S | 2,180 | $21.81 | Sale −$47,546 | 4,029 | No | Form 4 |
| Loumeau Eric JChief Legal Officer | Jan 8, 2024 | Jan 9, 2024 | S | 2,305 | $21.81 | Sale −$50,272 | 3,240 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 8, 2024 | Jan 9, 2024 | S | 2,554 | $21.81 | Sale −$55,703 | 10,118 | No | Form 4 |
| Faga DanielCEO | Jan 6, 2024 | Jan 9, 2024 | M | 17,850 | $0.00 | $0 | 904,893 | No | Form 4 |
| Faga DanielCEO | Jan 6, 2024 | Jan 9, 2024 | M · derivative | 17,850 | $0.00 | $0 | 53,550 | No | Form 4 |
| Mulroy DennisChief Financial Officer | Jan 6, 2024 | Jan 9, 2024 | M | 5,245 | $0.00 | $0 | 6,209 | No | Form 4 |
| Mulroy DennisChief Financial Officer | Jan 6, 2024 | Jan 9, 2024 | M · derivative | 5,245 | $0.00 | $0 | 15,735 | No | Form 4 |
| Loumeau Eric JChief Legal Officer | Jan 6, 2024 | Jan 9, 2024 | M | 5,545 | $0.00 | $0 | 5,545 | No | Form 4 |
| Loumeau Eric JChief Legal Officer | Jan 6, 2024 | Jan 9, 2024 | M · derivative | 5,545 | $0.00 | $0 | 16,635 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 6, 2024 | Jan 9, 2024 | M | 6,145 | $0.00 | $0 | 12,672 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 6, 2024 | Jan 9, 2024 | M · derivative | 6,145 | $0.00 | $0 | 18,435 | No | Form 4 |
| Ware J. Anthony | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 16,510 | $21.19 | $349,847 | 16,510 | No | Form 4 |
| Ware J. Anthony | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 6,030 | $0.00 | $0 | 6,030 | No | Form 4 |
| Faga DanielCEO | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 379,620 | $21.19 | $8,044,148 | 379,620 | No | Form 4 |
| Faga DanielCEO | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 138,710 | $0.00 | $0 | 138,710 | No | Form 4 |
| Fenton Dennis M | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 16,510 | $21.19 | $349,847 | 16,510 | No | Form 4 |
| Fenton Dennis M | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 6,030 | $0.00 | $0 | 6,030 | No | Form 4 |
| Mulroy DennisChief Financial Officer | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 90,780 | $21.19 | $1,923,628 | 90,780 | No | Form 4 |
| Mulroy DennisChief Financial Officer | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 33,170 | $0.00 | $0 | 33,170 | No | Form 4 |
| Loumeau Eric JChief Legal Officer | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 79,780 | $21.19 | $1,690,538 | 79,780 | No | Form 4 |
| Loumeau Eric JChief Legal Officer | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 29,150 | $0.00 | $0 | 29,150 | No | Form 4 |
| Renton Hollings | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 16,510 | $21.19 | $349,847 | 16,510 | No | Form 4 |
| Renton Hollings | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 6,030 | $0.00 | $0 | 6,030 | No | Form 4 |
| Orwin John A | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 16,510 | $21.19 | $349,847 | 16,510 | No | Form 4 |
| Orwin John A | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 6,030 | $0.00 | $0 | 6,030 | No | Form 4 |
| Schmid John P. | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 16,510 | $21.19 | $349,847 | 16,510 | No | Form 4 |
| Schmid John P. | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 6,030 | $0.00 | $0 | 6,030 | No | Form 4 |
| Marquet Magda | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 16,510 | $21.19 | $349,847 | 16,510 | No | Form 4 |
| Marquet Magda | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 6,030 | $0.00 | $0 | 6,030 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 115,540 | $21.19 | $2,448,293 | 115,540 | No | Form 4 |
| Lizzul Paul F.Chief Medical Officer | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 42,220 | $0.00 | $0 | 42,220 | No | Form 4 |
| Jain Rita | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 16,510 | $21.19 | $349,847 | 16,510 | No | Form 4 |
| Jain Rita | Jan 3, 2024 | Jan 5, 2024 | A · derivative | 6,030 | $0.00 | $0 | 6,030 | No | Form 4 |
| Loumeau Eric JChief Legal Officer | Nov 22, 2023 | Nov 27, 2023 | S | 882 | $14.19 | Sale −$12,516 | not reported | No | Form 4 |