CORTCORCEPT THERAPEUTICS INC
- Market cap
- $9.28B
- as of 2026-10-23
- Latest close
- $85.86
- as of 2026-10-23
- Sector
- Healthcare
- as of 2026-10-24
- Industry
- Biotechnology
- as of 2026-10-24
Cluster
No cluster in the last 90 days under the default rule (14d · ≥2 insiders · all roles).
Form 4 historysince 2023-10-04
Dashed line = amended filing (Form 4/A)
Showing the latest 500 of 933 transactions.
| Insider | Traded | Filed | Type | Shares | Price | Value | Owned after | 10b5-1 plan | Filing |
|---|---|---|---|---|---|---|---|---|---|
| Wilson James N | Oct 15 | Oct 16 | S | 6,654 | $114.48 | Sale −$761,717 | 1,057,889 | Yes | Form 4 |
| Wilson James N | Oct 15 | Oct 16 | S | 3,046 | $115.39 | Sale −$351,476 | 1,054,843 | Yes | Form 4 |
| Wilson James N | Oct 15 | Oct 16 | S | 300 | $116.30 | Sale −$34,889 | 1,054,543 | Yes | Form 4 |
| Maduck SeanSee Remarks | Oct 2 | Oct 5 | M | 24,587 | $8.27 | $203,334 | 34,525 | Yes | Form 4 |
| Maduck SeanSee Remarks | Oct 2 | Oct 5 | S | 15,843 | $116.12 | Sale −$1,839,741 | 18,682 | Yes | Form 4 |
| Maduck SeanSee Remarks | Oct 2 | Oct 5 | S | 8,744 | $116.55 | Sale −$1,019,143 | 9,938 | Yes | Form 4 |
| Maduck SeanSee Remarks | Oct 2 | Oct 5 | M · derivative | 24,587 | $8.27 | $203,334 | 41,986 | Yes | Form 4 |
| Vieira Roberto WandenkolkPresident, Oncology | Oct 2 | Oct 5 | M | 8,333 | $21.63 | $180,243 | 12,279 | Yes | Form 4 |
| Vieira Roberto WandenkolkPresident, Oncology | Oct 2 | Oct 5 | S | 1,100 | $114.52 | Sale −$125,973 | 11,179 | Yes | Form 4 |
| Vieira Roberto WandenkolkPresident, Oncology | Oct 2 | Oct 5 | S | 2,086 | $115.73 | Sale −$241,412 | 9,093 | Yes | Form 4 |
| Vieira Roberto WandenkolkPresident, Oncology | Oct 2 | Oct 5 | S | 5,147 | $116.59 | Sale −$600,063 | 3,946 | Yes | Form 4 |
| Vieira Roberto WandenkolkPresident, Oncology | Oct 2 | Oct 5 | M · derivative | 8,333 | $21.63 | $180,243 | 133,334 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Oct 2 | Oct 5 | M | 3,357 | $13.56 | $45,521 | 9,040 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Oct 2 | Oct 5 | M | 5,833 | $19.26 | $112,344 | 14,873 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Oct 2 | Oct 5 | S | 4,446 | $115.70 | Sale −$514,389 | 10,427 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Oct 2 | Oct 5 | S | 4,744 | $116.54 | Sale −$552,869 | 5,683 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Oct 2 | Oct 5 | M · derivative | 3,357 | $13.56 | $45,521 | not reported | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Oct 2 | Oct 5 | M · derivative | 5,833 | $19.26 | $112,344 | 44,167 | Yes | Form 4 |
| Maduck SeanSee Remarks | Oct 1 | Oct 5 | M | 413 | $8.27 | $3,416 | 10,351 | Yes | Form 4 |
| Maduck SeanSee Remarks | Oct 1 | Oct 5 | S | 413 | $115.54 | Sale −$47,717 | 9,938 | Yes | Form 4 |
| Maduck SeanSee Remarks | Oct 1 | Oct 5 | M · derivative | 413 | $8.27 | $3,416 | 66,573 | Yes | Form 4 |
| Gunn Justin FrederickSee Remarks | Oct 1 | Oct 5 | A · derivative | 100,000 | $114.03 | $11,402,500 | 100,000 | No | Form 4 |
| Lyon Joseph DouglasSee Remarks | Oct 1 | Oct 5 | M | 810 | $13.56 | $10,984 | 6,493 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Oct 1 | Oct 5 | S | 810 | $115.40 | Sale −$93,473 | 5,683 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Oct 1 | Oct 5 | M · derivative | 810 | $13.56 | $10,984 | 3,357 | Yes | Form 4 |
| Robb Gary CharlesChief Business Officer | Sep 24 | Sep 28 | G | 17,100 | $0.00 | $0 | 14,056 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Sep 24 | Sep 28 | G | 5,000 | $0.00 | $0 | 20,571 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Sep 24 | Sep 28 | G | 5,000 | $0.00 | $0 | 20,571 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Sep 17 | Sep 18 | M | 17,493 | $8.27 | $144,667 | 31,156 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Sep 17 | Sep 18 | M · derivative | 17,493 | $8.27 | $144,667 | 182,507 | No | Form 4 |
| Vieira Roberto WandenkolkPresident, Oncology | Sep 16 | Sep 18 | S | 296 | $100.82 | Sale −$29,843 | 3,946 | Yes | Form 4 |
| Wilson James N | Sep 15 | Sep 16 | S | 6,800 | $110.27 | Sale −$749,836 | 1,067,743 | Yes | Form 4 |
| Wilson James N | Sep 15 | Sep 16 | S | 400 | $110.84 | Sale −$44,336 | 1,067,343 | Yes | Form 4 |
| Wilson James N | Sep 15 | Sep 16 | S | 2,800 | $111.70 | Sale −$312,760 | 1,064,543 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Sep 14 | Sep 16 | M | 2,596 | $11.35 | $29,465 | 8,279 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Sep 14 | Sep 16 | M | 7,404 | $13.56 | $100,398 | 15,683 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Sep 14 | Sep 16 | S | 7,812 | $113.32 | Sale −$885,256 | 7,871 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Sep 14 | Sep 16 | S | 2,188 | $114.12 | Sale −$249,695 | 5,683 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Sep 14 | Sep 16 | M · derivative | 2,596 | $11.35 | $29,465 | not reported | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Sep 14 | Sep 16 | M · derivative | 7,404 | $13.56 | $100,398 | 4,167 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Sep 2 | Sep 3 | F | 72 | $113.38 | $8,163 | 5,683 | No | Form 4 |
| Vieira Roberto WandenkolkPresident, Oncology | Sep 2 | Sep 3 | F | 102 | $113.38 | $11,565 | 4,242 | Yes | Form 4 |
| Vieira Roberto WandenkolkPresident, Oncology | Sep 2 | Sep 3 | M | 58,333 | $21.63 | $1,261,743 | 62,575 | Yes | Form 4 |
| Vieira Roberto WandenkolkPresident, Oncology | Sep 2 | Sep 3 | S | 23,600 | $109.35 | Sale −$2,580,660 | 38,975 | Yes | Form 4 |
| Vieira Roberto WandenkolkPresident, Oncology | Sep 2 | Sep 3 | S | 23,770 | $110.70 | Sale −$2,631,339 | 15,205 | Yes | Form 4 |
| Vieira Roberto WandenkolkPresident, Oncology | Sep 2 | Sep 3 | S | 1,537 | $111.37 | Sale −$171,176 | 13,668 | Yes | Form 4 |
| Vieira Roberto WandenkolkPresident, Oncology | Sep 2 | Sep 3 | S | 974 | $112.40 | Sale −$109,478 | 12,694 | Yes | Form 4 |
| Vieira Roberto WandenkolkPresident, Oncology | Sep 2 | Sep 3 | S | 1,606 | $113.72 | Sale −$182,634 | 11,088 | Yes | Form 4 |
| Vieira Roberto WandenkolkPresident, Oncology | Sep 2 | Sep 3 | S | 5,621 | $114.58 | Sale −$644,054 | 5,467 | Yes | Form 4 |
| Vieira Roberto WandenkolkPresident, Oncology | Sep 2 | Sep 3 | S | 1,225 | $115.44 | Sale −$141,414 | 4,242 | Yes | Form 4 |
| Vieira Roberto WandenkolkPresident, Oncology | Sep 2 | Sep 3 | M · derivative | 58,333 | $21.63 | $1,261,743 | 141,667 | Yes | Form 4 |
| Robb Gary CharlesChief Business Officer | Sep 2 | Sep 3 | F | 91 | $113.38 | $10,318 | 13,663 | No | Form 4 |
| Mokari AtabakChief Financial Officer | Sep 2 | Sep 3 | F | 102 | $113.38 | $11,565 | 16,304 | No | Form 4 |
| Maduck SeanSee Remarks | Sep 2 | Sep 3 | F | 117 | $113.38 | $13,265 | 9,938 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Sep 1 | Sep 3 | A | 130 | $113.38 | $14,739 | 5,625 | No | Form 4 |
| Lyon Joseph DouglasSee Remarks | Sep 1 | Sep 3 | A | 130 | $0.00 | $0 | 5,755 | No | Form 4 |
| Vieira Roberto WandenkolkPresident, Oncology | Sep 1 | Sep 3 | A | 138 | $113.38 | $15,646 | 4,206 | Yes | Form 4 |
| Vieira Roberto WandenkolkPresident, Oncology | Sep 1 | Sep 3 | A | 138 | $0.00 | $0 | 4,344 | Yes | Form 4 |
| Robb Gary CharlesChief Business Officer | Sep 1 | Sep 3 | A | 164 | $113.38 | $18,594 | 13,590 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Sep 1 | Sep 3 | A | 164 | $0.00 | $0 | 13,754 | No | Form 4 |
| Mokari AtabakChief Financial Officer | Sep 1 | Sep 3 | A | 138 | $113.38 | $15,646 | 16,268 | No | Form 4 |
| Mokari AtabakChief Financial Officer | Sep 1 | Sep 3 | A | 138 | $0.00 | $0 | 16,406 | No | Form 4 |
| Maduck SeanSee Remarks | Sep 1 | Sep 3 | M | 25,000 | $8.27 | $206,750 | 34,755 | Yes | Form 4 |
| Maduck SeanSee Remarks | Sep 1 | Sep 3 | S | 11,730 | $113.94 | Sale −$1,336,516 | 23,025 | Yes | Form 4 |
| Maduck SeanSee Remarks | Sep 1 | Sep 3 | S | 10,989 | $114.71 | Sale −$1,260,548 | 12,036 | Yes | Form 4 |
| Maduck SeanSee Remarks | Sep 1 | Sep 3 | S | 2,281 | $115.61 | Sale −$263,706 | 9,755 | Yes | Form 4 |
| Maduck SeanSee Remarks | Sep 1 | Sep 3 | A | 150 | $113.38 | $17,007 | 9,905 | Yes | Form 4 |
| Maduck SeanSee Remarks | Sep 1 | Sep 3 | A | 150 | $0.00 | $0 | 10,055 | Yes | Form 4 |
| Maduck SeanSee Remarks | Sep 1 | Sep 3 | M · derivative | 25,000 | $8.27 | $206,750 | 66,986 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Sep 1 | Sep 3 | A | 164 | $113.38 | $18,594 | 4,149 | No | Form 4 |
| Guyer WilliamChief Development Officer | Sep 1 | Sep 3 | A | 164 | $0.00 | $0 | 4,313 | No | Form 4 |
| Park Kimberly | Aug 26 | Aug 28 | M | 30,000 | $13.49 | $404,700 | 30,000 | No | Form 4 |
| Park Kimberly | Aug 26 | Aug 28 | F | 3,315 | $122.09 | $404,728 | 26,685 | No | Form 4 |
| Park Kimberly | Aug 26 | Aug 28 | S | 26,685 | $122.55 | Sale −$3,270,247 | not reported | No | Form 4 |
| Park Kimberly | Aug 26 | Aug 28 | M · derivative | 30,000 | $13.49 | $404,700 | 30,000 | No | Form 4 |
| Maduck SeanSee Remarks | Aug 25 | Aug 27 | M | 30,955 | $11.35 | $351,339 | 40,710 | Yes | Form 4 |
| Maduck SeanSee Remarks | Aug 25 | Aug 27 | S | 25,085 | $125.47 | Sale −$3,147,415 | 15,625 | Yes | Form 4 |
| Maduck SeanSee Remarks | Aug 25 | Aug 27 | S | 5,870 | $126.06 | Sale −$739,972 | 9,755 | Yes | Form 4 |
| Maduck SeanSee Remarks | Aug 25 | Aug 27 | M · derivative | 30,955 | $11.35 | $351,339 | 169,045 | Yes | Form 4 |
| Mahoney David L | Aug 18 | Aug 20 | S | 4,984 | $117.47 | Sale −$585,470 | 1,232,161 | Yes | Form 4 |
| Mahoney David L | Aug 18 | Aug 20 | S | 91,167 | $118.24 | Sale −$10,779,586 | 1,140,994 | Yes | Form 4 |
| Mahoney David L | Aug 18 | Aug 20 | S | 7,055 | $118.88 | Sale −$838,698 | 1,133,939 | Yes | Form 4 |
| Mahoney David L | Aug 18 | Aug 20 | S | 400 | $119.64 | Sale −$47,856 | 1,133,539 | Yes | Form 4 |
| Robb Gary CharlesChief Business Officer | Aug 17 | Aug 18 | G | 125 | $0.00 | $0 | 13,426 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Aug 17 | Aug 18 | S | 10,000 | $116.26 | Sale −$1,162,600 | 39,716 | No | Form 4 |
| Wilson James N | Aug 14 | Aug 18 | S | 3,053 | $110.49 | Sale −$337,326 | 1,081,490 | Yes | Form 4 |
| Wilson James N | Aug 14 | Aug 18 | S | 4,668 | $111.44 | Sale −$520,202 | 1,076,822 | Yes | Form 4 |
| Wilson James N | Aug 14 | Aug 18 | S | 2,279 | $112.64 | Sale −$256,707 | 1,074,543 | Yes | Form 4 |
| Maduck SeanSee Remarks | Aug 14 | Aug 18 | M | 3,664 | $8.27 | $30,301 | 13,419 | Yes | Form 4 |
| Maduck SeanSee Remarks | Aug 14 | Aug 18 | S | 3,664 | $114.49 | Sale −$419,491 | 9,755 | Yes | Form 4 |
| Maduck SeanSee Remarks | Aug 14 | Aug 18 | M · derivative | 3,664 | $8.27 | $30,301 | 91,986 | Yes | Form 4 |
| Robb Gary CharlesChief Business Officer | Aug 12 | Aug 14 | G | 11,530 | $0.00 | $0 | 13,551 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Aug 12 | Aug 14 | G | 3,000 | $0.00 | $0 | 15,571 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Aug 12 | Aug 14 | G | 3,000 | $0.00 | $0 | 15,571 | No | Form 4 |
| Guyer WilliamChief Development Officer | Aug 10 | Aug 12 | M | 16,300 | $21.65 | $352,895 | 20,285 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Aug 10 | Aug 12 | S | 11,530 | $113.18 | Sale −$1,304,965 | 8,755 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Aug 10 | Aug 12 | S | 4,770 | $114.04 | Sale −$543,971 | 3,985 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Aug 10 | Aug 12 | M · derivative | 16,300 | $21.65 | $352,895 | 110,000 | Yes | Form 4 |
| Maduck SeanSee Remarks | Aug 10 | Aug 12 | M | 1,031 | $8.27 | $8,526 | 10,786 | Yes | Form 4 |
| Maduck SeanSee Remarks | Aug 10 | Aug 12 | S | 1,031 | $114.52 | Sale −$118,070 | 9,755 | Yes | Form 4 |
| Maduck SeanSee Remarks | Aug 10 | Aug 12 | M · derivative | 1,031 | $8.27 | $8,526 | 95,650 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Aug 4 | Aug 6 | M | 3,700 | $21.65 | $80,105 | 7,685 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Aug 4 | Aug 6 | S | 3,700 | $113.12 | Sale −$418,544 | 3,985 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Aug 4 | Aug 6 | M · derivative | 3,700 | $21.65 | $80,105 | 126,300 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Aug 3 | Aug 5 | S | 1,540 | $114.16 | Sale −$175,806 | 5,495 | No | Form 4 |
| Maduck SeanSee Remarks | Aug 3 | Aug 5 | M | 20,305 | $8.27 | $167,922 | 30,060 | Yes | Form 4 |
| Maduck SeanSee Remarks | Aug 3 | Aug 5 | S | 20,305 | $114.70 | Sale −$2,328,984 | 9,755 | Yes | Form 4 |
| Maduck SeanSee Remarks | Aug 3 | Aug 5 | M · derivative | 20,305 | $8.27 | $167,922 | 96,681 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 30 | Aug 3 | M | 80,000 | $23.06 | $1,844,800 | 96,130 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 30 | Aug 3 | S | 4,200 | $105.54 | Sale −$443,268 | 91,930 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 30 | Aug 3 | S | 8,956 | $106.96 | Sale −$957,934 | 82,974 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 30 | Aug 3 | S | 400 | $108.46 | Sale −$43,384 | 82,574 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 30 | Aug 3 | S | 2,202 | $110.03 | Sale −$242,286 | 80,372 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 30 | Aug 3 | S | 600 | $110.95 | Sale −$66,570 | 79,772 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 30 | Aug 3 | S | 4,700 | $113.18 | Sale −$531,946 | 75,072 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 30 | Aug 3 | S | 15,477 | $114.96 | Sale −$1,779,236 | 59,595 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 30 | Aug 3 | S | 14,222 | $115.87 | Sale −$1,647,903 | 45,373 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 30 | Aug 3 | S | 7,089 | $116.96 | Sale −$829,129 | 38,284 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 30 | Aug 3 | S | 8,267 | $117.93 | Sale −$974,927 | 30,017 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 30 | Aug 3 | S | 4,783 | $118.73 | Sale −$567,886 | 25,234 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 30 | Aug 3 | S | 8,103 | $119.95 | Sale −$971,955 | 17,131 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 30 | Aug 3 | S | 1,001 | $120.67 | Sale −$120,791 | 16,130 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 30 | Aug 3 | M · derivative | 80,000 | $23.06 | $1,844,800 | 95,833 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 15 | Jul 17 | M | 15,833 | $19.26 | $304,944 | 31,963 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 15 | Jul 17 | M | 24,167 | $23.06 | $557,291 | 56,130 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 15 | Jul 17 | S | 7,919 | $86.78 | Sale −$687,211 | 48,211 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 15 | Jul 17 | S | 28,460 | $87.89 | Sale −$2,501,349 | 19,751 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 15 | Jul 17 | S | 3,520 | $88.30 | Sale −$310,816 | 16,231 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 15 | Jul 17 | S | 101 | $89.43 | Sale −$9,032 | 16,130 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 15 | Jul 17 | M · derivative | 15,833 | $19.26 | $304,944 | 4,167 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jul 15 | Jul 17 | M · derivative | 24,167 | $23.06 | $557,291 | 175,833 | Yes | Form 4 |
| Wilson James N | Jul 15 | Jul 17 | S | 1,079 | $86.78 | Sale −$93,636 | 1,093,464 | Yes | Form 4 |
| Wilson James N | Jul 15 | Jul 17 | S | 3,969 | $87.74 | Sale −$348,240 | 1,089,495 | Yes | Form 4 |
| Wilson James N | Jul 15 | Jul 17 | S | 2,974 | $88.81 | Sale −$264,121 | 1,086,521 | Yes | Form 4 |
| Wilson James N | Jul 15 | Jul 17 | S | 1,978 | $89.49 | Sale −$177,011 | 1,084,543 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jul 7 | Jul 8 | M | 20,000 | $21.65 | $433,000 | 23,985 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jul 7 | Jul 8 | S | 19,048 | $93.11 | Sale −$1,773,559 | 4,937 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jul 7 | Jul 8 | S | 952 | $93.54 | Sale −$89,050 | 3,985 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jul 7 | Jul 8 | M · derivative | 20,000 | $21.65 | $433,000 | 130,000 | Yes | Form 4 |
| Robb Gary CharlesChief Business Officer | May 27 | Jul 8 | G | 600 | $0.00 | $0 | 25,081 | No | Form 4 |
| Maduck SeanSee Remarks | Jul 1 | Jul 6 | M | 25,000 | $8.27 | $206,750 | 34,755 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jul 1 | Jul 6 | S | 11,024 | $87.33 | Sale −$962,726 | 23,731 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jul 1 | Jul 6 | S | 2,801 | $88.51 | Sale −$247,917 | 20,930 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jul 1 | Jul 6 | S | 11,175 | $89.31 | Sale −$998,039 | 9,755 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jul 1 | Jul 6 | M · derivative | 25,000 | $8.27 | $206,750 | 116,986 | Yes | Form 4 |
| Mahoney David L | Jun 17 | Jun 18 | S | 20,000 | $84.53 | Sale −$1,690,600 | 26,147 | No | Form 4 |
| Wilson James N | Jun 16 | Jun 18 | S | 4,177 | $82.69 | Sale −$345,396 | 1,100,366 | Yes | Form 4 |
| Wilson James N | Jun 16 | Jun 18 | S | 5,823 | $83.57 | Sale −$486,628 | 1,094,543 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jun 15 | Jun 17 | M | 40,000 | $19.26 | $770,400 | 56,130 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jun 15 | Jun 17 | S | 9,434 | $80.02 | Sale −$754,909 | 46,696 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jun 15 | Jun 17 | S | 11,081 | $80.94 | Sale −$896,896 | 35,615 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jun 15 | Jun 17 | S | 19,483 | $81.81 | Sale −$1,593,904 | 16,132 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jun 15 | Jun 17 | S | 2 | $82.45 | Sale −$165 | 16,130 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jun 15 | Jun 17 | M · derivative | 40,000 | $19.26 | $770,400 | 20,000 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jun 2 | Jun 4 | M | 20,000 | $21.65 | $433,000 | 23,985 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jun 2 | Jun 4 | S | 20,000 | $70.60 | Sale −$1,412,000 | 3,985 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jun 2 | Jun 4 | M · derivative | 20,000 | $21.65 | $433,000 | 150,000 | Yes | Form 4 |
| Robb Gary CharlesChief Business Officer | Jun 2 | Jun 3 | F | 358 | $70.44 | $25,218 | 25,681 | No | Form 4 |
| Mokari AtabakChief Financial Officer | Jun 2 | Jun 3 | F | 395 | $70.44 | $27,824 | 16,130 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jun 2 | Jun 3 | F | 452 | $70.44 | $31,839 | 9,755 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Jun 2 | Jun 3 | F | 269 | $70.44 | $18,948 | 7,035 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Jun 1 | Jun 3 | A | 776 | $70.44 | $54,661 | 25,263 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Jun 1 | Jun 3 | A | 776 | $0.00 | $0 | 26,039 | No | Form 4 |
| Mokari AtabakChief Financial Officer | Jun 1 | Jun 3 | M | 40,000 | $19.26 | $770,400 | 55,257 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jun 1 | Jun 3 | S | 40,000 | $70.00 | Sale −$2,800,000 | 15,257 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jun 1 | Jun 3 | A | 634 | $70.44 | $44,659 | 15,891 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jun 1 | Jun 3 | A | 634 | $0.00 | $0 | 16,525 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jun 1 | Jun 3 | M · derivative | 40,000 | $19.26 | $770,400 | 60,000 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jun 1 | Jun 3 | M | 25,000 | $8.27 | $206,750 | 33,977 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jun 1 | Jun 3 | S | 21,069 | $70.11 | Sale −$1,477,148 | 12,908 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jun 1 | Jun 3 | S | 3,931 | $70.75 | Sale −$278,118 | 8,977 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jun 1 | Jun 3 | A | 615 | $70.44 | $43,321 | 9,592 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jun 1 | Jun 3 | A | 615 | $0.00 | $0 | 10,207 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jun 1 | Jun 3 | M · derivative | 25,000 | $8.27 | $206,750 | 141,986 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jun 1 | Jun 3 | A | 877 | $70.44 | $61,776 | 3,108 | No | Form 4 |
| Guyer WilliamChief Development Officer | Jun 1 | Jun 3 | A | 877 | $0.00 | $0 | 3,985 | No | Form 4 |
| Lyon Joseph DouglasSee Remarks | Jun 1 | Jun 3 | A | 537 | $70.44 | $37,826 | 6,767 | No | Form 4 |
| Lyon Joseph DouglasSee Remarks | Jun 1 | Jun 3 | A | 537 | $0.00 | $0 | 7,304 | No | Form 4 |
| Belanoff Joseph KChief Executive Officer | Jun 1 | Jun 2 | S | 12,837 | $69.74 | Sale −$895,252 | 2,565,489 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | May 29 | Jun 2 | G | 300,000 | $0.00 | $0 | 2,578,326 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | May 29 | Jun 2 | G | 150,000 | $0.00 | $0 | 150,000 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | May 29 | Jun 2 | G | 150,000 | $0.00 | $0 | 150,000 | Yes | Form 4 |
| Wilson James N | May 27 | May 29 | G | 892,056 | $0.00 | $0 | 9,011 | No | Form 4 |
| Wilson James N | May 27 | May 29 | G | 9,011 | $0.00 | $0 | not reported | No | Form 4 |
| Wilson James N | May 27 | May 29 | G | 9,011 | $0.00 | $0 | 1,104,543 | No | Form 4 |
| Maduck SeanSee Remarks | May 27 | May 29 | M | 75,000 | $8.27 | $620,250 | 83,977 | Yes | Form 4 |
| Maduck SeanSee Remarks | May 27 | May 29 | S | 54,575 | $65.37 | Sale −$3,567,568 | 29,402 | Yes | Form 4 |
| Maduck SeanSee Remarks | May 27 | May 29 | S | 20,425 | $66.16 | Sale −$1,351,318 | 8,977 | Yes | Form 4 |
| Maduck SeanSee Remarks | May 27 | May 29 | M · derivative | 75,000 | $8.27 | $620,250 | 166,986 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | May 27 | May 29 | S | 5,000 | $65.00 | Sale −$325,000 | 6,230 | No | Form 4 |
| Park Kimberly | May 21 | May 26 | A · derivative | 12,500 | $59.69 | $746,125 | 12,500 | No | Form 4 |
| Mahoney David L | May 21 | May 26 | A · derivative | 12,500 | $59.69 | $746,125 | 12,500 | No | Form 4 |
| Murray Joshua M. | May 21 | May 26 | A · derivative | 12,500 | $59.69 | $746,125 | 12,500 | No | Form 4 |
| Swisher Daniel N JR | May 21 | May 26 | A · derivative | 12,500 | $59.69 | $746,125 | 12,500 | No | Form 4 |
| Wilson James N | May 21 | May 26 | A · derivative | 12,500 | $59.69 | $746,125 | 12,500 | No | Form 4 |
| Alton Gregg H | May 21 | May 26 | A · derivative | 12,500 | $59.69 | $746,125 | 12,500 | No | Form 4 |
| Baker G Leonard Jr | May 21 | May 26 | A · derivative | 12,500 | $59.69 | $746,125 | 12,500 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | May 13 | May 15 | G | 5,300 | $0.00 | $0 | 24,487 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | May 13 | May 15 | G | 1,000 | $0.00 | $0 | 12,571 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | May 13 | May 15 | G | 1,000 | $0.00 | $0 | 12,571 | No | Form 4 |
| Guyer WilliamChief Development Officer | May 5 | May 7 | M | 20,000 | $21.65 | $433,000 | 22,231 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | May 5 | May 7 | S | 20,000 | $51.83 | Sale −$1,036,600 | 2,231 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | May 5 | May 7 | M · derivative | 20,000 | $21.65 | $433,000 | 170,000 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | May 1 | May 5 | S | 40,000 | $50.10 | Sale −$2,004,000 | 2,878,326 | Yes | Form 4 |
| Wilson James N | Apr 22 | Apr 24 | G | 2,000 | $0.00 | $0 | 1,095,532 | No | Form 4 |
| Guyer WilliamChief Development Officer | Apr 7 | Apr 8 | M | 20,000 | $21.65 | $433,000 | 22,231 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Apr 7 | Apr 8 | S | 20,000 | $40.97 | Sale −$819,400 | 2,231 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Apr 7 | Apr 8 | M · derivative | 20,000 | $21.65 | $433,000 | 190,000 | Yes | Form 4 |
| Wilson James N | Apr 6 | Apr 8 | G | 5,000 | $0.00 | $0 | 1,097,532 | No | Form 4 |
| Belanoff Joseph KChief Executive Officer | Mar 25 | Mar 27 | S | 26,198 | $50.07 | Sale −$1,311,734 | 2,918,326 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Mar 20 | Mar 24 | M | 11,767 | $21.65 | $254,756 | 13,998 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Mar 20 | Mar 24 | S | 11,767 | $36.01 | Sale −$423,730 | 2,231 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Mar 20 | Mar 24 | M · derivative | 11,767 | $21.65 | $254,756 | 210,000 | Yes | Form 4 |
| Wilson James N | Mar 20 | Mar 24 | G | 4,000 | $0.00 | $0 | 1,102,532 | No | Form 4 |
| Baker G Leonard Jr | Mar 17 | Mar 19 | P | 75,782 | $33.00 | Purchase +$2,500,806 | 1,122,413 | No | Form 4 |
| Baker G Leonard Jr | Mar 17 | Mar 19 | P | 24,218 | $33.56 | Purchase +$812,756 | 1,146,631 | No | Form 4 |
| Mahoney David L | Mar 13 | Mar 17 | M | 30,000 | $5.86 | $175,800 | 30,000 | No | Form 4 |
| Mahoney David L | Mar 13 | Mar 17 | F | 5,469 | $32.15 | $175,828 | 24,531 | No | Form 4 |
| Mahoney David L | Mar 13 | Mar 17 | G | 24,531 | $0.00 | $0 | not reported | No | Form 4 |
| Mahoney David L | Mar 13 | Mar 17 | J | 24,531 | $0.00 | $0 | 1,237,145 | No | Form 4 |
| Mahoney David L | Mar 13 | Mar 17 | M · derivative | 30,000 | $5.86 | $175,800 | not reported | No | Form 4 |
| Wilson James N | Mar 13 | Mar 17 | G | 28,000 | $0.00 | $0 | 1,106,532 | No | Form 4 |
| Guyer WilliamChief Development Officer | Mar 4 | Mar 6 | M | 8,233 | $21.65 | $178,244 | 10,464 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Mar 4 | Mar 6 | S | 8,233 | $35.99 | Sale −$296,306 | 2,231 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Mar 4 | Mar 6 | M · derivative | 8,233 | $21.65 | $178,244 | 221,767 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Mar 3 | Mar 4 | F | 96 | $35.97 | $3,453 | 15,257 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Mar 3 | Mar 4 | F | 121 | $35.97 | $4,352 | 79,503 | No | Form 4 |
| Maduck SeanSee Remarks | Mar 3 | Mar 4 | F | 110 | $35.97 | $3,957 | 8,977 | No | Form 4 |
| Lyon Joseph DouglasSee Remarks | Mar 3 | Mar 4 | F | 89 | $35.97 | $3,201 | 11,230 | No | Form 4 |
| Mokari AtabakChief Financial Officer | Mar 2 | Mar 4 | A | 397 | $35.97 | $14,280 | 14,956 | No | Form 4 |
| Mokari AtabakChief Financial Officer | Mar 2 | Mar 4 | A | 397 | $0.00 | $0 | 15,353 | No | Form 4 |
| Guyer WilliamChief Development Officer | Mar 2 | Mar 4 | A | 498 | $35.97 | $17,913 | 1,733 | No | Form 4 |
| Guyer WilliamChief Development Officer | Mar 2 | Mar 4 | A | 498 | $0.00 | $0 | 2,231 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Mar 2 | Mar 4 | A | 499 | $35.97 | $17,949 | 79,125 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Mar 2 | Mar 4 | A | 499 | $0.00 | $0 | 79,624 | No | Form 4 |
| Maduck SeanSee Remarks | Mar 2 | Mar 4 | A | 454 | $35.97 | $16,330 | 8,633 | No | Form 4 |
| Maduck SeanSee Remarks | Mar 2 | Mar 4 | A | 454 | $0.00 | $0 | 9,087 | No | Form 4 |
| Lyon Joseph DouglasSee Remarks | Mar 2 | Mar 4 | A | 398 | $35.97 | $14,316 | 10,921 | No | Form 4 |
| Lyon Joseph DouglasSee Remarks | Mar 2 | Mar 4 | A | 398 | $0.00 | $0 | 11,319 | No | Form 4 |
| Guyer WilliamChief Development Officer | Feb 27 | Mar 3 | A · derivative | 140,000 | $35.70 | $4,998,000 | 140,000 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Feb 27 | Mar 3 | A · derivative | 140,000 | $35.70 | $4,998,000 | 140,000 | No | Form 4 |
| Hunt HazelChief Scientific Officer | Feb 27 | Mar 3 | A · derivative | 140,000 | $35.70 | $4,998,000 | 140,000 | No | Form 4 |
| Maduck SeanSee Remarks | Feb 27 | Mar 3 | A · derivative | 140,000 | $35.70 | $4,998,000 | 140,000 | No | Form 4 |
| Mokari AtabakChief Financial Officer | Feb 27 | Mar 3 | A · derivative | 140,000 | $35.70 | $4,998,000 | 140,000 | No | Form 4 |
| Belanoff Joseph KChief Executive Officer | Feb 27 | Mar 3 | A · derivative | 460,000 | $35.70 | $16,422,000 | 460,000 | No | Form 4 |
| Lyon Joseph DouglasSee Remarks | Feb 27 | Mar 3 | A · derivative | 140,000 | $35.70 | $4,998,000 | 140,000 | No | Form 4 |
| Wilson James N | Feb 24 | Feb 26 | M | 100,000 | $3.88 | $388,000 | 100,000 | No | Form 4 |
| Wilson James N | Feb 24 | Feb 26 | F | 10,636 | $36.48 | $388,001 | 89,364 | No | Form 4 |
| Wilson James N | Feb 24 | Feb 26 | G | 89,364 | $0.00 | $0 | not reported | No | Form 4 |
| Wilson James N | Feb 24 | Feb 26 | J | 89,364 | $0.00 | $0 | 1,134,532 | No | Form 4 |
| Wilson James N | Feb 24 | Feb 26 | M · derivative | 100,000 | $3.88 | $388,000 | not reported | No | Form 4 |
| Maduck SeanSee Remarks | Jan 8 | Feb 13 | G | 20,570 | $0.00 | $0 | 39,147 | No | Form 4 |
| Maduck SeanSee Remarks | Jan 8 | Feb 13 | J | 20,570 | $0.00 | $0 | 20,570 | No | Form 4 |
| Maduck SeanSee Remarks | Jan 8 | Feb 13 | G | 34,000 | $0.00 | $0 | 5,147 | No | Form 4 |
| Maduck SeanSee Remarks | Jan 8 | Feb 13 | J | 34,000 | $0.00 | $0 | 34,000 | No | Form 4 |
| Hunt HazelChief Scientific Officer | Feb 9 | Feb 11 | M | 150,000 | $3.88 | $582,000 | 333,405 | No | Form 4 |
| Hunt HazelChief Scientific Officer | Feb 9 | Feb 11 | F | 77,968 | $41.31 | $3,220,858 | 255,437 | No | Form 4 |
| Hunt HazelChief Scientific Officer | Feb 9 | Feb 11 | M · derivative | 150,000 | $3.88 | $582,000 | not reported | No | Form 4 |
| Guyer WilliamChief Development Officer | Feb 3 | Feb 5 | M | 20,000 | $21.65 | $433,000 | 21,235 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Feb 3 | Feb 5 | S | 20,000 | $40.87 | Sale −$817,400 | 1,235 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Feb 3 | Feb 5 | M · derivative | 20,000 | $21.65 | $433,000 | 230,000 | Yes | Form 4 |
| Baker G Leonard Jr | Jan 27 | Jan 29 | M | 30,000 | $5.86 | $175,800 | 985,262 | No | Form 4 |
| Baker G Leonard Jr | Jan 27 | Jan 29 | M | 30,000 | $12.13 | $363,900 | 1,015,262 | No | Form 4 |
| Baker G Leonard Jr | Jan 27 | Jan 29 | M | 25,000 | $14.08 | $352,000 | 1,040,262 | No | Form 4 |
| Baker G Leonard Jr | Jan 27 | Jan 29 | M | 25,000 | $10.50 | $262,500 | 1,065,262 | No | Form 4 |
| Baker G Leonard Jr | Jan 27 | Jan 29 | M | 30,000 | $15.15 | $454,500 | 1,095,262 | No | Form 4 |
| Baker G Leonard Jr | Jan 27 | Jan 29 | M · derivative | 30,000 | $5.86 | $175,800 | not reported | No | Form 4 |
| Baker G Leonard Jr | Jan 27 | Jan 29 | M · derivative | 30,000 | $12.13 | $363,900 | not reported | No | Form 4 |
| Baker G Leonard Jr | Jan 27 | Jan 29 | M · derivative | 25,000 | $14.08 | $352,000 | not reported | No | Form 4 |
| Baker G Leonard Jr | Jan 27 | Jan 29 | M · derivative | 25,000 | $10.50 | $262,500 | not reported | No | Form 4 |
| Baker G Leonard Jr | Jan 27 | Jan 29 | M · derivative | 30,000 | $15.15 | $454,500 | not reported | No | Form 4 |
| Guyer WilliamChief Development Officer | Jan 6 | Jan 8 | M | 20,000 | $21.65 | $433,000 | 21,235 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jan 6 | Jan 8 | S | 20,000 | $35.18 | Sale −$703,600 | 1,235 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jan 6 | Jan 8 | M · derivative | 20,000 | $21.65 | $433,000 | 250,000 | Yes | Form 4 |
| Baker G Leonard Jr | Jan 1 | Jan 5 | G | 0 | $0.00 | $0 | 3,308,303 | No | Form 4 |
| Belanoff Joseph KChief Executive Officer | Dec 24, 2025 | Dec 29, 2025 | M | 550,000 | $3.88 | $2,134,000 | 550,000 | No | Form 4 |
| Belanoff Joseph KChief Executive Officer | Dec 24, 2025 | Dec 29, 2025 | F | 306,846 | $83.59 | $25,649,257 | 243,154 | No | Form 4 |
| Belanoff Joseph KChief Executive Officer | Dec 24, 2025 | Dec 29, 2025 | G | 243,154 | $0.00 | $0 | not reported | No | Form 4 |
| Belanoff Joseph KChief Executive Officer | Dec 24, 2025 | Dec 29, 2025 | J | 243,154 | $0.00 | $0 | 2,944,524 | No | Form 4 |
| Belanoff Joseph KChief Executive Officer | Dec 24, 2025 | Dec 29, 2025 | M · derivative | 550,000 | $3.88 | $2,134,000 | not reported | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Dec 24, 2025 | Dec 29, 2025 | M | 145,000 | $3.88 | $562,600 | 158,910 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Dec 24, 2025 | Dec 29, 2025 | F | 80,284 | $83.59 | $6,710,940 | 78,626 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Dec 24, 2025 | Dec 29, 2025 | M · derivative | 145,000 | $3.88 | $562,600 | not reported | No | Form 4 |
| Wilson James N | Dec 12, 2025 | Dec 16, 2025 | G | 400,000 | $0.00 | $0 | 1,045,168 | No | Form 4 |
| Wilson James N | Dec 12, 2025 | Dec 16, 2025 | J | 200,000 | $0.00 | $0 | 200,000 | No | Form 4 |
| Wilson James N | Dec 12, 2025 | Dec 16, 2025 | J | 200,000 | $0.00 | $0 | 200,000 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Dec 2, 2025 | Dec 3, 2025 | F | 148 | $79.78 | $11,807 | 13,910 | No | Form 4 |
| Mokari AtabakChief Financial Officer | Dec 2, 2025 | Dec 3, 2025 | F | 118 | $79.78 | $9,414 | 14,559 | No | Form 4 |
| Lyon Joseph DouglasSee Remarks | Dec 2, 2025 | Dec 3, 2025 | F | 110 | $79.78 | $8,776 | 10,523 | Yes | Form 4 |
| Maduck SeanSee Remarks | Dec 2, 2025 | Dec 3, 2025 | F | 135 | $79.78 | $10,770 | 8,179 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Dec 2, 2025 | Dec 3, 2025 | G | 787 | $0.00 | $0 | not reported | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Dec 2, 2025 | Dec 3, 2025 | J | 787 | $0.00 | $0 | 1,235 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Dec 2, 2025 | Dec 3, 2025 | M | 20,000 | $21.65 | $433,000 | 21,235 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Dec 2, 2025 | Dec 3, 2025 | S | 19,360 | $80.05 | Sale −$1,549,768 | 1,875 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Dec 2, 2025 | Dec 3, 2025 | S | 640 | $80.88 | Sale −$51,763 | 1,235 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Dec 2, 2025 | Dec 3, 2025 | M · derivative | 20,000 | $21.65 | $433,000 | 270,000 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | Dec 1, 2025 | Dec 3, 2025 | S | 40,000 | $79.77 | Sale −$3,190,800 | 2,701,370 | Yes | Form 4 |
| Robb Gary CharlesChief Business Officer | Dec 1, 2025 | Dec 3, 2025 | A | 224 | $79.78 | $17,871 | 13,834 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Dec 1, 2025 | Dec 3, 2025 | A | 224 | $0.00 | $0 | 14,058 | No | Form 4 |
| Mokari AtabakChief Financial Officer | Dec 1, 2025 | Dec 3, 2025 | A | 178 | $79.78 | $14,201 | 14,499 | No | Form 4 |
| Mokari AtabakChief Financial Officer | Dec 1, 2025 | Dec 3, 2025 | A | 178 | $0.00 | $0 | 14,677 | No | Form 4 |
| Lyon Joseph DouglasSee Remarks | Dec 1, 2025 | Dec 3, 2025 | M | 5,000 | $13.56 | $67,800 | 15,277 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Dec 1, 2025 | Dec 3, 2025 | S | 5,000 | $79.53 | Sale −$397,650 | 10,277 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Dec 1, 2025 | Dec 3, 2025 | A | 178 | $79.78 | $14,201 | 10,455 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Dec 1, 2025 | Dec 3, 2025 | A | 178 | $0.00 | $0 | 10,633 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Dec 1, 2025 | Dec 3, 2025 | M · derivative | 5,000 | $13.56 | $67,800 | 11,571 | Yes | Form 4 |
| Maduck SeanSee Remarks | Dec 1, 2025 | Dec 3, 2025 | M | 20,000 | $8.27 | $165,400 | 27,904 | Yes | Form 4 |
| Maduck SeanSee Remarks | Dec 1, 2025 | Dec 3, 2025 | S | 20,000 | $79.52 | Sale −$1,590,400 | 7,904 | Yes | Form 4 |
| Maduck SeanSee Remarks | Dec 1, 2025 | Dec 3, 2025 | A | 205 | $79.78 | $16,355 | 8,109 | Yes | Form 4 |
| Maduck SeanSee Remarks | Dec 1, 2025 | Dec 3, 2025 | A | 205 | $0.00 | $0 | 8,314 | Yes | Form 4 |
| Maduck SeanSee Remarks | Dec 1, 2025 | Dec 3, 2025 | M · derivative | 20,000 | $8.27 | $165,400 | 241,986 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Dec 1, 2025 | Dec 3, 2025 | A | 224 | $79.78 | $17,871 | 224 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Dec 1, 2025 | Dec 3, 2025 | A | 224 | $0.00 | $0 | 448 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Nov 25, 2025 | Dec 3, 20254/A | S | 4,500 | $80.90 | Sale −$364,050 | 787 | No | Form 4/A |
| Guyer WilliamChief Development Officer | Nov 17, 2025 | Dec 3, 20254/A | G | 5,287 | $0.00 | $0 | not reported | No | Form 4/A |
| Guyer WilliamChief Development Officer | Nov 17, 2025 | Dec 3, 20254/A | J | 5,287 | $0.00 | $0 | 5,287 | No | Form 4/A |
| Guyer WilliamChief Development Officer | Nov 25, 2025 | Nov 26, 2025 | S | 4,500 | $80.90 | Sale −$364,050 | 787 | No | Form 4 |
| Guyer WilliamChief Development Officer | Nov 5, 2025 | Nov 7, 2025 | M | 20,000 | $21.65 | $433,000 | 25,287 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Nov 5, 2025 | Nov 7, 2025 | S | 6,536 | $74.75 | Sale −$488,566 | 18,751 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Nov 5, 2025 | Nov 7, 2025 | S | 13,164 | $75.64 | Sale −$995,725 | 5,587 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Nov 5, 2025 | Nov 7, 2025 | S | 300 | $76.28 | Sale −$22,884 | 5,287 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Nov 5, 2025 | Nov 7, 2025 | M · derivative | 20,000 | $21.65 | $433,000 | 290,000 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | Nov 5, 2025 | Nov 5, 2025 | S | 14,355 | $74.20 | Sale −$1,065,141 | 2,755,797 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | Nov 5, 2025 | Nov 5, 2025 | S | 10,837 | $75.14 | Sale −$814,292 | 2,744,960 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | Nov 5, 2025 | Nov 5, 2025 | S | 3,590 | $75.98 | Sale −$272,768 | 2,741,370 | Yes | Form 4 |
| Maduck SeanSee Remarks | Nov 3, 2025 | Nov 5, 2025 | M | 20,000 | $8.27 | $165,400 | 27,904 | Yes | Form 4 |
| Maduck SeanSee Remarks | Nov 3, 2025 | Nov 5, 2025 | S | 20,000 | $73.99 | Sale −$1,479,800 | 7,904 | Yes | Form 4 |
| Maduck SeanSee Remarks | Nov 3, 2025 | Nov 5, 2025 | M · derivative | 20,000 | $8.27 | $165,400 | 261,986 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | Nov 3, 2025 | Nov 5, 2025 | S | 11,218 | $74.08 | Sale −$831,029 | 2,770,152 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Nov 3, 2025 | Nov 5, 2025 | M | 5,000 | $13.56 | $67,800 | 15,277 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Nov 3, 2025 | Nov 5, 2025 | S | 5,000 | $73.65 | Sale −$368,250 | 10,277 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Nov 3, 2025 | Nov 5, 2025 | M · derivative | 5,000 | $13.56 | $67,800 | 16,571 | Yes | Form 4 |
| Swisher Daniel N JR | Oct 10, 2025 | Oct 15, 2025 | M | 2,200 | $14.08 | $30,976 | 2,200 | Yes | Form 4 |
| Swisher Daniel N JR | Oct 10, 2025 | Oct 15, 2025 | S | 2,200 | $87.54 | Sale −$192,588 | not reported | Yes | Form 4 |
| Swisher Daniel N JR | Oct 10, 2025 | Oct 15, 2025 | M · derivative | 2,200 | $14.08 | $30,976 | 1,100 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Oct 7, 2025 | Oct 9, 2025 | M | 20,000 | $21.65 | $433,000 | 25,287 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Oct 7, 2025 | Oct 9, 2025 | S | 20,000 | $89.94 | Sale −$1,798,800 | 5,287 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Oct 7, 2025 | Oct 9, 2025 | M · derivative | 20,000 | $21.65 | $433,000 | 310,000 | Yes | Form 4 |
| Maduck SeanSee Remarks | Oct 1, 2025 | Oct 3, 2025 | M | 1,986 | $5.05 | $10,029 | 9,890 | Yes | Form 4 |
| Maduck SeanSee Remarks | Oct 1, 2025 | Oct 3, 2025 | M | 18,014 | $8.27 | $148,976 | 27,904 | Yes | Form 4 |
| Maduck SeanSee Remarks | Oct 1, 2025 | Oct 3, 2025 | S | 959 | $83.73 | Sale −$80,297 | 26,945 | Yes | Form 4 |
| Maduck SeanSee Remarks | Oct 1, 2025 | Oct 3, 2025 | S | 16,394 | $85.06 | Sale −$1,394,474 | 10,551 | Yes | Form 4 |
| Maduck SeanSee Remarks | Oct 1, 2025 | Oct 3, 2025 | S | 2,647 | $85.58 | Sale −$226,530 | 7,904 | Yes | Form 4 |
| Maduck SeanSee Remarks | Oct 1, 2025 | Oct 3, 2025 | M · derivative | 1,986 | $5.05 | $10,029 | not reported | Yes | Form 4 |
| Maduck SeanSee Remarks | Oct 1, 2025 | Oct 3, 2025 | M · derivative | 18,014 | $8.27 | $148,976 | 281,986 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Oct 1, 2025 | Oct 3, 2025 | M | 5,000 | $13.56 | $67,800 | 15,277 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Oct 1, 2025 | Oct 3, 2025 | S | 927 | $83.71 | Sale −$77,599 | 14,350 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Oct 1, 2025 | Oct 3, 2025 | S | 3,473 | $84.92 | Sale −$294,927 | 10,877 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Oct 1, 2025 | Oct 3, 2025 | S | 600 | $85.39 | Sale −$51,234 | 10,277 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Oct 1, 2025 | Oct 3, 2025 | M · derivative | 5,000 | $13.56 | $67,800 | 21,571 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | Oct 1, 2025 | Oct 3, 2025 | S | 5,616 | $84.29 | Sale −$473,373 | 2,815,754 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | Oct 1, 2025 | Oct 3, 2025 | S | 31,190 | $85.16 | Sale −$2,656,140 | 2,784,564 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | Oct 1, 2025 | Oct 3, 2025 | S | 3,194 | $85.67 | Sale −$273,630 | 2,781,370 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Sep 19, 2025 | Sep 23, 2025 | G | 200 | $0.00 | $0 | 5,287 | No | Form 4 |
| Swisher Daniel N JR | Sep 10, 2025 | Sep 11, 2025 | M | 2,200 | $14.08 | $30,976 | 2,200 | Yes | Form 4 |
| Swisher Daniel N JR | Sep 10, 2025 | Sep 11, 2025 | S | 2,200 | $72.45 | Sale −$159,390 | not reported | Yes | Form 4 |
| Swisher Daniel N JR | Sep 10, 2025 | Sep 11, 2025 | M · derivative | 2,200 | $14.08 | $30,976 | 3,300 | Yes | Form 4 |
| Cannon Gillian | Sep 10, 2025 | Sep 11, 2025 | G | 7,393 | $0.00 | $0 | not reported | No | Form 4 |
| Cannon Gillian | Sep 4, 2025 | Sep 8, 2025 | M | 11,000 | $22.99 | $252,890 | 11,000 | No | Form 4 |
| Cannon Gillian | Sep 4, 2025 | Sep 8, 2025 | F | 3,607 | $70.13 | $252,959 | 7,393 | No | Form 4 |
| Cannon Gillian | Sep 4, 2025 | Sep 8, 2025 | M · derivative | 11,000 | $22.99 | $252,890 | 49,000 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Sep 3, 2025 | Sep 4, 2025 | F | 256 | $71.38 | $18,273 | 13,610 | No | Form 4 |
| Mokari AtabakChief Financial Officer | Sep 3, 2025 | Sep 4, 2025 | F | 144 | $71.38 | $10,279 | 14,321 | No | Form 4 |
| Maduck SeanSee Remarks | Sep 3, 2025 | Sep 4, 2025 | F | 233 | $71.38 | $16,632 | 7,904 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Sep 3, 2025 | Sep 4, 2025 | F | 189 | $71.38 | $13,491 | 10,277 | Yes | Form 4 |
| Robb Gary CharlesChief Business Officer | Sep 2, 2025 | Sep 4, 2025 | A | 251 | $71.38 | $17,916 | 13,615 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Sep 2, 2025 | Sep 4, 2025 | A | 251 | $0.00 | $0 | 13,866 | No | Form 4 |
| Mokari AtabakChief Financial Officer | Sep 2, 2025 | Sep 4, 2025 | A | 200 | $71.38 | $14,276 | 14,265 | No | Form 4 |
| Mokari AtabakChief Financial Officer | Sep 2, 2025 | Sep 4, 2025 | A | 200 | $0.00 | $0 | 14,465 | No | Form 4 |
| Belanoff Joseph KChief Executive Officer | Sep 2, 2025 | Sep 4, 2025 | S | 39,300 | $70.52 | Sale −$2,771,436 | 2,822,070 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | Sep 2, 2025 | Sep 4, 2025 | S | 700 | $71.01 | Sale −$49,707 | 2,821,370 | Yes | Form 4 |
| Maduck SeanSee Remarks | Sep 2, 2025 | Sep 4, 2025 | M | 20,000 | $5.05 | $101,000 | 27,681 | Yes | Form 4 |
| Maduck SeanSee Remarks | Sep 2, 2025 | Sep 4, 2025 | S | 15,070 | $70.38 | Sale −$1,060,627 | 12,611 | Yes | Form 4 |
| Maduck SeanSee Remarks | Sep 2, 2025 | Sep 4, 2025 | S | 4,930 | $70.84 | Sale −$349,241 | 7,681 | Yes | Form 4 |
| Maduck SeanSee Remarks | Sep 2, 2025 | Sep 4, 2025 | A | 228 | $71.38 | $16,275 | 7,909 | Yes | Form 4 |
| Maduck SeanSee Remarks | Sep 2, 2025 | Sep 4, 2025 | A | 228 | $0.00 | $0 | 8,137 | Yes | Form 4 |
| Maduck SeanSee Remarks | Sep 2, 2025 | Sep 4, 2025 | M · derivative | 20,000 | $5.05 | $101,000 | 1,986 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Sep 2, 2025 | Sep 4, 2025 | M | 5,000 | $13.56 | $67,800 | 15,066 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Sep 2, 2025 | Sep 4, 2025 | S | 4,895 | $70.24 | Sale −$343,825 | 10,171 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Sep 2, 2025 | Sep 4, 2025 | S | 105 | $70.76 | Sale −$7,430 | 10,066 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Sep 2, 2025 | Sep 4, 2025 | A | 200 | $71.38 | $14,276 | 10,266 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Sep 2, 2025 | Sep 4, 2025 | A | 200 | $0.00 | $0 | 10,466 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Sep 2, 2025 | Sep 4, 2025 | M · derivative | 5,000 | $13.56 | $67,800 | 26,571 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Sep 2, 2025 | Sep 4, 2025 | M | 20,000 | $21.65 | $433,000 | 25,487 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Sep 2, 2025 | Sep 4, 2025 | S | 15,594 | $70.39 | Sale −$1,097,662 | 9,893 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Sep 2, 2025 | Sep 4, 2025 | S | 4,406 | $70.85 | Sale −$312,165 | 5,487 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Sep 2, 2025 | Sep 4, 2025 | M · derivative | 20,000 | $21.65 | $433,000 | 330,000 | Yes | Form 4 |
| Robb Gary CharlesChief Business Officer | Aug 22, 2025 | Aug 26, 2025 | M | 5,000 | $3.88 | $19,400 | 18,364 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Aug 22, 2025 | Aug 26, 2025 | S | 2,326 | $71.27 | Sale −$165,774 | 16,038 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Aug 22, 2025 | Aug 26, 2025 | F | 2,674 | $71.17 | $190,309 | 13,364 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Aug 22, 2025 | Aug 26, 2025 | M · derivative | 5,000 | $3.88 | $19,400 | 145,000 | No | Form 4 |
| Swisher Daniel N JR | Aug 11, 2025 | Aug 12, 2025 | M | 2,200 | $14.08 | $30,976 | 2,200 | Yes | Form 4 |
| Swisher Daniel N JR | Aug 11, 2025 | Aug 12, 2025 | S | 2,200 | $72.30 | Sale −$159,060 | not reported | Yes | Form 4 |
| Swisher Daniel N JR | Aug 11, 2025 | Aug 12, 2025 | M · derivative | 2,200 | $14.08 | $30,976 | 5,500 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Aug 8, 2025 | Aug 12, 2025 | M | 35,007 | $21.65 | $757,902 | 40,494 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Aug 8, 2025 | Aug 12, 2025 | S | 35,007 | $71.77 | Sale −$2,512,452 | 5,487 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Aug 8, 2025 | Aug 12, 2025 | M · derivative | 35,007 | $21.65 | $757,902 | 350,000 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Aug 5, 2025 | Aug 7, 2025 | M | 14 | $21.65 | $303 | 5,501 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Aug 5, 2025 | Aug 7, 2025 | S | 14 | $71.77 | Sale −$1,005 | 5,487 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Aug 5, 2025 | Aug 7, 2025 | M · derivative | 14 | $21.65 | $303 | 385,007 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Aug 1, 2025 | Aug 5, 2025 | M | 5,823 | $13.56 | $78,960 | 15,889 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Aug 1, 2025 | Aug 5, 2025 | S | 5,823 | $67.51 | Sale −$393,111 | 10,066 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Aug 1, 2025 | Aug 5, 2025 | M · derivative | 5,823 | $13.56 | $78,960 | 31,571 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | Aug 1, 2025 | Aug 5, 2025 | S | 16,745 | $67.81 | Sale −$1,135,478 | 2,884,625 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | Aug 1, 2025 | Aug 5, 2025 | S | 17,809 | $68.87 | Sale −$1,226,506 | 2,866,816 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | Aug 1, 2025 | Aug 5, 2025 | S | 5,446 | $69.65 | Sale −$379,314 | 2,861,370 | Yes | Form 4 |
| Maduck SeanSee Remarks | Aug 1, 2025 | Aug 5, 2025 | M | 35,007 | $5.05 | $176,785 | 42,688 | Yes | Form 4 |
| Maduck SeanSee Remarks | Aug 1, 2025 | Aug 5, 2025 | S | 27,865 | $67.53 | Sale −$1,881,723 | 14,823 | Yes | Form 4 |
| Maduck SeanSee Remarks | Aug 1, 2025 | Aug 5, 2025 | S | 5,428 | $68.52 | Sale −$371,927 | 9,395 | Yes | Form 4 |
| Maduck SeanSee Remarks | Aug 1, 2025 | Aug 5, 2025 | S | 1,714 | $69.70 | Sale −$119,466 | 7,681 | Yes | Form 4 |
| Maduck SeanSee Remarks | Aug 1, 2025 | Aug 5, 2025 | M · derivative | 35,007 | $5.05 | $176,785 | 21,986 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jul 3, 2025 | Aug 5, 2025 | G | 40,000 | $0.00 | $0 | 59,717 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jul 3, 2025 | Aug 5, 2025 | J | 40,000 | $0.00 | $0 | 40,000 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jun 12, 2025 | Aug 5, 2025 | G | 10,024 | $0.00 | $0 | 7,681 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jun 12, 2025 | Aug 5, 2025 | J | 10,024 | $0.00 | $0 | 99,717 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jul 18, 2025 | Jul 21, 2025 | M | 500 | $21.65 | $10,825 | 5,987 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jul 18, 2025 | Jul 21, 2025 | S | 500 | $73.44 | Sale −$36,720 | 5,487 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jul 18, 2025 | Jul 21, 2025 | M · derivative | 500 | $21.65 | $10,825 | 385,021 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Jul 18, 2025 | Jul 21, 2025 | M | 200 | $13.56 | $2,712 | 10,266 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Jul 18, 2025 | Jul 21, 2025 | S | 200 | $73.40 | Sale −$14,680 | 10,066 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Jul 18, 2025 | Jul 21, 2025 | M · derivative | 200 | $13.56 | $2,712 | 37,394 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jul 18, 2025 | Jul 21, 2025 | M | 473 | $5.05 | $2,389 | 18,178 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jul 18, 2025 | Jul 21, 2025 | S | 473 | $73.44 | Sale −$34,737 | 17,705 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jul 18, 2025 | Jul 21, 2025 | M · derivative | 473 | $5.05 | $2,389 | 56,993 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jul 17, 2025 | Jul 21, 2025 | M | 4,379 | $21.65 | $94,805 | 9,866 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jul 17, 2025 | Jul 21, 2025 | S | 4,379 | $73.48 | Sale −$321,769 | 5,487 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jul 17, 2025 | Jul 21, 2025 | M · derivative | 4,379 | $21.65 | $94,805 | 385,521 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Jul 17, 2025 | Jul 21, 2025 | M | 3,877 | $13.56 | $52,572 | 13,943 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Jul 17, 2025 | Jul 21, 2025 | S | 3,877 | $73.48 | Sale −$284,882 | 10,066 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Jul 17, 2025 | Jul 21, 2025 | M · derivative | 3,877 | $13.56 | $52,572 | 37,594 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | Jul 17, 2025 | Jul 21, 2025 | S | 615 | $73.69 | Sale −$45,319 | 2,901,370 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jul 17, 2025 | Jul 21, 2025 | M | 4,315 | $5.05 | $21,791 | 22,020 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jul 17, 2025 | Jul 21, 2025 | S | 4,315 | $73.48 | Sale −$317,066 | 17,705 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jul 17, 2025 | Jul 21, 2025 | M · derivative | 4,315 | $5.05 | $21,791 | 57,466 | Yes | Form 4 |
| Swisher Daniel N JR | Jul 10, 2025 | Jul 14, 2025 | M | 2,200 | $14.08 | $30,976 | 2,200 | Yes | Form 4 |
| Swisher Daniel N JR | Jul 10, 2025 | Jul 14, 2025 | S | 2,200 | $71.08 | Sale −$156,376 | not reported | Yes | Form 4 |
| Swisher Daniel N JR | Jul 10, 2025 | Jul 14, 2025 | M · derivative | 2,200 | $14.08 | $30,976 | 7,700 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jul 1, 2025 | Jul 3, 2025 | M | 205 | $5.05 | $1,035 | 17,910 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jul 1, 2025 | Jul 3, 2025 | S | 205 | $73.45 | Sale −$15,057 | 17,705 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jul 1, 2025 | Jul 3, 2025 | M · derivative | 205 | $5.05 | $1,035 | 61,781 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Jul 1, 2025 | Jul 3, 2025 | M | 100 | $13.56 | $1,356 | 10,166 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Jul 1, 2025 | Jul 3, 2025 | S | 100 | $73.51 | Sale −$7,351 | 10,066 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Jul 1, 2025 | Jul 3, 2025 | M · derivative | 100 | $13.56 | $1,356 | 41,471 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jul 1, 2025 | Jul 3, 2025 | M | 100 | $21.65 | $2,165 | 5,587 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jul 1, 2025 | Jul 3, 2025 | S | 100 | $73.51 | Sale −$7,351 | 5,487 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jul 1, 2025 | Jul 3, 2025 | M · derivative | 100 | $21.65 | $2,165 | 389,900 | Yes | Form 4 |
| Robb Gary CharlesChief Business Officer | Jun 16, 2025 | Jun 18, 2025 | S | 3,185 | $70.77 | Sale −$225,402 | 13,364 | No | Form 4 |
| Mahoney David L | Jun 10, 2025 | Jun 12, 2025 | A · derivative | 15,000 | $72.27 | $1,084,050 | 15,000 | No | Form 4 |
| Alton Gregg H | Jun 10, 2025 | Jun 12, 2025 | A · derivative | 15,000 | $72.27 | $1,084,050 | 15,000 | No | Form 4 |
| Guyer WilliamChief Development Officer | Jun 10, 2025 | Jun 12, 2025 | M | 20,000 | $21.65 | $433,000 | 25,487 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jun 10, 2025 | Jun 12, 2025 | S | 16,918 | $72.36 | Sale −$1,224,186 | 8,569 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jun 10, 2025 | Jun 12, 2025 | S | 3,082 | $72.75 | Sale −$224,216 | 5,487 | Yes | Form 4 |
| Guyer WilliamChief Development Officer | Jun 10, 2025 | Jun 12, 2025 | M · derivative | 20,000 | $21.65 | $433,000 | 390,000 | Yes | Form 4 |
| Swisher Daniel N JR | Jun 10, 2025 | Jun 12, 2025 | M | 2,200 | $14.08 | $30,976 | 2,200 | Yes | Form 4 |
| Swisher Daniel N JR | Jun 10, 2025 | Jun 12, 2025 | S | 2,200 | $70.61 | Sale −$155,342 | not reported | Yes | Form 4 |
| Swisher Daniel N JR | Jun 10, 2025 | Jun 12, 2025 | M · derivative | 2,200 | $14.08 | $30,976 | 9,900 | Yes | Form 4 |
| Swisher Daniel N JR | Jun 10, 2025 | Jun 12, 2025 | A · derivative | 15,000 | $72.27 | $1,084,050 | 15,000 | Yes | Form 4 |
| Park Kimberly | Jun 10, 2025 | Jun 12, 2025 | A · derivative | 15,000 | $72.27 | $1,084,050 | 15,000 | No | Form 4 |
| Wilson James N | Jun 10, 2025 | Jun 12, 2025 | A · derivative | 25,000 | $72.27 | $1,806,750 | 25,000 | No | Form 4 |
| Murray Joshua M. | Jun 10, 2025 | Jun 12, 2025 | A · derivative | 15,000 | $72.27 | $1,084,050 | 15,000 | No | Form 4 |
| Cannon Gillian | Jun 10, 2025 | Jun 12, 2025 | A · derivative | 15,000 | $72.27 | $1,084,050 | 15,000 | No | Form 4 |
| Baker G Leonard Jr | Jun 10, 2025 | Jun 12, 2025 | A · derivative | 15,000 | $72.27 | $1,084,050 | 15,000 | No | Form 4 |
| Mokari AtabakChief Financial Officer | Jun 3, 2025 | Jun 4, 2025 | F | 519 | $71.68 | $37,202 | 14,065 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Jun 3, 2025 | Jun 4, 2025 | F | 651 | $71.68 | $46,664 | 16,549 | No | Form 4 |
| Lyon Joseph DouglasSee Remarks | Jun 3, 2025 | Jun 4, 2025 | F | 441 | $71.68 | $31,611 | 10,066 | Yes | Form 4 |
| Mokari AtabakChief Financial Officer | Jun 2, 2025 | Jun 4, 2025 | A | 775 | $71.68 | $55,552 | 13,809 | No | Form 4 |
| Mokari AtabakChief Financial Officer | Jun 2, 2025 | Jun 4, 2025 | A | 775 | $0.00 | $0 | 14,584 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Jun 2, 2025 | Jun 4, 2025 | A | 997 | $71.68 | $71,465 | 16,203 | No | Form 4 |
| Robb Gary CharlesChief Business Officer | Jun 2, 2025 | Jun 4, 2025 | A | 997 | $0.00 | $0 | 17,200 | No | Form 4 |
| Maduck SeanSee Remarks | Jun 2, 2025 | Jun 4, 2025 | A | 888 | $71.68 | $63,652 | 16,817 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jun 2, 2025 | Jun 4, 2025 | A | 888 | $0.00 | $0 | 17,705 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jun 2, 2025 | Jun 4, 2025 | A | 20,000 | $5.05 | $101,000 | 37,705 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jun 2, 2025 | Jun 4, 2025 | S | 5,752 | $77.91 | Sale −$448,138 | 31,953 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jun 2, 2025 | Jun 4, 2025 | S | 6,191 | $78.87 | Sale −$488,284 | 25,762 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jun 2, 2025 | Jun 4, 2025 | S | 6,246 | $79.89 | Sale −$498,993 | 19,516 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jun 2, 2025 | Jun 4, 2025 | S | 1,811 | $80.77 | Sale −$146,274 | 17,705 | Yes | Form 4 |
| Maduck SeanSee Remarks | Jun 2, 2025 | Jun 4, 2025 | M · derivative | 20,000 | $5.05 | $101,000 | 61,986 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Jun 2, 2025 | Jun 4, 2025 | M | 5,000 | $13.56 | $67,800 | 14,009 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Jun 2, 2025 | Jun 4, 2025 | S | 4,438 | $77.97 | Sale −$346,031 | 9,751 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Jun 2, 2025 | Jun 4, 2025 | S | 562 | $78.65 | Sale −$44,201 | 9,009 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Jun 2, 2025 | Jun 4, 2025 | A | 749 | $71.68 | $53,688 | 9,758 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Jun 2, 2025 | Jun 4, 2025 | A | 749 | $0.00 | $0 | 10,507 | Yes | Form 4 |
| Lyon Joseph DouglasSee Remarks | Jun 2, 2025 | Jun 4, 2025 | M · derivative | 5,000 | $13.56 | $67,800 | 41,571 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | Jun 2, 2025 | Jun 4, 2025 | S | 4,881 | $78.42 | Sale −$382,768 | 2,937,104 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | Jun 2, 2025 | Jun 4, 2025 | S | 3,050 | $79.48 | Sale −$242,414 | 2,934,054 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | Jun 2, 2025 | Jun 4, 2025 | S | 2,988 | $80.30 | Sale −$239,936 | 2,931,066 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | Jun 2, 2025 | Jun 4, 2025 | S | 1,820 | $81.33 | Sale −$148,021 | 2,929,246 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | Jun 2, 2025 | Jun 4, 2025 | S | 1,263 | $82.26 | Sale −$103,894 | 2,927,983 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | Jun 2, 2025 | Jun 4, 2025 | S | 4,631 | $83.46 | Sale −$386,503 | 2,923,352 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | Jun 2, 2025 | Jun 4, 2025 | S | 12,959 | $84.57 | Sale −$1,095,943 | 2,910,393 | Yes | Form 4 |
| Belanoff Joseph KChief Executive Officer | Jun 2, 2025 | Jun 4, 2025 | S | 8,408 | $85.01 | Sale −$714,764 | 2,901,985 | Yes | Form 4 |
| Maduck SeanSee Remarks | May 29, 2025 | Jun 2, 2025 | M | 10,000 | $3.88 | $38,800 | 25,929 | No | Form 4 |
| Maduck SeanSee Remarks | May 29, 2025 | Jun 2, 2025 | G | 10,000 | $0.00 | $0 | 15,929 | No | Form 4 |
| Maduck SeanSee Remarks | May 29, 2025 | Jun 2, 2025 | J | 10,000 | $0.00 | $0 | 89,693 | No | Form 4 |
| Maduck SeanSee Remarks | May 29, 2025 | Jun 2, 2025 | M · derivative | 10,000 | $3.88 | $38,800 | not reported | No | Form 4 |
| Maduck SeanSee Remarks | Mar 19, 2024 | Jun 2, 2025 | G | 10,000 | $0.00 | $0 | 15,929 | No | Form 4 |
| Maduck SeanSee Remarks | Mar 19, 2024 | Jun 2, 2025 | J | 10,000 | $0.00 | $0 | 79,693 | No | Form 4 |
| Maduck SeanSee Remarks | Sep 1, 2023 | Jun 2, 2025 | G | 1,059 | $0.00 | $0 | 25,929 | No | Form 4 |
| Maduck SeanSee Remarks | Sep 1, 2023 | Jun 2, 2025 | J | 1,059 | $0.00 | $0 | 69,693 | No | Form 4 |
| Maduck SeanSee Remarks | Jul 17, 2023 | Jun 2, 2025 | G | 10,000 | $0.00 | $0 | 26,988 | No | Form 4 |