HIMSHims & Hers Health, Inc.
- Market cap
- $6.47B
- as of 2026-10-23
- Latest close
- $27.71
- as of 2026-10-23
- Sector
- Healthcare
- as of 2026-10-24
- Industry
- Drug Manufacturers - Specialty & Generic
- as of 2026-10-24
Cluster
No cluster in the last 90 days under the default rule (14d · ≥2 insiders · all roles).
Form 4 historysince 2023-10-06
Showing the latest 500 of 1763 transactions.
| Insider | Traded | Filed | Type | Shares | Price | Value | Owned after | 10b5-1 plan | Filing |
|---|---|---|---|---|---|---|---|---|---|
| Boughton SoleilChief Legal Officer | Oct 14 | Oct 15 | S | 3,461 | $29.06 | Sale −$100,577 | 297,348 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Oct 1 | Oct 2 | S | 2,000 | $29.70 | Sale −$59,400 | 234,527 | Yes | Form 4 |
| Boughton SoleilChief Legal Officer | Sep 30 | Oct 2 | S | 3,461 | $29.17 | Sale −$100,957 | 300,809 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Sep 22 | Sep 23 | M | 14,000 | $5.01 | $70,140 | 265,804 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Sep 22 | Sep 23 | S | 29,277 | $29.95 | Sale −$876,846 | 236,527 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Sep 22 | Sep 23 | M · derivative | 14,000 | $5.01 | $70,140 | 66,872 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Sep 17 | Sep 18 | S | 12,313 | $28.82 | Sale −$354,861 | 251,804 | Yes | Form 4 |
| Boughton SoleilChief Legal Officer | Sep 16 | Sep 17 | S | 6,236 | $27.86 | Sale −$173,735 | 304,270 | Yes | Form 4 |
| Chi MichaelChief Operating Officer | Sep 15 | Sep 17 | S | 14,027 | $28.39 | Sale −$398,227 | 456,660 | Yes | Form 4 |
| Elshenawy MohamedCTO | Sep 15 | Sep 17 | S | 7,954 | $28.39 | Sale −$225,814 | 185,556 | Yes | Form 4 |
| Boughton SoleilChief Legal Officer | Sep 2 | Sep 3 | S | 3,458 | $28.33 | Sale −$97,965 | 310,506 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Aug 27 | Aug 27 | J | 977,566 | $0.00 | $0 | 103,406 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Aug 25 | Aug 27 | G | 463,289 | $0.00 | $0 | not reported | No | Form 4 |
| Boughton SoleilChief Legal Officer | Aug 19 | Aug 20 | S | 25,111 | $27.55 | Sale −$691,808 | 313,964 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Aug 19 | Aug 20 | M | 4,938 | $5.01 | $24,739 | 269,055 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Aug 19 | Aug 20 | S | 4,938 | $29.99 | Sale −$148,091 | 264,117 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Aug 19 | Aug 20 | M · derivative | 4,938 | $5.01 | $24,739 | 80,872 | Yes | Form 4 |
| Autor Deborah M.Chief Policy Officer | Aug 18 | Aug 20 | S | 16,773 | $27.85 | Sale −$467,128 | 48,961 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Aug 17 | Aug 18 | M | 9,388 | $5.01 | $47,034 | 273,505 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Aug 17 | Aug 18 | S | 9,388 | $27.89 | Sale −$261,831 | 264,117 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Aug 17 | Aug 18 | M · derivative | 9,388 | $5.01 | $47,034 | 85,810 | Yes | Form 4 |
| Payne Christopher D | Aug 14 | Aug 18 | M | 545 | not reported | not reported | 34,863 | No | Form 4 |
| Payne Christopher D | Aug 14 | Aug 18 | M · derivative | 545 | $0.00 | $0 | not reported | No | Form 4 |
| Becklund IrenePAO | Aug 14 | Aug 18 | M | 13,685 | not reported | not reported | 20,475 | No | Form 4 |
| Becklund IrenePAO | Aug 14 | Aug 18 | F | 6,490 | $28.15 | $182,694 | 13,985 | No | Form 4 |
| Becklund IrenePAO | Aug 14 | Aug 18 | M · derivative | 4,066 | $0.00 | $0 | 8,133 | No | Form 4 |
| Becklund IrenePAO | Aug 14 | Aug 18 | M · derivative | 4,345 | $0.00 | $0 | 26,070 | No | Form 4 |
| Becklund IrenePAO | Aug 14 | Aug 18 | M · derivative | 1,394 | $0.00 | $0 | 13,928 | No | Form 4 |
| Becklund IrenePAO | Aug 14 | Aug 18 | M · derivative | 3,880 | $0.00 | $0 | 54,317 | No | Form 4 |
| Elshenawy MohamedCTO | Aug 14 | Aug 18 | M | 188,285 | not reported | not reported | 289,308 | No | Form 4 |
| Elshenawy MohamedCTO | Aug 14 | Aug 18 | F | 95,798 | $28.15 | $2,696,714 | 193,510 | No | Form 4 |
| Elshenawy MohamedCTO | Aug 14 | Aug 18 | M · derivative | 64,771 | $0.00 | $0 | 712,484 | No | Form 4 |
| Elshenawy MohamedCTO | Aug 14 | Aug 18 | M · derivative | 23,514 | $0.00 | $0 | 329,195 | No | Form 4 |
| Elshenawy MohamedCTO | Aug 14 | Aug 18 | M · derivative | 100,000 | $0.00 | $0 | 1,100,000 | No | Form 4 |
| Wells David B | Aug 14 | Aug 18 | M | 778 | not reported | not reported | 229,808 | No | Form 4 |
| Wells David B | Aug 14 | Aug 18 | M · derivative | 778 | $0.00 | $0 | not reported | No | Form 4 |
| Autor Deborah M.Chief Policy Officer | Aug 14 | Aug 18 | M | 32,920 | not reported | not reported | 81,881 | No | Form 4 |
| Autor Deborah M.Chief Policy Officer | Aug 14 | Aug 18 | F | 16,147 | $28.15 | $454,538 | 65,734 | No | Form 4 |
| Autor Deborah M.Chief Policy Officer | Aug 14 | Aug 18 | M · derivative | 32,920 | $0.00 | $0 | 427,953 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Aug 14 | Aug 18 | M | 71,616 | not reported | not reported | 300,554 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Aug 14 | Aug 18 | F | 36,437 | $28.15 | $1,025,702 | 264,117 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Aug 14 | Aug 18 | M · derivative | 18,335 | $0.00 | $0 | 36,669 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Aug 14 | Aug 18 | M · derivative | 22,988 | $0.00 | $0 | 137,929 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Aug 14 | Aug 18 | M · derivative | 11,482 | $0.00 | $0 | 114,825 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Aug 14 | Aug 18 | M · derivative | 18,811 | $0.00 | $0 | 263,356 | Yes | Form 4 |
| Chi MichaelChief Operating Officer | Aug 14 | Aug 18 | M | 86,265 | not reported | not reported | 518,389 | No | Form 4 |
| Chi MichaelChief Operating Officer | Aug 14 | Aug 18 | F | 47,702 | $28.15 | $1,342,811 | 470,687 | No | Form 4 |
| Chi MichaelChief Operating Officer | Aug 14 | Aug 18 | M · derivative | 16,496 | $0.00 | $0 | not reported | No | Form 4 |
| Chi MichaelChief Operating Officer | Aug 14 | Aug 18 | M · derivative | 16,297 | $0.00 | $0 | 32,595 | No | Form 4 |
| Chi MichaelChief Operating Officer | Aug 14 | Aug 18 | M · derivative | 19,358 | $0.00 | $0 | 116,151 | No | Form 4 |
| Chi MichaelChief Operating Officer | Aug 14 | Aug 18 | M · derivative | 10,600 | $0.00 | $0 | 105,992 | No | Form 4 |
| Chi MichaelChief Operating Officer | Aug 14 | Aug 18 | M · derivative | 23,514 | $0.00 | $0 | 329,194 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Aug 14 | Aug 18 | M | 154,993 | not reported | not reported | 1,112,036 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Aug 14 | Aug 18 | F | 78,859 | $28.15 | $2,219,881 | 1,033,177 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Aug 14 | Aug 18 | M · derivative | 35,447 | $0.00 | $0 | 70,893 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Aug 14 | Aug 18 | M · derivative | 74,530 | $0.00 | $0 | 447,179 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Aug 14 | Aug 18 | M · derivative | 19,151 | $0.00 | $0 | 191,504 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Aug 14 | Aug 18 | M · derivative | 25,865 | $0.00 | $0 | 362,114 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Aug 14 | Aug 18 | M | 260 | not reported | not reported | 182,121 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Aug 14 | Aug 18 | M | 25,927 | not reported | not reported | 208,048 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Aug 14 | Aug 18 | F | 10,201 | $28.15 | $287,158 | 197,847 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Aug 14 | Aug 18 | M · derivative | 260 | $0.00 | $0 | not reported | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Aug 14 | Aug 18 | M · derivative | 8,149 | $0.00 | $0 | 8,149 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Aug 14 | Aug 18 | M · derivative | 4,839 | $0.00 | $0 | 29,038 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Aug 14 | Aug 18 | M · derivative | 3,533 | $0.00 | $0 | 35,331 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Aug 14 | Aug 18 | M · derivative | 9,406 | $0.00 | $0 | 131,678 | No | Form 4 |
| Schultz Kare | Aug 14 | Aug 18 | M | 6,623 | not reported | not reported | 26,020 | No | Form 4 |
| Schultz Kare | Aug 14 | Aug 18 | M · derivative | 6,623 | $0.00 | $0 | 6,624 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Aug 14 | Aug 18 | M | 42,261 | not reported | not reported | 360,575 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Aug 14 | Aug 18 | F | 21,500 | $28.15 | $605,225 | 339,075 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Aug 14 | Aug 18 | M · derivative | 12,223 | $0.00 | $0 | 24,446 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Aug 14 | Aug 18 | M · derivative | 12,099 | $0.00 | $0 | 72,594 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Aug 14 | Aug 18 | M · derivative | 6,182 | $0.00 | $0 | 61,829 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Aug 14 | Aug 18 | M · derivative | 11,757 | $0.00 | $0 | 164,598 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Jun 18 | Aug 18 | S | 55,383 | $35.09 | Sale −$1,943,389 | 228,938 | Yes | Form 4 |
| Amoo-Gottfried Kofi Owusu | Aug 12 | Aug 14 | A · derivative | 13,157 | $0.00 | $0 | 13,157 | No | Form 4 |
| Amoo-Gottfried Kofi Owusu | Aug 12 | Aug 14 | A · derivative | 8,223 | $0.00 | $0 | 8,223 | No | Form 4 |
| Wells David B | Aug 12 | Aug 14 | A · derivative | 8,223 | $0.00 | $0 | 8,223 | No | Form 4 |
| Wells David B | Aug 12 | Aug 14 | A · derivative | 778 | $0.00 | $0 | 778 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Aug 12 | Aug 14 | A · derivative | 260 | $0.00 | $0 | 260 | No | Form 4 |
| Autor Deborah M.Chief Policy Officer | Aug 12 | Aug 14 | A · derivative | 8,223 | $0.00 | $0 | 8,223 | No | Form 4 |
| Cosgrove Delos M. | Aug 12 | Aug 14 | A · derivative | 8,223 | $0.00 | $0 | 8,223 | No | Form 4 |
| Manuel Anja | Aug 12 | Aug 14 | A · derivative | 8,223 | $0.00 | $0 | 8,223 | No | Form 4 |
| Perez Garcia Andrea G | Aug 12 | Aug 14 | A · derivative | 8,223 | $0.00 | $0 | 8,223 | No | Form 4 |
| Payne Christopher D | Aug 12 | Aug 14 | A · derivative | 8,223 | $0.00 | $0 | 8,223 | No | Form 4 |
| Payne Christopher D | Aug 12 | Aug 14 | A · derivative | 545 | $0.00 | $0 | 545 | No | Form 4 |
| Schultz Kare | Aug 12 | Aug 14 | A · derivative | 8,223 | $0.00 | $0 | 8,223 | No | Form 4 |
| Elshenawy MohamedCTO | Aug 12 | Aug 14 | A · derivative | 1,200,000 | $0.00 | $0 | 1,200,000 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Jul 17 | Jul 20 | M | 7,163 | $5.01 | $35,887 | 291,484 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Jul 17 | Jul 20 | S | 7,163 | $31.99 | Sale −$229,144 | 284,321 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Jul 17 | Jul 20 | M · derivative | 7,163 | $5.01 | $35,887 | 95,198 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Jul 6 | Jul 7 | M | 7,163 | $5.01 | $35,887 | 291,484 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Jul 6 | Jul 7 | S | 7,163 | $36.49 | Sale −$261,378 | 284,321 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Jul 6 | Jul 7 | M · derivative | 7,163 | $5.01 | $35,887 | 102,361 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Jun 22 | Jun 23 | M | 6,376 | $5.01 | $31,944 | 302,518 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Jun 22 | Jun 23 | S | 18,197 | $34.03 | Sale −$619,244 | 284,321 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Jun 22 | Jun 23 | M · derivative | 6,376 | $5.01 | $31,944 | 109,524 | Yes | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Jun 18 | Jun 23 | S | 23,726 | $35.00 | Sale −$830,410 | 181,861 | Yes | Form 4 |
| Elshenawy MohamedCTO | Jun 17 | Jun 17 | S | 30,040 | $31.50 | Sale −$946,260 | 101,023 | Yes | Form 4 |
| Becklund IrenePAO | Jun 17 | Jun 17 | S | 4,490 | $31.50 | Sale −$141,435 | 6,790 | Yes | Form 4 |
| Chi MichaelChief Operating Officer | Jun 17 | Jun 17 | S | 14,027 | $31.50 | Sale −$441,851 | 432,124 | Yes | Form 4 |
| Becklund IrenePAO | Jun 16 | Jun 17 | S | 7,573 | $30.25 | Sale −$229,083 | 11,280 | Yes | Form 4 |
| Elshenawy MohamedCTO | Jun 15 | Jun 17 | M | 282,597 | not reported | not reported | 282,597 | Yes | Form 4 |
| Elshenawy MohamedCTO | Jun 15 | Jun 17 | F | 151,534 | $30.17 | $4,571,781 | 131,063 | Yes | Form 4 |
| Elshenawy MohamedCTO | Jun 15 | Jun 17 | M · derivative | 259,084 | $0.00 | $0 | 777,255 | Yes | Form 4 |
| Elshenawy MohamedCTO | Jun 15 | Jun 17 | M · derivative | 23,513 | $0.00 | $0 | 352,709 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Jun 15 | Jun 17 | M | 154,991 | not reported | not reported | 1,042,675 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Jun 15 | Jun 17 | F | 85,632 | $30.17 | $2,583,517 | 957,043 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Jun 15 | Jun 17 | M · derivative | 35,446 | $0.00 | $0 | 106,340 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Jun 15 | Jun 17 | M · derivative | 74,530 | $0.00 | $0 | 521,709 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Jun 15 | Jun 17 | M · derivative | 19,150 | $0.00 | $0 | 210,655 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Jun 15 | Jun 17 | M · derivative | 25,865 | $0.00 | $0 | 387,979 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Jun 15 | Jun 17 | M | 42,261 | not reported | not reported | 341,629 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Jun 15 | Jun 17 | F | 23,315 | $30.17 | $703,414 | 318,314 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Jun 15 | Jun 17 | M · derivative | 12,223 | $0.00 | $0 | 36,669 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Jun 15 | Jun 17 | M · derivative | 12,099 | $0.00 | $0 | 84,693 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Jun 15 | Jun 17 | M · derivative | 6,183 | $0.00 | $0 | 68,011 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Jun 15 | Jun 17 | M · derivative | 11,756 | $0.00 | $0 | 176,355 | No | Form 4 |
| Becklund IrenePAO | Jun 15 | Jun 17 | M | 15,971 | not reported | not reported | 24,723 | Yes | Form 4 |
| Becklund IrenePAO | Jun 15 | Jun 17 | F | 5,870 | $30.17 | $177,098 | 18,853 | Yes | Form 4 |
| Becklund IrenePAO | Jun 15 | Jun 17 | M · derivative | 2,291 | $0.00 | $0 | not reported | Yes | Form 4 |
| Becklund IrenePAO | Jun 15 | Jun 17 | M · derivative | 4,065 | $0.00 | $0 | 12,199 | Yes | Form 4 |
| Becklund IrenePAO | Jun 15 | Jun 17 | M · derivative | 4,344 | $0.00 | $0 | 30,415 | Yes | Form 4 |
| Becklund IrenePAO | Jun 15 | Jun 17 | M · derivative | 1,392 | $0.00 | $0 | 15,322 | Yes | Form 4 |
| Becklund IrenePAO | Jun 15 | Jun 17 | M · derivative | 3,879 | $0.00 | $0 | 58,197 | Yes | Form 4 |
| Chi MichaelChief Operating Officer | Jun 15 | Jun 17 | M | 86,264 | not reported | not reported | 493,850 | Yes | Form 4 |
| Chi MichaelChief Operating Officer | Jun 15 | Jun 17 | F | 47,699 | $30.17 | $1,439,079 | 446,151 | Yes | Form 4 |
| Chi MichaelChief Operating Officer | Jun 15 | Jun 17 | M · derivative | 16,496 | $0.00 | $0 | 16,496 | Yes | Form 4 |
| Chi MichaelChief Operating Officer | Jun 15 | Jun 17 | M · derivative | 16,297 | $0.00 | $0 | 48,892 | Yes | Form 4 |
| Chi MichaelChief Operating Officer | Jun 15 | Jun 17 | M · derivative | 19,358 | $0.00 | $0 | 135,509 | Yes | Form 4 |
| Chi MichaelChief Operating Officer | Jun 15 | Jun 17 | M · derivative | 10,599 | $0.00 | $0 | 116,592 | Yes | Form 4 |
| Chi MichaelChief Operating Officer | Jun 15 | Jun 17 | M · derivative | 23,514 | $0.00 | $0 | 352,708 | Yes | Form 4 |
| Autor Deborah M.Chief Policy Officer | Jun 15 | Jun 17 | M | 32,919 | not reported | not reported | 64,357 | No | Form 4 |
| Autor Deborah M.Chief Policy Officer | Jun 15 | Jun 17 | F | 15,396 | $30.17 | $464,497 | 48,961 | No | Form 4 |
| Autor Deborah M.Chief Policy Officer | Jun 15 | Jun 17 | M · derivative | 32,919 | $0.00 | $0 | 460,873 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Jun 15 | Jun 17 | M | 71,616 | not reported | not reported | 335,683 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Jun 15 | Jun 17 | F | 39,541 | $30.17 | $1,192,952 | 296,142 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Jun 15 | Jun 17 | M · derivative | 18,334 | $0.00 | $0 | 55,004 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Jun 15 | Jun 17 | M · derivative | 22,988 | $0.00 | $0 | 160,917 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Jun 15 | Jun 17 | M · derivative | 11,483 | $0.00 | $0 | 126,307 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Jun 15 | Jun 17 | M · derivative | 18,811 | $0.00 | $0 | 282,167 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Jun 15 | Jun 17 | M | 25,926 | not reported | not reported | 213,897 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Jun 15 | Jun 17 | F | 8,310 | $30.17 | $250,713 | 205,587 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Jun 15 | Jun 17 | M · derivative | 8,148 | $0.00 | $0 | 16,298 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Jun 15 | Jun 17 | M · derivative | 4,840 | $0.00 | $0 | 33,877 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Jun 15 | Jun 17 | M · derivative | 3,533 | $0.00 | $0 | 38,864 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Jun 15 | Jun 17 | M · derivative | 9,405 | $0.00 | $0 | 141,084 | No | Form 4 |
| Manuel Anja | Jun 15 | Jun 15 | M | 10,040 | not reported | not reported | 38,671 | No | Form 4 |
| Manuel Anja | Jun 15 | Jun 15 | M · derivative | 10,040 | $0.00 | $0 | 10,040 | No | Form 4 |
| Payne Christopher D | Jun 15 | Jun 15 | M | 10,040 | not reported | not reported | 33,671 | No | Form 4 |
| Payne Christopher D | Jun 15 | Jun 15 | M | 647 | not reported | not reported | 34,318 | No | Form 4 |
| Payne Christopher D | Jun 15 | Jun 15 | M · derivative | 10,040 | $0.00 | $0 | 10,040 | No | Form 4 |
| Payne Christopher D | Jun 15 | Jun 15 | M · derivative | 647 | $0.00 | $0 | not reported | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Jun 15 | Jun 15 | M | 435 | not reported | not reported | 187,971 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Jun 15 | Jun 15 | M · derivative | 435 | $0.00 | $0 | not reported | No | Form 4 |
| Wells David B | Jun 15 | Jun 15 | M | 957 | not reported | not reported | 229,030 | No | Form 4 |
| Wells David B | Jun 15 | Jun 15 | M · derivative | 957 | $0.00 | $0 | not reported | No | Form 4 |
| Cosgrove Delos M. | Jun 11 | Jun 15 | M | 3,656 | not reported | not reported | 67,995 | No | Form 4 |
| Cosgrove Delos M. | Jun 11 | Jun 15 | M · derivative | 3,656 | $0.00 | $0 | not reported | No | Form 4 |
| Manuel Anja | Jun 11 | Jun 15 | M | 3,656 | not reported | not reported | 28,631 | No | Form 4 |
| Manuel Anja | Jun 11 | Jun 15 | M · derivative | 3,656 | $0.00 | $0 | not reported | No | Form 4 |
| Pendarvis Christiane | Jun 11 | Jun 15 | M | 3,656 | not reported | not reported | 55,430 | No | Form 4 |
| Pendarvis Christiane | Jun 11 | Jun 15 | M · derivative | 3,656 | $0.00 | $0 | not reported | No | Form 4 |
| Payne Christopher D | Jun 11 | Jun 15 | M | 3,656 | not reported | not reported | 23,631 | No | Form 4 |
| Payne Christopher D | Jun 11 | Jun 15 | M · derivative | 3,656 | $0.00 | $0 | not reported | No | Form 4 |
| Autor Deborah M.Chief Policy Officer | Jun 11 | Jun 15 | M | 3,656 | not reported | not reported | 31,438 | No | Form 4 |
| Autor Deborah M.Chief Policy Officer | Jun 11 | Jun 15 | M · derivative | 3,656 | $0.00 | $0 | not reported | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Jun 11 | Jun 15 | M | 3,656 | not reported | not reported | 187,536 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Jun 11 | Jun 15 | M · derivative | 3,656 | $0.00 | $0 | not reported | No | Form 4 |
| Perez Garcia Andrea G | Jun 11 | Jun 15 | M | 3,656 | not reported | not reported | 83,822 | No | Form 4 |
| Perez Garcia Andrea G | Jun 11 | Jun 15 | M · derivative | 3,656 | $0.00 | $0 | not reported | No | Form 4 |
| Schultz Kare | Jun 11 | Jun 15 | M | 3,656 | not reported | not reported | 19,397 | No | Form 4 |
| Schultz Kare | Jun 11 | Jun 15 | M · derivative | 3,656 | $0.00 | $0 | not reported | No | Form 4 |
| Wells David B | Jun 11 | Jun 15 | M | 3,656 | not reported | not reported | 228,073 | No | Form 4 |
| Wells David B | Jun 11 | Jun 15 | M · derivative | 3,656 | $0.00 | $0 | not reported | No | Form 4 |
| Wells David B | May 26 | May 26 | P | 48,400 | $24.24 | Purchase +$1,173,216 | 224,417 | No | Form 4 |
| Wells David B | May 20 | May 22 | A · derivative | 957 | $0.00 | $0 | 957 | No | Form 4 |
| Payne Christopher D | May 20 | May 22 | A · derivative | 647 | $0.00 | $0 | 647 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | May 20 | May 22 | A · derivative | 435 | $0.00 | $0 | 435 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | May 18 | May 19 | M | 7,950 | $5.01 | $39,830 | 270,904 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | May 18 | May 19 | S | 7,950 | $23.64 | Sale −$187,938 | 262,954 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | May 18 | May 19 | M · derivative | 7,950 | $5.01 | $39,830 | 115,900 | Yes | Form 4 |
| Boughton SoleilChief Legal Officer | Apr 20 | Apr 22 | S | 9,463 | $30.00 | Sale −$283,890 | 299,368 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Apr 20 | Apr 22 | M | 5,553 | $5.01 | $27,821 | 275,599 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Apr 20 | Apr 22 | M | 7,000 | $11.53 | $80,710 | 282,599 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Apr 20 | Apr 22 | S | 19,645 | $29.96 | Sale −$588,564 | 262,954 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Apr 20 | Apr 22 | M · derivative | 5,553 | $5.01 | $27,821 | 123,850 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Apr 20 | Apr 22 | M · derivative | 7,000 | $11.53 | $80,710 | 35,996 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Apr 17 | Apr 20 | M | 6,184 | $5.01 | $30,982 | 288,051 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Apr 17 | Apr 20 | S | 18,005 | $27.83 | Sale −$501,079 | 270,046 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Apr 17 | Apr 20 | M · derivative | 6,184 | $5.01 | $30,982 | 129,403 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Apr 16 | Apr 20 | S | 36,922 | $25.90 | Sale −$956,280 | 281,867 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Apr 9 | Apr 10 | G | 422,933 | not reported | not reported | 887,684 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Apr 9 | Apr 10 | G | 422,933 | not reported | not reported | 470,457 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Apr 6 | Apr 7 | M | 3,975 | $5.01 | $19,915 | 322,764 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Apr 6 | Apr 7 | S | 3,975 | $19.98 | Sale −$79,421 | 318,789 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Apr 6 | Apr 7 | M · derivative | 3,975 | $5.01 | $19,915 | 135,587 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Mar 20 | Mar 24 | M | 4,489 | $5.01 | $22,490 | 328,006 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Mar 20 | Mar 24 | S | 9,217 | $23.77 | Sale −$219,088 | 318,789 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Mar 20 | Mar 24 | M · derivative | 4,489 | $5.01 | $22,490 | 139,562 | Yes | Form 4 |
| Boughton SoleilChief Legal Officer | Mar 17 | Mar 18 | S | 4,812 | $24.69 | Sale −$118,808 | 308,831 | Yes | Form 4 |
| Becklund IrenePAO | Mar 17 | Mar 18 | S | 5,529 | $24.69 | Sale −$136,511 | 8,752 | Yes | Form 4 |
| Chi MichaelChief Operating Officer | Mar 17 | Mar 18 | S | 97,289 | $24.69 | Sale −$2,402,065 | 407,282 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Mar 13 | Mar 17 | F | 436,190 | $24.77 | $10,804,426 | 1,236,544 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Mar 13 | Mar 17 | M | 164,369 | not reported | not reported | 1,400,913 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Mar 13 | Mar 17 | F | 90,296 | $24.77 | $2,236,632 | 1,310,617 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Mar 13 | Mar 17 | M · derivative | 35,242 | $0.00 | $0 | not reported | No | Form 4 |
| Dudum AndrewChief Executive Officer | Mar 13 | Mar 17 | M · derivative | 35,447 | $0.00 | $0 | 141,786 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Mar 13 | Mar 17 | M · derivative | 74,530 | $0.00 | $0 | 596,239 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Mar 13 | Mar 17 | M · derivative | 19,150 | $0.00 | $0 | 229,805 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Mar 13 | Mar 17 | F | 146,577 | $24.77 | $3,630,712 | 294,395 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Mar 13 | Mar 17 | M | 41,421 | not reported | not reported | 335,816 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Mar 13 | Mar 17 | F | 22,173 | $24.77 | $549,225 | 313,643 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Mar 13 | Mar 17 | M · derivative | 10,916 | $0.00 | $0 | not reported | No | Form 4 |
| Boughton SoleilChief Legal Officer | Mar 13 | Mar 17 | M · derivative | 12,223 | $0.00 | $0 | 48,892 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Mar 13 | Mar 17 | M · derivative | 12,099 | $0.00 | $0 | 96,792 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Mar 13 | Mar 17 | M · derivative | 6,183 | $0.00 | $0 | 74,194 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Mar 13 | Mar 17 | M | 16,522 | not reported | not reported | 186,462 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Mar 13 | Mar 17 | F | 4,022 | $24.77 | $99,625 | 182,440 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Mar 13 | Mar 17 | M · derivative | 8,149 | $0.00 | $0 | 24,446 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Mar 13 | Mar 17 | M · derivative | 4,840 | $0.00 | $0 | 38,717 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Mar 13 | Mar 17 | M · derivative | 3,533 | $0.00 | $0 | 42,397 | No | Form 4 |
| Autor Deborah M.Chief Policy Officer | Mar 13 | Mar 17 | M | 32,919 | not reported | not reported | 39,094 | No | Form 4 |
| Autor Deborah M.Chief Policy Officer | Mar 13 | Mar 17 | F | 11,312 | $24.77 | $280,198 | 27,782 | No | Form 4 |
| Autor Deborah M.Chief Policy Officer | Mar 13 | Mar 17 | M · derivative | 32,919 | $0.00 | $0 | 493,792 | No | Form 4 |
| Becklund IrenePAO | Mar 13 | Mar 17 | M | 17,987 | not reported | not reported | 20,113 | No | Form 4 |
| Becklund IrenePAO | Mar 13 | Mar 17 | F | 5,832 | $24.77 | $144,459 | 14,281 | No | Form 4 |
| Becklund IrenePAO | Mar 13 | Mar 17 | M · derivative | 1,872 | $0.00 | $0 | not reported | No | Form 4 |
| Becklund IrenePAO | Mar 13 | Mar 17 | M · derivative | 4,020 | $0.00 | $0 | not reported | No | Form 4 |
| Becklund IrenePAO | Mar 13 | Mar 17 | M · derivative | 2,291 | $0.00 | $0 | 2,291 | No | Form 4 |
| Becklund IrenePAO | Mar 13 | Mar 17 | M · derivative | 4,067 | $0.00 | $0 | 16,264 | No | Form 4 |
| Becklund IrenePAO | Mar 13 | Mar 17 | M · derivative | 4,345 | $0.00 | $0 | 34,759 | No | Form 4 |
| Becklund IrenePAO | Mar 13 | Mar 17 | M · derivative | 1,392 | $0.00 | $0 | 16,714 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Mar 13 | Mar 17 | F | 226,081 | $24.77 | $5,600,026 | 276,226 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Mar 13 | Mar 17 | M | 105,200 | not reported | not reported | 381,426 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Mar 13 | Mar 17 | F | 57,909 | $24.77 | $1,434,406 | 323,517 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Mar 13 | Mar 17 | M · derivative | 52,396 | $0.00 | $0 | not reported | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Mar 13 | Mar 17 | M · derivative | 18,334 | $0.00 | $0 | 73,338 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Mar 13 | Mar 17 | M · derivative | 22,988 | $0.00 | $0 | 183,905 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Mar 13 | Mar 17 | M · derivative | 11,482 | $0.00 | $0 | 137,790 | No | Form 4 |
| Chi MichaelChief Operating Officer | Mar 13 | Mar 17 | F | 198,542 | $24.77 | $4,917,885 | 471,677 | No | Form 4 |
| Chi MichaelChief Operating Officer | Mar 13 | Mar 17 | M | 72,108 | not reported | not reported | 543,785 | No | Form 4 |
| Chi MichaelChief Operating Officer | Mar 13 | Mar 17 | F | 39,214 | $24.77 | $971,331 | 504,571 | No | Form 4 |
| Chi MichaelChief Operating Officer | Mar 13 | Mar 17 | M · derivative | 9,357 | $0.00 | $0 | not reported | No | Form 4 |
| Chi MichaelChief Operating Officer | Mar 13 | Mar 17 | M · derivative | 16,495 | $0.00 | $0 | 32,992 | No | Form 4 |
| Chi MichaelChief Operating Officer | Mar 13 | Mar 17 | M · derivative | 16,298 | $0.00 | $0 | 65,189 | No | Form 4 |
| Chi MichaelChief Operating Officer | Mar 13 | Mar 17 | M · derivative | 19,359 | $0.00 | $0 | 154,867 | No | Form 4 |
| Chi MichaelChief Operating Officer | Mar 13 | Mar 17 | M · derivative | 10,599 | $0.00 | $0 | 127,191 | No | Form 4 |
| Pendarvis Christiane | Mar 13 | Mar 17 | M | 15,211 | not reported | not reported | 51,774 | No | Form 4 |
| Pendarvis Christiane | Mar 13 | Mar 17 | M · derivative | 15,211 | $0.00 | $0 | not reported | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Mar 11 | Mar 13 | A · derivative | 300,978 | $0.00 | $0 | 300,978 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Mar 11 | Mar 13 | A · derivative | 413,844 | $0.00 | $0 | 413,844 | No | Form 4 |
| Elshenawy MohamedCTO | Mar 11 | Mar 13 | A · derivative | 376,222 | $0.00 | $0 | 376,222 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Mar 11 | Mar 13 | A · derivative | 188,111 | $0.00 | $0 | 188,111 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Mar 11 | Mar 13 | A · derivative | 150,489 | $0.00 | $0 | 150,489 | No | Form 4 |
| Autor Deborah M.Chief Policy Officer | Mar 11 | Mar 13 | A · derivative | 526,711 | $0.00 | $0 | 526,711 | No | Form 4 |
| Chi MichaelChief Operating Officer | Mar 11 | Mar 13 | A · derivative | 376,222 | $0.00 | $0 | 376,222 | No | Form 4 |
| Becklund IrenePAO | Mar 11 | Mar 13 | A · derivative | 62,076 | $0.00 | $0 | 62,076 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Feb 27 | Mar 2 | S | 4,651 | $15.21 | Sale −$70,742 | 440,972 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Feb 23 | Feb 25 | A | 794,002 | $0.00 | $0 | 1,672,734 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Feb 23 | Feb 25 | A | 273,794 | $0.00 | $0 | 445,623 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Feb 23 | Feb 25 | A | 410,690 | $0.00 | $0 | 502,307 | No | Form 4 |
| Chi MichaelChief Operating Officer | Feb 23 | Feb 25 | A | 365,058 | $0.00 | $0 | 670,219 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Feb 3 | Feb 4 | M | 5,262 | $5.01 | $26,363 | 96,879 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Feb 3 | Feb 4 | S | 5,262 | $26.44 | Sale −$139,127 | 91,617 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Feb 3 | Feb 4 | M · derivative | 5,262 | $5.01 | $26,363 | 144,051 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Jan 20 | Jan 21 | M | 7,317 | $5.01 | $36,658 | 98,934 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Jan 20 | Jan 21 | M | 1,750 | $11.53 | $20,178 | 100,684 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Jan 20 | Jan 21 | S | 9,067 | $30.34 | Sale −$275,093 | 91,617 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Jan 20 | Jan 21 | M · derivative | 7,317 | $5.01 | $36,658 | 149,313 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Jan 20 | Jan 21 | M · derivative | 1,750 | $11.53 | $20,178 | 42,996 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Jan 5 | Jan 7 | M | 2,178 | $5.01 | $10,912 | 96,879 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Jan 5 | Jan 7 | M | 3,808 | $11.53 | $43,906 | 100,687 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Jan 5 | Jan 7 | S | 9,070 | $33.79 | Sale −$306,475 | 91,617 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Jan 5 | Jan 7 | M · derivative | 2,178 | $5.01 | $10,912 | 156,630 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Jan 5 | Jan 7 | M · derivative | 3,808 | $11.53 | $43,906 | 44,746 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Dec 22, 2025 | Dec 23, 2025 | S | 23,090 | $35.72 | Sale −$824,775 | 94,333 | Yes | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Dec 17, 2025 | Dec 18, 2025 | S | 10,021 | $36.71 | Sale −$367,871 | 169,940 | Yes | Form 4 |
| Autor Deborah M.Chief Policy Officer | Dec 17, 2025 | Dec 18, 2025 | S | 7,054 | $36.71 | Sale −$258,952 | 6,175 | Yes | Form 4 |
| Becklund IrenePAO | Dec 17, 2025 | Dec 18, 2025 | S | 8,411 | $36.71 | Sale −$308,768 | 2,126 | Yes | Form 4 |
| Chi MichaelChief Operating Officer | Dec 17, 2025 | Dec 18, 2025 | S | 13,750 | $36.71 | Sale −$504,763 | 305,161 | Yes | Form 4 |
| Autor Deborah M.Chief Policy Officer | Dec 15, 2025 | Dec 16, 2025 | M | 7,054 | not reported | not reported | 13,229 | No | Form 4 |
| Autor Deborah M.Chief Policy Officer | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 7,054 | $0.00 | $0 | 14,110 | No | Form 4 |
| Chi MichaelChief Operating Officer | Dec 15, 2025 | Dec 16, 2025 | M | 72,106 | not reported | not reported | 358,781 | No | Form 4 |
| Chi MichaelChief Operating Officer | Dec 15, 2025 | Dec 16, 2025 | F | 39,870 | $36.25 | $1,445,288 | 318,911 | No | Form 4 |
| Chi MichaelChief Operating Officer | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 9,356 | $0.00 | $0 | 9,357 | No | Form 4 |
| Chi MichaelChief Operating Officer | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 16,496 | $0.00 | $0 | 49,487 | No | Form 4 |
| Chi MichaelChief Operating Officer | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 16,297 | $0.00 | $0 | 81,487 | No | Form 4 |
| Chi MichaelChief Operating Officer | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 19,358 | $0.00 | $0 | 174,226 | No | Form 4 |
| Chi MichaelChief Operating Officer | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 10,599 | $0.00 | $0 | 137,790 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Dec 15, 2025 | Dec 16, 2025 | M | 105,201 | not reported | not reported | 175,433 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Dec 15, 2025 | Dec 16, 2025 | F | 58,010 | $36.25 | $2,102,863 | 117,423 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 52,395 | $0.00 | $0 | 52,396 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 18,335 | $0.00 | $0 | 91,672 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 22,988 | $0.00 | $0 | 206,893 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 11,483 | $0.00 | $0 | 149,272 | No | Form 4 |
| Becklund IrenePAO | Dec 15, 2025 | Dec 16, 2025 | M | 17,986 | not reported | not reported | 19,404 | No | Form 4 |
| Becklund IrenePAO | Dec 15, 2025 | Dec 16, 2025 | F | 8,867 | $36.25 | $321,429 | 10,537 | No | Form 4 |
| Becklund IrenePAO | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 1,871 | $0.00 | $0 | 1,872 | No | Form 4 |
| Becklund IrenePAO | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 4,019 | $0.00 | $0 | 4,020 | No | Form 4 |
| Becklund IrenePAO | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 2,291 | $0.00 | $0 | 4,582 | No | Form 4 |
| Becklund IrenePAO | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 4,066 | $0.00 | $0 | 20,331 | No | Form 4 |
| Becklund IrenePAO | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 4,345 | $0.00 | $0 | 39,104 | No | Form 4 |
| Becklund IrenePAO | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 1,394 | $0.00 | $0 | 18,106 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Dec 15, 2025 | Dec 16, 2025 | M | 164,369 | not reported | not reported | 969,392 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Dec 15, 2025 | Dec 16, 2025 | F | 90,660 | $36.25 | $3,286,425 | 878,732 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 35,242 | $0.00 | $0 | 35,242 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 35,446 | $0.00 | $0 | 177,233 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 74,530 | $0.00 | $0 | 670,769 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 19,151 | $0.00 | $0 | 248,955 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Dec 15, 2025 | Dec 16, 2025 | M | 16,521 | not reported | not reported | 186,461 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Dec 15, 2025 | Dec 16, 2025 | F | 6,500 | $36.25 | $235,625 | 179,961 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 8,149 | $0.00 | $0 | 32,595 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 4,839 | $0.00 | $0 | 43,557 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 3,533 | $0.00 | $0 | 45,930 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Dec 15, 2025 | Dec 16, 2025 | M | 41,421 | not reported | not reported | 194,646 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Dec 15, 2025 | Dec 16, 2025 | F | 22,817 | $36.25 | $827,116 | 171,829 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 10,916 | $0.00 | $0 | 10,916 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 12,223 | $0.00 | $0 | 61,115 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 12,099 | $0.00 | $0 | 108,891 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Dec 15, 2025 | Dec 16, 2025 | M · derivative | 6,183 | $0.00 | $0 | 80,377 | No | Form 4 |
| Perez Garcia Andrea G | Dec 9, 2025 | Dec 10, 2025 | S | 2,500 | $39.17 | Sale −$97,925 | 80,166 | No | Form 4 |
| Chi MichaelChief Operating Officer | Dec 1, 2025 | Dec 2, 2025 | G | 5,000 | $0.00 | $0 | 286,675 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Nov 28, 2025 | Dec 2, 2025 | G | 1,078,549 | $0.00 | $0 | not reported | No | Form 4 |
| Dudum AndrewChief Executive Officer | Nov 28, 2025 | Dec 2, 2025 | G | 1,078,549 | $0.00 | $0 | 1,080,972 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Nov 24, 2025 | Nov 25, 2025 | S | 2,631 | $35.22 | Sale −$92,664 | 153,225 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Nov 17, 2025 | Nov 19, 2025 | M | 7,615 | $11.53 | $87,801 | 77,847 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Nov 17, 2025 | Nov 19, 2025 | M | 15,572 | $5.01 | $78,016 | 93,419 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Nov 17, 2025 | Nov 19, 2025 | S | 23,187 | $36.81 | Sale −$853,513 | 70,232 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Nov 17, 2025 | Nov 19, 2025 | M · derivative | 7,615 | $11.53 | $87,801 | 48,554 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Nov 17, 2025 | Nov 19, 2025 | M · derivative | 15,572 | $5.01 | $78,016 | 158,808 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Nov 12, 2025 | Nov 12, 2025 | G | 1,954,379 | $0.00 | $0 | not reported | No | Form 4 |
| Dudum AndrewChief Executive Officer | Nov 12, 2025 | Nov 12, 2025 | G | 1,954,379 | $0.00 | $0 | 3,004,071 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Nov 10, 2025 | Nov 12, 2025 | J | 260,000 | $0.00 | $0 | 2,423 | No | Form 4 |
| Dudum AndrewChief Executive Officer | Nov 10, 2025 | Nov 12, 2025 | G | 1,049,692 | $0.00 | $0 | not reported | No | Form 4 |
| Dudum AndrewChief Executive Officer | Nov 10, 2025 | Nov 12, 2025 | G | 1,049,692 | $0.00 | $0 | 1,049,692 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Nov 10, 2025 | Nov 12, 2025 | S | 2,637 | $42.53 | Sale −$112,152 | 155,856 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Nov 7, 2025 | Nov 12, 2025 | G | 262,423 | $0.00 | $0 | not reported | No | Form 4 |
| Dudum AndrewChief Executive Officer | Nov 7, 2025 | Nov 12, 2025 | G | 262,423 | $0.00 | $0 | 262,423 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Oct 27, 2025 | Oct 28, 2025 | S | 2,637 | $50.10 | Sale −$132,114 | 158,493 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Oct 17, 2025 | Oct 20, 2025 | M | 7,785 | $5.01 | $39,003 | 78,017 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Oct 17, 2025 | Oct 20, 2025 | M | 3,807 | $11.53 | $43,895 | 81,824 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Oct 17, 2025 | Oct 20, 2025 | S | 11,592 | $57.13 | Sale −$662,251 | 70,232 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Oct 17, 2025 | Oct 20, 2025 | M · derivative | 7,785 | $5.01 | $39,003 | 174,380 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Oct 17, 2025 | Oct 20, 2025 | M · derivative | 3,807 | $11.53 | $43,895 | 56,169 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Oct 16, 2025 | Oct 20, 2025 | S | 2,792 | $62.65 | Sale −$174,919 | 92,523 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Oct 16, 2025 | Oct 20, 2025 | S | 39,111 | $62.70 | Sale −$2,452,260 | 55,947 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Oct 16, 2025 | Oct 20, 2025 | S | 8,423 | $63.46 | Sale −$534,524 | 47,524 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Oct 16, 2025 | Oct 20, 2025 | M | 17,001 | $2.43 | $41,312 | 109,524 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Oct 16, 2025 | Oct 20, 2025 | S | 17,001 | $62.69 | Sale −$1,065,793 | 92,523 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Oct 16, 2025 | Oct 20, 2025 | M | 108,334 | $2.43 | $263,252 | 200,857 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Oct 16, 2025 | Oct 20, 2025 | S | 39,531 | $62.71 | Sale −$2,478,989 | 161,326 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Oct 16, 2025 | Oct 20, 2025 | S | 10,469 | $63.49 | Sale −$664,677 | 150,857 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Oct 16, 2025 | Oct 20, 2025 | S | 39,332 | $62.70 | Sale −$2,466,116 | 111,525 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Oct 16, 2025 | Oct 20, 2025 | S | 2,335 | $63.39 | Sale −$148,016 | 109,190 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Oct 16, 2025 | Oct 20, 2025 | S | 16,667 | $62.70 | Sale −$1,045,021 | 92,523 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Oct 16, 2025 | Oct 20, 2025 | M · derivative | 17,001 | $2.43 | $41,312 | 17,005 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Oct 16, 2025 | Oct 20, 2025 | M · derivative | 108,334 | $2.43 | $263,252 | 431,395 | Yes | Form 4 |
| Boughton SoleilChief Legal Officer | Oct 13, 2025 | Oct 14, 2025 | S | 2,637 | $54.38 | Sale −$143,400 | 161,130 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Oct 10, 2025 | Oct 14, 2025 | M | 900 | $6.82 | $6,138 | 292,339 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Oct 10, 2025 | Oct 14, 2025 | S | 900 | $58.25 | Sale −$52,425 | 291,439 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Oct 10, 2025 | Oct 14, 2025 | M · derivative | 900 | $6.82 | $6,138 | 115,362 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Oct 3, 2025 | Oct 7, 2025 | M | 7,787 | $5.01 | $39,013 | 78,019 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Oct 3, 2025 | Oct 7, 2025 | M | 3,808 | $11.53 | $43,906 | 81,827 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Oct 3, 2025 | Oct 7, 2025 | S | 11,595 | $57.72 | Sale −$669,263 | 70,232 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Oct 3, 2025 | Oct 7, 2025 | M · derivative | 7,787 | $5.01 | $39,013 | 182,165 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Oct 3, 2025 | Oct 7, 2025 | M · derivative | 3,808 | $11.53 | $43,906 | 59,976 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Oct 1, 2025 | Oct 2, 2025 | M | 250 | $11.53 | $2,883 | 291,689 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Oct 1, 2025 | Oct 2, 2025 | S | 250 | $56.00 | Sale −$14,000 | 291,439 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Oct 1, 2025 | Oct 2, 2025 | M · derivative | 250 | $11.53 | $2,883 | 47,106 | Yes | Form 4 |
| Boughton SoleilChief Legal Officer | Sep 29, 2025 | Sep 30, 2025 | S | 2,637 | $58.79 | Sale −$155,029 | 163,767 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Sep 29, 2025 | Sep 30, 2025 | M | 49,832 | $5.01 | $249,658 | 155,232 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Sep 29, 2025 | Sep 30, 2025 | S | 85,000 | $60.20 | Sale −$5,117,000 | 70,232 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Sep 29, 2025 | Sep 30, 2025 | M · derivative | 49,832 | $5.01 | $249,658 | 189,952 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Sep 24, 2025 | Sep 25, 2025 | M | 2,100 | $5.01 | $10,521 | 293,539 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Sep 24, 2025 | Sep 25, 2025 | S | 2,100 | $56.52 | Sale −$118,692 | 291,439 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Sep 24, 2025 | Sep 25, 2025 | M · derivative | 2,100 | $5.01 | $10,521 | 174,042 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Mar 7, 2025 | Sep 25, 2025 | G | 5,700 | $0.00 | $0 | 291,439 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Sep 22, 2025 | Sep 24, 2025 | S | 23,584 | $57.74 | Sale −$1,361,740 | 105,400 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Sep 17, 2025 | Sep 19, 2025 | S | 65,110 | $50.57 | Sale −$3,292,613 | 95,315 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Sep 17, 2025 | Sep 19, 2025 | S | 13,749 | $50.50 | Sale −$694,325 | 297,139 | Yes | Form 4 |
| Becklund IrenePAO | Sep 17, 2025 | Sep 19, 2025 | S | 8,410 | $50.50 | Sale −$424,705 | 1,418 | Yes | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Sep 17, 2025 | Sep 19, 2025 | S | 10,021 | $50.50 | Sale −$506,061 | 169,940 | Yes | Form 4 |
| Boughton SoleilChief Legal Officer | Sep 17, 2025 | Sep 19, 2025 | S | 2,637 | $50.50 | Sale −$133,169 | 166,404 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Sep 16, 2025 | Sep 17, 2025 | S | 2,792 | $54.21 | Sale −$151,354 | 160,425 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Sep 16, 2025 | Sep 17, 2025 | S | 28,652 | $52.90 | Sale −$1,515,691 | 113,940 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Sep 16, 2025 | Sep 17, 2025 | S | 18,882 | $53.85 | Sale −$1,016,796 | 95,058 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Sep 16, 2025 | Sep 17, 2025 | M | 17,001 | $2.43 | $41,312 | 177,426 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Sep 16, 2025 | Sep 17, 2025 | S | 17,001 | $53.79 | Sale −$914,484 | 160,425 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Sep 16, 2025 | Sep 17, 2025 | M | 108,334 | $2.43 | $263,252 | 268,759 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Sep 16, 2025 | Sep 17, 2025 | S | 16,667 | $53.79 | Sale −$896,518 | 252,092 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Sep 16, 2025 | Sep 17, 2025 | S | 23,938 | $53.08 | Sale −$1,270,629 | 228,154 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Sep 16, 2025 | Sep 17, 2025 | S | 17,729 | $53.81 | Sale −$953,997 | 210,425 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Sep 16, 2025 | Sep 17, 2025 | S | 32,190 | $53.03 | Sale −$1,707,036 | 178,235 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Sep 16, 2025 | Sep 17, 2025 | S | 17,810 | $53.81 | Sale −$958,356 | 160,425 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Sep 16, 2025 | Sep 17, 2025 | M · derivative | 17,001 | $2.43 | $41,312 | 34,006 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Sep 16, 2025 | Sep 17, 2025 | M · derivative | 108,334 | $2.43 | $263,252 | 539,729 | Yes | Form 4 |
| Schultz Kare | Sep 15, 2025 | Sep 17, 2025 | M | 6,623 | not reported | not reported | 15,741 | No | Form 4 |
| Schultz Kare | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 6,623 | $0.00 | $0 | 13,247 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Sep 15, 2025 | Sep 17, 2025 | M | 105,199 | not reported | not reported | 222,005 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Sep 15, 2025 | Sep 17, 2025 | F | 58,021 | $53.96 | $3,130,813 | 163,984 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Sep 15, 2025 | Sep 17, 2025 | M | 110,000 | $5.01 | $551,100 | 273,984 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Sep 15, 2025 | Sep 17, 2025 | S | 117,792 | $55.25 | Sale −$6,508,008 | 156,192 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Sep 15, 2025 | Sep 17, 2025 | S | 27,208 | $55.79 | Sale −$1,517,934 | 128,984 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 52,395 | $0.00 | $0 | 104,791 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 18,334 | $0.00 | $0 | 110,007 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 22,988 | $0.00 | $0 | 229,881 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 11,482 | $0.00 | $0 | 160,755 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 110,000 | $5.01 | $551,100 | 239,784 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Sep 15, 2025 | Sep 17, 2025 | M | 164,368 | not reported | not reported | 253,889 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Sep 15, 2025 | Sep 17, 2025 | F | 90,672 | $53.96 | $4,892,661 | 163,217 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 35,242 | $0.00 | $0 | 70,484 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 35,447 | $0.00 | $0 | 212,679 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 74,529 | $0.00 | $0 | 745,299 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 19,150 | $0.00 | $0 | 268,106 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Sep 15, 2025 | Sep 17, 2025 | M | 250 | $11.53 | $2,883 | 278,904 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Sep 15, 2025 | Sep 17, 2025 | M | 1,800 | $6.82 | $12,276 | 280,704 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Sep 15, 2025 | Sep 17, 2025 | M | 2,100 | $5.01 | $10,521 | 282,804 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Sep 15, 2025 | Sep 17, 2025 | S | 4,150 | $56.00 | Sale −$232,400 | 278,654 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Sep 15, 2025 | Sep 17, 2025 | M | 72,106 | not reported | not reported | 350,760 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Sep 15, 2025 | Sep 17, 2025 | F | 39,872 | $53.96 | $2,151,493 | 310,888 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 250 | $11.53 | $2,883 | 47,356 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 1,800 | $6.82 | $12,276 | 116,262 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 2,100 | $5.01 | $10,521 | 176,142 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 9,356 | $0.00 | $0 | 18,713 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 16,495 | $0.00 | $0 | 65,983 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 16,297 | $0.00 | $0 | 97,784 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 19,359 | $0.00 | $0 | 193,584 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 10,599 | $0.00 | $0 | 148,389 | Yes | Form 4 |
| Becklund IrenePAO | Sep 15, 2025 | Sep 17, 2025 | M | 17,983 | not reported | not reported | 18,695 | No | Form 4 |
| Becklund IrenePAO | Sep 15, 2025 | Sep 17, 2025 | F | 8,867 | $53.96 | $478,463 | 9,828 | No | Form 4 |
| Becklund IrenePAO | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 1,871 | $0.00 | $0 | 3,743 | No | Form 4 |
| Becklund IrenePAO | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 4,019 | $0.00 | $0 | 8,039 | No | Form 4 |
| Becklund IrenePAO | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 2,291 | $0.00 | $0 | 6,873 | No | Form 4 |
| Becklund IrenePAO | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 4,065 | $0.00 | $0 | 24,397 | No | Form 4 |
| Becklund IrenePAO | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 4,345 | $0.00 | $0 | 43,449 | No | Form 4 |
| Becklund IrenePAO | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 1,392 | $0.00 | $0 | 19,500 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Sep 15, 2025 | Sep 17, 2025 | M | 41,420 | not reported | not reported | 191,870 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Sep 15, 2025 | Sep 17, 2025 | F | 22,829 | $53.96 | $1,231,853 | 169,041 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 10,915 | $0.00 | $0 | 21,832 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 12,223 | $0.00 | $0 | 73,338 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 12,099 | $0.00 | $0 | 120,990 | No | Form 4 |
| Boughton SoleilChief Legal Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 6,183 | $0.00 | $0 | 86,560 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Sep 15, 2025 | Sep 17, 2025 | M | 16,521 | not reported | not reported | 186,461 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Sep 15, 2025 | Sep 17, 2025 | F | 6,500 | $53.96 | $350,740 | 179,961 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 8,148 | $0.00 | $0 | 40,744 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 4,840 | $0.00 | $0 | 48,396 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 3,533 | $0.00 | $0 | 49,463 | No | Form 4 |
| Okupe OluyemiChief Financial Officer | Aug 26, 2025 | Aug 28, 2025 | M | 11,581 | $5.01 | $58,021 | 128,387 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Aug 26, 2025 | Aug 28, 2025 | S | 11,581 | $43.69 | Sale −$505,974 | 116,806 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Aug 26, 2025 | Aug 28, 2025 | M · derivative | 11,581 | $5.01 | $58,021 | 349,784 | Yes | Form 4 |
| Boughton SoleilChief Legal Officer | Aug 25, 2025 | Aug 26, 2025 | S | 2,571 | $44.53 | Sale −$114,487 | 150,450 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Aug 18, 2025 | Aug 20, 2025 | S | 47,534 | $45.05 | Sale −$2,141,407 | 142,592 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Aug 18, 2025 | Aug 20, 2025 | S | 2,792 | $44.97 | Sale −$125,556 | 89,521 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Aug 18, 2025 | Aug 20, 2025 | M | 17,001 | $2.43 | $41,312 | 106,522 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Aug 18, 2025 | Aug 20, 2025 | S | 17,001 | $45.14 | Sale −$767,425 | 89,521 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Aug 18, 2025 | Aug 20, 2025 | M | 108,334 | $2.43 | $263,252 | 197,855 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Aug 18, 2025 | Aug 20, 2025 | S | 41,667 | $45.11 | Sale −$1,879,598 | 156,188 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Aug 18, 2025 | Aug 20, 2025 | S | 50,000 | $45.04 | Sale −$2,252,000 | 106,188 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Aug 18, 2025 | Aug 20, 2025 | S | 16,667 | $44.92 | Sale −$748,682 | 89,521 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Aug 18, 2025 | Aug 20, 2025 | M · derivative | 17,001 | $2.43 | $41,312 | 51,007 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Aug 18, 2025 | Aug 20, 2025 | M · derivative | 108,334 | $2.43 | $263,252 | 648,063 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Aug 13, 2025 | Aug 15, 2025 | M | 11,581 | $5.01 | $58,021 | 65,665 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Aug 13, 2025 | Aug 15, 2025 | S | 11,581 | $48.05 | Sale −$556,467 | 116,806 | Yes | Form 4 |
| Okupe OluyemiChief Financial Officer | Aug 13, 2025 | Aug 15, 2025 | M · derivative | 11,581 | $5.01 | $58,021 | 361,365 | Yes | Form 4 |
| Boughton SoleilChief Legal Officer | Aug 11, 2025 | Aug 12, 2025 | S | 2,572 | $51.64 | Sale −$132,818 | 153,021 | Yes | Form 4 |
| Dudum AndrewChief Executive Officer | Aug 7, 2025 | Aug 11, 2025 | S | 660,000 | $50.58 | Sale −$33,382,800 | 2,214,769 | No | Form 4 |
| Pendarvis Christiane | Aug 6, 2025 | Aug 8, 2025 | A · derivative | 3,656 | $0.00 | $0 | 3,656 | No | Form 4 |
| Schultz Kare | Aug 6, 2025 | Aug 8, 2025 | A · derivative | 3,656 | $0.00 | $0 | 3,656 | No | Form 4 |
| Manuel Anja | Aug 6, 2025 | Aug 8, 2025 | A · derivative | 3,656 | $0.00 | $0 | 3,656 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Aug 6, 2025 | Aug 8, 2025 | S | 60,000 | $53.58 | Sale −$3,214,800 | 169,940 | No | Form 4 |
| Carroll Patrick HarrisonChief Medical Officer | Aug 6, 2025 | Aug 8, 2025 | A · derivative | 3,656 | $0.00 | $0 | 3,656 | No | Form 4 |
| Autor Deborah M. | Aug 6, 2025 | Aug 8, 2025 | A · derivative | 3,656 | $0.00 | $0 | 3,656 | No | Form 4 |
| Cosgrove Delos M. | Aug 6, 2025 | Aug 8, 2025 | A · derivative | 3,656 | $0.00 | $0 | 3,656 | No | Form 4 |
| Perez Garcia Andrea G | Aug 6, 2025 | Aug 8, 2025 | A · derivative | 3,656 | $0.00 | $0 | 3,656 | No | Form 4 |
| Payne Christopher D | Aug 6, 2025 | Aug 8, 2025 | A · derivative | 3,656 | $0.00 | $0 | 3,656 | No | Form 4 |
| Wells David B | Aug 6, 2025 | Aug 8, 2025 | A · derivative | 3,656 | $0.00 | $0 | 3,656 | No | Form 4 |
| Chi MichaelChief Commercial Officer | Aug 1, 2025 | Aug 4, 2025 | M | 250 | $11.53 | $2,883 | 278,904 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Aug 1, 2025 | Aug 4, 2025 | S | 250 | $64.44 | Sale −$16,110 | 278,654 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Aug 1, 2025 | Aug 4, 2025 | M · derivative | 250 | $11.53 | $2,883 | 47,606 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Jul 31, 2025 | Aug 4, 2025 | M | 3,600 | $13.90 | $50,040 | 282,254 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Jul 31, 2025 | Aug 4, 2025 | M | 14,700 | $5.01 | $73,647 | 296,954 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Jul 31, 2025 | Aug 4, 2025 | M | 6,300 | $6.82 | $42,966 | 303,254 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Jul 31, 2025 | Aug 4, 2025 | M | 1,750 | $11.53 | $20,178 | 305,004 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Jul 31, 2025 | Aug 4, 2025 | S | 26,350 | $67.00 | Sale −$1,765,450 | 278,654 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Jul 31, 2025 | Aug 4, 2025 | M · derivative | 3,600 | $13.90 | $50,040 | 7,800 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Jul 31, 2025 | Aug 4, 2025 | M · derivative | 14,700 | $5.01 | $73,647 | 178,242 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Jul 31, 2025 | Aug 4, 2025 | M · derivative | 6,300 | $6.82 | $42,966 | 118,062 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Jul 31, 2025 | Aug 4, 2025 | M · derivative | 1,750 | $11.53 | $20,178 | 47,856 | Yes | Form 4 |
| Boughton SoleilChief Legal Officer | Jul 28, 2025 | Jul 29, 2025 | S | 2,572 | $58.70 | Sale −$150,976 | 155,593 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Jul 24, 2025 | Jul 25, 2025 | M | 2,100 | $5.01 | $10,521 | 280,754 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Jul 24, 2025 | Jul 25, 2025 | S | 2,100 | $57.52 | Sale −$120,792 | 278,654 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Jul 24, 2025 | Jul 25, 2025 | M · derivative | 2,100 | $5.01 | $10,521 | 192,942 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Jul 23, 2025 | Jul 25, 2025 | M | 12,600 | $5.01 | $63,126 | 291,254 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Jul 23, 2025 | Jul 25, 2025 | M | 900 | $6.82 | $6,138 | 292,154 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Jul 23, 2025 | Jul 25, 2025 | M | 250 | $11.53 | $2,883 | 292,404 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Jul 23, 2025 | Jul 25, 2025 | S | 13,750 | $56.00 | Sale −$770,000 | 278,654 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Jul 23, 2025 | Jul 25, 2025 | M · derivative | 12,600 | $5.01 | $63,126 | 195,042 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Jul 23, 2025 | Jul 25, 2025 | M · derivative | 900 | $6.82 | $6,138 | 124,362 | Yes | Form 4 |
| Chi MichaelChief Commercial Officer | Jul 23, 2025 | Jul 25, 2025 | M · derivative | 250 | $11.53 | $2,883 | 49,606 | Yes | Form 4 |