ARDXARDELYX, INC.
- Market cap
- $795.22M
- as of 2026-10-23
- Latest close
- $3.08
- as of 2026-10-23
- Sector
- Healthcare
- as of 2026-10-24
- Industry
- Biotechnology
- as of 2026-10-24
Cluster
No cluster in the last 90 days under the default rule (14d · ≥2 insiders · all roles).
Form 4 historysince 2023-10-12
| Insider | Traded | Filed | Type | Shares | Price | Value | Owned after | 10b5-1 plan | Filing |
|---|---|---|---|---|---|---|---|---|---|
| Bishop John ESee Remarks | Aug 21 | Aug 25 | S | 17,281 | $3.86 | Sale −$66,705 | 319,564 | No | Form 4 |
| Bishop John ESee Remarks | Aug 21 | Aug 25 | S | 2,469 | $3.86 | Sale −$9,530 | 317,095 | No | Form 4 |
| Raab MichaelPresident & CEO | Aug 21 | Aug 25 | S | 15,009 | $3.86 | Sale −$57,935 | 1,663,357 | No | Form 4 |
| Raab MichaelPresident & CEO | Aug 21 | Aug 25 | S | 15,976 | $3.86 | Sale −$61,667 | 1,647,381 | No | Form 4 |
| Raab MichaelPresident & CEO | Aug 21 | Aug 25 | S | 8,411 | $3.86 | Sale −$32,466 | 1,638,970 | No | Form 4 |
| Raab MichaelPresident & CEO | Aug 21 | Aug 25 | S | 19,178 | $3.86 | Sale −$74,027 | 1,619,792 | No | Form 4 |
| Williams Laura AChief Patient Officer | Aug 21 | Aug 25 | S | 3,486 | $3.86 | Sale −$13,456 | 374,709 | No | Form 4 |
| Williams Laura AChief Patient Officer | Aug 21 | Aug 25 | S | 3,089 | $3.86 | Sale −$11,924 | 371,620 | No | Form 4 |
| Williams Laura AChief Patient Officer | Aug 21 | Aug 25 | S | 2,430 | $3.86 | Sale −$9,380 | 369,190 | No | Form 4 |
| Williams Laura AChief Patient Officer | Aug 21 | Aug 25 | S | 1,734 | $3.86 | Sale −$6,693 | 367,456 | No | Form 4 |
| Kelliher MikeChief Business Officer | Aug 21 | Aug 25 | S | 3,104 | $3.86 | Sale −$11,981 | 354,314 | No | Form 4 |
| Kelliher MikeChief Business Officer | Aug 21 | Aug 25 | S | 2,652 | $3.86 | Sale −$10,237 | 351,662 | No | Form 4 |
| Kelliher MikeChief Business Officer | Aug 21 | Aug 25 | S | 2,002 | $3.86 | Sale −$7,728 | 349,660 | No | Form 4 |
| Foster Eric DuaneChief Commercial Officer | Aug 21 | Aug 25 | S | 2,598 | $3.86 | Sale −$10,028 | 415,374 | No | Form 4 |
| Foster Eric DuaneChief Commercial Officer | Aug 21 | Aug 25 | S | 3,389 | $3.86 | Sale −$13,082 | 411,985 | No | Form 4 |
| Foster Eric DuaneChief Commercial Officer | Aug 21 | Aug 25 | S | 2,575 | $3.86 | Sale −$9,940 | 409,410 | No | Form 4 |
| Reilly Joseph JamesSee Remarks | Aug 21 | Aug 25 | S | 2,872 | $3.86 | Sale −$11,086 | 146,964 | No | Form 4 |
| Reilly Joseph JamesSee Remarks | Aug 21 | Aug 25 | S | 1,110 | $3.86 | Sale −$4,285 | 145,854 | No | Form 4 |
| Brady James ParkerChief Human Resources Officer | Aug 21 | Aug 25 | S | 1,976 | $3.86 | Sale −$7,627 | 259,090 | No | Form 4 |
| Brady James ParkerChief Human Resources Officer | Aug 21 | Aug 25 | S | 13,160 | $3.86 | Sale −$50,798 | 245,930 | No | Form 4 |
| Hohenleitner SusanChief Financial Officer | Aug 21 | Aug 25 | S | 1,558 | $3.86 | Sale −$6,014 | 227,520 | No | Form 4 |
| Raab MichaelPresident & CEO | Jul 15 | Jul 17 | M | 20,834 | $0.99 | $20,626 | 1,720,034 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Jul 15 | Jul 17 | S | 41,668 | $5.06 | Sale −$210,840 | 1,678,366 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Jul 15 | Jul 17 | M · derivative | 20,834 | $0.99 | $20,626 | 290,834 | Yes | Form 4 |
| Williams Laura AChief Patient Officer | Jun 18 | Jun 22 | M | 31,000 | $0.99 | $30,690 | 460,093 | Yes | Form 4 |
| Williams Laura AChief Patient Officer | Jun 18 | Jun 22 | S | 81,898 | $5.99 | Sale −$490,569 | 378,195 | Yes | Form 4 |
| Williams Laura AChief Patient Officer | Jun 18 | Jun 22 | M · derivative | 31,000 | $0.99 | $30,690 | 31,000 | Yes | Form 4 |
| Mott David M | Jun 16 | Jun 18 | A | 20,282 | $0.00 | $0 | 3,323,200 | No | Form 4 |
| Mott David M | Jun 16 | Jun 18 | A | 26,455 | $0.00 | $0 | 3,349,655 | No | Form 4 |
| Mott David M | Jun 16 | Jun 18 | A · derivative | 39,715 | $5.67 | $225,184 | 39,715 | No | Form 4 |
| Bertrand William C JR | Jun 16 | Jun 18 | A | 12,345 | $0.00 | $0 | 303,052 | No | Form 4 |
| Bertrand William C JR | Jun 16 | Jun 18 | A | 26,455 | $0.00 | $0 | 329,507 | No | Form 4 |
| Bertrand William C JR | Jun 16 | Jun 18 | A · derivative | 39,715 | $5.67 | $225,184 | 39,715 | No | Form 4 |
| Rodgers Richard J | Jun 16 | Jun 18 | A | 26,455 | $0.00 | $0 | 439,998 | No | Form 4 |
| Rodgers Richard J | Jun 16 | Jun 18 | A · derivative | 39,715 | $5.67 | $225,184 | 39,715 | No | Form 4 |
| Bazemore Robert B | Jun 16 | Jun 18 | A | 26,455 | $0.00 | $0 | 68,006 | No | Form 4 |
| Bazemore Robert B | Jun 16 | Jun 18 | A · derivative | 39,715 | $5.67 | $225,184 | 39,715 | No | Form 4 |
| Parsey Merdad | Jun 16 | Jun 18 | A | 26,455 | $0.00 | $0 | 83,746 | No | Form 4 |
| Parsey Merdad | Jun 16 | Jun 18 | A · derivative | 39,715 | $5.67 | $225,184 | 39,715 | No | Form 4 |
| Cadoret-Manier Onaiza | Jun 16 | Jun 18 | A | 26,455 | $0.00 | $0 | 178,156 | No | Form 4 |
| Cadoret-Manier Onaiza | Jun 16 | Jun 18 | A · derivative | 39,715 | $5.67 | $225,184 | 39,715 | No | Form 4 |
| Bhanji Muna | Jun 16 | Jun 18 | A | 26,455 | $0.00 | $0 | 163,808 | No | Form 4 |
| Bhanji Muna | Jun 16 | Jun 18 | A · derivative | 39,715 | $5.67 | $225,184 | 39,715 | No | Form 4 |
| Raab MichaelPresident & CEO | Jun 15 | Jun 17 | M | 20,833 | $0.99 | $20,625 | 1,740,866 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Jun 15 | Jun 17 | S | 41,666 | $5.67 | Sale −$236,246 | 1,699,200 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Jun 15 | Jun 17 | M · derivative | 20,833 | $0.99 | $20,625 | 311,668 | Yes | Form 4 |
| Bishop John ESee Remarks | May 21 | May 22 | S | 2,306 | $6.27 | Sale −$14,459 | 336,845 | No | Form 4 |
| Raab MichaelPresident & CEO | May 21 | May 22 | S | 14,933 | $6.27 | Sale −$93,630 | 1,759,848 | No | Form 4 |
| Raab MichaelPresident & CEO | May 21 | May 22 | S | 7,861 | $6.27 | Sale −$49,288 | 1,751,987 | No | Form 4 |
| Raab MichaelPresident & CEO | May 21 | May 22 | S | 17,926 | $6.27 | Sale −$112,396 | 1,734,061 | No | Form 4 |
| Raab MichaelPresident & CEO | May 21 | May 22 | S | 14,028 | $6.27 | Sale −$87,956 | 1,720,033 | No | Form 4 |
| Williams Laura AChief Patient Officer | May 21 | May 22 | S | 1,503 | $6.27 | Sale −$9,424 | 434,579 | No | Form 4 |
| Williams Laura AChief Patient Officer | May 21 | May 22 | S | 2,157 | $6.27 | Sale −$13,524 | 432,422 | No | Form 4 |
| Williams Laura AChief Patient Officer | May 21 | May 22 | S | 1,911 | $6.27 | Sale −$11,982 | 430,511 | No | Form 4 |
| Williams Laura AChief Patient Officer | May 21 | May 22 | S | 1,418 | $6.27 | Sale −$8,891 | 429,093 | No | Form 4 |
| Kelliher MikeChief Business Officer | May 21 | May 22 | S | 2,900 | $6.27 | Sale −$18,183 | 361,766 | No | Form 4 |
| Kelliher MikeChief Business Officer | May 21 | May 22 | S | 1,870 | $6.27 | Sale −$11,725 | 359,896 | No | Form 4 |
| Kelliher MikeChief Business Officer | May 21 | May 22 | S | 2,478 | $6.27 | Sale −$15,537 | 357,418 | No | Form 4 |
| Foster Eric DuaneChief Commercial Officer | May 21 | May 22 | S | 3,166 | $6.27 | Sale −$19,851 | 422,804 | No | Form 4 |
| Foster Eric DuaneChief Commercial Officer | May 21 | May 22 | S | 2,427 | $6.27 | Sale −$15,217 | 420,377 | No | Form 4 |
| Foster Eric DuaneChief Commercial Officer | May 21 | May 22 | S | 2,405 | $6.27 | Sale −$15,079 | 417,972 | No | Form 4 |
| Reilly Joseph JamesSee Remarks | May 21 | May 22 | S | 2,683 | $6.27 | Sale −$16,822 | 149,107 | No | Form 4 |
| Reilly Joseph JamesSee Remarks | May 21 | May 22 | S | 1,036 | $6.27 | Sale −$6,496 | 149,836 | No | Form 4 |
| Brady James ParkerChief Human Resources Officer | May 21 | May 22 | S | 1,846 | $6.27 | Sale −$11,574 | 261,066 | No | Form 4 |
| Hohenleitner SusanChief Financial Officer | May 21 | May 22 | S | 1,455 | $6.27 | Sale −$9,123 | 229,078 | No | Form 4 |
| Raab MichaelPresident & CEO | May 15 | May 19 | M | 20,833 | $0.99 | $20,625 | 1,816,447 | Yes | Form 4 |
| Raab MichaelPresident & CEO | May 15 | May 19 | S | 41,666 | $6.28 | Sale −$261,662 | 1,774,781 | Yes | Form 4 |
| Raab MichaelPresident & CEO | May 15 | May 19 | M · derivative | 20,833 | $0.99 | $20,625 | 332,501 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Apr 15 | Apr 17 | M | 20,834 | $0.99 | $20,626 | 1,837,282 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Apr 15 | Apr 17 | S | 41,668 | $6.29 | Sale −$262,092 | 1,795,614 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Apr 15 | Apr 17 | M · derivative | 20,834 | $0.99 | $20,626 | 353,334 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Mar 16 | Mar 18 | M | 20,833 | $0.99 | $20,625 | 1,856,986 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Mar 16 | Mar 18 | S | 41,666 | $5.84 | Sale −$243,329 | 1,816,448 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Mar 16 | Mar 18 | M · derivative | 20,833 | $0.99 | $20,625 | 374,168 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Feb 24 | Feb 25 | M | 20,833 | $0.99 | $20,625 | 1,877,819 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Feb 24 | Feb 25 | S | 41,666 | $6.26 | Sale −$260,829 | 1,836,153 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Feb 24 | Feb 25 | M · derivative | 20,833 | $0.99 | $20,625 | 395,001 | Yes | Form 4 |
| Foster Eric DuaneChief Commercial Officer | Feb 20 | Feb 23 | S | 9,176 | $5.87 | Sale −$53,863 | 427,233 | No | Form 4 |
| Foster Eric DuaneChief Commercial Officer | Feb 20 | Feb 23 | S | 1,261 | $5.71 | Sale −$7,200 | 425,972 | No | Form 4 |
| Foster Eric DuaneChief Commercial Officer | Feb 20 | Feb 23 | S | 1 | $5.71 | Sale −$6 | 425,971 | No | Form 4 |
| Foster Eric DuaneChief Commercial Officer | Feb 20 | Feb 23 | S | 1 | $5.70 | Sale −$6 | 425,970 | No | Form 4 |
| Raab MichaelPresident & CEO | Feb 20 | Feb 23 | S | 40,401 | $5.87 | Sale −$237,154 | 1,862,567 | No | Form 4 |
| Raab MichaelPresident & CEO | Feb 20 | Feb 23 | S | 5,576 | $5.71 | Sale −$31,839 | 1,856,991 | No | Form 4 |
| Raab MichaelPresident & CEO | Feb 20 | Feb 23 | S | 2 | $5.70 | Sale −$11 | 1,856,989 | No | Form 4 |
| Raab MichaelPresident & CEO | Feb 20 | Feb 23 | S | 1 | $5.70 | Sale −$6 | 1,856,988 | No | Form 4 |
| Raab MichaelPresident & CEO | Feb 20 | Feb 23 | S | 2 | $5.70 | Sale −$11 | 1,856,986 | No | Form 4 |
| Kelliher MikeSee Remarks | Feb 20 | Feb 23 | S | 8,434 | $5.87 | Sale −$49,508 | 365,827 | No | Form 4 |
| Kelliher MikeSee Remarks | Feb 20 | Feb 23 | S | 1,159 | $5.71 | Sale −$6,618 | 364,668 | No | Form 4 |
| Kelliher MikeSee Remarks | Feb 20 | Feb 23 | S | 2 | $5.71 | Sale −$11 | 364,666 | No | Form 4 |
| Brady James ParkerChief Human Resources Officer | Feb 20 | Feb 23 | S | 2,234 | $5.87 | Sale −$13,114 | 263,221 | No | Form 4 |
| Brady James ParkerChief Human Resources Officer | Feb 20 | Feb 23 | S | 309 | $5.71 | Sale −$1,764 | 262,912 | No | Form 4 |
| Hohenleitner SusanChief Financial Officer | Feb 20 | Feb 23 | S | 1,786 | $5.87 | Sale −$10,484 | 230,780 | No | Form 4 |
| Hohenleitner SusanChief Financial Officer | Feb 20 | Feb 23 | S | 247 | $5.71 | Sale −$1,410 | 230,533 | No | Form 4 |
| Williams Laura ASee Remarks | Feb 20 | Feb 23 | S | 7,192 | $5.87 | Sale −$42,217 | 437,066 | No | Form 4 |
| Williams Laura ASee Remarks | Feb 20 | Feb 23 | S | 984 | $5.71 | Sale −$5,619 | 436,082 | No | Form 4 |
| Reilly Joseph JamesSee Remarks | Feb 20 | Feb 23 | S | 4,387 | $5.87 | Sale −$25,752 | 152,394 | No | Form 4 |
| Reilly Joseph JamesSee Remarks | Feb 20 | Feb 23 | S | 602 | $5.71 | Sale −$3,437 | 151,792 | No | Form 4 |
| Reilly Joseph JamesSee Remarks | Feb 20 | Feb 23 | S | 2 | $5.70 | Sale −$11 | 151,790 | No | Form 4 |
| Bishop John ESee Remarks | Feb 20 | Feb 23 | S | 2,792 | $5.87 | Sale −$16,389 | 339,538 | No | Form 4 |
| Bishop John ESee Remarks | Feb 20 | Feb 23 | S | 386 | $5.71 | Sale −$2,204 | 339,152 | No | Form 4 |
| Bishop John ESee Remarks | Feb 20 | Feb 23 | S | 1 | $5.70 | Sale −$6 | 339,151 | No | Form 4 |
| Mott David M | Feb 20 | Feb 23 | P | 333,333 | $5.84 | Purchase +$1,946,665 | 3,302,918 | No | Form 4 |
| Reilly Joseph JamesSee Remarks | Jan 23 | Jan 27 | A | 46,200 | $0.00 | $0 | 156,781 | No | Form 4 |
| Reilly Joseph JamesSee Remarks | Jan 23 | Jan 27 | A · derivative | 69,360 | $7.77 | $538,927 | 69,360 | No | Form 4 |
| Bishop John ESee Remarks | Jan 23 | Jan 26 | A | 124,330 | $0.00 | $0 | 342,330 | No | Form 4 |
| Bishop John ESee Remarks | Jan 23 | Jan 26 | A · derivative | 186,500 | $7.77 | $1,449,105 | 186,500 | No | Form 4 |
| Williams Laura AChief Patient Officer | Jan 23 | Jan 26 | A | 82,695 | $0.00 | $0 | 444,258 | No | Form 4 |
| Williams Laura AChief Patient Officer | Jan 23 | Jan 26 | A · derivative | 124,040 | $7.77 | $963,791 | 124,040 | No | Form 4 |
| Brady James ParkerChief Human Resources Officer | Jan 23 | Jan 26 | A | 99,455 | $0.00 | $0 | 265,455 | No | Form 4 |
| Brady James ParkerChief Human Resources Officer | Jan 23 | Jan 26 | A · derivative | 149,185 | $7.77 | $1,159,167 | 149,185 | No | Form 4 |
| Raab MichaelPresident & CEO | Jan 23 | Jan 26 | A | 446,220 | $0.00 | $0 | 1,902,968 | No | Form 4 |
| Raab MichaelPresident & CEO | Jan 23 | Jan 26 | A · derivative | 669,330 | $7.77 | $5,200,694 | 669,330 | No | Form 4 |
| Foster Eric DuaneChief Commercial Officer | Jan 23 | Jan 26 | A | 137,945 | $0.00 | $0 | 436,409 | No | Form 4 |
| Foster Eric DuaneChief Commercial Officer | Jan 23 | Jan 26 | A · derivative | 206,915 | $7.77 | $1,607,730 | 206,915 | No | Form 4 |
| Hohenleitner SusanChief Financial Officer | Jan 23 | Jan 26 | A | 85,670 | $0.00 | $0 | 232,566 | No | Form 4 |
| Hohenleitner SusanChief Financial Officer | Jan 23 | Jan 26 | A · derivative | 128,505 | $7.77 | $998,484 | 128,505 | No | Form 4 |
| Kelliher MikeSee Remarks | Jan 23 | Jan 26 | A | 103,080 | $0.00 | $0 | 374,261 | No | Form 4 |
| Kelliher MikeSee Remarks | Jan 23 | Jan 26 | A · derivative | 154,625 | $7.77 | $1,201,436 | 154,625 | No | Form 4 |
| Williams Laura AChief Patient Officer | Jan 8 | Jan 9 | M | 50,000 | $0.99 | $49,500 | 409,896 | Yes | Form 4 |
| Williams Laura AChief Patient Officer | Jan 8 | Jan 9 | S | 50,000 | $6.98 | Sale −$349,000 | 361,563 | Yes | Form 4 |
| Williams Laura AChief Patient Officer | Jan 8 | Jan 9 | M · derivative | 0 | $0.99 | $0 | 62,000 | Yes | Form 4 |
| Reilly Joseph JamesSee Remarks | Nov 21, 2025 | Nov 25, 2025 | S | 11,086 | $5.54 | Sale −$61,416 | 108,914 | No | Form 4 |
| Foster Eric DuaneChief Commercial Officer | Nov 21, 2025 | Nov 25, 2025 | S | 5,814 | $5.54 | Sale −$32,210 | 295,684 | No | Form 4 |
| Williams Laura AChief Patient Officer | Nov 21, 2025 | Nov 25, 2025 | S | 6,426 | $5.54 | Sale −$35,600 | 359,896 | No | Form 4 |
| Kelliher MikeSee Remarks | Nov 21, 2025 | Nov 25, 2025 | S | 5,560 | $5.54 | Sale −$30,802 | 271,181 | No | Form 4 |
| Raab MichaelPresident & CEO | Nov 21, 2025 | Nov 25, 2025 | S | 46,887 | $5.54 | Sale −$259,754 | 1,455,363 | No | Form 4 |
| Grammer Elizabeth ASee Remarks | Nov 21, 2025 | Nov 25, 2025 | S | 5,995 | $5.54 | Sale −$33,212 | 299,895 | No | Form 4 |
| Williams Laura AChief Patient Officer | Aug 26, 2025 | Aug 28, 2025 | M | 50,000 | $0.99 | $49,500 | 446,322 | Yes | Form 4 |
| Williams Laura AChief Patient Officer | Aug 26, 2025 | Aug 28, 2025 | S | 50,000 | $6.12 | Sale −$306,000 | 396,322 | Yes | Form 4 |
| Williams Laura AChief Patient Officer | Aug 26, 2025 | Aug 28, 2025 | S | 30,000 | $6.12 | Sale −$183,600 | 366,322 | Yes | Form 4 |
| Williams Laura AChief Patient Officer | Aug 26, 2025 | Aug 28, 2025 | M · derivative | 50,000 | $0.99 | $49,500 | 112,000 | Yes | Form 4 |
| Kelliher MikeChief Business Officer | Aug 21, 2025 | Aug 28, 2025 | S | 5,417 | $5.93 | Sale −$32,123 | 276,741 | No | Form 4 |
| Foster Eric DuaneChief Commercial Officer | Aug 21, 2025 | Aug 25, 2025 | S | 15,308 | $5.93 | Sale −$90,776 | 301,498 | No | Form 4 |
| Grammer Elizabeth ASee Remarks | Aug 21, 2025 | Aug 25, 2025 | S | 5,841 | $5.93 | Sale −$34,637 | 305,890 | No | Form 4 |
| Raab MichaelPresident & CEO | Aug 21, 2025 | Aug 25, 2025 | S | 45,687 | $5.93 | Sale −$270,924 | 1,502,250 | No | Form 4 |
| Renz Justin AChief Financial Officer | Aug 21, 2025 | Aug 25, 2025 | S | 7,037 | $5.93 | Sale −$41,729 | 409,052 | No | Form 4 |
| Williams Laura AChief Patient Officer | Aug 21, 2025 | Aug 25, 2025 | S | 6,261 | $5.93 | Sale −$37,128 | 396,322 | No | Form 4 |
| Bertrand William C JR | Jun 18, 2025 | Jun 23, 2025 | A | 19,390 | $0.00 | $0 | 249,156 | No | Form 4 |
| Bertrand William C JR | Jun 18, 2025 | Jun 23, 2025 | A | 41,551 | $0.00 | $0 | 290,707 | No | Form 4 |
| Bertrand William C JR | Jun 18, 2025 | Jun 23, 2025 | A · derivative | 54,059 | $3.61 | $195,153 | 54,059 | No | Form 4 |
| Bhanji Muna | Jun 18, 2025 | Jun 23, 2025 | A | 41,551 | $0.00 | $0 | 137,353 | No | Form 4 |
| Bhanji Muna | Jun 18, 2025 | Jun 23, 2025 | A · derivative | 54,059 | $3.61 | $195,153 | 54,059 | No | Form 4 |
| Cadoret-Manier Onaiza | Jun 18, 2025 | Jun 23, 2025 | A | 41,551 | $0.00 | $0 | 151,701 | No | Form 4 |
| Cadoret-Manier Onaiza | Jun 18, 2025 | Jun 23, 2025 | A · derivative | 54,059 | $3.61 | $195,153 | 54,059 | No | Form 4 |
| Mott David M | Jun 18, 2025 | Jun 23, 2025 | A | 31,163 | $0.00 | $0 | 2,928,034 | No | Form 4 |
| Mott David M | Jun 18, 2025 | Jun 23, 2025 | A | 41,551 | $0.00 | $0 | 2,969,585 | No | Form 4 |
| Mott David M | Jun 18, 2025 | Jun 23, 2025 | A · derivative | 54,059 | $3.61 | $195,153 | 54,059 | No | Form 4 |
| Parsey Merdad | Jun 18, 2025 | Jun 23, 2025 | A | 15,235 | $0.00 | $0 | 57,291 | No | Form 4 |
| Rodgers Richard J | Jun 18, 2025 | Jun 23, 2025 | A | 21,468 | $0.00 | $0 | 371,992 | No | Form 4 |
| Rodgers Richard J | Jun 18, 2025 | Jun 23, 2025 | A | 41,551 | $0.00 | $0 | 413,543 | No | Form 4 |
| Rodgers Richard J | Jun 18, 2025 | Jun 23, 2025 | A · derivative | 54,059 | $3.61 | $195,153 | 54,059 | No | Form 4 |
| Bazemore Robert B | Jun 18, 2025 | Jun 23, 2025 | A | 41,551 | $0.00 | $0 | 41,551 | No | Form 4 |
| Bazemore Robert B | Jun 18, 2025 | Jun 23, 2025 | A · derivative | 54,059 | $3.61 | $195,153 | 54,059 | No | Form 4 |
| Mott David M | Jun 16, 2025 | Jun 18, 2025 | P | 200,000 | $3.63 | Purchase +$726,000 | 2,896,871 | No | Form 4 |
| Mott David M | Jun 9, 2025 | Jun 11, 2025 | P | 200,000 | $3.69 | Purchase +$738,000 | 2,696,871 | No | Form 4 |
| Foster Eric DuaneChief Commercial Officer | May 20, 2025 | May 22, 2025 | S | 2,507 | $4.08 | Sale −$10,229 | 316,806 | No | Form 4 |
| Grammer Elizabeth ASee Remarks | May 20, 2025 | May 22, 2025 | S | 5,992 | $4.08 | Sale −$24,447 | 311,731 | No | Form 4 |
| Kelliher MikeSee Remarks | May 20, 2025 | May 22, 2025 | S | 14,522 | $4.08 | Sale −$59,250 | 282,158 | No | Form 4 |
| Raab MichaelPresident & CEO | May 20, 2025 | May 22, 2025 | S | 46,817 | $4.08 | Sale −$191,013 | 1,547,937 | No | Form 4 |
| Renz Justin AChief Financial Officer | May 20, 2025 | May 22, 2025 | S | 7,218 | $4.08 | Sale −$29,449 | 416,089 | No | Form 4 |
| Williams Laura AChief Medical Officer | May 20, 2025 | May 22, 2025 | S | 6,421 | $4.08 | Sale −$26,198 | 402,583 | No | Form 4 |
| Mott David M | May 15, 2025 | May 19, 2025 | P | 100,000 | $3.29 | Purchase +$329,000 | 2,496,871 | No | Form 4 |
| Parsey Merdad | Apr 28, 2025 | May 14, 2025 | A | 42,056 | $0.00 | $0 | 42,056 | No | Form 4 |
| Parsey Merdad | Apr 28, 2025 | May 14, 2025 | A · derivative | 64,457 | $5.35 | $344,845 | 64,457 | No | Form 4 |
| Raab MichaelPresident & CEO | May 2, 2025 | May 5, 2025 | M | 20,833 | $0.99 | $20,625 | 1,636,420 | Yes | Form 4 |
| Raab MichaelPresident & CEO | May 2, 2025 | May 5, 2025 | S | 41,666 | $4.25 | Sale −$177,081 | 1,594,754 | Yes | Form 4 |
| Raab MichaelPresident & CEO | May 2, 2025 | May 5, 2025 | M · derivative | 20,833 | $0.99 | $20,625 | 415,834 | Yes | Form 4 |
| Mott David M | May 2, 2025 | May 5, 2025 | P | 381,377 | $4.22 | Purchase +$1,609,411 | 2,396,871 | No | Form 4 |
| Raab MichaelPresident & CEO | Apr 4, 2025 | Apr 8, 2025 | M | 20,833 | $0.99 | $20,625 | 1,657,253 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Apr 4, 2025 | Apr 8, 2025 | S | 41,666 | $4.59 | Sale −$191,247 | 1,615,587 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Apr 4, 2025 | Apr 8, 2025 | M · derivative | 20,833 | $0.99 | $20,625 | 436,667 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Mar 7, 2025 | Mar 7, 2025 | M | 20,834 | $0.99 | $20,626 | 1,676,806 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Mar 7, 2025 | Mar 7, 2025 | S | 41,668 | $5.36 | Sale −$223,340 | 1,635,138 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Mar 7, 2025 | Mar 7, 2025 | M · derivative | 20,834 | $0.99 | $20,626 | 457,500 | Yes | Form 4 |
| Foster Eric DuaneChief Commercial Officer | Feb 25, 2025 | Feb 27, 2025 | A | 136,680 | $0.00 | $0 | 316,680 | No | Form 4 |
| Foster Eric DuaneChief Commercial Officer | Feb 25, 2025 | Feb 27, 2025 | A · derivative | 205,019 | $5.18 | $1,061,998 | 205,019 | No | Form 4 |
| Grammer Elizabeth ASee Remarks | Feb 25, 2025 | Feb 27, 2025 | A | 136,680 | $0.00 | $0 | 317,723 | No | Form 4 |
| Grammer Elizabeth ASee Remarks | Feb 25, 2025 | Feb 27, 2025 | A · derivative | 205,019 | $5.18 | $1,061,998 | 205,019 | No | Form 4 |
| Kelliher MikeSee Remarks | Feb 25, 2025 | Feb 27, 2025 | A | 136,680 | $0.00 | $0 | 296,680 | No | Form 4 |
| Kelliher MikeSee Remarks | Feb 25, 2025 | Feb 27, 2025 | A · derivative | 205,019 | $5.18 | $1,061,998 | 205,019 | No | Form 4 |
| Raab MichaelPresident & CEO | Feb 25, 2025 | Feb 27, 2025 | A | 570,217 | $0.00 | $0 | 1,655,972 | No | Form 4 |
| Raab MichaelPresident & CEO | Feb 25, 2025 | Feb 27, 2025 | A · derivative | 855,326 | $5.18 | $4,430,589 | 855,326 | No | Form 4 |
| Renz Justin AChief Financial Officer | Feb 25, 2025 | Feb 27, 2025 | A | 136,680 | $0.00 | $0 | 422,648 | No | Form 4 |
| Renz Justin AChief Financial Officer | Feb 25, 2025 | Feb 27, 2025 | A · derivative | 205,019 | $5.18 | $1,061,998 | 205,019 | No | Form 4 |
| Williams Laura AChief Medical Officer | Feb 25, 2025 | Feb 27, 2025 | A | 105,200 | $0.00 | $0 | 409,004 | No | Form 4 |
| Williams Laura AChief Medical Officer | Feb 25, 2025 | Feb 27, 2025 | A · derivative | 157,700 | $5.18 | $816,886 | 157,700 | No | Form 4 |
| Mott David M | Feb 24, 2025 | Feb 26, 2025 | P | 77,729 | $5.00 | Purchase +$388,645 | 2,015,494 | No | Form 4 |
| Grammer Elizabeth ASee Remarks | Feb 20, 2025 | Feb 21, 2025 | S | 4,291 | $5.62 | Sale −$24,115 | 181,043 | No | Form 4 |
| Raab MichaelPresident & CEO | Feb 20, 2025 | Feb 21, 2025 | S | 22,964 | $5.62 | Sale −$129,058 | 1,085,755 | No | Form 4 |
| Renz Justin AChief Financial Officer | Feb 20, 2025 | Feb 21, 2025 | S | 5,171 | $5.62 | Sale −$29,061 | 285,968 | No | Form 4 |
| Williams Laura AChief Medical Officer | Feb 20, 2025 | Feb 21, 2025 | S | 4,941 | $5.62 | Sale −$27,768 | 303,804 | No | Form 4 |
| Raab MichaelPresident & CEO | Jan 31, 2025 | Jan 31, 2025 | M | 20,833 | $0.99 | $20,625 | 1,150,385 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Jan 31, 2025 | Jan 31, 2025 | S | 41,666 | $5.36 | Sale −$223,330 | 1,108,719 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Jan 31, 2025 | Jan 31, 2025 | M · derivative | 20,833 | $0.99 | $20,625 | 478,334 | Yes | Form 4 |
| Mott David M | Jan 21, 2025 | Jan 22, 2025 | P | 199,000 | $4.99 | Purchase +$993,010 | 1,937,765 | No | Form 4 |
| Rodgers Richard J | Jan 16, 2025 | Jan 17, 2025 | M | 100,000 | $0.55 | $55,000 | 350,524 | No | Form 4 |
| Rodgers Richard J | Jan 16, 2025 | Jan 17, 2025 | M · derivative | 100,000 | $0.55 | $55,000 | not reported | No | Form 4 |
| Raab MichaelPresident & CEO | Jan 7, 2025 | Jan 10, 2025 | M | 20,833 | $0.99 | $20,625 | 1,171,218 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Jan 7, 2025 | Jan 10, 2025 | S | 41,666 | $5.31 | Sale −$221,246 | 1,129,552 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Jan 7, 2025 | Jan 10, 2025 | M · derivative | 20,833 | $0.99 | $20,625 | 499,167 | Yes | Form 4 |
| Mott David M | Dec 26, 2024 | Dec 27, 2024 | M | 100,000 | $0.55 | $55,000 | 1,738,765 | No | Form 4 |
| Mott David M | Dec 26, 2024 | Dec 27, 2024 | M · derivative | 100,000 | $0.55 | $55,000 | not reported | No | Form 4 |
| Mott David M | Dec 19, 2024 | Dec 23, 2024 | P | 213,300 | $4.67 | Purchase +$996,111 | 1,638,765 | No | Form 4 |
| Raab MichaelPresident & CEO | Dec 10, 2024 | Dec 12, 2024 | M | 25,000 | $0.99 | $24,750 | 1,175,385 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Dec 10, 2024 | Dec 12, 2024 | S | 25,000 | $5.26 | Sale −$131,500 | 1,150,385 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Dec 10, 2024 | Dec 12, 2024 | M · derivative | 25,000 | $0.99 | $24,750 | 520,000 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Nov 25, 2024 | Nov 27, 2024 | S | 25,000 | $5.38 | Sale −$134,500 | 1,150,385 | Yes | Form 4 |
| Blanks RobertSee Remarks | Nov 20, 2024 | Nov 22, 2024 | S | 4,941 | $4.79 | Sale −$23,667 | 314,421 | No | Form 4 |
| Grammer Elizabeth ASee Remarks | Nov 20, 2024 | Nov 22, 2024 | S | 7,046 | $4.79 | Sale −$33,750 | 185,334 | No | Form 4 |
| Raab MichaelPresident & CEO | Nov 20, 2024 | Nov 22, 2024 | S | 31,980 | $4.79 | Sale −$153,184 | 1,175,385 | No | Form 4 |
| Renz Justin AChief Financial Officer | Nov 20, 2024 | Nov 22, 2024 | S | 5,260 | $4.79 | Sale −$25,195 | 291,139 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Nov 20, 2024 | Nov 22, 2024 | S | 4,941 | $4.79 | Sale −$23,667 | 297,005 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Nov 20, 2024 | Nov 22, 2024 | S | 2,243 | $4.79 | Sale −$10,744 | 151,373 | No | Form 4 |
| Williams Laura AChief Medical Officer | Nov 20, 2024 | Nov 22, 2024 | S | 7,366 | $4.79 | Sale −$35,283 | 308,745 | No | Form 4 |
| Mott David M | Nov 13, 2024 | Nov 14, 2024 | P | 215,868 | $4.62 | Purchase +$997,310 | 1,425,465 | No | Form 4 |
| Raab MichaelPresident & CEO | Nov 11, 2024 | Nov 12, 2024 | S | 2,743 | $4.90 | Sale −$13,441 | 1,207,365 | Yes | Form 4 |
| Rosenbaum David P.Chief Development Officer | Nov 6, 2024 | Nov 8, 2024 | M | 27,171 | $2.32 | $63,037 | 180,787 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Nov 6, 2024 | Nov 8, 2024 | S | 27,171 | $6.10 | Sale −$165,743 | 153,616 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Nov 6, 2024 | Nov 8, 2024 | M · derivative | 27,171 | $2.32 | $63,037 | not reported | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Nov 4, 2024 | Nov 6, 2024 | M | 27,172 | $2.32 | $63,039 | 180,788 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Nov 4, 2024 | Nov 6, 2024 | S | 27,172 | $5.95 | Sale −$161,673 | 153,616 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Nov 4, 2024 | Nov 6, 2024 | M · derivative | 27,172 | $2.32 | $63,039 | 27,171 | No | Form 4 |
| Raab MichaelPresident & CEO | Oct 28, 2024 | Oct 31, 2024 | M | 25,000 | $0.99 | $24,750 | 1,235,108 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Oct 28, 2024 | Oct 31, 2024 | S | 25,000 | $5.91 | Sale −$147,750 | 1,210,108 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Oct 28, 2024 | Oct 31, 2024 | M · derivative | 25,000 | $0.99 | $24,750 | 545,000 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Oct 11, 2024 | Oct 15, 2024 | S | 7,500 | $6.01 | Sale −$45,075 | 1,210,108 | Yes | Form 4 |
| Rosenbaum David P.Chief Development Officer | Sep 27, 2024 | Oct 1, 2024 | S | 49,564 | $6.92 | Sale −$342,983 | 301,946 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Sep 26, 2024 | Sep 27, 2024 | S | 3,000 | $6.07 | Sale −$18,210 | 1,217,608 | Yes | Form 4 |
| Rosenbaum David P.Chief Development Officer | Sep 13, 2024 | Sep 16, 2024 | S | 5,312 | $6.26 | Sale −$33,253 | 153,616 | No | Form 4 |
| Raab MichaelPresident & CEO | Sep 11, 2024 | Sep 13, 2024 | M | 35,000 | $0.99 | $34,650 | 1,255,608 | No | Form 4 |
| Raab MichaelPresident & CEO | Sep 11, 2024 | Sep 13, 2024 | S | 35,000 | $5.61 | Sale −$196,350 | 1,220,608 | No | Form 4 |
| Raab MichaelPresident & CEO | Sep 11, 2024 | Sep 13, 2024 | M · derivative | 35,000 | $0.99 | $34,650 | 570,000 | No | Form 4 |
| Raab MichaelPresident & CEO | Aug 27, 2024 | Aug 28, 2024 | S | 7,500 | $6.22 | Sale −$46,650 | 1,219,509 | Yes | Form 4 |
| Blanks RobertSee Remarks | Aug 20, 2024 | Aug 22, 2024 | S | 4,969 | $5.86 | Sale −$29,118 | 319,362 | No | Form 4 |
| Felsch Robert OraSee Remarks | Aug 20, 2024 | Aug 22, 2024 | S | 3,567 | $5.86 | Sale −$20,903 | 91,560 | No | Form 4 |
| Grammer Elizabeth ASee Remarks | Aug 20, 2024 | Aug 22, 2024 | S | 7,089 | $5.86 | Sale −$41,542 | 192,380 | No | Form 4 |
| Raab MichaelPresident & CEO | Aug 20, 2024 | Aug 22, 2024 | S | 32,225 | $5.86 | Sale −$188,839 | 1,227,009 | No | Form 4 |
| Renz Justin AChief Financial Officer | Aug 20, 2024 | Aug 22, 2024 | S | 5,289 | $5.86 | Sale −$30,994 | 295,257 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Aug 20, 2024 | Aug 22, 2024 | S | 4,969 | $5.86 | Sale −$29,118 | 351,510 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Aug 20, 2024 | Aug 22, 2024 | S | 2,250 | $5.86 | Sale −$13,185 | 156,252 | No | Form 4 |
| Williams Laura AChief Medical Officer | Aug 20, 2024 | Aug 22, 2024 | S | 7,412 | $5.86 | Sale −$43,434 | 314,740 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Aug 20, 2024 | Aug 20, 2024 | M | 20,507 | $0.99 | $20,302 | 179,009 | Yes | Form 4 |
| Rosenbaum David P.Chief Development Officer | Aug 20, 2024 | Aug 20, 2024 | S | 20,507 | $6.00 | Sale −$123,042 | 158,502 | Yes | Form 4 |
| Rosenbaum David P.Chief Development Officer | Aug 20, 2024 | Aug 20, 2024 | M · derivative | 20,507 | $0.99 | $20,302 | 49,806 | Yes | Form 4 |
| Rosenbaum David P.Chief Development Officer | Aug 16, 2024 | Aug 20, 2024 | S | 20,000 | $5.94 | Sale −$118,800 | 356,479 | Yes | Form 4 |
| Foster Eric DuaneChief Commercial Officer | Aug 8, 2024 | Aug 16, 2024 | A | 180,000 | $0.00 | $0 | 180,000 | No | Form 4 |
| Foster Eric DuaneChief Commercial Officer | Aug 8, 2024 | Aug 16, 2024 | A · derivative | 230,000 | $5.87 | $1,350,100 | 230,000 | No | Form 4 |
| Raab MichaelPresident & CEO | Aug 12, 2024 | Aug 14, 2024 | S | 1,229 | $5.71 | Sale −$7,018 | 1,259,234 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Jul 29, 2024 | Jul 31, 2024 | M | 30,000 | $0.99 | $29,700 | 1,290,463 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Jul 29, 2024 | Jul 31, 2024 | S | 30,000 | $5.64 | Sale −$169,200 | 1,260,463 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Jul 29, 2024 | Jul 31, 2024 | M · derivative | 30,000 | $0.99 | $29,700 | 605,000 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Jul 15, 2024 | Jul 17, 2024 | S | 7,500 | $5.97 | Sale −$44,775 | 1,260,463 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Jun 28, 2024 | Jun 28, 2024 | S | 2,310 | $6.59 | Sale −$15,223 | 1,267,963 | Yes | Form 4 |
| Blanks RobertSee Remarks | Jun 21, 2024 | Jun 25, 2024 | S | 38,000 | $5.96 | Sale −$226,480 | 324,331 | Yes | Form 4 |
| Mott David M | Jun 14, 2024 | Jun 17, 2024 | A | 17,322 | $0.00 | $0 | 1,209,597 | No | Form 4 |
| Mott David M | Jun 14, 2024 | Jun 17, 2024 | A · derivative | 40,243 | $6.35 | $255,543 | 40,243 | No | Form 4 |
| Bazemore Robert B | Jun 14, 2024 | Jun 17, 2024 | A · derivative | 40,243 | $6.35 | $255,543 | 40,243 | No | Form 4 |
| Cadoret-Manier Onaiza | Jun 14, 2024 | Jun 17, 2024 | A · derivative | 40,243 | $6.35 | $255,543 | 40,243 | No | Form 4 |
| Bertrand William C JR | Jun 14, 2024 | Jun 17, 2024 | A | 11,023 | $0.00 | $0 | 229,766 | No | Form 4 |
| Bertrand William C JR | Jun 14, 2024 | Jun 17, 2024 | A · derivative | 40,243 | $6.35 | $255,543 | 40,243 | No | Form 4 |
| Bhanji Muna | Jun 14, 2024 | Jun 17, 2024 | A · derivative | 40,243 | $6.35 | $255,543 | 40,243 | No | Form 4 |
| Rodgers Richard J | Jun 14, 2024 | Jun 17, 2024 | A | 12,204 | $0.00 | $0 | 250,524 | No | Form 4 |
| Rodgers Richard J | Jun 14, 2024 | Jun 17, 2024 | A · derivative | 40,243 | $6.35 | $255,543 | 40,243 | No | Form 4 |
| Raab MichaelPresident & CEO | Jun 13, 2024 | Jun 17, 2024 | M | 35,000 | $0.99 | $34,650 | 1,305,273 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Jun 13, 2024 | Jun 17, 2024 | S | 35,000 | $6.65 | Sale −$232,750 | 1,270,273 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Jun 13, 2024 | Jun 17, 2024 | M · derivative | 35,000 | $0.99 | $34,650 | 665,000 | Yes | Form 4 |
| Williams Laura AChief Medical Officer | Jun 5, 2024 | Jun 7, 2024 | M | 100,000 | $2.75 | $275,000 | 467,152 | No | Form 4 |
| Williams Laura AChief Medical Officer | Jun 5, 2024 | Jun 7, 2024 | S | 45,000 | $7.12 | Sale −$320,400 | 422,152 | No | Form 4 |
| Williams Laura AChief Medical Officer | Jun 5, 2024 | Jun 7, 2024 | S | 100,000 | $7.13 | Sale −$713,000 | 322,152 | No | Form 4 |
| Williams Laura AChief Medical Officer | Jun 5, 2024 | Jun 7, 2024 | M · derivative | 100,000 | $2.75 | $275,000 | 251,000 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Jun 3, 2024 | Jun 5, 2024 | S | 17,872 | $7.00 | Sale −$125,104 | 158,502 | No | Form 4 |
| Raab MichaelPresident & CEO | May 29, 2024 | May 31, 2024 | S | 7,500 | $6.72 | Sale −$50,400 | 1,270,273 | Yes | Form 4 |
| Blanks RobertSee Remarks | May 21, 2024 | May 23, 2024 | S | 4,855 | $7.81 | Sale −$37,918 | 362,331 | No | Form 4 |
| Felsch Robert OraSee Remarks | May 21, 2024 | May 23, 2024 | S | 3,485 | $7.81 | Sale −$27,218 | 95,127 | No | Form 4 |
| Grammer Elizabeth ASee Remarks | May 21, 2024 | May 23, 2024 | S | 6,927 | $7.81 | Sale −$54,100 | 199,469 | No | Form 4 |
| Raab MichaelPresident & CEO | May 21, 2024 | May 23, 2024 | S | 31,484 | $7.81 | Sale −$245,890 | 1,277,773 | No | Form 4 |
| Renz Justin AChief Financial Officer | May 21, 2024 | May 23, 2024 | S | 5,167 | $7.81 | Sale −$40,354 | 300,546 | No | Form 4 |
| Rodriguez SusanChief Commercial Officer | May 21, 2024 | May 23, 2024 | S | 6,703 | $7.81 | Sale −$52,350 | 449,092 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | May 21, 2024 | May 23, 2024 | S | 4,855 | $7.81 | Sale −$37,918 | 376,479 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | May 21, 2024 | May 23, 2024 | S | 2,198 | $7.81 | Sale −$17,166 | 176,374 | No | Form 4 |
| Williams Laura AChief Medical Officer | May 21, 2024 | May 23, 2024 | S | 4,794 | $7.81 | Sale −$37,441 | 367,152 | No | Form 4 |
| Raab MichaelPresident & CEO | May 14, 2024 | May 15, 2024 | S | 3,000 | $7.99 | Sale −$23,970 | 1,307,933 | Yes | Form 4 |
| Grammer Elizabeth ASee Remarks | May 6, 2024 | May 9, 2024 | M | 110,250 | $0.99 | $109,148 | 378,243 | No | Form 4 |
| Grammer Elizabeth ASee Remarks | May 6, 2024 | May 9, 2024 | M | 109,687 | $2.75 | $301,639 | 487,930 | No | Form 4 |
| Grammer Elizabeth ASee Remarks | May 6, 2024 | May 9, 2024 | S | 64,233 | $8.87 | Sale −$569,747 | 423,697 | No | Form 4 |
| Grammer Elizabeth ASee Remarks | May 6, 2024 | May 9, 2024 | S | 219,937 | $8.88 | Sale −$1,953,041 | 203,760 | No | Form 4 |
| Grammer Elizabeth ASee Remarks | May 6, 2024 | May 9, 2024 | M · derivative | 110,250 | $0.99 | $109,148 | 85,750 | No | Form 4 |
| Grammer Elizabeth ASee Remarks | May 6, 2024 | May 9, 2024 | M · derivative | 109,687 | $2.75 | $301,639 | 241,313 | No | Form 4 |
| Felsch Robert OraSee Remarks | May 6, 2024 | May 9, 2024 | M | 79,101 | $0.84 | $66,445 | 263,935 | No | Form 4 |
| Felsch Robert OraSee Remarks | May 6, 2024 | May 9, 2024 | M | 40,000 | $2.75 | $110,000 | 303,935 | No | Form 4 |
| Felsch Robert OraSee Remarks | May 6, 2024 | May 9, 2024 | S | 152,988 | $8.81 | Sale −$1,347,824 | 150,947 | No | Form 4 |
| Felsch Robert OraSee Remarks | May 6, 2024 | May 9, 2024 | S | 55,000 | $8.80 | Sale −$484,000 | 95,947 | No | Form 4 |
| Felsch Robert OraSee Remarks | May 6, 2024 | May 9, 2024 | M · derivative | 79,101 | $0.84 | $66,445 | 61,525 | No | Form 4 |
| Felsch Robert OraSee Remarks | May 6, 2024 | May 9, 2024 | M · derivative | 40,000 | $2.75 | $110,000 | 80,000 | No | Form 4 |
| Williams Laura AChief Medical Officer | May 3, 2024 | May 7, 2024 | M | 30,000 | $0.99 | $29,700 | 410,138 | Yes | Form 4 |
| Williams Laura AChief Medical Officer | May 3, 2024 | May 7, 2024 | S | 39,949 | $8.35 | Sale −$333,574 | 370,189 | Yes | Form 4 |
| Williams Laura AChief Medical Officer | May 3, 2024 | May 7, 2024 | M · derivative | 30,000 | $0.99 | $29,700 | 162,000 | Yes | Form 4 |
| Grammer Elizabeth ASee Remarks | May 3, 2024 | May 7, 2024 | S | 45,000 | $9.00 | Sale −$405,000 | 267,993 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Apr 29, 2024 | May 1, 2024 | M | 30,000 | $0.99 | $29,700 | 1,340,933 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Apr 29, 2024 | May 1, 2024 | S | 30,000 | $6.40 | Sale −$192,000 | 1,310,933 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Apr 29, 2024 | May 1, 2024 | M · derivative | 30,000 | $0.99 | $29,700 | 670,000 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Apr 15, 2024 | Apr 17, 2024 | S | 7,500 | $7.06 | Sale −$52,950 | 1,310,933 | Yes | Form 4 |
| Raab MichaelPresident & CEO | Apr 1, 2024 | Apr 2, 2024 | S | 1,518 | $7.31 | Sale −$11,097 | 1,318,433 | Yes | Form 4 |
| Kelliher MikeSee Remarks | Mar 25, 2024 | Mar 27, 2024 | A | 160,000 | $0.00 | $0 | 160,000 | No | Form 4 |
| Kelliher MikeSee Remarks | Mar 25, 2024 | Mar 27, 2024 | A · derivative | 205,000 | $7.70 | $1,578,500 | 205,000 | No | Form 4 |
| Grammer Elizabeth ASee Remarks | Mar 20, 2024 | Mar 22, 2024 | S | 86,000 | $7.73 | Sale −$664,780 | 312,993 | Yes | Form 4 |
| Blanks RobertSee Remarks | Mar 15, 2024 | Mar 22, 2024 | G | 1,000 | $0.00 | $0 | 367,186 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Feb 26, 2024 | Feb 28, 2024 | S | 5,183 | $9.20 | Sale −$47,684 | 175,936 | No | Form 4 |
| Williams Laura AChief Medical Officer | Feb 20, 2024 | Feb 22, 2024 | S | 4,803 | $8.75 | Sale −$42,026 | 380,138 | No | Form 4 |
| Felsch Robert OraSee Remarks | Feb 20, 2024 | Feb 22, 2024 | S | 2,352 | $8.75 | Sale −$20,580 | 184,834 | No | Form 4 |
| Rodriguez SusanChief Commercial Officer | Feb 20, 2024 | Feb 22, 2024 | S | 6,928 | $8.75 | Sale −$60,620 | 452,795 | No | Form 4 |
| Grammer Elizabeth ASee Remarks | Feb 20, 2024 | Feb 22, 2024 | S | 4,432 | $8.75 | Sale −$38,780 | 398,993 | No | Form 4 |
| Blanks RobertSee Remarks | Feb 20, 2024 | Feb 22, 2024 | S | 5,017 | $8.75 | Sale −$43,899 | 368,186 | No | Form 4 |
| Raab MichaelPresident & CEO | Feb 20, 2024 | Feb 22, 2024 | S | 22,917 | $8.75 | Sale −$200,524 | 1,319,951 | No | Form 4 |
| Renz Justin AChief Financial Officer | Feb 20, 2024 | Feb 22, 2024 | S | 5,341 | $8.75 | Sale −$46,734 | 304,835 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Feb 20, 2024 | Feb 22, 2024 | S | 5,017 | $8.75 | Sale −$43,899 | 378,985 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Feb 20, 2024 | Feb 22, 2024 | S | 2,294 | $8.75 | Sale −$20,073 | 181,119 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Feb 8, 2024 | Feb 9, 2024 | S | 15,344 | $9.18 | Sale −$140,858 | 384,002 | Yes | Form 4 |
| Blanks RobertSee Remarks | Jan 16, 2024 | Jan 18, 2024 | A | 112,750 | $0.00 | $0 | 373,203 | No | Form 4 |
| Blanks RobertSee Remarks | Jan 16, 2024 | Jan 18, 2024 | A · derivative | 145,000 | $8.78 | $1,273,100 | 145,000 | No | Form 4 |
| Felsch Robert OraSee Remarks | Jan 16, 2024 | Jan 18, 2024 | A | 70,120 | $0.00 | $0 | 187,186 | No | Form 4 |
| Felsch Robert OraSee Remarks | Jan 16, 2024 | Jan 18, 2024 | A · derivative | 99,000 | $8.78 | $869,220 | 99,000 | No | Form 4 |
| Grammer Elizabeth ASee Remarks | Jan 16, 2024 | Jan 18, 2024 | A | 127,750 | $0.00 | $0 | 403,425 | No | Form 4 |
| Grammer Elizabeth ASee Remarks | Jan 16, 2024 | Jan 18, 2024 | A · derivative | 164,000 | $8.78 | $1,439,920 | 164,000 | No | Form 4 |
| Raab MichaelPresident & CEO | Jan 16, 2024 | Jan 18, 2024 | A | 475,000 | $0.00 | $0 | 1,342,868 | No | Form 4 |
| Raab MichaelPresident & CEO | Jan 16, 2024 | Jan 18, 2024 | A · derivative | 605,904 | $8.78 | $5,319,837 | 605,904 | No | Form 4 |
| Renz Justin AChief Financial Officer | Jan 16, 2024 | Jan 18, 2024 | A | 127,750 | $0.00 | $0 | 310,176 | No | Form 4 |
| Renz Justin AChief Financial Officer | Jan 16, 2024 | Jan 18, 2024 | A · derivative | 164,000 | $8.78 | $1,439,920 | 164,000 | No | Form 4 |
| Rodriguez SusanChief Commercial Officer | Jan 16, 2024 | Jan 18, 2024 | A | 112,750 | $0.00 | $0 | 459,723 | No | Form 4 |
| Rodriguez SusanChief Commercial Officer | Jan 16, 2024 | Jan 18, 2024 | A · derivative | 145,000 | $8.78 | $1,273,100 | 145,000 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Jan 16, 2024 | Jan 18, 2024 | A | 112,750 | $0.00 | $0 | 399,346 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Jan 16, 2024 | Jan 18, 2024 | A | 70,120 | $0.00 | $0 | 183,413 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Jan 16, 2024 | Jan 18, 2024 | A · derivative | 145,000 | $8.78 | $1,273,100 | 145,000 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Jan 16, 2024 | Jan 18, 2024 | A · derivative | 99,000 | $8.78 | $869,220 | 99,000 | No | Form 4 |
| Williams Laura AChief Medical Officer | Jan 16, 2024 | Jan 18, 2024 | A | 118,750 | $0.00 | $0 | 384,941 | No | Form 4 |
| Williams Laura AChief Medical Officer | Jan 16, 2024 | Jan 18, 2024 | A · derivative | 152,127 | $8.78 | $1,335,675 | 152,127 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Jan 8, 2024 | Jan 10, 2024 | S | 30,000 | $6.64 | Sale −$199,200 | 286,596 | Yes | Form 4 |
| Renz Justin AChief Financial Officer | Dec 26, 2023 | Dec 28, 2023 | M | 75,000 | $0.99 | $74,250 | 407,426 | Yes | Form 4 |
| Renz Justin AChief Financial Officer | Dec 26, 2023 | Dec 28, 2023 | S | 225,000 | $6.36 | Sale −$1,431,000 | 182,426 | Yes | Form 4 |
| Renz Justin AChief Financial Officer | Dec 26, 2023 | Dec 28, 2023 | M · derivative | 75,000 | $0.99 | $74,250 | 121,000 | Yes | Form 4 |
| Rosenbaum David P.Chief Development Officer | Dec 18, 2023 | Dec 20, 2023 | S | 5,675 | $6.07 | Sale −$34,447 | 316,596 | Yes | Form 4 |
| Rosenbaum David P.Chief Development Officer | Dec 14, 2023 | Dec 15, 2023 | S | 7,000 | $5.55 | Sale −$38,850 | 322,271 | Yes | Form 4 |
| Grammer Elizabeth ASee Remarks | Dec 11, 2023 | Dec 13, 2023 | S | 50,000 | $5.08 | Sale −$254,000 | 275,675 | Yes | Form 4 |
| Rosenbaum David P.Chief Development Officer | Dec 8, 2023 | Dec 8, 2023 | S | 20,000 | $5.27 | Sale −$105,400 | 329,271 | Yes | Form 4 |
| Rosenbaum David P.Chief Development Officer | Dec 5, 2023 | Dec 6, 2023 | S | 10,272 | $5.00 | Sale −$51,360 | 349,271 | Yes | Form 4 |
| Rosenbaum David P.Chief Development Officer | Nov 30, 2023 | Dec 1, 2023 | S | 3,000 | $4.50 | Sale −$13,500 | 359,543 | Yes | Form 4 |
| Blanks RobertSee Remarks | Nov 20, 2023 | Nov 22, 2023 | S | 2,835 | $4.36 | Sale −$12,361 | 260,453 | No | Form 4 |
| Felsch Robert OraSee Remarks | Nov 20, 2023 | Nov 22, 2023 | S | 1,044 | $4.36 | Sale −$4,552 | 117,066 | No | Form 4 |
| Grammer Elizabeth ASee Remarks | Nov 20, 2023 | Nov 22, 2023 | S | 2,384 | $4.36 | Sale −$10,394 | 325,675 | No | Form 4 |
| Raab MichaelPresident & CEO | Nov 20, 2023 | Nov 22, 2023 | S | 11,368 | $4.36 | Sale −$49,564 | 867,868 | No | Form 4 |
| Renz Justin AChief Financial Officer | Nov 20, 2023 | Nov 22, 2023 | S | 2,873 | $4.36 | Sale −$12,526 | 332,426 | No | Form 4 |
| Rodriguez SusanChief Commercial Officer | Nov 20, 2023 | Nov 22, 2023 | S | 4,714 | $4.36 | Sale −$20,553 | 346,973 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Nov 20, 2023 | Nov 22, 2023 | S | 2,835 | $4.36 | Sale −$12,361 | 362,543 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Nov 20, 2023 | Nov 22, 2023 | S | 932 | $4.36 | Sale −$4,064 | 113,293 | No | Form 4 |
| Williams Laura AChief Medical Officer | Nov 20, 2023 | Nov 22, 2023 | S | 2,581 | $4.36 | Sale −$11,253 | 266,191 | No | Form 4 |
| Williams Laura AChief Medical Officer | Nov 15, 2023 | Nov 17, 2023 | S | 25,000 | $4.00 | Sale −$100,000 | 266,839 | No | Form 4 |
| Rosenbaum David P.Chief Development Officer | Oct 10, 2023 | Oct 12, 2023 | S | 1,644 | $4.00 | Sale −$6,576 | 365,378 | Yes | Form 4 |