CRSPCRISPR Therapeutics AG
- Market cap
- $4.78B
- as of 2026-10-23
- Latest close
- $49.39
- as of 2026-10-23
- Sector
- Healthcare
- as of 2026-10-24
- Industry
- Biotechnology
- as of 2026-10-24
Cluster
No cluster in the last 90 days under the default rule (14d · ≥2 insiders · all roles).
Form 4 historysince 2023-10-17
| Insider | Traded | Filed | Type | Shares | Price | Value | Owned after | 10b5-1 plan | Filing |
|---|---|---|---|---|---|---|---|---|---|
| Silver Andrew JacobChief Financial Officer | Oct 19 | Oct 21 | A · derivative | 25,000 | $0.00 | $0 | 25,000 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Oct 19 | Oct 20 | S | 47,837 | $49.78 | Sale −$2,381,326 | 311,899 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Oct 16 | Oct 20 | M | 100,000 | not reported | not reported | 359,736 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Oct 16 | Oct 20 | M · derivative | 100,000 | not reported | not reported | 200,000 | No | Form 4 |
| George Simeon | Oct 14 | Oct 16 | M | 30,000 | $14.00 | $420,000 | 30,000 | Yes | Form 4 |
| George Simeon | Oct 14 | Oct 16 | S | 14,514 | $49.63 | Sale −$720,373 | 15,486 | Yes | Form 4 |
| George Simeon | Oct 14 | Oct 16 | M · derivative | 30,000 | $14.00 | $420,000 | not reported | Yes | Form 4 |
| Kasinger James R.General Counsel and Secretary | Oct 14 | Oct 15 | S | 1,040 | $49.26 | Sale −$51,230 | 95,857 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Oct 14 | Oct 15 | S | 4,098 | $49.26 | Sale −$201,867 | 259,736 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Oct 13 | Oct 15 | M | 2,113 | not reported | not reported | 96,897 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Oct 13 | Oct 15 | M · derivative | 2,113 | not reported | not reported | not reported | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Oct 13 | Oct 15 | M | 8,333 | not reported | not reported | 263,834 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Oct 13 | Oct 15 | M · derivative | 8,333 | not reported | not reported | not reported | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Oct 6 | Oct 8 | M | 1,990 | $13.62 | $27,104 | 96,774 | Yes | Form 4 |
| Kasinger James R.General Counsel and Secretary | Oct 6 | Oct 8 | S | 1,990 | $60.04 | Sale −$119,481 | 94,784 | Yes | Form 4 |
| Kasinger James R.General Counsel and Secretary | Oct 6 | Oct 8 | M · derivative | 1,990 | $13.62 | $27,104 | 81,242 | Yes | Form 4 |
| Kasinger James R.General Counsel and Secretary | Sep 22 | Sep 24 | M | 10,400 | $13.62 | $141,648 | 105,184 | Yes | Form 4 |
| Kasinger James R.General Counsel and Secretary | Sep 22 | Sep 24 | S | 10,400 | $60.24 | Sale −$626,496 | 94,784 | Yes | Form 4 |
| Kasinger James R.General Counsel and Secretary | Sep 22 | Sep 24 | M · derivative | 10,400 | $13.62 | $141,648 | 83,232 | Yes | Form 4 |
| Behbahani Ali | Sep 17 | Sep 21 | M | 30,000 | $14.00 | $420,000 | 30,316 | No | Form 4 |
| Behbahani Ali | Sep 17 | Sep 21 | S | 13,679 | $57.09 | Sale −$780,934 | 16,637 | No | Form 4 |
| Behbahani Ali | Sep 17 | Sep 21 | M · derivative | 30,000 | $14.00 | $420,000 | not reported | No | Form 4 |
| Behbahani Ali | Aug 6, 2025 | Sep 21 | J | 60 | $0.00 | $0 | 316 | No | Form 4 |
| Behbahani Ali | Aug 6, 2025 | Sep 21 | J | 15 | $0.00 | $0 | 29 | No | Form 4 |
| Prasad RajuChief Financial Officer | Aug 7 | Aug 11 | G | 750 | $0.00 | $0 | 14,815 | No | Form 4 |
| Treco Douglas A | Jun 5 | Jun 9 | A · derivative | 13,000 | $51.84 | $673,920 | 13,000 | No | Form 4 |
| Rommel Christian | Jun 5 | Jun 9 | A · derivative | 13,000 | $51.84 | $673,920 | 13,000 | No | Form 4 |
| Morrison Briggs | Jun 5 | Jun 9 | A · derivative | 13,000 | $51.84 | $673,920 | 13,000 | No | Form 4 |
| Mahatme Sandesh | Jun 5 | Jun 9 | A · derivative | 13,000 | $51.84 | $673,920 | 13,000 | No | Form 4 |
| High Katherine A | Jun 5 | Jun 9 | A · derivative | 13,000 | $51.84 | $673,920 | 13,000 | No | Form 4 |
| Greene John | Jun 5 | Jun 9 | A · derivative | 13,000 | $51.84 | $673,920 | 13,000 | No | Form 4 |
| Fleming Harold Edward | Jun 5 | Jun 9 | A · derivative | 13,000 | $51.84 | $673,920 | 13,000 | No | Form 4 |
| Fardis Maria | Jun 5 | Jun 9 | A · derivative | 13,000 | $51.84 | $673,920 | 13,000 | No | Form 4 |
| Behbahani Ali | Jun 5 | Jun 9 | A · derivative | 13,000 | $51.84 | $673,920 | 13,000 | No | Form 4 |
| George Simeon | Jun 5 | Jun 9 | A · derivative | 13,000 | $51.84 | $673,920 | 13,000 | No | Form 4 |
| Prasad RajuChief Financial Officer | May 29 | Jun 2 | A · derivative | 19,500 | $0.00 | $0 | 19,500 | No | Form 4 |
| Patel NaimishChief Medical Officer | May 29 | Jun 2 | A · derivative | 22,000 | $0.00 | $0 | 22,000 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | May 29 | Jun 2 | A · derivative | 17,000 | $0.00 | $0 | 17,000 | No | Form 4 |
| Patel NaimishChief Medical Officer | May 29 | Jun 1 | S | 3,786 | $55.62 | Sale −$210,577 | 19,357 | No | Form 4 |
| Patel NaimishChief Medical Officer | May 28 | Jun 1 | M | 10,000 | not reported | not reported | 23,143 | No | Form 4 |
| Patel NaimishChief Medical Officer | May 28 | Jun 1 | M · derivative | 10,000 | not reported | not reported | 20,000 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 23 | Mar 24 | S | 3,708 | $46.78 | Sale −$173,460 | 15,565 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 23 | Mar 24 | S | 10,020 | $46.78 | Sale −$468,736 | 255,501 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 23 | Mar 24 | S | 3,182 | $46.78 | Sale −$148,854 | 94,308 | No | Form 4 |
| Patel NaimishChief Medical Officer | Mar 20 | Mar 24 | A · derivative | 38,499 | $46.24 | $1,780,194 | 38,499 | No | Form 4 |
| Patel NaimishChief Medical Officer | Mar 20 | Mar 24 | A · derivative | 30,000 | $0.00 | $0 | 30,000 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 20 | Mar 24 | M | 6,250 | not reported | not reported | 19,273 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 20 | Mar 24 | A · derivative | 38,499 | $46.24 | $1,780,194 | 38,499 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 20 | Mar 24 | A · derivative | 27,500 | $0.00 | $0 | 27,500 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 20 | Mar 24 | M · derivative | 6,250 | not reported | not reported | 12,500 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 20 | Mar 24 | M | 19,687 | not reported | not reported | 265,521 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 20 | Mar 24 | A · derivative | 114,249 | $46.24 | $5,282,874 | 114,249 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 20 | Mar 24 | A · derivative | 81,875 | $0.00 | $0 | 81,875 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 20 | Mar 24 | M · derivative | 19,687 | not reported | not reported | 39,375 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 20 | Mar 24 | M | 6,250 | not reported | not reported | 97,490 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 20 | Mar 24 | A · derivative | 38,499 | $46.24 | $1,780,194 | 38,499 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 20 | Mar 24 | A · derivative | 25,000 | $0.00 | $0 | 25,000 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 20 | Mar 24 | M · derivative | 6,250 | not reported | not reported | 12,000 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 16 | Mar 17 | S | 10,349 | $48.26 | Sale −$499,443 | 245,834 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 16 | Mar 17 | S | 3,450 | $48.26 | Sale −$166,497 | 91,240 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 16 | Mar 17 | S | 5,848 | $48.26 | Sale −$282,224 | 17,794 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 16 | Mar 17 | S | 4,021 | $48.26 | Sale −$194,053 | 13,773 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 16 | Mar 17 | G | 750 | $0.00 | $0 | 13,023 | No | Form 4 |
| Patel NaimishChief Medical Officer | Mar 16 | Mar 17 | S | 3,150 | $48.26 | Sale −$152,019 | 13,143 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 14 | Mar 17 | M | 20,625 | not reported | not reported | 256,183 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 14 | Mar 17 | M · derivative | 20,625 | not reported | not reported | 61,875 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 14 | Mar 17 | M | 6,875 | not reported | not reported | 94,690 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 14 | Mar 17 | M · derivative | 6,875 | not reported | not reported | 20,625 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 14 | Mar 17 | M | 10,000 | not reported | not reported | 16,767 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 14 | Mar 17 | M | 6,875 | not reported | not reported | 23,642 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 14 | Mar 17 | M · derivative | 10,000 | not reported | not reported | 10,000 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 14 | Mar 17 | M · derivative | 6,875 | not reported | not reported | 20,625 | No | Form 4 |
| Patel NaimishChief Medical Officer | Mar 14 | Mar 17 | M | 8,125 | not reported | not reported | 16,293 | No | Form 4 |
| Patel NaimishChief Medical Officer | Mar 14 | Mar 17 | M · derivative | 8,125 | not reported | not reported | 24,375 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 11 | Mar 12 | S | 9,798 | $52.80 | Sale −$517,334 | 235,558 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 11 | Mar 12 | S | 2,800 | $52.80 | Sale −$147,840 | 87,815 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 10 | Mar 12 | M | 19,250 | not reported | not reported | 245,356 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 10 | Mar 12 | M · derivative | 19,250 | not reported | not reported | 19,250 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 10 | Mar 12 | M | 5,500 | not reported | not reported | 90,615 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 10 | Mar 12 | M · derivative | 5,500 | not reported | not reported | 5,500 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Feb 19 | Feb 20 | S | 2,112 | $52.58 | Sale −$111,049 | 85,115 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Feb 19 | Feb 20 | S | 6,967 | $52.58 | Sale −$366,325 | 226,106 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Feb 18 | Feb 20 | M | 3,825 | not reported | not reported | 87,227 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Feb 18 | Feb 20 | M · derivative | 3,825 | not reported | not reported | not reported | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Feb 18 | Feb 20 | M | 13,250 | not reported | not reported | 233,073 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Feb 18 | Feb 20 | M · derivative | 13,250 | not reported | not reported | not reported | No | Form 4 |
| Patel NaimishChief Medical Officer | Apr 3, 2025 | Jan 27 | P | 1,508 | $32.96 | Purchase +$49,704 | 1,508 | No | Form 4 |
| Prasad RajuChief Financial Officer | Jan 22 | Jan 26 | M | 34,972 | $45.15 | $1,578,986 | 41,739 | Yes | Form 4 |
| Prasad RajuChief Financial Officer | Jan 22 | Jan 26 | S | 34,972 | $60.19 | Sale −$2,104,965 | 6,767 | Yes | Form 4 |
| Prasad RajuChief Financial Officer | Jan 22 | Jan 26 | M · derivative | 34,972 | $45.15 | $1,578,986 | 41,667 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Jan 22 | Jan 22 | S | 60,000 | $60.23 | Sale −$3,613,800 | 134,201 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Jan 20 | Jan 22 | S | 21,433 | $51.61 | Sale −$1,106,157 | 202,768 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Jan 20 | Jan 22 | S | 8,567 | $52.10 | Sale −$446,341 | 194,201 | Yes | Form 4 |
| Prasad RajuChief Financial Officer | Jan 6 | Jan 8 | M | 23,361 | $45.15 | $1,054,749 | 30,128 | Yes | Form 4 |
| Prasad RajuChief Financial Officer | Jan 6 | Jan 8 | M | 6,339 | $44.31 | $280,881 | 36,467 | Yes | Form 4 |
| Prasad RajuChief Financial Officer | Jan 6 | Jan 8 | S | 18,933 | $60.18 | Sale −$1,139,388 | 17,534 | Yes | Form 4 |
| Prasad RajuChief Financial Officer | Jan 6 | Jan 8 | S | 5,004 | $60.00 | Sale −$300,240 | 12,530 | Yes | Form 4 |
| Prasad RajuChief Financial Officer | Jan 6 | Jan 8 | S | 5,763 | $60.21 | Sale −$346,990 | 6,767 | Yes | Form 4 |
| Prasad RajuChief Financial Officer | Jan 6 | Jan 8 | M · derivative | 23,361 | $45.15 | $1,054,749 | 76,639 | Yes | Form 4 |
| Prasad RajuChief Financial Officer | Jan 6 | Jan 8 | M · derivative | 6,339 | $44.31 | $280,881 | 7,493 | Yes | Form 4 |
| Prasad RajuChief Financial Officer | Dec 22, 2025 | Dec 23, 2025 | S | 3,528 | $55.10 | Sale −$194,393 | 13,239 | Yes | Form 4 |
| Prasad RajuChief Financial Officer | Dec 22, 2025 | Dec 23, 2025 | S | 5,472 | $56.33 | Sale −$308,238 | 7,767 | Yes | Form 4 |
| Prasad RajuChief Financial Officer | Dec 22, 2025 | Dec 23, 2025 | S | 1,000 | $56.89 | Sale −$56,890 | 6,767 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Dec 18, 2025 | Dec 22, 2025 | G | 30,000 | $0.00 | $0 | 224,201 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Oct 17, 2025 | Oct 20, 2025 | S | 50,895 | $67.91 | Sale −$3,456,279 | 254,201 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Oct 16, 2025 | Oct 20, 2025 | M | 100,000 | not reported | not reported | 305,096 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Oct 16, 2025 | Oct 20, 2025 | M · derivative | 100,000 | not reported | not reported | 300,000 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Oct 14, 2025 | Oct 15, 2025 | S | 1,076 | $66.60 | Sale −$71,662 | 83,402 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Oct 14, 2025 | Oct 15, 2025 | S | 4,242 | $66.60 | Sale −$282,517 | 205,096 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Oct 13, 2025 | Oct 15, 2025 | M | 2,114 | not reported | not reported | 84,478 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Oct 13, 2025 | Oct 15, 2025 | M · derivative | 2,114 | not reported | not reported | 2,113 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Oct 13, 2025 | Oct 15, 2025 | M | 8,334 | not reported | not reported | 209,338 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Oct 13, 2025 | Oct 15, 2025 | M · derivative | 8,334 | not reported | not reported | 8,333 | No | Form 4 |
| Prasad RajuChief Financial Officer | Oct 3, 2025 | Oct 3, 2025 | A · derivative | 16,500 | $67.74 | $1,117,710 | 16,500 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Oct 3, 2025 | Oct 3, 2025 | A · derivative | 16,500 | $67.74 | $1,117,710 | 16,500 | No | Form 4 |
| Patel NaimishChief Medical Officer | Oct 3, 2025 | Oct 3, 2025 | A · derivative | 16,500 | $67.74 | $1,117,710 | 16,500 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Oct 3, 2025 | Oct 3, 2025 | A · derivative | 49,500 | $67.74 | $3,353,130 | 49,500 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Sep 17, 2025 | Sep 19, 2025 | G | 6,000 | $0.00 | $0 | 201,004 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Aug 18, 2025 | Aug 19, 2025 | S | 13,081 | $58.15 | Sale −$760,660 | 207,004 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Aug 16, 2025 | Aug 19, 2025 | M | 25,000 | not reported | not reported | 220,085 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Aug 16, 2025 | Aug 19, 2025 | M · derivative | 25,000 | not reported | not reported | not reported | No | Form 4 |
| Treco Douglas A | Aug 6, 2025 | Aug 8, 2025 | P | 20,000 | $57.03 | Purchase +$1,140,600 | 22,000 | No | Form 4 |
| George Simeon | Jul 16, 2025 | Jul 17, 2025 | P | 6,510 | $52.03 | Purchase +$338,715 | 69,687 | No | Form 4 |
| George Simeon | Jul 16, 2025 | Jul 17, 2025 | P | 22,319 | $52.03 | Purchase +$1,161,258 | 238,897 | No | Form 4 |
| George Simeon | Jul 16, 2025 | Jul 17, 2025 | P | 960,983 | $52.03 | Purchase +$49,999,945 | 1,730,179 | No | Form 4 |
| High Katherine A | Jun 5, 2025 | Jun 6, 2025 | A · derivative | 13,000 | $38.57 | $501,410 | 13,000 | No | Form 4 |
| Fardis Maria | Jun 5, 2025 | Jun 6, 2025 | A · derivative | 13,000 | $38.57 | $501,410 | 13,000 | No | Form 4 |
| Mahatme Sandesh | Jun 5, 2025 | Jun 6, 2025 | A · derivative | 13,000 | $38.57 | $501,410 | 13,000 | No | Form 4 |
| Greene John | Jun 5, 2025 | Jun 6, 2025 | A · derivative | 13,000 | $38.57 | $501,410 | 13,000 | No | Form 4 |
| Fleming Harold Edward | Jun 5, 2025 | Jun 6, 2025 | A · derivative | 13,000 | $38.57 | $501,410 | 13,000 | No | Form 4 |
| Rommel Christian | Jun 5, 2025 | Jun 6, 2025 | A · derivative | 13,000 | $38.57 | $501,410 | 13,000 | No | Form 4 |
| Treco Douglas A | Jun 5, 2025 | Jun 6, 2025 | A · derivative | 13,000 | $38.57 | $501,410 | 13,000 | No | Form 4 |
| Morrison Briggs | Jun 5, 2025 | Jun 6, 2025 | A · derivative | 13,000 | $38.57 | $501,410 | 13,000 | No | Form 4 |
| Behbahani Ali | Jun 5, 2025 | Jun 6, 2025 | A · derivative | 13,000 | $38.57 | $501,410 | 13,000 | No | Form 4 |
| George Simeon | Jun 5, 2025 | Jun 6, 2025 | A · derivative | 13,000 | $38.57 | $501,410 | 13,000 | No | Form 4 |
| Patel NaimishChief Medical Officer | May 30, 2025 | Jun 3, 2025 | A · derivative | 25,000 | $0.00 | $0 | 25,000 | No | Form 4 |
| Prasad RajuChief Financial Officer | May 30, 2025 | Jun 3, 2025 | A · derivative | 20,000 | $0.00 | $0 | 20,000 | No | Form 4 |
| Patel NaimishChief Medical Officer | May 29, 2025 | May 30, 2025 | S | 3,932 | $35.94 | Sale −$141,316 | 6,068 | No | Form 4 |
| Patel NaimishChief Medical Officer | May 28, 2025 | May 30, 2025 | M | 10,000 | not reported | not reported | 10,000 | No | Form 4 |
| Patel NaimishChief Medical Officer | May 28, 2025 | May 30, 2025 | M · derivative | 10,000 | not reported | not reported | 30,000 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 21, 2025 | Mar 24, 2025 | S | 3,185 | $41.23 | Sale −$131,318 | 81,729 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 21, 2025 | Mar 24, 2025 | S | 2,197 | $41.23 | Sale −$90,582 | 16,767 | No | Form 4 |
| Bruno JulianneChief Operating Officer | Mar 21, 2025 | Mar 24, 2025 | S | 1,714 | $41.23 | Sale −$70,668 | 10,544 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 21, 2025 | Mar 24, 2025 | S | 10,031 | $41.23 | Sale −$413,578 | 195,085 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 20, 2025 | Mar 24, 2025 | M | 6,250 | not reported | not reported | 84,914 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 20, 2025 | Mar 24, 2025 | M · derivative | 6,250 | not reported | not reported | 18,750 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 20, 2025 | Mar 24, 2025 | M | 6,250 | not reported | not reported | 18,964 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 20, 2025 | Mar 24, 2025 | M · derivative | 6,250 | not reported | not reported | 18,750 | No | Form 4 |
| Bruno JulianneChief Operating Officer | Mar 20, 2025 | Mar 24, 2025 | M | 3,750 | not reported | not reported | 12,258 | No | Form 4 |
| Bruno JulianneChief Operating Officer | Mar 20, 2025 | Mar 24, 2025 | M · derivative | 3,750 | not reported | not reported | 11,250 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 20, 2025 | Mar 24, 2025 | M | 19,688 | not reported | not reported | 205,116 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 20, 2025 | Mar 24, 2025 | M · derivative | 19,688 | not reported | not reported | 59,062 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 17, 2025 | Mar 18, 2025 | S | 3,762 | $41.80 | Sale −$157,252 | 12,714 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 14, 2025 | Mar 18, 2025 | A · derivative | 36,666 | $42.12 | $1,544,372 | 36,666 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 14, 2025 | Mar 18, 2025 | A · derivative | 27,500 | $0.00 | $0 | 27,500 | No | Form 4 |
| Bruno JulianneChief Operating Officer | Mar 14, 2025 | Mar 18, 2025 | A · derivative | 36,666 | $42.12 | $1,544,372 | 36,666 | No | Form 4 |
| Bruno JulianneChief Operating Officer | Mar 14, 2025 | Mar 18, 2025 | A · derivative | 27,500 | $0.00 | $0 | 27,500 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 14, 2025 | Mar 18, 2025 | A · derivative | 110,000 | $42.12 | $4,633,200 | 110,000 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 14, 2025 | Mar 18, 2025 | A · derivative | 82,500 | $0.00 | $0 | 82,500 | No | Form 4 |
| Patel NaimishChief Medical Officer | Mar 14, 2025 | Mar 18, 2025 | A · derivative | 46,667 | $42.12 | $1,965,614 | 46,667 | No | Form 4 |
| Patel NaimishChief Medical Officer | Mar 14, 2025 | Mar 18, 2025 | A · derivative | 32,500 | $0.00 | $0 | 32,500 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 14, 2025 | Mar 18, 2025 | M | 10,000 | not reported | not reported | 16,476 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 14, 2025 | Mar 18, 2025 | M · derivative | 10,000 | not reported | not reported | 20,000 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 14, 2025 | Mar 18, 2025 | A · derivative | 36,666 | $42.12 | $1,544,372 | 36,666 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 14, 2025 | Mar 18, 2025 | A · derivative | 27,500 | $0.00 | $0 | 27,500 | No | Form 4 |
| Bruno JulianneChief Operating Officer | Mar 12, 2025 | Mar 12, 2025 | S | 190 | $43.32 | Sale −$8,231 | 8,508 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 12, 2025 | Mar 12, 2025 | S | 1,116 | $43.32 | Sale −$48,345 | 78,664 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 12, 2025 | Mar 12, 2025 | S | 4,462 | $43.32 | Sale −$193,294 | 185,428 | No | Form 4 |
| Bruno JulianneChief Operating Officer | Mar 11, 2025 | Mar 12, 2025 | S | 1,198 | $42.42 | Sale −$50,819 | 8,263 | No | Form 4 |
| Bruno JulianneChief Operating Officer | Mar 11, 2025 | Mar 12, 2025 | M | 435 | not reported | not reported | 8,698 | No | Form 4 |
| Bruno JulianneChief Operating Officer | Mar 11, 2025 | Mar 12, 2025 | M · derivative | 435 | not reported | not reported | not reported | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 11, 2025 | Mar 12, 2025 | S | 2,850 | $42.42 | Sale −$120,897 | 77,530 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 11, 2025 | Mar 12, 2025 | M | 2,250 | not reported | not reported | 79,780 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 11, 2025 | Mar 12, 2025 | M · derivative | 2,250 | not reported | not reported | not reported | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 11, 2025 | Mar 12, 2025 | S | 9,973 | $42.42 | Sale −$423,055 | 180,890 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 11, 2025 | Mar 12, 2025 | M | 9,000 | not reported | not reported | 189,890 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 11, 2025 | Mar 12, 2025 | M · derivative | 9,000 | not reported | not reported | not reported | No | Form 4 |
| Bruno JulianneChief Operating Officer | Mar 10, 2025 | Mar 12, 2025 | M | 2,399 | not reported | not reported | 9,461 | No | Form 4 |
| Bruno JulianneChief Operating Officer | Mar 10, 2025 | Mar 12, 2025 | M · derivative | 2,399 | not reported | not reported | 4,796 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 10, 2025 | Mar 12, 2025 | M | 5,500 | not reported | not reported | 80,380 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 10, 2025 | Mar 12, 2025 | M · derivative | 5,500 | not reported | not reported | 11,000 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 10, 2025 | Mar 12, 2025 | M | 19,250 | not reported | not reported | 190,863 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 10, 2025 | Mar 12, 2025 | M · derivative | 19,250 | not reported | not reported | 38,500 | No | Form 4 |
| Greene John | Feb 26, 2025 | Feb 28, 2025 | P | 7,000 | $44.85 | Purchase +$313,950 | 7,000 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Feb 19, 2025 | Feb 21, 2025 | S | 18,360 | $55.21 | Sale −$1,013,656 | 171,613 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Feb 19, 2025 | Feb 19, 2025 | S | 6,928 | $52.80 | Sale −$365,798 | 189,973 | Yes | Form 4 |
| Kasinger James R.General Counsel and Secretary | Feb 19, 2025 | Feb 19, 2025 | S | 1,947 | $52.80 | Sale −$102,802 | 74,880 | No | Form 4 |
| Bruno JulianneChief Operating Officer | Feb 19, 2025 | Feb 19, 2025 | S | 333 | $52.80 | Sale −$17,582 | 7,062 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Feb 18, 2025 | Feb 19, 2025 | M | 13,250 | not reported | not reported | 208,541 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Feb 18, 2025 | Feb 19, 2025 | S | 11,640 | $55.05 | Sale −$640,782 | 196,901 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Feb 18, 2025 | Feb 19, 2025 | M · derivative | 13,250 | not reported | not reported | 13,250 | Yes | Form 4 |
| Kasinger James R.General Counsel and Secretary | Feb 18, 2025 | Feb 19, 2025 | S | 9,595 | $53.85 | Sale −$516,691 | 73,002 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Feb 18, 2025 | Feb 19, 2025 | M | 3,825 | not reported | not reported | 76,827 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Feb 18, 2025 | Feb 19, 2025 | M · derivative | 3,825 | not reported | not reported | 3,825 | No | Form 4 |
| Bruno JulianneChief Operating Officer | Feb 18, 2025 | Feb 19, 2025 | M | 650 | not reported | not reported | 7,395 | No | Form 4 |
| Bruno JulianneChief Operating Officer | Feb 18, 2025 | Feb 19, 2025 | M · derivative | 650 | not reported | not reported | 650 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Feb 16, 2025 | Feb 19, 2025 | M | 20,000 | not reported | not reported | 82,597 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Feb 16, 2025 | Feb 19, 2025 | M · derivative | 20,000 | not reported | not reported | not reported | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Dec 24, 2024 | Dec 27, 2024 | M | 13,751 | $16.21 | $222,904 | 195,291 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Dec 24, 2024 | Dec 27, 2024 | M · derivative | 13,751 | $16.21 | $222,904 | not reported | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Dec 2, 2024 | Dec 4, 2024 | S | 15,000 | $55.10 | Sale −$826,500 | 181,540 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Nov 11, 2024 | Nov 13, 2024 | S | 23,121 | $55.43 | Sale −$1,281,597 | 203,419 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Nov 11, 2024 | Nov 13, 2024 | S | 6,879 | $56.27 | Sale −$387,081 | 196,540 | Yes | Form 4 |
| Prasad RajuChief Financial Officer | Oct 16, 2024 | Oct 18, 2024 | A · derivative | 18,333 | $49.00 | $898,317 | 18,333 | No | Form 4 |
| Prasad RajuChief Financial Officer | Oct 16, 2024 | Oct 18, 2024 | A · derivative | 15,000 | $0.00 | $0 | 15,000 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Oct 16, 2024 | Oct 18, 2024 | A · derivative | 55,000 | $49.00 | $2,695,000 | 55,000 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Oct 16, 2024 | Oct 18, 2024 | A · derivative | 400,000 | $0.00 | $0 | 400,000 | No | Form 4 |
| Bruno JulianneChief Operating Officer | Oct 16, 2024 | Oct 18, 2024 | A · derivative | 18,333 | $49.00 | $898,317 | 18,333 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Oct 16, 2024 | Oct 18, 2024 | A · derivative | 18,333 | $49.00 | $898,317 | 18,333 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Oct 16, 2024 | Oct 18, 2024 | A · derivative | 30,000 | $0.00 | $0 | 30,000 | No | Form 4 |
| Patel NaimishChief Medical Officer | Oct 16, 2024 | Oct 18, 2024 | A · derivative | 18,333 | $49.00 | $898,317 | 18,333 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Oct 14, 2024 | Oct 15, 2024 | S | 4,293 | $46.28 | Sale −$198,680 | 226,540 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Oct 14, 2024 | Oct 15, 2024 | S | 1,089 | $46.28 | Sale −$50,399 | 62,597 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Oct 13, 2024 | Oct 15, 2024 | M | 8,333 | not reported | not reported | 230,833 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Oct 13, 2024 | Oct 15, 2024 | M · derivative | 8,333 | not reported | not reported | 16,667 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Oct 13, 2024 | Oct 15, 2024 | M | 2,113 | not reported | not reported | 63,686 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Oct 13, 2024 | Oct 15, 2024 | M · derivative | 2,113 | not reported | not reported | 4,227 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Aug 8, 2024 | Aug 12, 2024 | G | 100,000 | $0.00 | $0 | 222,500 | No | Form 4 |
| Bruno JulianneChief Operating Officer | Jun 21, 2024 | Jun 24, 2024 | S | 3,366 | $56.09 | Sale −$188,799 | 6,745 | No | Form 4 |
| Bruno JulianneChief Operating Officer | Jun 20, 2024 | Jun 24, 2024 | M | 7,000 | not reported | not reported | 10,111 | No | Form 4 |
| Bruno JulianneChief Operating Officer | Jun 20, 2024 | Jun 24, 2024 | M · derivative | 7,000 | not reported | not reported | not reported | No | Form 4 |
| Fleming Harold Edward | May 30, 2024 | May 31, 2024 | A · derivative | 13,000 | $54.06 | $702,780 | 13,000 | No | Form 4 |
| Rommel Christian | May 30, 2024 | May 31, 2024 | A · derivative | 26,000 | $54.06 | $1,405,560 | 26,000 | No | Form 4 |
| Treco Douglas A | May 30, 2024 | May 31, 2024 | A · derivative | 13,000 | $54.06 | $702,780 | 13,000 | No | Form 4 |
| Greene John | May 30, 2024 | May 31, 2024 | A · derivative | 13,000 | $54.06 | $702,780 | 13,000 | No | Form 4 |
| Fardis Maria | May 30, 2024 | May 31, 2024 | A · derivative | 13,000 | $54.06 | $702,780 | 13,000 | No | Form 4 |
| High Katherine A | May 30, 2024 | May 31, 2024 | A · derivative | 13,000 | $54.06 | $702,780 | 13,000 | No | Form 4 |
| Mahatme Sandesh | May 30, 2024 | May 31, 2024 | A · derivative | 13,000 | $54.06 | $702,780 | 13,000 | No | Form 4 |
| Behbahani Ali | May 30, 2024 | May 31, 2024 | A · derivative | 13,000 | $54.06 | $702,780 | 13,000 | No | Form 4 |
| George Simeon | May 30, 2024 | May 31, 2024 | A · derivative | 13,000 | $54.06 | $702,780 | 13,000 | No | Form 4 |
| Patel NaimishChief Medical Officer | May 28, 2024 | May 29, 2024 | A · derivative | 85,000 | $54.84 | $4,661,400 | 85,000 | No | Form 4 |
| Patel NaimishChief Medical Officer | May 28, 2024 | May 29, 2024 | A · derivative | 40,000 | $0.00 | $0 | 40,000 | No | Form 4 |
| Bruno JulianneChief Operating Officer | May 23, 2024 | May 24, 2024 | A · derivative | 20,000 | $0.00 | $0 | 20,000 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Apr 15, 2024 | Apr 17, 2024 | M | 19,582 | $19.12 | $374,408 | 227,704 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Apr 15, 2024 | Apr 17, 2024 | S | 18,378 | $59.88 | Sale −$1,100,475 | 209,326 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Apr 15, 2024 | Apr 17, 2024 | S | 1,204 | $60.40 | Sale −$72,722 | 208,122 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Apr 15, 2024 | Apr 17, 2024 | M · derivative | 19,582 | $19.12 | $374,408 | not reported | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 20, 2024 | Mar 22, 2024 | A · derivative | 105,000 | $72.94 | $7,658,700 | 105,000 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 20, 2024 | Mar 22, 2024 | A · derivative | 78,750 | $0.00 | $0 | 78,750 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 20, 2024 | Mar 22, 2024 | A · derivative | 36,168 | $72.94 | $2,638,094 | 36,168 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 20, 2024 | Mar 22, 2024 | A · derivative | 25,000 | $0.00 | $0 | 25,000 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 20, 2024 | Mar 22, 2024 | A · derivative | 33,333 | $72.94 | $2,431,309 | 33,333 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 20, 2024 | Mar 22, 2024 | A · derivative | 25,000 | $0.00 | $0 | 25,000 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 15, 2024 | Mar 18, 2024 | M | 20,000 | $19.12 | $382,400 | 228,122 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 15, 2024 | Mar 18, 2024 | S | 10,613 | $71.97 | Sale −$763,818 | 217,509 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 15, 2024 | Mar 18, 2024 | S | 9,387 | $73.06 | Sale −$685,814 | 208,122 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 15, 2024 | Mar 18, 2024 | M · derivative | 20,000 | $19.12 | $382,400 | 19,582 | Yes | Form 4 |
| Prasad RajuChief Financial Officer | Mar 15, 2024 | Mar 18, 2024 | S | 3,524 | $72.69 | Sale −$256,160 | 6,476 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 14, 2024 | Mar 18, 2024 | M | 10,000 | not reported | not reported | 10,000 | No | Form 4 |
| Prasad RajuChief Financial Officer | Mar 14, 2024 | Mar 18, 2024 | M · derivative | 10,000 | not reported | not reported | 30,000 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 12, 2024 | Mar 12, 2024 | S | 4,583 | $74.44 | Sale −$341,159 | 208,122 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 12, 2024 | Mar 12, 2024 | S | 1,146 | $74.44 | Sale −$85,308 | 61,174 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 11, 2024 | Mar 12, 2024 | S | 9,802 | $78.26 | Sale −$767,105 | 203,705 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 11, 2024 | Mar 12, 2024 | M | 9,000 | not reported | not reported | 212,705 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 11, 2024 | Mar 12, 2024 | M · derivative | 9,000 | not reported | not reported | 9,000 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 11, 2024 | Mar 12, 2024 | S | 2,801 | $78.26 | Sale −$219,206 | 60,070 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 11, 2024 | Mar 12, 2024 | M | 2,250 | not reported | not reported | 62,320 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 11, 2024 | Mar 12, 2024 | M · derivative | 2,250 | not reported | not reported | 2,250 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 10, 2024 | Mar 12, 2024 | M | 19,250 | not reported | not reported | 213,507 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Mar 10, 2024 | Mar 12, 2024 | M · derivative | 19,250 | not reported | not reported | 57,750 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 10, 2024 | Mar 12, 2024 | M | 5,500 | not reported | not reported | 62,871 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Mar 10, 2024 | Mar 12, 2024 | M · derivative | 5,500 | not reported | not reported | 16,500 | No | Form 4 |
| George Simeon | Feb 27, 2024 | Feb 27, 2024 | A | 63,177 | $71.50 | $4,517,156 | 63,177 | No | Form 4 |
| George Simeon | Feb 27, 2024 | Feb 27, 2024 | A | 216,578 | $71.50 | $15,485,327 | 216,578 | No | Form 4 |
| George Simeon | Feb 27, 2024 | Feb 27, 2024 | A | 769,196 | $71.50 | $54,997,514 | 769,196 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Feb 20, 2024 | Feb 21, 2024 | S | 6,370 | $79.67 | Sale −$507,498 | 194,257 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Feb 20, 2024 | Feb 21, 2024 | S | 1,913 | $79.67 | Sale −$152,409 | 57,371 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Feb 18, 2024 | Feb 21, 2024 | M | 13,250 | not reported | not reported | 200,627 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Feb 18, 2024 | Feb 21, 2024 | M · derivative | 13,250 | not reported | not reported | 26,500 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Feb 18, 2024 | Feb 21, 2024 | M | 3,825 | not reported | not reported | 59,284 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Feb 18, 2024 | Feb 21, 2024 | M · derivative | 3,825 | not reported | not reported | 7,650 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Feb 15, 2024 | Feb 16, 2024 | M | 20,000 | $19.12 | $382,400 | 207,377 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Feb 15, 2024 | Feb 16, 2024 | S | 12,949 | $79.94 | Sale −$1,035,143 | 194,428 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Feb 15, 2024 | Feb 16, 2024 | S | 5,951 | $81.04 | Sale −$482,269 | 188,477 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Feb 15, 2024 | Feb 16, 2024 | S | 1,100 | $81.66 | Sale −$89,826 | 187,377 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Feb 15, 2024 | Feb 16, 2024 | M · derivative | 20,000 | $19.12 | $382,400 | 39,582 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Jan 29, 2024 | Jan 31, 2024 | M | 50,000 | $19.12 | $956,000 | 237,377 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Jan 29, 2024 | Jan 31, 2024 | S | 49,300 | $60.50 | Sale −$2,982,650 | 188,077 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Jan 29, 2024 | Jan 31, 2024 | S | 700 | $61.10 | Sale −$42,770 | 187,377 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Jan 29, 2024 | Jan 31, 2024 | M · derivative | 50,000 | $19.12 | $956,000 | 100,000 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Jan 16, 2024 | Jan 18, 2024 | M | 20,000 | $19.12 | $382,400 | 207,377 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Jan 16, 2024 | Jan 18, 2024 | S | 20,000 | $62.50 | Sale −$1,250,000 | 187,377 | Yes | Form 4 |
| Kulkarni SamarthChief Executive Officer | Jan 16, 2024 | Jan 18, 2024 | M · derivative | 20,000 | $19.12 | $382,400 | 59,582 | Yes | Form 4 |
| Kasinger James R.General Counsel and Secretary | Oct 13, 2023 | Oct 17, 2023 | A · derivative | 16,667 | $44.31 | $738,515 | 16,667 | No | Form 4 |
| Kasinger James R.General Counsel and Secretary | Oct 13, 2023 | Oct 17, 2023 | A · derivative | 6,340 | $0.00 | $0 | 6,340 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Oct 13, 2023 | Oct 17, 2023 | A · derivative | 52,500 | $44.31 | $2,326,275 | 52,500 | No | Form 4 |
| Kulkarni SamarthChief Executive Officer | Oct 13, 2023 | Oct 17, 2023 | A · derivative | 25,000 | $0.00 | $0 | 25,000 | No | Form 4 |
| Morrow Phuong KhanhChief Medical Officer | Oct 13, 2023 | Oct 17, 2023 | A · derivative | 16,667 | $44.31 | $738,515 | 16,667 | No | Form 4 |
| Prasad RajuChief Financial Officer | Oct 13, 2023 | Oct 17, 2023 | A · derivative | 13,832 | $44.31 | $612,896 | 13,832 | No | Form 4 |