DYNDyne Therapeutics, Inc.
- Market cap
- $2.92B
- as of 2026-10-23
- Latest close
- $15.62
- as of 2026-10-23
- Sector
- Healthcare
- as of 2026-10-24
- Industry
- Biotechnology
- as of 2026-10-24
Cluster
No cluster in the last 90 days under the default rule (14d · ≥2 insiders · all roles).
Form 4 historysince 2023-11-02
Dashed line = amended filing (Form 4/A)
Showing the latest 500 of 565 transactions.
| Insider | Traded | Filed | Type | Shares | Price | Value | Owned after | 10b5-1 plan | Filing |
|---|---|---|---|---|---|---|---|---|---|
| Kerr DouglasHead of R&D and CMO | Oct 20 | Oct 22 | A | 8,000 | $0.00 | $0 | 170,564 | No | Form 4 |
| Kerr DouglasHead of R&D and CMO | Oct 20 | Oct 22 | A · derivative | 12,000 | $16.27 | $195,240 | 12,000 | No | Form 4 |
| Posner Brian S | Oct 2 | Oct 6 | P | 2,500 | $16.00 | Purchase +$40,000 | 27,000 | No | Form 4 |
| Cox JohnCEO & President | Sep 8 | Sep 8 | S | 5,658 | $18.88 | Sale −$106,823 | 357,507 | Yes | Form 4 |
| Kerr DouglasChief Medical Officer | Sep 8 | Sep 8 | S | 1,290 | $18.88 | Sale −$24,355 | 162,564 | Yes | Form 4 |
| Friedl-Naderer JohannaChief Commercial Officer | Sep 8 | Sep 8 | S | 185 | $18.88 | Sale −$3,493 | 152,897 | Yes | Form 4 |
| Kerr DouglasChief Medical Officer | Sep 4 | Sep 8 | S | 3,745 | $24.35 | Sale −$91,191 | 163,854 | Yes | Form 4 |
| Friedl-Naderer JohannaChief Commercial Officer | Sep 4 | Sep 8 | S | 900 | $24.35 | Sale −$21,915 | 153,082 | Yes | Form 4 |
| Rhodes Jason P | Aug 14 | Aug 17 | S | 1,359,674 | $25.00 | Sale −$33,991,850 | 2,441,454 | Yes | Form 4 |
| Rhodes Jason P | Aug 14 | Aug 17 | S | 478,377 | $25.00 | Sale −$11,959,425 | 567,358 | Yes | Form 4 |
| Rhodes Jason P | Aug 14 | Aug 17 | S | 322,465 | $25.00 | Sale −$8,061,625 | 428,946 | Yes | Form 4 |
| Cox JohnCEO & President | Aug 13 | Aug 17 | S | 4,986 | $26.28 | Sale −$131,032 | 363,165 | Yes | Form 4 |
| Rhodes Jason P | Aug 13 | Aug 17 | S | 268,354 | $26.20 | Sale −$7,030,875 | 3,801,128 | Yes | Form 4 |
| Rhodes Jason P | Aug 13 | Aug 17 | S | 94,415 | $26.20 | Sale −$2,473,673 | 1,045,735 | Yes | Form 4 |
| Rhodes Jason P | Aug 13 | Aug 17 | S | 63,643 | $26.20 | Sale −$1,667,447 | 751,411 | Yes | Form 4 |
| Lucera ErickChief Financial Officer | Aug 13 | Aug 17 | S | 1,797 | $26.28 | Sale −$47,225 | 119,766 | Yes | Form 4 |
| Kerr DouglasChief Medical Officer | Aug 13 | Aug 17 | S | 1,556 | $26.28 | Sale −$40,892 | 167,599 | Yes | Form 4 |
| Friedl-Naderer JohannaChief Commercial Officer | Aug 13 | Aug 17 | S | 226 | $26.28 | Sale −$5,939 | 153,982 | Yes | Form 4 |
| Kersten Dirk | Jul 27 | Jul 29 | S | 256,072 | $25.50 | Sale −$6,529,836 | 3,592,184 | Yes | Form 4 |
| Kersten Dirk | Jul 27 | Jul 29 | S | 5,388 | $26.04 | Sale −$140,304 | 3,586,796 | Yes | Form 4 |
| Rhodes Jason P | Jul 7 | Jul 8 | S | 124,379 | $23.17 | Sale −$2,881,861 | 4,099,069 | Yes | Form 4 |
| Rhodes Jason P | Jul 7 | Jul 8 | S | 29,587 | $23.62 | Sale −$698,845 | 4,069,482 | Yes | Form 4 |
| Rhodes Jason P | Jul 7 | Jul 8 | S | 62,543 | $23.17 | Sale −$1,449,121 | 1,154,994 | Yes | Form 4 |
| Rhodes Jason P | Jul 7 | Jul 8 | S | 14,844 | $23.62 | Sale −$350,615 | 1,140,150 | Yes | Form 4 |
| Rhodes Jason P | Jul 7 | Jul 8 | S | 49,193 | $23.17 | Sale −$1,139,802 | 826,719 | Yes | Form 4 |
| Rhodes Jason P | Jul 7 | Jul 8 | S | 11,665 | $23.62 | Sale −$275,527 | 815,054 | Yes | Form 4 |
| Rhodes Jason P | Jul 7 | Jul 8 | S | 5,000 | $23.61 | Sale −$118,050 | 2,962 | Yes | Form 4 |
| Rhodes Jason P | Jul 6 | Jul 8 | S | 253,039 | $22.79 | Sale −$5,766,759 | 4,223,448 | Yes | Form 4 |
| Rhodes Jason P | Jul 6 | Jul 8 | S | 127,182 | $22.79 | Sale −$2,898,478 | 1,217,537 | Yes | Form 4 |
| Rhodes Jason P | Jul 6 | Jul 8 | S | 100,019 | $22.79 | Sale −$2,279,433 | 875,912 | Yes | Form 4 |
| Rhodes Jason P | Jun 29 | Jun 30 | S | 102,969 | $21.14 | Sale −$2,176,765 | 4,476,487 | Yes | Form 4 |
| Rhodes Jason P | Jun 29 | Jun 30 | S | 51,756 | $21.14 | Sale −$1,094,122 | 1,344,719 | Yes | Form 4 |
| Rhodes Jason P | Jun 29 | Jun 30 | S | 40,702 | $21.14 | Sale −$860,440 | 975,931 | Yes | Form 4 |
| Rhodes Jason P | Jun 26 | Jun 30 | S | 162,954 | $21.28 | Sale −$3,467,661 | 4,579,456 | Yes | Form 4 |
| Rhodes Jason P | Jun 26 | Jun 30 | S | 81,903 | $21.28 | Sale −$1,742,896 | 1,396,475 | Yes | Form 4 |
| Rhodes Jason P | Jun 26 | Jun 30 | S | 64,411 | $21.28 | Sale −$1,370,666 | 1,016,633 | Yes | Form 4 |
| Lucera ErickChief Financial Officer | Jun 25 | Jun 26 | S | 2,362 | $20.37 | Sale −$48,114 | 121,563 | No | Form 4 |
| Rhodes Jason P | Jun 25 | Jun 26 | S | 12,699 | $21.10 | Sale −$267,949 | 4,742,410 | Yes | Form 4 |
| Rhodes Jason P | Jun 25 | Jun 26 | S | 6,382 | $21.10 | Sale −$134,660 | 1,478,378 | Yes | Form 4 |
| Rhodes Jason P | Jun 25 | Jun 26 | S | 5,019 | $21.10 | Sale −$105,901 | 1,081,044 | Yes | Form 4 |
| Rhodes Jason P | Jun 24 | Jun 26 | S | 50,530 | $21.02 | Sale −$1,062,141 | 4,755,109 | Yes | Form 4 |
| Rhodes Jason P | Jun 24 | Jun 26 | S | 25,397 | $21.02 | Sale −$533,845 | 1,484,760 | Yes | Form 4 |
| Rhodes Jason P | Jun 24 | Jun 26 | S | 19,973 | $21.02 | Sale −$419,832 | 1,086,063 | Yes | Form 4 |
| Rhodes Jason P | Jun 23 | Jun 26 | S | 77,855 | $21.13 | Sale −$1,645,076 | 4,805,639 | Yes | Form 4 |
| Rhodes Jason P | Jun 23 | Jun 26 | S | 39,131 | $21.13 | Sale −$826,838 | 1,510,157 | Yes | Form 4 |
| Rhodes Jason P | Jun 23 | Jun 26 | S | 30,774 | $21.13 | Sale −$650,255 | 1,106,036 | Yes | Form 4 |
| Kersten Dirk | Jun 23 | Jun 24 | S | 71,629 | $21.04 | Sale −$1,507,074 | 3,849,913 | Yes | Form 4 |
| Kersten Dirk | Jun 23 | Jun 24 | S | 1,657 | $21.47 | Sale −$35,576 | 3,848,256 | Yes | Form 4 |
| Kersten Dirk | Jun 22 | Jun 24 | S | 190,676 | $20.57 | Sale −$3,922,205 | 3,921,542 | Yes | Form 4 |
| Greene Barry E | Jun 22 | Jun 23 | A · derivative | 57,463 | $20.87 | $1,199,253 | 57,463 | No | Form 4 |
| Kersten Dirk | Jun 18 | Jun 22 | S | 46,901 | $20.07 | Sale −$941,303 | 4,112,218 | Yes | Form 4 |
| Kersten Dirk | Jun 17 | Jun 22 | S | 37,454 | $20.14 | Sale −$754,324 | 4,159,119 | Yes | Form 4 |
| Cox JohnCEO & President | Jun 16 | Jun 17 | S | 2,683 | $18.33 | Sale −$49,179 | 368,151 | Yes | Form 4 |
| Kerr DouglasChief Medical Officer | Jun 16 | Jun 17 | S | 887 | $18.33 | Sale −$16,259 | 169,155 | Yes | Form 4 |
| Friedl-Naderer JohannaChief Commercial Officer | Jun 16 | Jun 17 | S | 145 | $18.33 | Sale −$2,658 | 154,208 | Yes | Form 4 |
| Posner Brian S | Jun 8 | Jun 9 | P | 2,000 | $16.94 | Purchase +$33,880 | 24,500 | No | Form 4 |
| Posner Brian S | Jun 5 | Jun 9 | A · derivative | 35,152 | $17.04 | $598,990 | 35,152 | No | Form 4 |
| Stehman-Breen Catherine | Jun 5 | Jun 9 | A · derivative | 35,152 | $17.04 | $598,990 | 35,152 | No | Form 4 |
| Incerti Carlo | Jun 5 | Jun 9 | A · derivative | 35,152 | $17.04 | $598,990 | 35,152 | No | Form 4 |
| Kersten Dirk | Jun 5 | Jun 9 | A · derivative | 35,152 | $17.04 | $598,990 | 35,152 | No | Form 4 |
| Rhodes Jason P | Jun 5 | Jun 9 | A · derivative | 35,152 | $17.04 | $598,990 | 35,152 | No | Form 4 |
| Lubner David Charles | Jun 5 | Jun 9 | A · derivative | 35,152 | $17.04 | $598,990 | 35,152 | No | Form 4 |
| Hurwitz Edward | Jun 5 | Jun 9 | A · derivative | 35,152 | $17.04 | $598,990 | 35,152 | No | Form 4 |
| Posner Brian S | Jun 3 | Jun 5 | P | 2,500 | $17.48 | Purchase +$43,700 | 22,500 | No | Form 4 |
| Posner Brian S | May 26 | May 28 | P | 2,000 | $18.21 | Purchase +$36,420 | 20,000 | No | Form 4 |
| Posner Brian S | May 20 | May 22 | P | 2,500 | $17.12 | Purchase +$42,800 | 18,000 | No | Form 4 |
| Cox JohnCEO & President | May 13 | May 14 | S | 3,311 | $18.36 | Sale −$60,790 | 370,834 | Yes | Form 4 |
| Lucera ErickChief Financial Officer | May 13 | May 14 | S | 1,448 | $18.36 | Sale −$26,585 | 123,925 | Yes | Form 4 |
| Kerr DouglasChief Medical Officer | May 13 | May 14 | S | 1,564 | $18.36 | Sale −$28,715 | 170,042 | Yes | Form 4 |
| Friedl-Naderer JohannaChief Commercial Officer | May 13 | May 14 | S | 228 | $18.36 | Sale −$4,186 | 154,353 | Yes | Form 4 |
| Rhodes Jason P | May 6 | May 6 | S | 21,926 | $18.18 | Sale −$398,615 | 1,549,288 | Yes | Form 4 |
| Rhodes Jason P | May 6 | May 6 | S | 43,621 | $18.18 | Sale −$793,030 | 4,883,494 | Yes | Form 4 |
| Rhodes Jason P | May 6 | May 6 | S | 428 | $18.18 | Sale −$7,781 | 7,962 | Yes | Form 4 |
| Rhodes Jason P | May 6 | May 6 | S | 17,244 | $18.18 | Sale −$313,496 | 1,136,810 | Yes | Form 4 |
| Rhodes Jason P | May 5 | May 6 | S | 3,056 | $18.03 | Sale −$55,100 | 1,571,214 | Yes | Form 4 |
| Rhodes Jason P | May 5 | May 6 | S | 6,081 | $18.03 | Sale −$109,640 | 4,927,115 | Yes | Form 4 |
| Rhodes Jason P | May 5 | May 6 | S | 60 | $18.03 | Sale −$1,082 | 8,390 | Yes | Form 4 |
| Rhodes Jason P | May 5 | May 6 | S | 2,403 | $18.03 | Sale −$43,326 | 1,154,054 | Yes | Form 4 |
| Rhodes Jason P | May 4 | May 6 | S | 3,136 | $18.00 | Sale −$56,448 | 1,574,270 | Yes | Form 4 |
| Rhodes Jason P | May 4 | May 6 | S | 6,241 | $18.00 | Sale −$112,338 | 4,933,196 | Yes | Form 4 |
| Rhodes Jason P | May 4 | May 6 | S | 61 | $18.00 | Sale −$1,098 | 8,450 | Yes | Form 4 |
| Rhodes Jason P | May 4 | May 6 | S | 2,466 | $18.00 | Sale −$44,388 | 1,156,457 | Yes | Form 4 |
| Rhodes Jason P | Apr 28 | Apr 30 | S | 59,870 | $18.38 | Sale −$1,100,411 | 1,577,432 | Yes | Form 4 |
| Rhodes Jason P | Apr 28 | Apr 30 | S | 119,115 | $18.38 | Sale −$2,189,334 | 4,939,489 | Yes | Form 4 |
| Rhodes Jason P | Apr 28 | Apr 30 | S | 1,170 | $18.38 | Sale −$21,505 | 8,512 | Yes | Form 4 |
| Rhodes Jason P | Apr 28 | Apr 30 | S | 47,082 | $18.38 | Sale −$865,367 | 1,158,944 | Yes | Form 4 |
| Rhodes Jason P | Apr 28 | Apr 30 | S | 26 | $19.00 | Sale −$494 | 1,577,406 | Yes | Form 4 |
| Rhodes Jason P | Apr 28 | Apr 30 | S | 52 | $19.00 | Sale −$988 | 4,939,437 | Yes | Form 4 |
| Rhodes Jason P | Apr 28 | Apr 30 | S | 1 | $19.00 | Sale −$19 | 8,511 | Yes | Form 4 |
| Rhodes Jason P | Apr 28 | Apr 30 | S | 21 | $19.00 | Sale −$399 | 1,158,923 | Yes | Form 4 |
| Lubner David Charles | Apr 24 | Apr 28 | G | 53,625 | $0.00 | $0 | not reported | No | Form 4 |
| Rhodes Jason P | Apr 27 | Apr 27 | S | 45,709 | $18.15 | Sale −$829,618 | 1,637,302 | Yes | Form 4 |
| Rhodes Jason P | Apr 27 | Apr 27 | S | 90,943 | $18.15 | Sale −$1,650,615 | 5,058,604 | Yes | Form 4 |
| Rhodes Jason P | Apr 27 | Apr 27 | S | 894 | $18.15 | Sale −$16,226 | 9,682 | Yes | Form 4 |
| Rhodes Jason P | Apr 27 | Apr 27 | S | 35,947 | $18.15 | Sale −$652,438 | 1,206,026 | Yes | Form 4 |
| Rhodes Jason P | Apr 24 | Apr 27 | S | 36,345 | $18.48 | Sale −$671,656 | 1,683,011 | Yes | Form 4 |
| Rhodes Jason P | Apr 24 | Apr 27 | S | 72,310 | $18.48 | Sale −$1,336,289 | 5,149,547 | Yes | Form 4 |
| Rhodes Jason P | Apr 24 | Apr 27 | S | 710 | $18.48 | Sale −$13,121 | 10,576 | Yes | Form 4 |
| Rhodes Jason P | Apr 24 | Apr 27 | S | 28,583 | $18.48 | Sale −$528,214 | 1,241,973 | Yes | Form 4 |
| Rhodes Jason P | Apr 23 | Apr 27 | S | 19,261 | $19.19 | Sale −$369,619 | 1,719,356 | Yes | Form 4 |
| Rhodes Jason P | Apr 23 | Apr 27 | S | 38,322 | $19.19 | Sale −$735,399 | 5,221,857 | Yes | Form 4 |
| Rhodes Jason P | Apr 23 | Apr 27 | S | 377 | $19.19 | Sale −$7,235 | 11,286 | Yes | Form 4 |
| Rhodes Jason P | Apr 23 | Apr 27 | S | 15,148 | $19.19 | Sale −$290,690 | 1,270,556 | Yes | Form 4 |
| Kersten Dirk | Apr 22 | Apr 23 | S | 2,652 | $20.00 | Sale −$53,040 | 4,196,573 | Yes | Form 4 |
| Kersten Dirk | Apr 21 | Apr 23 | S | 8,300 | $20.01 | Sale −$166,083 | 4,199,225 | Yes | Form 4 |
| Rhodes Jason P | Apr 22 | Apr 22 | S | 75,866 | $19.68 | Sale −$1,493,043 | 1,738,617 | Yes | Form 4 |
| Rhodes Jason P | Apr 22 | Apr 22 | S | 150,942 | $19.68 | Sale −$2,970,539 | 5,260,179 | Yes | Form 4 |
| Rhodes Jason P | Apr 22 | Apr 22 | S | 1,485 | $19.68 | Sale −$29,225 | 11,663 | Yes | Form 4 |
| Rhodes Jason P | Apr 22 | Apr 22 | S | 59,663 | $19.68 | Sale −$1,174,168 | 1,285,704 | Yes | Form 4 |
| Rhodes Jason P | Apr 21 | Apr 22 | S | 71,499 | $19.51 | Sale −$1,394,945 | 1,815,252 | Yes | Form 4 |
| Rhodes Jason P | Apr 21 | Apr 22 | S | 142,253 | $19.51 | Sale −$2,775,356 | 5,412,651 | Yes | Form 4 |
| Rhodes Jason P | Apr 21 | Apr 22 | S | 1,398 | $19.51 | Sale −$27,275 | 13,163 | Yes | Form 4 |
| Rhodes Jason P | Apr 21 | Apr 22 | S | 56,228 | $19.51 | Sale −$1,097,008 | 1,345,972 | Yes | Form 4 |
| Rhodes Jason P | Apr 21 | Apr 22 | S | 769 | $20.05 | Sale −$15,418 | 1,814,483 | Yes | Form 4 |
| Rhodes Jason P | Apr 21 | Apr 22 | S | 1,530 | $20.05 | Sale −$30,677 | 5,411,121 | Yes | Form 4 |
| Rhodes Jason P | Apr 21 | Apr 22 | S | 15 | $20.05 | Sale −$301 | 13,148 | Yes | Form 4 |
| Rhodes Jason P | Apr 21 | Apr 22 | S | 605 | $20.05 | Sale −$12,130 | 1,345,367 | Yes | Form 4 |
| Rhodes Jason P | Apr 20 | Apr 22 | S | 71,676 | $20.06 | Sale −$1,437,821 | 1,886,751 | Yes | Form 4 |
| Rhodes Jason P | Apr 20 | Apr 22 | S | 142,604 | $20.06 | Sale −$2,860,636 | 5,554,904 | Yes | Form 4 |
| Rhodes Jason P | Apr 20 | Apr 22 | S | 1,401 | $20.06 | Sale −$28,104 | 14,561 | Yes | Form 4 |
| Rhodes Jason P | Apr 20 | Apr 22 | S | 56,368 | $20.06 | Sale −$1,130,742 | 1,402,200 | Yes | Form 4 |
| Kersten Dirk | Apr 20 | Apr 21 | S | 125,274 | $20.07 | Sale −$2,514,249 | 4,207,525 | Yes | Form 4 |
| Kersten Dirk | Apr 17 | Apr 21 | S | 211,974 | $20.29 | Sale −$4,300,952 | 4,332,799 | Yes | Form 4 |
| Kersten Dirk | Apr 16 | Apr 17 | S | 11,116 | $21.10 | Sale −$234,548 | 4,551,430 | Yes | Form 4 |
| Kersten Dirk | Apr 16 | Apr 17 | S | 6,657 | $20.06 | Sale −$133,539 | 4,544,773 | Yes | Form 4 |
| Kersten Dirk | Apr 15 | Apr 17 | S | 81,840 | $20.27 | Sale −$1,658,897 | 4,562,546 | Yes | Form 4 |
| Lucera ErickChief Financial Officer | Apr 1 | Apr 3 | S | 5,727 | $18.64 | Sale −$106,751 | 125,373 | Yes | Form 4 |
| Posner Brian S | Mar 30 | Apr 1 | P | 2,000 | $17.08 | Purchase +$34,160 | 15,500 | No | Form 4 |
| Kersten Dirk | Mar 11 | Mar 13 | S | 129,672 | $19.52 | Sale −$2,531,197 | 4,644,386 | Yes | Form 4 |
| Posner Brian S | Mar 11 | Mar 13 | P | 2,000 | $19.35 | Purchase +$38,700 | 13,500 | No | Form 4 |
| Kersten Dirk | Mar 10 | Mar 11 | S | 9,482 | $18.21 | Sale −$172,667 | 5,275,674 | Yes | Form 4 |
| Kersten Dirk | Mar 10 | Mar 11 | S | 219,758 | $19.33 | Sale −$4,247,922 | 5,055,916 | Yes | Form 4 |
| Kersten Dirk | Mar 10 | Mar 11 | S | 281,858 | $19.80 | Sale −$5,580,788 | 4,774,058 | Yes | Form 4 |
| Kersten Dirk | Mar 9 | Mar 11 | S | 177,690 | $17.72 | Sale −$3,148,667 | 5,285,156 | Yes | Form 4 |
| Posner Brian S | Mar 6 | Mar 10 | P | 3,000 | $15.06 | Purchase +$45,180 | 11,500 | No | Form 4 |
| Cox JohnCEO & President | Mar 5 | Mar 6 | S | 2,732 | $14.90 | Sale −$40,707 | 374,145 | Yes | Form 4 |
| Kerr DouglasChief Medical Officer | Mar 5 | Mar 6 | S | 904 | $14.90 | Sale −$13,470 | 171,606 | Yes | Form 4 |
| Friedl-Naderer JohannaChief Commercial Officer | Mar 5 | Mar 6 | S | 148 | $14.90 | Sale −$2,205 | 154,581 | Yes | Form 4 |
| Lucera ErickChief Financial Officer | Feb 12 | Feb 17 | A | 65,000 | $0.00 | $0 | 131,100 | No | Form 4 |
| Lucera ErickChief Financial Officer | Feb 12 | Feb 17 | A · derivative | 105,000 | $16.00 | $1,680,000 | 105,000 | No | Form 4 |
| Friedl-Naderer JohannaChief Commercial Officer | Feb 12 | Feb 17 | A | 60,000 | $0.00 | $0 | 154,729 | No | Form 4 |
| Friedl-Naderer JohannaChief Commercial Officer | Feb 12 | Feb 17 | A · derivative | 90,000 | $16.00 | $1,440,000 | 90,000 | No | Form 4 |
| Kerr DouglasChief Medical Officer | Feb 12 | Feb 17 | A | 85,000 | $0.00 | $0 | 172,510 | No | Form 4 |
| Kerr DouglasChief Medical Officer | Feb 12 | Feb 17 | A · derivative | 130,000 | $16.00 | $2,080,000 | 130,000 | No | Form 4 |
| Cox JohnCEO & President | Feb 12 | Feb 17 | A | 180,000 | $0.00 | $0 | 376,877 | No | Form 4 |
| Cox JohnCEO & President | Feb 12 | Feb 17 | A · derivative | 285,000 | $16.00 | $4,560,000 | 285,000 | No | Form 4 |
| Karnani Vikram | Dec 22, 2025 | Dec 23, 2025 | A · derivative | 59,665 | $20.78 | $1,239,839 | 59,665 | No | Form 4 |
| Friedl-Naderer JohannaChief Commercial Officer | Dec 5, 2025 | Dec 5, 2025 | S | 144 | $20.72 | Sale −$2,984 | 94,729 | Yes | Form 4 |
| Kerr DouglasChief Medical Officer | Dec 5, 2025 | Dec 5, 2025 | S | 880 | $20.72 | Sale −$18,234 | 87,510 | Yes | Form 4 |
| Cox JohnCEO & President | Dec 5, 2025 | Dec 5, 2025 | S | 2,662 | $20.72 | Sale −$55,157 | 196,877 | Yes | Form 4 |
| Posner Brian S | Oct 1, 2025 | Oct 2, 2025 | A · derivative | 70,000 | $12.50 | $875,000 | 70,000 | No | Form 4 |
| Cox JohnCEO & President | Sep 5, 2025 | Sep 9, 2025 | S | 2,640 | $13.41 | Sale −$35,402 | 199,539 | Yes | Form 4 |
| Kerr DouglasChief Medical Officer | Sep 5, 2025 | Sep 8, 2025 | S | 873 | $13.41 | Sale −$11,707 | 88,390 | Yes | Form 4 |
| Friedl-Naderer JohannaChief Commercial Officer | Sep 5, 2025 | Sep 8, 2025 | S | 144 | $13.41 | Sale −$1,931 | 94,873 | Yes | Form 4 |
| Kerr DouglasChief Medical Officer | Sep 4, 2025 | Sep 8, 2025 | S | 3,552 | $13.27 | Sale −$47,135 | 89,263 | Yes | Form 4 |
| Friedl-Naderer JohannaChief Commercial Officer | Sep 4, 2025 | Sep 8, 2025 | S | 894 | $13.27 | Sale −$11,863 | 95,017 | Yes | Form 4 |
| Cox JohnCEO & President | Jul 16, 2025 | Jul 18, 2025 | A · derivative | 197,285 | $9.33 | $1,840,669 | 197,285 | No | Form 4 |
| Kerr DouglasChief Medical Officer | Jul 16, 2025 | Jul 18, 2025 | A · derivative | 65,110 | $9.33 | $607,476 | 65,110 | No | Form 4 |
| Friedl-Naderer JohannaChief Commercial Officer | Jul 16, 2025 | Jul 18, 2025 | A · derivative | 51,255 | $9.33 | $478,209 | 51,255 | No | Form 4 |
| Cox JohnCEO & President | Jul 15, 2025 | Jul 15, 2025 | G | 10,000 | $0.00 | $0 | 232,179 | No | Form 4 |
| Cox JohnCEO & President | Jul 15, 2025 | Jul 15, 2025 | G | 10,000 | $0.00 | $0 | 222,179 | No | Form 4 |
| Cox JohnCEO & President | Jul 15, 2025 | Jul 15, 2025 | G | 10,000 | $0.00 | $0 | 212,179 | No | Form 4 |
| Cox JohnCEO & President | Jul 15, 2025 | Jul 15, 2025 | G | 10,000 | $0.00 | $0 | 202,179 | No | Form 4 |
| Cox JohnCEO & President | Jul 14, 2025 | Jul 15, 2025 | P | 100,000 | $9.11 | Purchase +$911,000 | 242,179 | No | Form 4 |
| Friedl-Naderer JohannaChief Commercial Officer | Jun 5, 2025 | Jun 6, 2025 | S | 146 | $13.35 | Sale −$1,949 | 95,911 | Yes | Form 4 |
| Kerr DouglasChief Medical Officer | Jun 5, 2025 | Jun 6, 2025 | S | 1,342 | $13.35 | Sale −$17,916 | 92,815 | Yes | Form 4 |
| Cox JohnCEO & President | Jun 5, 2025 | Jun 6, 2025 | S | 4,060 | $13.35 | Sale −$54,201 | 142,179 | Yes | Form 4 |
| Stehman-Breen Catherine | May 30, 2025 | Jun 3, 2025 | A · derivative | 35,000 | $11.96 | $418,600 | 35,000 | No | Form 4 |
| Incerti Carlo | May 30, 2025 | Jun 3, 2025 | A · derivative | 35,000 | $11.96 | $418,600 | 35,000 | No | Form 4 |
| Kersten Dirk | May 30, 2025 | Jun 3, 2025 | A · derivative | 35,000 | $11.96 | $418,600 | 35,000 | No | Form 4 |
| Rhodes Jason P | May 30, 2025 | Jun 3, 2025 | A · derivative | 35,000 | $11.96 | $418,600 | 35,000 | No | Form 4 |
| Lubner David Charles | May 30, 2025 | Jun 3, 2025 | A · derivative | 35,000 | $11.96 | $418,600 | 35,000 | No | Form 4 |
| Hurwitz Edward | May 30, 2025 | Jun 3, 2025 | A · derivative | 35,000 | $11.96 | $418,600 | 35,000 | No | Form 4 |
| Lucera ErickChief Financial Officer | Mar 31, 2025 | Apr 1, 2025 | A | 66,100 | $0.00 | $0 | 66,100 | No | Form 4 |
| Lucera ErickChief Financial Officer | Mar 31, 2025 | Apr 1, 2025 | A · derivative | 214,500 | $10.46 | $2,243,670 | 214,500 | No | Form 4 |
| Friedl-Naderer JohannaChief Commercial Officer | Mar 13, 2025 | Mar 13, 2025 | S | 143 | $12.12 | Sale −$1,733 | 96,057 | Yes | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | Mar 11, 2025 | Mar 13, 2025 | S | 2,153 | $11.38 | Sale −$24,501 | 195,840 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Mar 11, 2025 | Mar 13, 2025 | S | 1,343 | $11.38 | Sale −$15,283 | 122,330 | Yes | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | Mar 5, 2025 | Mar 7, 2025 | S | 1,094 | $11.83 | Sale −$12,942 | 197,993 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Mar 5, 2025 | Mar 7, 2025 | S | 917 | $11.83 | Sale −$10,848 | 123,673 | Yes | Form 4 |
| Cox JohnCEO & President | Mar 5, 2025 | Mar 7, 2025 | S | 4,061 | $11.83 | Sale −$48,042 | 146,239 | Yes | Form 4 |
| Kerr DouglasChief Medical Officer | Mar 5, 2025 | Mar 7, 2025 | S | 1,343 | $11.83 | Sale −$15,888 | 94,157 | Yes | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | Feb 18, 2025 | Feb 25, 2025 | S | 2,598 | $13.95 | Sale −$36,242 | 199,087 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Feb 18, 2025 | Feb 18, 2025 | S | 2,488 | $13.95 | Sale −$34,708 | 124,590 | Yes | Form 4 |
| Rhodes Jason P | Jan 27, 2025 | Jan 29, 2025 | A | 1,111,111 | $13.50 | $14,999,999 | 1,958,427 | No | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Dec 11, 2024 | Dec 11, 2024 | S | 1,455 | $28.12 | Sale −$40,915 | 127,078 | Yes | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | Dec 11, 2024 | Dec 11, 2024 | S | 2,334 | $28.12 | Sale −$65,632 | 201,685 | Yes | Form 4 |
| Kersten Dirk | Dec 9, 2024 | Dec 10, 2024 | S | 34,437 | $29.18 | Sale −$1,004,872 | 5,400,545 | No | Form 4 |
| Kersten Dirk | Dec 6, 2024 | Dec 10, 2024 | S | 101,675 | $29.34 | Sale −$2,983,145 | 5,434,982 | No | Form 4 |
| Kersten Dirk | Dec 5, 2024 | Dec 6, 2024 | S | 3,806 | $29.05 | Sale −$110,564 | 5,536,657 | No | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | Dec 4, 2024 | Dec 6, 2024 | A | 39,100 | $0.00 | $0 | 176,619 | No | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | Dec 4, 2024 | Dec 6, 2024 | A | 27,400 | $0.00 | $0 | 204,019 | No | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | Dec 4, 2024 | Dec 6, 2024 | A · derivative | 62,400 | $29.44 | $1,837,056 | 62,400 | No | Form 4 |
| Cox JohnCEO & President | Dec 4, 2024 | Dec 6, 2024 | A | 145,300 | $0.00 | $0 | 150,300 | No | Form 4 |
| Cox JohnCEO & President | Dec 4, 2024 | Dec 6, 2024 | A · derivative | 232,100 | $29.44 | $6,833,024 | 232,100 | No | Form 4 |
| Kerr DouglasChief Medical Officer | Dec 4, 2024 | Dec 6, 2024 | A | 48,000 | $0.00 | $0 | 95,500 | No | Form 4 |
| Kerr DouglasChief Medical Officer | Dec 4, 2024 | Dec 6, 2024 | A · derivative | 76,600 | $29.44 | $2,255,104 | 76,600 | No | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Dec 4, 2024 | Dec 6, 2024 | A | 32,700 | $0.00 | $0 | 128,533 | No | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Dec 4, 2024 | Dec 6, 2024 | A · derivative | 52,300 | $29.44 | $1,539,712 | 52,300 | No | Form 4 |
| Kersten Dirk | Dec 4, 2024 | Dec 6, 2024 | S | 135,039 | $29.39 | Sale −$3,968,796 | 5,540,463 | No | Form 4 |
| Friedl-Naderer JohannaChief Commercial Officer | Dec 4, 2024 | Dec 6, 2024 | A | 37,800 | $0.00 | $0 | 96,200 | No | Form 4 |
| Friedl-Naderer JohannaChief Commercial Officer | Dec 4, 2024 | Dec 6, 2024 | A · derivative | 60,300 | $29.44 | $1,775,232 | 60,300 | No | Form 4 |
| Kersten Dirk | Dec 3, 2024 | Dec 4, 2024 | S | 29,732 | $29.05 | Sale −$863,715 | 5,675,502 | No | Form 4 |
| Kersten Dirk | Dec 2, 2024 | Dec 4, 2024 | S | 79,973 | $29.66 | Sale −$2,371,999 | 5,706,462 | No | Form 4 |
| Kersten Dirk | Dec 2, 2024 | Dec 4, 2024 | S | 1,228 | $30.37 | Sale −$37,294 | 5,705,234 | No | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | Nov 18, 2024 | Nov 18, 2024 | S | 2,856 | $28.20 | Sale −$80,539 | 137,519 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Nov 18, 2024 | Nov 18, 2024 | S | 2,735 | $28.20 | Sale −$77,127 | 95,833 | Yes | Form 4 |
| Incerti Carlo | Nov 18, 2024 | Nov 18, 2024 | M | 16,500 | $8.69 | $143,385 | 16,500 | No | Form 4 |
| Incerti Carlo | Nov 18, 2024 | Nov 18, 2024 | S | 16,500 | $28.73 | Sale −$474,045 | not reported | No | Form 4 |
| Incerti Carlo | Nov 18, 2024 | Nov 18, 2024 | M · derivative | 16,500 | $8.69 | $143,385 | 22,693 | No | Form 4 |
| Rhodes Jason P | Nov 14, 2024 | Nov 18, 2024 | S | 583 | $33.10 | Sale −$19,297 | 5,697,508 | No | Form 4 |
| Rhodes Jason P | Nov 14, 2024 | Nov 18, 2024 | S | 4 | $33.10 | Sale −$132 | 15,962 | No | Form 4 |
| Rhodes Jason P | Nov 14, 2024 | Nov 18, 2024 | S | 123 | $33.10 | Sale −$4,071 | 1,458,568 | No | Form 4 |
| Rhodes Jason P | Nov 14, 2024 | Nov 18, 2024 | S | 72 | $33.10 | Sale −$2,383 | 847,316 | No | Form 4 |
| Kersten Dirk | Nov 14, 2024 | Nov 15, 2024 | S | 8,929 | $32.82 | Sale −$293,050 | 5,786,435 | Yes | Form 4 |
| Kersten Dirk | Nov 13, 2024 | Nov 15, 2024 | S | 10,803 | $35.24 | Sale −$380,698 | 62,301 | Yes | Form 4 |
| Kersten Dirk | Oct 21, 2024 | Oct 22, 2024 | S | 121 | $35.06 | Sale −$4,242 | 73,104 | Yes | Form 4 |
| Kersten Dirk | Oct 18, 2024 | Oct 22, 2024 | S | 13,414 | $35.16 | Sale −$471,636 | 73,225 | Yes | Form 4 |
| Kersten Dirk | Oct 17, 2024 | Oct 18, 2024 | S | 13,013 | $35.17 | Sale −$457,667 | 86,639 | Yes | Form 4 |
| Kersten Dirk | Oct 16, 2024 | Oct 18, 2024 | S | 23,671 | $35.35 | Sale −$836,770 | 99,652 | Yes | Form 4 |
| Kersten Dirk | Oct 3, 2024 | Oct 7, 2024 | S | 5,441 | $35.13 | Sale −$191,142 | 123,323 | Yes | Form 4 |
| Kersten Dirk | Oct 2, 2024 | Oct 3, 2024 | S | 21,518 | $35.38 | Sale −$761,307 | 128,764 | Yes | Form 4 |
| Kersten Dirk | Oct 1, 2024 | Oct 3, 2024 | S | 8,423 | $35.16 | Sale −$296,153 | 150,282 | Yes | Form 4 |
| Kersten Dirk | Sep 30, 2024 | Oct 1, 2024 | S | 29,007 | $35.47 | Sale −$1,028,878 | 160,640 | Yes | Form 4 |
| Kersten Dirk | Sep 30, 2024 | Oct 1, 2024 | S | 1,935 | $36.02 | Sale −$69,699 | 158,705 | Yes | Form 4 |
| Kersten Dirk | Sep 27, 2024 | Oct 1, 2024 | S | 32 | $35.00 | Sale −$1,120 | 189,647 | Yes | Form 4 |
| Kersten Dirk | Sep 26, 2024 | Sep 27, 2024 | S | 1,260 | $35.29 | Sale −$44,465 | 189,679 | Yes | Form 4 |
| Kersten Dirk | Sep 25, 2024 | Sep 27, 2024 | S | 2,357 | $35.06 | Sale −$82,636 | 190,939 | Yes | Form 4 |
| Kersten Dirk | Sep 23, 2024 | Sep 24, 2024 | S | 36,221 | $35.19 | Sale −$1,274,617 | 197,906 | Yes | Form 4 |
| Kersten Dirk | Sep 23, 2024 | Sep 24, 2024 | S | 4,610 | $36.33 | Sale −$167,481 | 193,296 | Yes | Form 4 |
| Kersten Dirk | Sep 20, 2024 | Sep 24, 2024 | S | 78,940 | $36.45 | Sale −$2,877,363 | 234,598 | Yes | Form 4 |
| Kersten Dirk | Sep 20, 2024 | Sep 24, 2024 | S | 471 | $37.01 | Sale −$17,432 | 234,127 | Yes | Form 4 |
| Kersten Dirk | Sep 19, 2024 | Sep 20, 2024 | S | 27,767 | $35.74 | Sale −$992,393 | 364,510 | Yes | Form 4 |
| Kersten Dirk | Sep 19, 2024 | Sep 20, 2024 | S | 50,972 | $36.41 | Sale −$1,855,891 | 313,538 | Yes | Form 4 |
| Kersten Dirk | Sep 18, 2024 | Sep 20, 2024 | S | 1,554 | $35.03 | Sale −$54,437 | 392,277 | Yes | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | Sep 18, 2024 | Sep 19, 2024 | S | 2,339 | $34.55 | Sale −$80,812 | 140,375 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Sep 18, 2024 | Sep 19, 2024 | S | 1,390 | $34.55 | Sale −$48,025 | 98,568 | Yes | Form 4 |
| High Susanna GattiChief Operating Officer | Sep 18, 2024 | Sep 19, 2024 | S | 4,340 | $34.41 | Sale −$149,339 | 136,272 | Yes | Form 4 |
| High Susanna GattiChief Operating Officer | Sep 18, 2024 | Sep 19, 2024 | S | 4,636 | $34.41 | Sale −$159,525 | 131,636 | Yes | Form 4 |
| Kersten Dirk | Sep 17, 2024 | Sep 18, 2024 | S | 3,272 | $35.13 | Sale −$114,945 | 393,831 | Yes | Form 4 |
| Kersten Dirk | Sep 16, 2024 | Sep 18, 2024 | S | 1,320 | $35.04 | Sale −$46,253 | 397,103 | Yes | Form 4 |
| High Susanna GattiChief Operating Officer | Sep 11, 2024 | Sep 11, 2024 | S | 2,548 | $31.89 | Sale −$81,256 | 143,334 | Yes | Form 4 |
| High Susanna GattiChief Operating Officer | Sep 11, 2024 | Sep 11, 2024 | S | 2,722 | $31.89 | Sale −$86,805 | 140,612 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Sep 11, 2024 | Sep 11, 2024 | S | 1,468 | $31.89 | Sale −$46,815 | 99,958 | Yes | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | Sep 11, 2024 | Sep 11, 2024 | S | 2,161 | $31.89 | Sale −$68,914 | 142,714 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Sep 6, 2024 | Sep 10, 2024 | M | 6,502 | $5.54 | $36,021 | 117,524 | No | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Sep 6, 2024 | Sep 10, 2024 | M | 3,353 | $5.54 | $18,576 | 120,877 | No | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Sep 6, 2024 | Sep 10, 2024 | M | 34,833 | $19.00 | $661,827 | 155,710 | No | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Sep 6, 2024 | Sep 10, 2024 | M | 16,696 | $13.12 | $219,052 | 172,406 | No | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Sep 6, 2024 | Sep 10, 2024 | M | 29,792 | $8.58 | $255,615 | 202,198 | No | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Sep 6, 2024 | Sep 10, 2024 | M | 18,750 | $10.72 | $201,000 | 220,948 | No | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Sep 6, 2024 | Sep 10, 2024 | M | 6,552 | $10.88 | $71,286 | 227,500 | No | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Sep 6, 2024 | Sep 10, 2024 | S | 124,374 | $32.14 | Sale −$3,997,380 | 103,126 | No | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Sep 6, 2024 | Sep 10, 2024 | S | 1,700 | $32.63 | Sale −$55,471 | 101,426 | No | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Sep 6, 2024 | Sep 10, 2024 | M · derivative | 6,502 | $5.54 | $36,021 | not reported | No | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Sep 6, 2024 | Sep 10, 2024 | M · derivative | 3,353 | $5.54 | $18,576 | not reported | No | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Sep 6, 2024 | Sep 10, 2024 | M · derivative | 34,833 | $19.00 | $661,827 | 742 | No | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Sep 6, 2024 | Sep 10, 2024 | M · derivative | 16,696 | $13.12 | $219,052 | 8,348 | No | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Sep 6, 2024 | Sep 10, 2024 | M · derivative | 29,792 | $8.58 | $255,615 | 25,208 | No | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Sep 6, 2024 | Sep 10, 2024 | M · derivative | 18,750 | $10.72 | $201,000 | 26,250 | No | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Sep 6, 2024 | Sep 10, 2024 | M · derivative | 6,552 | $10.88 | $71,286 | 28,394 | No | Form 4 |
| Kersten Dirk | Sep 5, 2024 | Sep 9, 2024 | S | 1,577 | $35.03 | Sale −$55,242 | 398,423 | Yes | Form 4 |
| Cox JohnCEO & President | Sep 4, 2024 | Sep 4, 2024 | P | 800 | $32.57 | Purchase +$26,056 | 800 | No | Form 4 |
| Cox JohnCEO & President | Sep 4, 2024 | Sep 4, 2024 | P | 7,200 | $33.09 | Purchase +$238,248 | 8,000 | No | Form 4 |
| Cox JohnCEO & President | Sep 4, 2024 | Sep 4, 2024 | P | 800 | $32.57 | Purchase +$26,056 | 800 | No | Form 4 |
| Cox JohnCEO & President | Sep 4, 2024 | Sep 4, 2024 | P | 7,200 | $33.09 | Purchase +$238,248 | 8,000 | No | Form 4 |
| Cox JohnCEO & President | Sep 4, 2024 | Sep 4, 2024 | P | 800 | $32.57 | Purchase +$26,056 | 800 | No | Form 4 |
| Cox JohnCEO & President | Sep 4, 2024 | Sep 4, 2024 | P | 7,200 | $33.09 | Purchase +$238,248 | 8,000 | No | Form 4 |
| Cox JohnCEO & President | Sep 4, 2024 | Sep 4, 2024 | P | 800 | $32.57 | Purchase +$26,056 | 800 | No | Form 4 |
| Cox JohnCEO & President | Sep 4, 2024 | Sep 4, 2024 | P | 7,200 | $33.09 | Purchase +$238,248 | 8,000 | No | Form 4 |
| Kersten Dirk | Aug 30, 2024 | Sep 4, 2024 | S | 25,096 | $45.49 | Sale −$1,141,617 | 406,204 | Yes | Form 4 |
| Kersten Dirk | Aug 30, 2024 | Sep 4, 2024 | S | 6,204 | $46.01 | Sale −$285,446 | 400,000 | Yes | Form 4 |
| Friedl-Naderer JohannaChief Commercial Officer | Sep 3, 2024 | Sep 3, 2024 | A | 58,400 | $0.00 | $0 | 58,400 | No | Form 4 |
| Friedl-Naderer JohannaChief Commercial Officer | Sep 3, 2024 | Sep 3, 2024 | A · derivative | 185,300 | $31.94 | $5,918,482 | 185,300 | No | Form 4 |
| Kerr DouglasChief Medical Officer | Sep 3, 2024 | Sep 3, 2024 | A | 47,500 | $0.00 | $0 | 47,500 | No | Form 4 |
| Kerr DouglasChief Medical Officer | Sep 3, 2024 | Sep 3, 2024 | A · derivative | 150,300 | $31.94 | $4,800,582 | 150,300 | No | Form 4 |
| Kersten Dirk | Aug 29, 2024 | Aug 30, 2024 | S | 45,640 | $45.19 | Sale −$2,062,472 | 442,068 | Yes | Form 4 |
| Kersten Dirk | Aug 29, 2024 | Aug 30, 2024 | S | 10,768 | $45.81 | Sale −$493,282 | 431,300 | Yes | Form 4 |
| Kersten Dirk | Aug 28, 2024 | Aug 30, 2024 | S | 16,386 | $44.41 | Sale −$727,702 | 549,175 | Yes | Form 4 |
| Kersten Dirk | Aug 28, 2024 | Aug 30, 2024 | S | 61,467 | $44.94 | Sale −$2,762,327 | 487,708 | Yes | Form 4 |
| Kersten Dirk | Aug 27, 2024 | Aug 28, 2024 | S | 65,403 | $44.28 | Sale −$2,896,045 | 565,561 | Yes | Form 4 |
| Kersten Dirk | Aug 26, 2024 | Aug 28, 2024 | S | 77,963 | $45.23 | Sale −$3,526,266 | 642,498 | Yes | Form 4 |
| Kersten Dirk | Aug 26, 2024 | Aug 28, 2024 | S | 11,534 | $45.79 | Sale −$528,142 | 630,964 | Yes | Form 4 |
| Kersten Dirk | Aug 23, 2024 | Aug 26, 2024 | S | 20,955 | $45.82 | Sale −$960,158 | 784,594 | Yes | Form 4 |
| Kersten Dirk | Aug 23, 2024 | Aug 26, 2024 | S | 64,133 | $46.37 | Sale −$2,973,847 | 720,461 | Yes | Form 4 |
| Kersten Dirk | Aug 22, 2024 | Aug 26, 2024 | S | 94,908 | $45.82 | Sale −$4,348,685 | 805,962 | Yes | Form 4 |
| Kersten Dirk | Aug 22, 2024 | Aug 26, 2024 | S | 413 | $46.97 | Sale −$19,399 | 805,549 | Yes | Form 4 |
| Kersten Dirk | Aug 21, 2024 | Aug 22, 2024 | S | 64,518 | $46.52 | Sale −$3,001,377 | 972,115 | Yes | Form 4 |
| Kersten Dirk | Aug 21, 2024 | Aug 22, 2024 | S | 71,245 | $47.01 | Sale −$3,349,227 | 900,870 | Yes | Form 4 |
| Kersten Dirk | Aug 20, 2024 | Aug 22, 2024 | S | 43,057 | $45.68 | Sale −$1,966,844 | 1,080,416 | Yes | Form 4 |
| Kersten Dirk | Aug 20, 2024 | Aug 22, 2024 | S | 35,457 | $46.94 | Sale −$1,664,352 | 1,044,959 | Yes | Form 4 |
| Kersten Dirk | Aug 20, 2024 | Aug 22, 2024 | S | 8,326 | $47.30 | Sale −$393,820 | 1,036,633 | Yes | Form 4 |
| Kersten Dirk | Aug 19, 2024 | Aug 20, 2024 | S | 30,448 | $45.10 | Sale −$1,373,205 | 1,219,057 | Yes | Form 4 |
| Kersten Dirk | Aug 19, 2024 | Aug 20, 2024 | S | 89,824 | $46.01 | Sale −$4,132,802 | 1,129,233 | Yes | Form 4 |
| Kersten Dirk | Aug 19, 2024 | Aug 20, 2024 | S | 5,760 | $46.59 | Sale −$268,358 | 1,123,473 | Yes | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | Aug 19, 2024 | Aug 20, 2024 | S | 2,340 | $45.01 | Sale −$105,323 | 145,171 | Yes | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | Aug 19, 2024 | Aug 20, 2024 | S | 296 | $46.00 | Sale −$13,616 | 144,875 | Yes | Form 4 |
| High Susanna GattiChief Operating Officer | Aug 19, 2024 | Aug 20, 2024 | S | 2,582 | $45.01 | Sale −$116,216 | 146,210 | Yes | Form 4 |
| High Susanna GattiChief Operating Officer | Aug 19, 2024 | Aug 20, 2024 | S | 328 | $46.00 | Sale −$15,088 | 145,882 | Yes | Form 4 |
| Farwell WildonChief Medical Officer | Aug 19, 2024 | Aug 20, 2024 | S | 2,060 | $45.01 | Sale −$92,721 | 143,483 | Yes | Form 4 |
| Farwell WildonChief Medical Officer | Aug 19, 2024 | Aug 20, 2024 | S | 261 | $46.00 | Sale −$12,006 | 143,222 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Aug 19, 2024 | Aug 20, 2024 | S | 2,400 | $45.01 | Sale −$108,024 | 132,411 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Aug 19, 2024 | Aug 20, 2024 | S | 305 | $46.00 | Sale −$14,030 | 132,106 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Aug 19, 2024 | Aug 20, 2024 | S | 2,442 | $45.01 | Sale −$109,914 | 111,332 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Aug 19, 2024 | Aug 20, 2024 | S | 310 | $46.00 | Sale −$14,260 | 111,022 | Yes | Form 4 |
| Kersten Dirk | Aug 16, 2024 | Aug 20, 2024 | S | 34,485 | $44.52 | Sale −$1,535,272 | 1,337,663 | Yes | Form 4 |
| Kersten Dirk | Aug 16, 2024 | Aug 20, 2024 | S | 85,086 | $45.35 | Sale −$3,858,650 | 1,252,577 | Yes | Form 4 |
| Kersten Dirk | Aug 16, 2024 | Aug 20, 2024 | S | 3,072 | $46.19 | Sale −$141,896 | 1,249,505 | Yes | Form 4 |
| Kersten Dirk | Aug 15, 2024 | Aug 16, 2024 | S | 131,290 | $45.25 | Sale −$5,940,873 | 1,421,749 | Yes | Form 4 |
| Kersten Dirk | Aug 15, 2024 | Aug 16, 2024 | S | 49,601 | $45.67 | Sale −$2,265,278 | 1,372,148 | Yes | Form 4 |
| Kersten Dirk | Aug 14, 2024 | Aug 16, 2024 | S | 100,650 | $43.67 | Sale −$4,395,386 | 1,553,039 | Yes | Form 4 |
| Kersten Dirk | Aug 13, 2024 | Aug 14, 2024 | S | 24,378 | $42.08 | Sale −$1,025,826 | 1,763,296 | Yes | Form 4 |
| Kersten Dirk | Aug 13, 2024 | Aug 14, 2024 | S | 88,179 | $42.78 | Sale −$3,772,298 | 1,675,117 | Yes | Form 4 |
| Kersten Dirk | Aug 13, 2024 | Aug 14, 2024 | S | 21,428 | $43.57 | Sale −$933,618 | 1,653,689 | Yes | Form 4 |
| Kersten Dirk | Aug 12, 2024 | Aug 14, 2024 | S | 26,416 | $42.74 | Sale −$1,129,020 | 1,839,750 | Yes | Form 4 |
| Kersten Dirk | Aug 12, 2024 | Aug 14, 2024 | S | 52,076 | $43.42 | Sale −$2,261,140 | 1,787,674 | Yes | Form 4 |
| Kersten Dirk | Aug 9, 2024 | Aug 14, 20244/A | S | 50,736 | $42.55 | Sale −$2,158,817 | 1,907,594 | Yes | Form 4/A |
| Kersten Dirk | Aug 9, 2024 | Aug 14, 20244/A | S | 40,268 | $43.44 | Sale −$1,749,242 | 1,867,326 | Yes | Form 4/A |
| Kersten Dirk | Aug 9, 2024 | Aug 14, 20244/A | S | 1,160 | $44.04 | Sale −$51,086 | 1,866,166 | Yes | Form 4/A |
| Kersten Dirk | Aug 8, 2024 | Aug 14, 20244/A | S | 6,377 | $40.74 | Sale −$259,799 | 2,043,623 | Yes | Form 4/A |
| Kersten Dirk | Aug 8, 2024 | Aug 14, 20244/A | S | 16,357 | $42.97 | Sale −$702,860 | 2,027,266 | Yes | Form 4/A |
| Kersten Dirk | Aug 8, 2024 | Aug 14, 20244/A | S | 68,936 | $42.87 | Sale −$2,955,286 | 1,958,330 | Yes | Form 4/A |
| High Susanna GattiChief Operating Officer | Jun 24, 2024 | Jul 3, 20244/A | M | 10,213 | $5.54 | $56,580 | 159,005 | Yes | Form 4/A |
| High Susanna GattiChief Operating Officer | Jun 24, 2024 | Jul 3, 20244/A | S | 10,213 | $35.33 | Sale −$360,825 | 148,792 | Yes | Form 4/A |
| High Susanna GattiChief Operating Officer | Jun 24, 2024 | Jul 3, 20244/A | M · derivative | 10,213 | $5.54 | $56,580 | 60,486 | Yes | Form 4/A |
| High Susanna GattiChief Operating Officer | Jun 21, 2024 | Jul 3, 20244/A | M | 29,787 | $5.54 | $165,020 | 178,579 | Yes | Form 4/A |
| High Susanna GattiChief Operating Officer | Jun 21, 2024 | Jul 3, 20244/A | S | 29,787 | $35.01 | Sale −$1,042,843 | 148,792 | Yes | Form 4/A |
| High Susanna GattiChief Operating Officer | Jun 21, 2024 | Jul 3, 20244/A | M · derivative | 29,787 | $5.54 | $165,020 | 70,699 | Yes | Form 4/A |
| High Susanna GattiChief Operating Officer | Jun 12, 2024 | Jun 13, 2024 | M | 40,000 | $5.54 | $221,600 | 188,792 | Yes | Form 4 |
| High Susanna GattiChief Operating Officer | Jun 12, 2024 | Jun 13, 2024 | S | 26,036 | $33.17 | Sale −$863,614 | 162,756 | Yes | Form 4 |
| High Susanna GattiChief Operating Officer | Jun 12, 2024 | Jun 13, 2024 | S | 13,964 | $33.70 | Sale −$470,587 | 148,792 | Yes | Form 4 |
| High Susanna GattiChief Operating Officer | Jun 12, 2024 | Jun 13, 2024 | M · derivative | 40,000 | $5.54 | $221,600 | 100,486 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Jun 11, 2024 | Jun 11, 2024 | S | 1,331 | $31.34 | Sale −$41,714 | 113,774 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Jun 11, 2024 | Jun 11, 2024 | S | 1,823 | $31.34 | Sale −$57,133 | 134,811 | No | Form 4 |
| High Susanna GattiChief Operating Officer | Jun 11, 2024 | Jun 11, 2024 | S | 2,357 | $31.23 | Sale −$73,609 | 151,705 | Yes | Form 4 |
| High Susanna GattiChief Operating Officer | Jun 11, 2024 | Jun 11, 2024 | S | 2,913 | $31.23 | Sale −$90,973 | 148,792 | Yes | Form 4 |
| Farwell WildonChief Medical Officer | Jun 11, 2024 | Jun 11, 2024 | S | 1,628 | $31.27 | Sale −$50,908 | 146,551 | Yes | Form 4 |
| Farwell WildonChief Medical Officer | Jun 11, 2024 | Jun 11, 2024 | S | 1,008 | $31.27 | Sale −$31,520 | 145,543 | Yes | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | Jun 11, 2024 | Jun 11, 2024 | S | 2,136 | $31.34 | Sale −$66,942 | 147,511 | No | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Jun 10, 2024 | Jun 11, 2024 | S | 1,590 | $30.23 | Sale −$48,066 | 115,105 | Yes | Form 4 |
| High Susanna GattiChief Operating Officer | Jun 10, 2024 | Jun 11, 2024 | M | 80,000 | $5.54 | $443,200 | 234,062 | Yes | Form 4 |
| High Susanna GattiChief Operating Officer | Jun 10, 2024 | Jun 11, 2024 | S | 80,000 | $30.24 | Sale −$2,419,200 | 154,062 | Yes | Form 4 |
| High Susanna GattiChief Operating Officer | Jun 10, 2024 | Jun 11, 2024 | M · derivative | 80,000 | $5.54 | $443,200 | 140,486 | Yes | Form 4 |
| Lubner David Charles | May 22, 2024 | May 24, 2024 | A · derivative | 25,133 | $31.53 | $792,443 | 25,133 | No | Form 4 |
| Rhodes Jason P | May 22, 2024 | May 24, 2024 | A · derivative | 25,133 | $31.53 | $792,443 | 25,133 | No | Form 4 |
| Hurwitz Edward | May 22, 2024 | May 24, 2024 | A · derivative | 25,133 | $31.53 | $792,443 | 25,133 | No | Form 4 |
| Incerti Carlo | May 22, 2024 | May 24, 2024 | A · derivative | 25,133 | $31.53 | $792,443 | 25,133 | No | Form 4 |
| Kersten Dirk | May 22, 2024 | May 24, 2024 | A · derivative | 25,133 | $31.53 | $792,443 | 25,133 | No | Form 4 |
| Stehman-Breen Catherine | May 22, 2024 | May 24, 2024 | A · derivative | 25,133 | $31.53 | $792,443 | 25,133 | No | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | May 20, 2024 | May 22, 2024 | M | 30,426 | $1.03 | $31,339 | 180,073 | Yes | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | May 20, 2024 | May 22, 2024 | S | 17,134 | $32.49 | Sale −$556,684 | 162,939 | Yes | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | May 20, 2024 | May 22, 2024 | S | 12,147 | $33.51 | Sale −$407,046 | 150,792 | Yes | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | May 20, 2024 | May 22, 2024 | S | 1,145 | $34.08 | Sale −$39,022 | 149,647 | Yes | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | May 20, 2024 | May 22, 2024 | M · derivative | 30,426 | $1.03 | $31,339 | not reported | Yes | Form 4 |
| McNeill JonathanChief Business Officer | May 16, 2024 | May 17, 2024 | S | 2,279 | $28.20 | Sale −$64,268 | 137,129 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | May 16, 2024 | May 17, 2024 | S | 495 | $28.59 | Sale −$14,152 | 136,634 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | May 16, 2024 | May 17, 2024 | S | 2,126 | $28.20 | Sale −$59,953 | 117,157 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | May 16, 2024 | May 17, 2024 | S | 462 | $28.59 | Sale −$13,209 | 116,695 | Yes | Form 4 |
| High Susanna GattiChief Operating Officer | May 16, 2024 | May 17, 2024 | S | 2,249 | $28.20 | Sale −$63,422 | 154,551 | Yes | Form 4 |
| High Susanna GattiChief Operating Officer | May 16, 2024 | May 17, 2024 | S | 489 | $28.59 | Sale −$13,981 | 154,062 | Yes | Form 4 |
| Farwell WildonChief Medical Officer | May 16, 2024 | May 17, 2024 | S | 1,956 | $28.20 | Sale −$55,159 | 148,604 | Yes | Form 4 |
| Farwell WildonChief Medical Officer | May 16, 2024 | May 17, 2024 | S | 425 | $28.59 | Sale −$12,151 | 148,179 | Yes | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | May 16, 2024 | May 17, 2024 | S | 2,222 | $28.20 | Sale −$62,660 | 150,130 | Yes | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | May 16, 2024 | May 17, 2024 | S | 483 | $28.59 | Sale −$13,809 | 149,647 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Jul 11, 2023 | Apr 4, 2024 | A · derivative | 35,000 | $11.79 | $412,650 | 35,000 | No | Form 4 |
| Cox JohnSee Remarks | Mar 25, 2024 | Mar 27, 2024 | A · derivative | 679,853 | $26.06 | $17,716,969 | 679,853 | No | Form 4 |
| McNeill JonathanChief Business Officer | Mar 11, 2024 | Mar 13, 2024 | M | 17,825 | $5.54 | $98,751 | 159,009 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Mar 11, 2024 | Mar 13, 2024 | S | 17,825 | $25.48 | Sale −$454,181 | 141,184 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Mar 11, 2024 | Mar 13, 2024 | S | 1,776 | $25.71 | Sale −$45,661 | 139,408 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Mar 11, 2024 | Mar 13, 2024 | M · derivative | 17,825 | $5.54 | $98,751 | not reported | Yes | Form 4 |
| High Susanna GattiChief Operating Officer | Mar 11, 2024 | Mar 13, 2024 | S | 2,292 | $25.70 | Sale −$58,904 | 156,800 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Mar 8, 2024 | Mar 13, 2024 | M | 86,159 | $5.54 | $477,321 | 227,343 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Mar 8, 2024 | Mar 13, 2024 | M | 3,841 | $5.54 | $21,279 | 231,184 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Mar 8, 2024 | Mar 13, 2024 | S | 34,663 | $25.46 | Sale −$882,520 | 196,521 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Mar 8, 2024 | Mar 13, 2024 | S | 54,648 | $26.72 | Sale −$1,460,195 | 141,873 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Mar 8, 2024 | Mar 13, 2024 | S | 689 | $27.31 | Sale −$18,817 | 141,184 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Mar 8, 2024 | Mar 13, 2024 | M · derivative | 86,159 | $5.54 | $477,321 | 12,309 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Mar 8, 2024 | Mar 13, 2024 | M · derivative | 3,841 | $5.54 | $21,279 | not reported | Yes | Form 4 |
| High Susanna GattiChief Operating Officer | Mar 8, 2024 | Mar 13, 2024 | S | 26,908 | $26.66 | Sale −$717,367 | 159,383 | Yes | Form 4 |
| High Susanna GattiChief Operating Officer | Mar 8, 2024 | Mar 13, 2024 | S | 291 | $27.41 | Sale −$7,976 | 159,092 | Yes | Form 4 |
| Farwell WildonChief Medical Officer | Mar 12, 2024 | Mar 12, 2024 | S | 1,030 | $25.58 | Sale −$26,347 | 150,560 | Yes | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | Mar 11, 2024 | Mar 12, 2024 | S | 2,081 | $25.70 | Sale −$53,482 | 152,352 | Yes | Form 4 |
| Brumm Joshua TCEO & President | Mar 11, 2024 | Mar 12, 2024 | M | 50,000 | $5.54 | $277,000 | 604,385 | Yes | Form 4 |
| Brumm Joshua TCEO & President | Mar 11, 2024 | Mar 12, 2024 | S | 40,072 | $25.42 | Sale −$1,018,630 | 564,313 | Yes | Form 4 |
| Brumm Joshua TCEO & President | Mar 11, 2024 | Mar 12, 2024 | S | 9,928 | $26.10 | Sale −$259,121 | 554,385 | Yes | Form 4 |
| Brumm Joshua TCEO & President | Mar 11, 2024 | Mar 12, 2024 | S | 7,769 | $26.12 | Sale −$202,926 | 546,616 | Yes | Form 4 |
| Brumm Joshua TCEO & President | Mar 11, 2024 | Mar 12, 2024 | S | 8,618 | $25.93 | Sale −$223,465 | 537,998 | Yes | Form 4 |
| Brumm Joshua TCEO & President | Mar 11, 2024 | Mar 12, 2024 | M · derivative | 50,000 | $5.54 | $277,000 | 83,269 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Mar 11, 2024 | Mar 12, 2024 | S | 1,082 | $25.70 | Sale −$27,807 | 120,873 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Mar 11, 2024 | Mar 12, 2024 | S | 1,590 | $24.99 | Sale −$39,734 | 119,283 | Yes | Form 4 |
| Farwell WildonChief Medical Officer | Mar 11, 2024 | Mar 12, 2024 | S | 1,585 | $25.70 | Sale −$40,735 | 151,590 | Yes | Form 4 |
| Brumm Joshua TCEO & President | Mar 8, 2024 | Mar 12, 2024 | M | 153,931 | $5.54 | $852,778 | 708,316 | Yes | Form 4 |
| Brumm Joshua TCEO & President | Mar 8, 2024 | Mar 12, 2024 | M | 209,412 | $5.54 | $1,160,142 | 917,728 | Yes | Form 4 |
| Brumm Joshua TCEO & President | Mar 8, 2024 | Mar 12, 2024 | S | 202,238 | $25.30 | Sale −$5,116,621 | 715,490 | Yes | Form 4 |
| Brumm Joshua TCEO & President | Mar 8, 2024 | Mar 12, 2024 | S | 160,670 | $26.72 | Sale −$4,293,102 | 554,820 | Yes | Form 4 |
| Brumm Joshua TCEO & President | Mar 8, 2024 | Mar 12, 2024 | S | 435 | $27.38 | Sale −$11,910 | 554,385 | Yes | Form 4 |
| Brumm Joshua TCEO & President | Mar 8, 2024 | Mar 12, 2024 | M · derivative | 153,931 | $5.54 | $852,778 | not reported | Yes | Form 4 |
| Brumm Joshua TCEO & President | Mar 8, 2024 | Mar 12, 2024 | M · derivative | 209,412 | $5.54 | $1,160,142 | 133,269 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Mar 8, 2024 | Mar 12, 2024 | M | 68,919 | $5.54 | $381,811 | 190,874 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Mar 8, 2024 | Mar 12, 2024 | M | 17,333 | $5.54 | $96,025 | 208,207 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Mar 8, 2024 | Mar 12, 2024 | S | 30,755 | $25.31 | Sale −$778,409 | 177,452 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Mar 8, 2024 | Mar 12, 2024 | S | 55,208 | $26.72 | Sale −$1,475,158 | 122,244 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Mar 8, 2024 | Mar 12, 2024 | S | 289 | $27.33 | Sale −$7,898 | 121,955 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Mar 8, 2024 | Mar 12, 2024 | M · derivative | 68,919 | $5.54 | $381,811 | 9,855 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Mar 8, 2024 | Mar 12, 2024 | M · derivative | 17,333 | $5.54 | $96,025 | not reported | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Mar 7, 2024 | Mar 11, 2024 | S | 2,273 | $25.85 | Sale −$58,757 | 121,955 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Mar 7, 2024 | Mar 11, 2024 | S | 2,434 | $25.85 | Sale −$62,919 | 141,184 | Yes | Form 4 |
| Farwell WildonChief Medical Officer | Mar 7, 2024 | Mar 11, 2024 | S | 8,364 | $25.80 | Sale −$215,791 | 154,732 | Yes | Form 4 |
| Farwell WildonChief Medical Officer | Mar 7, 2024 | Mar 11, 2024 | S | 1,557 | $26.20 | Sale −$40,793 | 153,175 | Yes | Form 4 |
| High Susanna GattiChief Operating Officer | Mar 7, 2024 | Mar 11, 2024 | S | 1,591 | $25.85 | Sale −$41,127 | 186,291 | Yes | Form 4 |
| Beskrovnaya OxanaChief Scientific Officer | Mar 7, 2024 | Mar 11, 2024 | S | 2,373 | $25.85 | Sale −$61,342 | 154,433 | Yes | Form 4 |
| Brumm Joshua TCEO & President | Mar 7, 2024 | Mar 11, 2024 | S | 9,086 | $25.85 | Sale −$234,873 | 554,385 | Yes | Form 4 |
| Atlas Venture Associates Opportunity II, LP | Mar 1, 2024 | Mar 5, 2024 | S | 29,435 | $30.05 | Sale −$884,522 | 1,458,691 | Yes | Form 4 |
| Atlas Venture Associates Opportunity II, LP | Mar 1, 2024 | Mar 5, 2024 | S | 17,099 | $30.05 | Sale −$513,825 | 847,388 | Yes | Form 4 |
| Rhodes Jason P | Mar 1, 2024 | Mar 5, 2024 | S | 29,435 | $30.05 | Sale −$884,522 | 1,458,691 | Yes | Form 4 |
| Rhodes Jason P | Mar 1, 2024 | Mar 5, 2024 | S | 17,099 | $30.05 | Sale −$513,825 | 847,388 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Mar 1, 2024 | Mar 1, 2024 | M | 9,311 | $1.03 | $9,590 | 133,539 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Mar 1, 2024 | Mar 1, 2024 | S | 8,747 | $28.22 | Sale −$246,840 | 124,792 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Mar 1, 2024 | Mar 1, 2024 | S | 564 | $28.65 | Sale −$16,159 | 124,228 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Mar 1, 2024 | Mar 1, 2024 | M · derivative | 9,311 | $1.03 | $9,590 | not reported | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Mar 1, 2024 | Mar 1, 2024 | M | 24,260 | $0.73 | $17,710 | 167,878 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Mar 1, 2024 | Mar 1, 2024 | S | 14,103 | $28.25 | Sale −$398,410 | 153,775 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Mar 1, 2024 | Mar 1, 2024 | S | 8,715 | $29.06 | Sale −$253,258 | 145,060 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Mar 1, 2024 | Mar 1, 2024 | S | 1,442 | $29.70 | Sale −$42,827 | 143,618 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Mar 1, 2024 | Mar 1, 2024 | M · derivative | 24,260 | $0.73 | $17,710 | not reported | Yes | Form 4 |
| Brumm Joshua TCEO & President | Mar 1, 2024 | Mar 1, 2024 | M | 94,480 | $5.54 | $523,419 | 657,951 | Yes | Form 4 |
| Brumm Joshua TCEO & President | Mar 1, 2024 | Mar 1, 2024 | S | 18,976 | $28.25 | Sale −$536,072 | 638,975 | Yes | Form 4 |
| Brumm Joshua TCEO & President | Mar 1, 2024 | Mar 1, 2024 | S | 74,090 | $29.23 | Sale −$2,165,651 | 564,885 | Yes | Form 4 |
| Brumm Joshua TCEO & President | Mar 1, 2024 | Mar 1, 2024 | S | 1,414 | $29.70 | Sale −$41,996 | 563,471 | Yes | Form 4 |
| Brumm Joshua TCEO & President | Mar 1, 2024 | Mar 1, 2024 | M · derivative | 57,843 | $5.54 | $320,450 | 44,500 | Yes | Form 4 |
| Brumm Joshua TCEO & President | Mar 1, 2024 | Mar 1, 2024 | M · derivative | 36,637 | $5.54 | $202,969 | 342,681 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Feb 29, 2024 | Mar 1, 2024 | M | 3,429 | $1.03 | $3,532 | 127,657 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Feb 29, 2024 | Mar 1, 2024 | S | 3,429 | $27.50 | Sale −$94,298 | 124,228 | Yes | Form 4 |
| Scalzo Richard WilliamSVP, Head of Finance & Admin. | Feb 29, 2024 | Mar 1, 2024 | M · derivative | 3,429 | $1.03 | $3,532 | 9,311 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Feb 29, 2024 | Mar 1, 2024 | M | 4,268 | $0.73 | $3,116 | 147,886 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Feb 29, 2024 | Mar 1, 2024 | S | 4,268 | $27.50 | Sale −$117,370 | 143,618 | Yes | Form 4 |
| McNeill JonathanChief Business Officer | Feb 29, 2024 | Mar 1, 2024 | M · derivative | 4,268 | $0.73 | $3,116 | 24,260 | Yes | Form 4 |
| Brumm Joshua TCEO & President | Feb 29, 2024 | Mar 1, 2024 | M | 5,520 | $5.54 | $30,581 | 568,991 | Yes | Form 4 |
| Brumm Joshua TCEO & President | Feb 29, 2024 | Mar 1, 2024 | S | 5,520 | $27.50 | Sale −$151,800 | 563,471 | Yes | Form 4 |
| Brumm Joshua TCEO & President | Feb 29, 2024 | Mar 1, 2024 | M · derivative | 5,520 | $5.54 | $30,581 | 102,343 | Yes | Form 4 |
| Farwell WildonChief Medical Officer | Feb 28, 2024 | Feb 28, 2024 | S | 407 | $25.00 | Sale −$10,175 | 163,096 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 28, 2024 | Feb 28, 2024 | S | 152,244 | $24.83 | Sale −$3,780,219 | 5,700,521 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 28, 2024 | Feb 28, 2024 | S | 2,430 | $25.25 | Sale −$61,358 | 5,698,091 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 28, 2024 | Feb 28, 2024 | S | 22,567 | $24.83 | Sale −$560,339 | 1,488,486 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 28, 2024 | Feb 28, 2024 | S | 360 | $25.25 | Sale −$9,090 | 1,488,126 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 28, 2024 | Feb 28, 2024 | S | 13,109 | $24.83 | Sale −$325,496 | 864,697 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 28, 2024 | Feb 28, 2024 | S | 210 | $25.25 | Sale −$5,303 | 864,487 | Yes | Form 4 |
| Rhodes Jason P | Feb 28, 2024 | Feb 28, 2024 | S | 152,244 | $24.83 | Sale −$3,780,219 | 5,700,521 | Yes | Form 4 |
| Rhodes Jason P | Feb 28, 2024 | Feb 28, 2024 | S | 2,430 | $25.25 | Sale −$61,358 | 5,698,091 | Yes | Form 4 |
| Rhodes Jason P | Feb 28, 2024 | Feb 28, 2024 | S | 22,567 | $24.83 | Sale −$560,339 | 1,488,486 | Yes | Form 4 |
| Rhodes Jason P | Feb 28, 2024 | Feb 28, 2024 | S | 360 | $25.25 | Sale −$9,090 | 1,488,126 | Yes | Form 4 |
| Rhodes Jason P | Feb 28, 2024 | Feb 28, 2024 | S | 13,109 | $24.83 | Sale −$325,496 | 864,697 | Yes | Form 4 |
| Rhodes Jason P | Feb 28, 2024 | Feb 28, 2024 | S | 210 | $25.25 | Sale −$5,303 | 864,487 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 27, 2024 | Feb 28, 2024 | S | 272,923 | $24.38 | Sale −$6,653,863 | 5,878,544 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 27, 2024 | Feb 28, 2024 | S | 25,779 | $24.68 | Sale −$636,226 | 5,852,765 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 27, 2024 | Feb 28, 2024 | S | 40,455 | $24.38 | Sale −$986,293 | 1,514,874 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 27, 2024 | Feb 28, 2024 | S | 3,821 | $24.68 | Sale −$94,302 | 1,511,053 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 27, 2024 | Feb 28, 2024 | S | 23,505 | $24.38 | Sale −$573,052 | 880,022 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 27, 2024 | Feb 28, 2024 | S | 2,216 | $24.68 | Sale −$54,691 | 877,806 | Yes | Form 4 |
| Rhodes Jason P | Feb 27, 2024 | Feb 28, 2024 | S | 272,923 | $24.38 | Sale −$6,653,863 | 5,878,544 | Yes | Form 4 |
| Rhodes Jason P | Feb 27, 2024 | Feb 28, 2024 | S | 25,779 | $24.68 | Sale −$636,226 | 5,852,765 | Yes | Form 4 |
| Rhodes Jason P | Feb 27, 2024 | Feb 28, 2024 | S | 40,455 | $24.38 | Sale −$986,293 | 1,514,874 | Yes | Form 4 |
| Rhodes Jason P | Feb 27, 2024 | Feb 28, 2024 | S | 3,821 | $24.68 | Sale −$94,302 | 1,511,053 | Yes | Form 4 |
| Rhodes Jason P | Feb 27, 2024 | Feb 28, 2024 | S | 23,505 | $24.38 | Sale −$573,052 | 880,022 | Yes | Form 4 |
| Rhodes Jason P | Feb 27, 2024 | Feb 28, 2024 | S | 2,216 | $24.68 | Sale −$54,691 | 877,806 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 26, 2024 | Feb 28, 2024 | S | 136,312 | $23.59 | Sale −$3,215,600 | 6,216,250 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 26, 2024 | Feb 28, 2024 | S | 64,783 | $23.98 | Sale −$1,553,496 | 6,151,467 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 26, 2024 | Feb 28, 2024 | S | 20,205 | $23.59 | Sale −$476,636 | 1,564,932 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 26, 2024 | Feb 28, 2024 | S | 9,603 | $23.98 | Sale −$230,280 | 1,555,329 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 26, 2024 | Feb 28, 2024 | S | 11,736 | $23.59 | Sale −$276,852 | 909,107 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 26, 2024 | Feb 28, 2024 | S | 5,580 | $23.98 | Sale −$133,808 | 903,527 | Yes | Form 4 |
| Rhodes Jason P | Feb 26, 2024 | Feb 28, 2024 | S | 136,312 | $23.59 | Sale −$3,215,600 | 6,216,250 | Yes | Form 4 |
| Rhodes Jason P | Feb 26, 2024 | Feb 28, 2024 | S | 64,783 | $23.98 | Sale −$1,553,496 | 6,151,467 | Yes | Form 4 |
| Rhodes Jason P | Feb 26, 2024 | Feb 28, 2024 | S | 20,205 | $23.59 | Sale −$476,636 | 1,564,932 | Yes | Form 4 |
| Rhodes Jason P | Feb 26, 2024 | Feb 28, 2024 | S | 9,603 | $23.98 | Sale −$230,280 | 1,555,329 | Yes | Form 4 |
| Rhodes Jason P | Feb 26, 2024 | Feb 28, 2024 | S | 11,736 | $23.59 | Sale −$276,852 | 909,107 | Yes | Form 4 |
| Rhodes Jason P | Feb 26, 2024 | Feb 28, 2024 | S | 5,580 | $23.98 | Sale −$133,808 | 903,527 | Yes | Form 4 |
| Atlas Venture Associates XI, LLC | Feb 23, 2024 | Feb 23, 2024 | S | 159,542 | $22.70 | Sale −$3,621,603 | 6,352,562 | Yes | Form 4 |
| Atlas Venture Associates XI, LLC | Feb 23, 2024 | Feb 23, 2024 | S | 23,648 | $22.70 | Sale −$536,810 | 1,585,137 | Yes | Form 4 |
| Atlas Venture Associates XI, LLC | Feb 23, 2024 | Feb 23, 2024 | S | 13,738 | $22.70 | Sale −$311,853 | 920,843 | Yes | Form 4 |
| Rhodes Jason P | Feb 23, 2024 | Feb 23, 2024 | S | 159,542 | $22.70 | Sale −$3,621,603 | 6,352,562 | Yes | Form 4 |
| Rhodes Jason P | Feb 23, 2024 | Feb 23, 2024 | S | 23,648 | $22.70 | Sale −$536,810 | 1,585,137 | Yes | Form 4 |
| Rhodes Jason P | Feb 23, 2024 | Feb 23, 2024 | S | 13,738 | $22.70 | Sale −$311,853 | 920,843 | Yes | Form 4 |
| Atlas Venture Associates XI, LLC | Feb 22, 2024 | Feb 23, 2024 | S | 119,360 | $22.66 | Sale −$2,704,698 | 6,512,104 | Yes | Form 4 |
| Rhodes Jason P | Feb 22, 2024 | Feb 23, 2024 | S | 119,360 | $22.66 | Sale −$2,704,698 | 6,512,104 | Yes | Form 4 |
| Atlas Venture Associates XI, LLC | Feb 21, 2024 | Feb 23, 2024 | S | 149,337 | $22.44 | Sale −$3,351,122 | 6,666,628 | Yes | Form 4 |
| Atlas Venture Associates XI, LLC | Feb 21, 2024 | Feb 23, 2024 | S | 35,164 | $23.14 | Sale −$813,695 | 6,631,464 | Yes | Form 4 |
| Rhodes Jason P | Feb 21, 2024 | Feb 23, 2024 | S | 149,337 | $22.44 | Sale −$3,351,122 | 6,666,628 | Yes | Form 4 |
| Rhodes Jason P | Feb 21, 2024 | Feb 23, 2024 | S | 35,164 | $23.14 | Sale −$813,695 | 6,631,464 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 20, 2024 | Feb 20, 2024 | S | 166,029 | $22.71 | Sale −$3,770,519 | 6,819,475 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 20, 2024 | Feb 20, 2024 | S | 3,510 | $23.40 | Sale −$82,134 | 6,815,965 | Yes | Form 4 |
| Rhodes Jason P | Feb 20, 2024 | Feb 20, 2024 | S | 166,029 | $22.71 | Sale −$3,770,519 | 6,819,475 | Yes | Form 4 |
| Rhodes Jason P | Feb 20, 2024 | Feb 20, 2024 | S | 3,510 | $23.40 | Sale −$82,134 | 6,815,965 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 16, 2024 | Feb 20, 2024 | S | 162,707 | $23.14 | Sale −$3,765,040 | 6,985,504 | Yes | Form 4 |
| Rhodes Jason P | Feb 16, 2024 | Feb 20, 2024 | S | 162,707 | $23.14 | Sale −$3,765,040 | 6,985,504 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 15, 2024 | Feb 20, 2024 | S | 175,793 | $23.88 | Sale −$4,197,937 | 7,150,324 | Yes | Form 4 |
| Atlas Venture Associates XI, L.P. | Feb 15, 2024 | Feb 20, 2024 | S | 2,113 | $24.45 | Sale −$51,663 | 7,148,211 | Yes | Form 4 |
| Rhodes Jason P | Feb 15, 2024 | Feb 20, 2024 | S | 175,793 | $23.88 | Sale −$4,197,937 | 7,150,324 | Yes | Form 4 |
| Rhodes Jason P | Feb 15, 2024 | Feb 20, 2024 | S | 2,113 | $24.45 | Sale −$51,663 | 7,148,211 | Yes | Form 4 |
| Farwell WildonChief Medical Officer | Feb 12, 2024 | Feb 14, 2024 | S | 5,493 | $25.07 | Sale −$137,710 | 163,503 | Yes | Form 4 |