ANTXAN2 Therapeutics, Inc.
- Market cap
- $133.96M
- as of 2026-10-23
- Latest close
- $3.55
- as of 2026-10-23
- Sector
- Healthcare
- as of 2026-10-24
- Industry
- Biotechnology
- as of 2026-10-24
Cluster
No cluster in the last 90 days under the default rule (14d · ≥2 insiders · all roles).
Form 4 historysince 2023-10-03
Dashed line = amended filing (Form 4/A)
| Insider | Traded | Filed | Type | Shares | Price | Value | Owned after | 10b5-1 plan | Filing |
|---|---|---|---|---|---|---|---|---|---|
| Marks Gilbert Lynn | Oct 12 | Oct 13 | A | 2,283 | $0.00 | $0 | 84,156 | No | Form 4 |
| Martin Patricia A. | Oct 12 | Oct 13 | A | 389 | $0.00 | $0 | 19,252 | No | Form 4 |
| Aziz Kabeer | Oct 12 | Oct 13 | A | 2,465 | $0.00 | $0 | 61,571 | No | Form 4 |
| Trenor Cameron C. IIIChief Medical Officer | Sep 15 | Sep 16 | A | 116,667 | $0.00 | $0 | 116,667 | No | Form 4 |
| Trenor Cameron C. IIIChief Medical Officer | Sep 15 | Sep 16 | A · derivative | 233,333 | $5.36 | $1,250,665 | 233,333 | No | Form 4 |
| Readnour Robin Shane | Sep 9 | Sep 11 | S | 523 | $6.02 | Sale −$3,148 | 557,467 | Yes | Form 4 |
| Readnour Robin Shane | Sep 9 | Sep 11 | S | 585 | $6.02 | Sale −$3,522 | 624,765 | Yes | Form 4 |
| Readnour Robin Shane | Sep 8 | Sep 8 | S | 4,725 | $6.02 | Sale −$28,445 | 557,990 | Yes | Form 4 |
| Readnour Robin Shane | Sep 8 | Sep 8 | S | 5,294 | $6.02 | Sale −$31,870 | 625,350 | Yes | Form 4 |
| Readnour Robin Shane | Sep 3 | Sep 8 | S | 2,877 | $6.07 | Sale −$17,463 | 562,715 | Yes | Form 4 |
| Readnour Robin Shane | Sep 3 | Sep 8 | S | 3,223 | $6.07 | Sale −$19,564 | 630,644 | Yes | Form 4 |
| Williams Sarah JoannePrincipal Accounting Officer | Sep 1 | Sep 4 | S | 272 | $5.53 | Sale −$1,504 | 66,311 | No | Form 4 |
| FitzPatrick Margaret M | Sep 1 | Sep 2 | P | 2,098 | $5.53 | Purchase +$11,602 | 10,708 | No | Form 4 |
| Readnour Robin Shane | Aug 17 | Aug 19 | S | 16,696 | $6.01 | Sale −$100,343 | 565,592 | Yes | Form 4 |
| Readnour Robin Shane | Aug 17 | Aug 19 | S | 18,706 | $6.01 | Sale −$112,423 | 633,867 | Yes | Form 4 |
| Zakrzewski Joseph S | Aug 14 | Aug 14 | G | 405,880 | $0.00 | $0 | not reported | No | Form 4 |
| Martin Patricia A. | Jul 10 | Jul 10 | A | 766 | $0.00 | $0 | 18,863 | No | Form 4 |
| Marks Gilbert Lynn | Jul 10 | Jul 10 | A | 2,789 | $0.00 | $0 | 81,873 | No | Form 4 |
| Aziz Kabeer | Jul 10 | Jul 10 | A | 2,852 | $0.00 | $0 | 59,106 | No | Form 4 |
| Eizen Joshua MSee Remarks | Jul 8 | Jul 10 | S | 5,945 | $4.17 | Sale −$24,791 | 206,554 | No | Form 4 |
| Williams Sarah JoannePrincipal Accounting Officer | May 29 | Jun 2 | S | 265 | $4.43 | Sale −$1,174 | 66,583 | No | Form 4 |
| Martin Patricia A. | Apr 10 | Apr 10 | A | 1,192 | $0.00 | $0 | 18,097 | No | Form 4 |
| Marks Gilbert Lynn | Apr 10 | Apr 10 | A | 3,775 | $0.00 | $0 | 79,084 | No | Form 4 |
| Aziz Kabeer | Apr 10 | Apr 10 | A | 3,775 | $0.00 | $0 | 56,254 | No | Form 4 |
| Easom EricChief Executive Officer | Mar 19 | Mar 23 | A · derivative | 249,999 | $3.91 | $977,496 | 249,999 | No | Form 4 |
| Easom EricChief Executive Officer | Mar 19 | Mar 23 | D · derivative | 249,999 | $6.60 | $1,649,993 | not reported | No | Form 4 |
| Easom EricChief Executive Officer | Mar 19 | Mar 23 | A · derivative | 225,000 | $3.91 | $879,750 | 225,000 | No | Form 4 |
| Easom EricChief Executive Officer | Mar 19 | Mar 23 | D · derivative | 225,000 | $17.28 | $3,888,000 | not reported | No | Form 4 |
| Easom EricChief Executive Officer | Mar 19 | Mar 23 | A · derivative | 267,650 | $3.91 | $1,046,512 | 267,650 | No | Form 4 |
| Easom EricChief Executive Officer | Mar 19 | Mar 23 | D · derivative | 267,650 | $11.99 | $3,209,124 | not reported | No | Form 4 |
| Readnour Robin Shane | Mar 19 | Mar 23 | A · derivative | 20,724 | $3.91 | $81,031 | 20,724 | No | Form 4 |
| Readnour Robin Shane | Mar 19 | Mar 23 | D · derivative | 20,724 | $17.28 | $358,111 | not reported | No | Form 4 |
| Readnour Robin Shane | Mar 19 | Mar 23 | A · derivative | 23,742 | $3.91 | $92,831 | 23,742 | No | Form 4 |
| Readnour Robin Shane | Mar 19 | Mar 23 | D · derivative | 23,742 | $5.91 | $140,315 | not reported | No | Form 4 |
| Spigelman Melvin K | Mar 19 | Mar 23 | A · derivative | 16,941 | $3.91 | $66,239 | 16,941 | No | Form 4 |
| Spigelman Melvin K | Mar 19 | Mar 23 | D · derivative | 16,941 | $9.31 | $157,721 | not reported | No | Form 4 |
| Spigelman Melvin K | Mar 19 | Mar 23 | A · derivative | 10,362 | $3.91 | $40,515 | 10,362 | No | Form 4 |
| Spigelman Melvin K | Mar 19 | Mar 23 | D · derivative | 10,362 | $17.28 | $179,055 | not reported | No | Form 4 |
| Spigelman Melvin K | Mar 19 | Mar 23 | A · derivative | 23,742 | $3.91 | $92,831 | 23,742 | No | Form 4 |
| Spigelman Melvin K | Mar 19 | Mar 23 | D · derivative | 23,742 | $5.91 | $140,315 | not reported | No | Form 4 |
| Eizen Joshua MSee Remarks | Mar 19 | Mar 23 | A · derivative | 92,000 | $3.91 | $359,720 | 92,000 | No | Form 4 |
| Eizen Joshua MSee Remarks | Mar 19 | Mar 23 | D · derivative | 92,000 | $17.88 | $1,644,960 | not reported | No | Form 4 |
| Eizen Joshua MSee Remarks | Mar 19 | Mar 23 | A · derivative | 50,150 | $3.91 | $196,087 | 50,150 | No | Form 4 |
| Eizen Joshua MSee Remarks | Mar 19 | Mar 23 | D · derivative | 50,150 | $14.29 | $716,644 | not reported | No | Form 4 |
| Zakrzewski Joseph S | Mar 19 | Mar 23 | A · derivative | 99,999 | $3.91 | $390,996 | 99,999 | No | Form 4 |
| Zakrzewski Joseph S | Mar 19 | Mar 23 | D · derivative | 99,999 | $6.60 | $659,993 | not reported | No | Form 4 |
| Zakrzewski Joseph S | Mar 19 | Mar 23 | A · derivative | 10,362 | $3.91 | $40,515 | 10,362 | No | Form 4 |
| Zakrzewski Joseph S | Mar 19 | Mar 23 | D · derivative | 10,362 | $17.28 | $179,055 | not reported | No | Form 4 |
| Zakrzewski Joseph S | Mar 19 | Mar 23 | A · derivative | 23,742 | $3.91 | $92,831 | 23,742 | No | Form 4 |
| Zakrzewski Joseph S | Mar 19 | Mar 23 | D · derivative | 23,742 | $5.91 | $140,315 | not reported | No | Form 4 |
| Wong Stephanie | Mar 19 | Mar 23 | A · derivative | 24,999 | $3.91 | $97,746 | 24,999 | No | Form 4 |
| Wong Stephanie | Mar 19 | Mar 23 | D · derivative | 24,999 | $6.60 | $164,993 | not reported | No | Form 4 |
| Wong Stephanie | Mar 19 | Mar 23 | A · derivative | 10,362 | $3.91 | $40,515 | 10,362 | No | Form 4 |
| Wong Stephanie | Mar 19 | Mar 23 | D · derivative | 10,362 | $17.28 | $179,055 | not reported | No | Form 4 |
| Wong Stephanie | Mar 19 | Mar 23 | A · derivative | 23,742 | $3.91 | $92,831 | 23,742 | No | Form 4 |
| Wong Stephanie | Mar 19 | Mar 23 | D · derivative | 23,742 | $5.91 | $140,315 | not reported | No | Form 4 |
| FitzPatrick Margaret M | Mar 19 | Mar 23 | A · derivative | 11,463 | $3.91 | $44,820 | 11,463 | No | Form 4 |
| FitzPatrick Margaret M | Mar 19 | Mar 23 | D · derivative | 11,463 | $18.24 | $209,085 | not reported | No | Form 4 |
| FitzPatrick Margaret M | Mar 19 | Mar 23 | A · derivative | 10,362 | $3.91 | $40,515 | 10,362 | No | Form 4 |
| FitzPatrick Margaret M | Mar 19 | Mar 23 | D · derivative | 10,362 | $17.28 | $179,055 | not reported | No | Form 4 |
| FitzPatrick Margaret M | Mar 19 | Mar 23 | A · derivative | 23,742 | $3.91 | $92,831 | 23,742 | No | Form 4 |
| FitzPatrick Margaret M | Mar 19 | Mar 23 | D · derivative | 23,742 | $5.91 | $140,315 | not reported | No | Form 4 |
| Martin Patricia A. | Mar 19 | Mar 23 | A · derivative | 24,999 | $3.91 | $97,746 | 24,999 | No | Form 4 |
| Martin Patricia A. | Mar 19 | Mar 23 | D · derivative | 24,999 | $6.60 | $164,993 | not reported | No | Form 4 |
| Martin Patricia A. | Mar 19 | Mar 23 | A · derivative | 10,362 | $3.91 | $40,515 | 10,362 | No | Form 4 |
| Martin Patricia A. | Mar 19 | Mar 23 | D · derivative | 10,362 | $17.28 | $179,055 | not reported | No | Form 4 |
| Martin Patricia A. | Mar 19 | Mar 23 | A · derivative | 23,742 | $3.91 | $92,831 | 23,742 | No | Form 4 |
| Martin Patricia A. | Mar 19 | Mar 23 | D · derivative | 23,742 | $5.91 | $140,315 | not reported | No | Form 4 |
| Aziz Kabeer | Mar 19 | Mar 23 | A · derivative | 20,724 | $3.91 | $81,031 | 20,724 | No | Form 4 |
| Aziz Kabeer | Mar 19 | Mar 23 | D · derivative | 20,724 | $17.28 | $358,111 | not reported | No | Form 4 |
| Aziz Kabeer | Mar 19 | Mar 23 | A · derivative | 23,742 | $3.91 | $92,831 | 23,742 | No | Form 4 |
| Aziz Kabeer | Mar 19 | Mar 23 | D · derivative | 23,742 | $5.91 | $140,315 | not reported | No | Form 4 |
| Marks Gilbert Lynn | Mar 19 | Mar 23 | A · derivative | 10,665 | $3.91 | $41,700 | 10,665 | No | Form 4 |
| Marks Gilbert Lynn | Mar 19 | Mar 23 | D · derivative | 10,665 | $6.60 | $70,389 | not reported | No | Form 4 |
| Marks Gilbert Lynn | Mar 19 | Mar 23 | A · derivative | 10,362 | $3.91 | $40,515 | 10,362 | No | Form 4 |
| Marks Gilbert Lynn | Mar 19 | Mar 23 | D · derivative | 10,362 | $17.28 | $179,055 | not reported | No | Form 4 |
| Marks Gilbert Lynn | Mar 19 | Mar 23 | A · derivative | 23,742 | $3.91 | $92,831 | 23,742 | No | Form 4 |
| Marks Gilbert Lynn | Mar 19 | Mar 23 | D · derivative | 23,742 | $5.91 | $140,315 | not reported | No | Form 4 |
| Chanda SanjayChief Development Officer | Mar 19 | Mar 23 | A · derivative | 66,000 | $3.91 | $258,060 | 66,000 | No | Form 4 |
| Chanda SanjayChief Development Officer | Mar 19 | Mar 23 | D · derivative | 66,000 | $17.28 | $1,140,480 | not reported | No | Form 4 |
| Chanda SanjayChief Development Officer | Mar 19 | Mar 23 | A · derivative | 57,950 | $3.91 | $226,585 | 57,950 | No | Form 4 |
| Chanda SanjayChief Development Officer | Mar 19 | Mar 23 | D · derivative | 57,950 | $14.29 | $828,106 | not reported | No | Form 4 |
| Chanda SanjayChief Development Officer | Mar 19 | Mar 23 | A · derivative | 41,665 | $3.91 | $162,910 | 41,665 | No | Form 4 |
| Chanda SanjayChief Development Officer | Mar 19 | Mar 23 | D · derivative | 41,665 | $6.60 | $274,989 | not reported | No | Form 4 |
| Day LucyChief Financial Officer | Mar 19 | Mar 23 | A · derivative | 73,665 | $3.91 | $288,030 | 73,665 | No | Form 4 |
| Day LucyChief Financial Officer | Mar 19 | Mar 23 | D · derivative | 73,665 | $6.60 | $486,189 | not reported | No | Form 4 |
| Day LucyChief Financial Officer | Mar 19 | Mar 23 | A · derivative | 66,000 | $3.91 | $258,060 | 66,000 | No | Form 4 |
| Day LucyChief Financial Officer | Mar 19 | Mar 23 | D · derivative | 66,000 | $17.28 | $1,140,480 | not reported | No | Form 4 |
| Day LucyChief Financial Officer | Mar 19 | Mar 23 | A · derivative | 82,300 | $3.91 | $321,793 | 82,300 | No | Form 4 |
| Day LucyChief Financial Officer | Mar 19 | Mar 23 | D · derivative | 82,300 | $14.29 | $1,176,067 | not reported | No | Form 4 |
| Williams Sarah JoannePrincipal Accounting Officer | Mar 3 | Mar 5 | S | 327 | $1.06 | Sale −$347 | 66,848 | No | Form 4 |
| Zakrzewski Joseph S | Feb 20 | Feb 23 | A · derivative | 20,400 | $1.04 | $21,216 | 20,400 | No | Form 4 |
| FitzPatrick Margaret M | Feb 20 | Feb 23 | A · derivative | 20,400 | $1.04 | $21,216 | 20,400 | No | Form 4 |
| Aziz Kabeer | Feb 20 | Feb 23 | A · derivative | 20,400 | $1.04 | $21,216 | 20,400 | No | Form 4 |
| Spigelman Melvin K | Feb 20 | Feb 23 | A · derivative | 20,400 | $1.04 | $21,216 | 20,400 | No | Form 4 |
| Martin Patricia A. | Feb 20 | Feb 23 | A · derivative | 20,400 | $1.04 | $21,216 | 20,400 | No | Form 4 |
| Wong Stephanie | Feb 20 | Feb 23 | A · derivative | 20,400 | $1.04 | $21,216 | 20,400 | No | Form 4 |
| Readnour Robin Shane | Feb 20 | Feb 23 | A · derivative | 20,400 | $1.04 | $21,216 | 20,400 | No | Form 4 |
| Marks Gilbert Lynn | Feb 20 | Feb 23 | A · derivative | 20,400 | $1.04 | $21,216 | 20,400 | No | Form 4 |
| Chanda SanjayChief Development Officer | Feb 20 | Feb 23 | A | 38,000 | $0.00 | $0 | 118,823 | No | Form 4 |
| Chanda SanjayChief Development Officer | Feb 20 | Feb 23 | A · derivative | 77,000 | $1.04 | $80,080 | 77,000 | No | Form 4 |
| Easom EricChief Executive Officer | Feb 20 | Feb 23 | A | 112,250 | $0.00 | $0 | 368,630 | No | Form 4 |
| Easom EricChief Executive Officer | Feb 20 | Feb 23 | A · derivative | 224,500 | $1.04 | $233,480 | 224,500 | No | Form 4 |
| Williams Sarah JoannePrincipal Accounting Officer | Feb 20 | Feb 23 | A | 48,375 | $0.00 | $0 | 67,175 | No | Form 4 |
| Day LucyChief Financial Officer | Feb 20 | Feb 23 | A | 38,000 | $0.00 | $0 | 118,363 | No | Form 4 |
| Day LucyChief Financial Officer | Feb 20 | Feb 23 | A · derivative | 77,000 | $1.04 | $80,080 | 77,000 | No | Form 4 |
| Eizen Joshua MSee Remarks | Feb 20 | Feb 23 | A | 50,000 | $0.00 | $0 | 207,499 | No | Form 4 |
| Eizen Joshua MSee Remarks | Feb 20 | Feb 23 | A · derivative | 100,000 | $1.04 | $104,000 | 100,000 | No | Form 4 |
| Marks Gilbert Lynn | Jan 12 | Jan 14 | A | 11,560 | $0.00 | $0 | 75,309 | No | Form 4 |
| Martin Patricia A. | Jan 12 | Jan 14 | A | 3,650 | $0.00 | $0 | 16,905 | No | Form 4 |
| Aziz Kabeer | Jan 12 | Jan 14 | A | 11,560 | $0.00 | $0 | 52,479 | No | Form 4 |
| Eizen Joshua MSee Remarks | Jan 6 | Jan 7 | S | 6,931 | $1.01 | Sale −$7,000 | 152,499 | No | Form 4 |
| Chanda SanjayChief Development Officer | Jan 6 | Jan 7 | S | 5,956 | $1.01 | Sale −$6,016 | 75,823 | No | Form 4 |
| Prior Stephen DavidChief Strategy Officer | Jan 6 | Jan 7 | S | 2,858 | $1.01 | Sale −$2,887 | 59,086 | No | Form 4 |
| Day LucyChief Financial Officer | Jan 6 | Jan 7 | S | 5,512 | $1.01 | Sale −$5,567 | 75,363 | No | Form 4 |
| Eizen Joshua MSee Remarks | Jan 5 | Jan 7 | S | 17,923 | $1.00 | Sale −$17,923 | 159,430 | No | Form 4 |
| Chanda SanjayChief Development Officer | Jan 5 | Jan 7 | S | 3,295 | $1.00 | Sale −$3,295 | 81,779 | No | Form 4 |
| Prior Stephen DavidChief Strategy Officer | Jan 5 | Jan 7 | S | 3,604 | $1.00 | Sale −$3,604 | 61,944 | No | Form 4 |
| Day LucyChief Financial Officer | Jan 5 | Jan 7 | S | 3,295 | $1.00 | Sale −$3,295 | 80,875 | No | Form 4 |
| Prior Stephen DavidChief Strategy Officer | Nov 4, 2025 | Nov 6, 2025 | S | 765 | $1.14 | Sale −$872 | 65,548 | No | Form 4 |
| Eizen Joshua MSee Remarks | Nov 4, 2025 | Nov 6, 2025 | S | 2,819 | $1.14 | Sale −$3,214 | 177,353 | No | Form 4 |
| Martin Patricia A. | Oct 10, 2025 | Oct 14, 2025 | A | 3,274 | $0.00 | $0 | 13,255 | No | Form 4 |
| Aziz Kabeer | Oct 10, 2025 | Oct 14, 2025 | A | 10,367 | $0.00 | $0 | 40,919 | No | Form 4 |
| Marks Gilbert Lynn | Oct 10, 2025 | Oct 14, 2025 | A | 10,367 | $0.00 | $0 | 63,749 | No | Form 4 |
| Martin Patricia A. | Jul 10, 2025 | Jul 11, 2025 | A | 3,750 | $0.00 | $0 | 9,981 | No | Form 4 |
| Marks Gilbert Lynn | Jul 10, 2025 | Jul 11, 2025 | A | 11,875 | $0.00 | $0 | 53,382 | No | Form 4 |
| Aziz Kabeer | Jul 10, 2025 | Jul 11, 2025 | A | 11,875 | $0.00 | $0 | 30,552 | No | Form 4 |
| Leonard Braden Michael | May 28, 2025 | Jun 16, 2025 | S | 200,000 | $1.09 | Sale −$218,000 | 3,017,432 | No | Form 4 |
| Easom EricChief Executive Officer | Jun 2, 2025 | Jun 3, 2025 | P | 10,000 | $1.07 | Purchase +$10,700 | 256,380 | No | Form 4 |
| Leonard Braden Michael | May 30, 2025 | May 30, 2025 | S | 425,000 | $1.01 | Sale −$429,250 | 3,224,432 | No | Form 4 |
| Leonard Braden Michael | May 30, 2025 | May 30, 2025 | S | 7,000 | $1.03 | Sale −$7,210 | 3,217,432 | No | Form 4 |
| Leonard Braden Michael | May 28, 2025 | May 30, 2025 | S | 2,000,000 | $1.16 | Sale −$2,320,000 | 3,749,432 | No | Form 4 |
| Leonard Braden Michael | May 28, 2025 | May 30, 2025 | S | 100,000 | $1.16 | Sale −$116,000 | 3,649,432 | No | Form 4 |
| FitzPatrick Margaret M | May 28, 2025 | May 29, 2025 | P | 8,610 | $1.18 | Purchase +$10,160 | 8,610 | No | Form 4 |
| Aziz Kabeer | May 22, 2025 | May 23, 2025 | A · derivative | 19,111 | $1.19 | $22,742 | 19,111 | No | Form 4 |
| Marks Gilbert Lynn | May 22, 2025 | May 23, 2025 | A · derivative | 19,111 | $1.19 | $22,742 | 19,111 | No | Form 4 |
| Wong Stephanie | May 22, 2025 | May 23, 2025 | A · derivative | 19,111 | $1.19 | $22,742 | 19,111 | No | Form 4 |
| Spigelman Melvin K | May 22, 2025 | May 23, 2025 | A · derivative | 19,111 | $1.19 | $22,742 | 19,111 | No | Form 4 |
| Zakrzewski Joseph S | May 22, 2025 | May 23, 2025 | A · derivative | 19,111 | $1.19 | $22,742 | 19,111 | No | Form 4 |
| FitzPatrick Margaret M | May 22, 2025 | May 23, 2025 | A · derivative | 19,111 | $1.19 | $22,742 | 19,111 | No | Form 4 |
| Martin Patricia A. | May 22, 2025 | May 23, 2025 | A · derivative | 19,111 | $1.19 | $22,742 | 19,111 | No | Form 4 |
| Readnour Robin Shane | May 22, 2025 | May 23, 2025 | A · derivative | 19,111 | $1.19 | $22,742 | 19,111 | No | Form 4 |
| Marks Gilbert Lynn | Apr 10, 2025 | Apr 11, 2025 | A | 9,705 | $0.00 | $0 | 41,507 | No | Form 4 |
| Martin Patricia A. | Apr 10, 2025 | Apr 11, 2025 | A | 3,065 | $0.00 | $0 | 6,231 | No | Form 4 |
| Aziz Kabeer | Apr 10, 2025 | Apr 11, 2025 | A | 9,705 | $0.00 | $0 | 18,677 | No | Form 4 |
| Zakrzewski Joseph S | Apr 10, 2025 | Apr 11, 2025 | A | 10,523 | $0.00 | $0 | 145,538 | No | Form 4 |
| Prior Stephen DavidChief Strategy Officer | Feb 26, 2025 | Feb 28, 2025 | A | 28,000 | $0.00 | $0 | 61,313 | No | Form 4 |
| Prior Stephen DavidChief Strategy Officer | Feb 26, 2025 | Feb 28, 2025 | A · derivative | 56,000 | $1.13 | $63,280 | 56,000 | No | Form 4 |
| Easom EricChief Executive Officer | Feb 26, 2025 | Feb 28, 2025 | A | 145,250 | $0.00 | $0 | 246,380 | No | Form 4 |
| Easom EricChief Executive Officer | Feb 26, 2025 | Feb 28, 2025 | A · derivative | 290,500 | $1.13 | $328,265 | 290,500 | No | Form 4 |
| Eizen Joshua MSee Remarks | Feb 26, 2025 | Feb 28, 2025 | A | 58,500 | $0.00 | $0 | 175,172 | No | Form 4 |
| Eizen Joshua MSee Remarks | Feb 26, 2025 | Feb 28, 2025 | A · derivative | 117,000 | $1.13 | $132,210 | 117,000 | No | Form 4 |
| Day LucyChief Financial Officer | Feb 26, 2025 | Feb 28, 2025 | A | 46,500 | $0.00 | $0 | 79,170 | No | Form 4 |
| Day LucyChief Financial Officer | Feb 26, 2025 | Feb 28, 2025 | A · derivative | 93,000 | $1.13 | $105,090 | 93,000 | No | Form 4 |
| Chanda SanjayChief Development Officer | Feb 26, 2025 | Feb 28, 2025 | A | 50,250 | $0.00 | $0 | 80,074 | No | Form 4 |
| Chanda SanjayChief Development Officer | Feb 26, 2025 | Feb 28, 2025 | A · derivative | 100,500 | $1.13 | $113,565 | 100,500 | No | Form 4 |
| Eizen Joshua MSee Remarks | Jan 3, 2025 | Jan 7, 2025 | S | 9,663 | $1.34 | Sale −$12,948 | 116,672 | No | Form 4 |
| Prior Stephen DavidChief Strategy Officer | Jan 3, 2025 | Jan 7, 2025 | S | 2,029 | $1.34 | Sale −$2,719 | 33,313 | No | Form 4 |
| Chanda SanjayChief Development Officer | Jan 3, 2025 | Jan 7, 2025 | S | 2,957 | $1.34 | Sale −$3,962 | 29,824 | No | Form 4 |
| Day LucyChief Financial Officer | Jan 3, 2025 | Jan 7, 2025 | S | 2,957 | $1.34 | Sale −$3,962 | 32,670 | No | Form 4 |
| Readnour Robin Shane | Dec 19, 2024 | Dec 23, 2024 | A | 9,077 | $0.00 | $0 | 9,077 | No | Form 4 |
| Zakrzewski Joseph S | Dec 19, 2024 | Dec 23, 2024 | A | 9,816 | $0.00 | $0 | 135,015 | No | Form 4 |
| Marks Gilbert Lynn | Dec 19, 2024 | Dec 23, 2024 | A | 8,972 | $0.00 | $0 | 31,802 | No | Form 4 |
| Aziz Kabeer | Dec 19, 2024 | Dec 23, 2024 | A | 8,972 | $0.00 | $0 | 8,972 | No | Form 4 |
| Martin Patricia A. | Dec 19, 2024 | Dec 23, 2024 | A | 3,166 | $0.00 | $0 | 3,166 | No | Form 4 |
| Readnour Robin Shane | Dec 10, 2024 | Dec 10, 2024 | P | 5,000 | $1.49 | Purchase +$7,450 | 582,288 | No | Form 4 |
| Readnour Robin Shane | Dec 10, 2024 | Dec 10, 2024 | P | 5,000 | $1.49 | Purchase +$7,450 | 652,573 | No | Form 4 |
| Readnour Robin Shane | Dec 9, 2024 | Dec 10, 2024 | P | 12,289 | $1.43 | Purchase +$17,573 | 577,288 | No | Form 4 |
| Readnour Robin Shane | Dec 9, 2024 | Dec 10, 2024 | P | 18,483 | $1.43 | Purchase +$26,431 | 647,573 | No | Form 4 |
| Readnour Robin Shane | Dec 6, 2024 | Dec 10, 2024 | P | 12,711 | $1.45 | Purchase +$18,431 | 564,999 | No | Form 4 |
| Readnour Robin Shane | Dec 6, 2024 | Dec 10, 2024 | P | 6,517 | $1.45 | Purchase +$9,450 | 629,090 | No | Form 4 |
| Zakrzewski Joseph S | Nov 27, 2024 | Nov 27, 2024 | P | 2,000 | $1.40 | Purchase +$2,800 | 125,199 | No | Form 4 |
| Readnour Robin Shane | Nov 27, 2024 | Nov 27, 2024 | P | 25,000 | $1.42 | Purchase +$35,500 | 552,288 | No | Form 4 |
| Readnour Robin Shane | Nov 27, 2024 | Nov 27, 2024 | P | 25,000 | $1.42 | Purchase +$35,500 | 622,573 | No | Form 4 |
| Readnour Robin Shane | Nov 26, 2024 | Nov 27, 2024 | P | 12,500 | $1.39 | Purchase +$17,375 | 527,288 | No | Form 4 |
| Readnour Robin Shane | Nov 26, 2024 | Nov 27, 2024 | P | 12,500 | $1.39 | Purchase +$17,375 | 597,573 | No | Form 4 |
| Readnour Robin Shane | Nov 20, 2024 | Nov 21, 2024 | P | 25,000 | $1.16 | Purchase +$29,000 | 585,073 | No | Form 4 |
| Readnour Robin Shane | Nov 20, 2024 | Nov 21, 2024 | P | 25,000 | $1.15 | Purchase +$28,750 | 514,788 | No | Form 4 |
| Readnour Robin Shane | Nov 19, 2024 | Nov 21, 2024 | P | 75,000 | $1.03 | Purchase +$77,250 | 560,073 | No | Form 4 |
| Readnour Robin Shane | Nov 19, 2024 | Nov 21, 2024 | P | 75,000 | $1.04 | Purchase +$78,000 | 489,788 | No | Form 4 |
| Zakrzewski Joseph S | Nov 19, 2024 | Nov 20, 2024 | P | 5,000 | $1.01 | Purchase +$5,050 | 123,199 | No | Form 4 |
| Zakrzewski Joseph S | Nov 18, 2024 | Nov 20, 2024 | P | 20,000 | $1.00 | Purchase +$20,000 | 118,199 | No | Form 4 |
| Easom EricChief Executive Officer | Nov 18, 2024 | Nov 18, 2024 | P | 50,000 | $1.00 | Purchase +$50,000 | 1,065,766 | No | Form 4 |
| Eizen Joshua MSee Remarks | Nov 4, 2024 | Nov 5, 2024 | A | 31,500 | $0.00 | $0 | 126,335 | No | Form 4 |
| Eizen Joshua MSee Remarks | Nov 4, 2024 | Nov 5, 2024 | A · derivative | 63,000 | $1.08 | $68,040 | 63,000 | No | Form 4 |
| Prior Stephen DavidChief Strategy Officer | Nov 4, 2024 | Nov 5, 2024 | A | 10,125 | $0.00 | $0 | 35,342 | No | Form 4 |
| Prior Stephen DavidChief Strategy Officer | Nov 4, 2024 | Nov 5, 2024 | A · derivative | 20,250 | $1.08 | $21,870 | 20,250 | No | Form 4 |
| Leonard Braden Michael | Aug 14, 2024 | Aug 14, 2024 | P | 1,500,000 | $1.04 | Purchase +$1,560,000 | 5,749,432 | No | Form 4 |
| RA Capital Healthcare Fund LP | Aug 9, 2024 | Aug 13, 2024 | S | 3,410,335 | $1.08 | Sale −$3,683,162 | 1,725,348 | No | Form 4 |
| RA Capital Healthcare Fund LP | Aug 9, 2024 | Aug 13, 2024 | S | 114,759 | $1.08 | Sale −$123,940 | 300,853 | No | Form 4 |
| Eizen Joshua MChief Legal Officer | Jul 10, 2024 | Jul 12, 2024 | A | 60,000 | $0.00 | $0 | 94,833 | No | Form 4 |
| Wong Stephanie | Jun 19, 2024 | Jun 21, 2024 | A · derivative | 64,503 | $2.00 | $129,006 | 64,503 | No | Form 4 |
| Martin Patricia A. | Jun 19, 2024 | Jun 21, 2024 | A · derivative | 64,503 | $2.00 | $129,006 | 64,503 | No | Form 4 |
| Spigelman Melvin K | Jun 19, 2024 | Jun 21, 2024 | A · derivative | 64,503 | $2.00 | $129,006 | 64,503 | No | Form 4 |
| Zakrzewski Joseph S | Jun 19, 2024 | Jun 21, 2024 | A · derivative | 64,503 | $2.00 | $129,006 | 64,503 | No | Form 4 |
| Aziz Kabeer | Jun 19, 2024 | Jun 21, 2024 | A · derivative | 64,503 | $2.00 | $129,006 | 64,503 | No | Form 4 |
| FitzPatrick Margaret M | Jun 19, 2024 | Jun 21, 2024 | A · derivative | 64,503 | $2.00 | $129,006 | 64,503 | No | Form 4 |
| Marks Gilbert Lynn | Jun 19, 2024 | Jun 21, 2024 | A · derivative | 64,503 | $2.00 | $129,006 | 64,503 | No | Form 4 |
| Readnour Robin Shane | Jun 19, 2024 | Jun 21, 2024 | A · derivative | 64,503 | $2.00 | $129,006 | 64,503 | No | Form 4 |
| Easom EricChief Executive Officer | Mar 15, 2024 | Mar 29, 20244/A | A | 99,000 | $0.00 | $0 | 101,130 | No | Form 4/A |
| Chanda SanjayChief Development Officer | Mar 15, 2024 | Mar 29, 20244/A | A | 27,500 | $0.00 | $0 | 28,235 | No | Form 4/A |
| Krause Kevin MichaelChief Strategy Officer | Mar 15, 2024 | Mar 29, 20244/A | A | 30,000 | $0.00 | $0 | 31,914 | No | Form 4/A |
| Eizen Joshua MChief Legal Officer | Mar 15, 2024 | Mar 29, 20244/A | A | 30,000 | $0.00 | $0 | 32,447 | No | Form 4/A |
| Day LucyChief Financial Officer | Mar 15, 2024 | Mar 29, 20244/A | A | 27,500 | $0.00 | $0 | 30,627 | No | Form 4/A |
| Eckburg PaulChief Medical Officer | Mar 15, 2024 | Mar 29, 20244/A | A | 30,000 | $0.00 | $0 | 51,416 | No | Form 4/A |
| Zakrzewski Joseph S | Jan 18, 2024 | Jan 19, 2024 | S | 100,000 | $19.11 | Sale −$1,911,000 | 405,880 | No | Form 4 |
| Adjuvant Capital Management, LLC | Jan 16, 2024 | Jan 18, 2024 | S | 84,093 | $19.65 | Sale −$1,652,427 | 1,995,958 | No | Form 4 |
| Adjuvant Capital Management, LLC | Jan 16, 2024 | Jan 18, 2024 | S | 15,907 | $19.65 | Sale −$312,573 | 377,542 | No | Form 4 |
| Aziz Kabeer | Jan 16, 2024 | Jan 18, 2024 | S | 84,093 | $19.65 | Sale −$1,652,427 | 1,995,958 | No | Form 4 |
| Aziz Kabeer | Jan 16, 2024 | Jan 18, 2024 | S | 15,907 | $19.65 | Sale −$312,573 | 377,542 | No | Form 4 |
| Readnour Robin Shane | Jan 12, 2024 | Jan 17, 2024 | S | 706 | $21.92 | Sale −$15,476 | 414,788 | Yes | Form 4 |
| Readnour Robin Shane | Jan 12, 2024 | Jan 17, 2024 | S | 719 | $21.91 | Sale −$15,753 | 485,073 | Yes | Form 4 |
| Readnour Robin Shane | Jan 10, 2024 | Jan 12, 2024 | S | 1,869 | $21.93 | Sale −$40,987 | 415,494 | Yes | Form 4 |
| Readnour Robin Shane | Jan 10, 2024 | Jan 12, 2024 | S | 1,800 | $21.92 | Sale −$39,456 | 485,792 | Yes | Form 4 |
| Krause Kevin MichaelChief Strategy Officer | Jan 9, 2024 | Jan 11, 2024 | M | 2,417 | $0.42 | $1,015 | 4,331 | Yes | Form 4 |
| Krause Kevin MichaelChief Strategy Officer | Jan 9, 2024 | Jan 11, 2024 | M | 5,000 | $6.60 | $33,000 | 9,331 | Yes | Form 4 |
| Krause Kevin MichaelChief Strategy Officer | Jan 9, 2024 | Jan 11, 2024 | S | 7,417 | $20.14 | Sale −$149,378 | 1,914 | Yes | Form 4 |
| Krause Kevin MichaelChief Strategy Officer | Jan 9, 2024 | Jan 11, 2024 | M · derivative | 2,417 | $0.42 | $1,015 | 49,868 | Yes | Form 4 |
| Krause Kevin MichaelChief Strategy Officer | Jan 9, 2024 | Jan 11, 2024 | M · derivative | 5,000 | $6.60 | $33,000 | 26,832 | Yes | Form 4 |
| Easom EricChief Executive Officer | Jan 2, 2024 | Jan 4, 2024 | S | 2,777 | $20.09 | Sale −$55,790 | 2,130 | Yes | Form 4 |
| Krause Kevin MichaelChief Strategy Officer | Jan 2, 2024 | Jan 4, 2024 | M | 2,583 | $0.42 | $1,085 | 4,497 | Yes | Form 4 |
| Krause Kevin MichaelChief Strategy Officer | Jan 2, 2024 | Jan 4, 2024 | S | 2,583 | $20.12 | Sale −$51,970 | 1,914 | Yes | Form 4 |
| Krause Kevin MichaelChief Strategy Officer | Jan 2, 2024 | Jan 4, 2024 | M · derivative | 2,583 | $0.42 | $1,085 | 52,285 | Yes | Form 4 |
| Aziz Kabeer | Nov 14, 2023 | Nov 16, 2023 | S | 1,522 | $16.15 | Sale −$24,580 | 2,080,051 | Yes | Form 4 |
| Aziz Kabeer | Nov 14, 2023 | Nov 16, 2023 | S | 288 | $16.15 | Sale −$4,651 | 393,449 | Yes | Form 4 |
| Adjuvant Capital Management, LLC | Nov 14, 2023 | Nov 16, 2023 | S | 1,522 | $16.15 | Sale −$24,580 | 2,080,051 | Yes | Form 4 |
| Adjuvant Capital Management, LLC | Nov 14, 2023 | Nov 16, 2023 | S | 288 | $16.15 | Sale −$4,651 | 393,449 | Yes | Form 4 |
| Adjuvant Global Health Technology Fund, L.P. | Oct 2, 2023 | Oct 3, 2023 | S | 4,770 | $16.07 | Sale −$76,654 | 2,081,573 | No | Form 4 |
| Adjuvant Global Health Technology Fund, L.P. | Oct 2, 2023 | Oct 3, 2023 | S | 902 | $16.07 | Sale −$14,495 | 393,737 | No | Form 4 |
| Aziz Kabeer | Oct 2, 2023 | Oct 3, 2023 | S | 4,770 | $16.07 | Sale −$76,654 | 2,081,573 | No | Form 4 |
| Aziz Kabeer | Oct 2, 2023 | Oct 3, 2023 | S | 902 | $16.07 | Sale −$14,495 | 393,737 | No | Form 4 |
| Adjuvant Global Health Technology Fund, L.P. | Sep 29, 2023 | Oct 3, 2023 | S | 83,337 | $16.28 | Sale −$1,356,726 | 2,086,343 | No | Form 4 |
| Adjuvant Global Health Technology Fund, L.P. | Sep 29, 2023 | Oct 3, 2023 | S | 15,764 | $16.28 | Sale −$256,638 | 394,639 | No | Form 4 |
| Aziz Kabeer | Sep 29, 2023 | Oct 3, 2023 | S | 83,337 | $16.28 | Sale −$1,356,726 | 2,086,343 | No | Form 4 |
| Aziz Kabeer | Sep 29, 2023 | Oct 3, 2023 | S | 15,764 | $16.28 | Sale −$256,638 | 394,639 | No | Form 4 |