JAZZJazz Pharmaceuticals plc
- Market cap
- $13.89B
- as of 2026-10-23
- Latest close
- $214.00
- as of 2026-10-23
- Sector
- Healthcare
- as of 2026-10-24
- Industry
- Biotechnology
- as of 2026-10-24
Cluster
No cluster in the last 90 days under the default rule (14d · ≥2 insiders · all roles).
Form 4 historysince 2023-11-14
| Insider | Traded | Filed | Type | Shares | Price | Value | Owned after | 10b5-1 plan | Filing |
|---|---|---|---|---|---|---|---|---|---|
| Gala Renee DPresident & CEO | Oct 6 | Oct 7 | S | 2,000 | $236.40 | Sale −$472,800 | 141,394 | Yes | Form 4 |
| Cozadd Bruce C | Oct 1 | Oct 5 | S | 6,000 | $230.33 | Sale −$1,381,980 | 345,875 | Yes | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Sep 10 | Sep 14 | S | 1,200 | $240.94 | Sale −$289,128 | 47,671 | Yes | Form 4 |
| Gala Renee DPresident & CEO | Sep 8 | Sep 10 | F | 1,967 | $246.81 | $485,475 | 145,394 | Yes | Form 4 |
| Gala Renee DPresident & CEO | Sep 8 | Sep 10 | S | 2,000 | $243.03 | Sale −$486,060 | 143,394 | Yes | Form 4 |
| Henderson Mary ElizabethSVP, Technical Operations | Sep 8 | Sep 10 | F | 1,412 | $243.03 | $343,158 | 23,830 | No | Form 4 |
| Henderson Mary ElizabethSVP, Technical Operations | Sep 8 | Sep 10 | F | 15 | $241.20 | $3,618 | 23,815 | No | Form 4 |
| Cozadd Bruce C | Sep 1 | Sep 2 | S | 6,000 | $250.13 | Sale −$1,500,780 | 351,875 | Yes | Form 4 |
| Riedel Norbert G | Aug 31 | Sep 2 | F | 14 | $244.64 | $3,425 | 8,615 | No | Form 4 |
| Riedel Norbert G | Aug 31 | Sep 2 | F | 1,692 | $241.39 | $408,432 | 6,923 | No | Form 4 |
| Love Ted W | Aug 31 | Sep 2 | F | 6 | $244.06 | $1,464 | 3,126 | No | Form 4 |
| Love Ted W | Aug 31 | Sep 2 | F | 737 | $241.39 | $177,904 | 2,389 | No | Form 4 |
| Cozadd Bruce C | Aug 31 | Sep 2 | F | 10 | $244.06 | $2,441 | 359,084 | Yes | Form 4 |
| Cozadd Bruce C | Aug 31 | Sep 2 | F | 1,209 | $241.39 | $291,841 | 357,875 | Yes | Form 4 |
| Enright Patrick G | Aug 31 | Sep 2 | F | 14 | $244.64 | $3,425 | 22,970 | No | Form 4 |
| Enright Patrick G | Aug 31 | Sep 2 | F | 1,692 | $241.39 | $408,432 | 21,278 | No | Form 4 |
| Winningham Rick E | Aug 31 | Sep 2 | F | 1,692 | $241.39 | $408,432 | 9,480 | No | Form 4 |
| Winningham Rick E | Aug 31 | Sep 2 | F | 14 | $244.64 | $3,425 | 9,466 | No | Form 4 |
| McSharry Heather Ann | Aug 31 | Sep 2 | F | 15 | $244.64 | $3,670 | 20,039 | No | Form 4 |
| McSharry Heather Ann | Aug 31 | Sep 2 | F | 1,840 | $241.39 | $444,158 | 18,199 | No | Form 4 |
| Hamill Laura | Aug 31 | Sep 2 | F | 14 | $244.06 | $3,417 | 8,524 | No | Form 4 |
| Hamill Laura | Aug 31 | Sep 2 | F | 1,692 | $241.39 | $408,432 | 6,832 | No | Form 4 |
| Cook Jennifer E. | Aug 31 | Sep 2 | F | 14 | $244.06 | $3,417 | 12,428 | No | Form 4 |
| Cook Jennifer E. | Aug 31 | Sep 2 | F | 1,692 | $241.39 | $408,432 | 10,736 | No | Form 4 |
| Smith Mark Douglas | Aug 31 | Sep 2 | F | 14 | $244.64 | $3,425 | 11,271 | No | Form 4 |
| Smith Mark Douglas | Aug 31 | Sep 2 | F | 1,692 | $241.39 | $408,432 | 9,579 | No | Form 4 |
| Henderson Mary ElizabethSVP, Technical Operations | Aug 31 | Sep 2 | F | 2,076 | $241.39 | $501,126 | 25,258 | No | Form 4 |
| Henderson Mary ElizabethSVP, Technical Operations | Aug 31 | Sep 2 | F | 16 | $244.64 | $3,914 | 25,242 | No | Form 4 |
| Kennedy Patrick | Aug 31 | Sep 2 | F | 15 | $244.06 | $3,661 | 8,292 | No | Form 4 |
| Kennedy Patrick | Aug 31 | Sep 2 | F | 1,840 | $241.39 | $444,158 | 6,452 | No | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Aug 27 | Aug 31 | M | 26,116 | $113.10 | $2,953,720 | 111,223 | Yes | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Aug 27 | Aug 31 | M | 884 | $113.10 | $99,980 | 112,107 | Yes | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Aug 27 | Aug 31 | M | 27,584 | $137.12 | $3,782,318 | 139,691 | Yes | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Aug 27 | Aug 31 | M | 2,916 | $137.12 | $399,842 | 142,607 | Yes | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Aug 27 | Aug 31 | S | 18,187 | $247.86 | Sale −$4,507,830 | 124,420 | Yes | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Aug 27 | Aug 31 | S | 11,423 | $248.67 | Sale −$2,840,557 | 112,997 | Yes | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Aug 27 | Aug 31 | S | 18,113 | $250.02 | Sale −$4,528,612 | 94,884 | Yes | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Aug 27 | Aug 31 | S | 19,639 | $250.60 | Sale −$4,921,533 | 75,245 | Yes | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Aug 27 | Aug 31 | S | 9,259 | $251.95 | Sale −$2,332,805 | 65,986 | Yes | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Aug 27 | Aug 31 | S | 300 | $252.76 | Sale −$75,828 | 65,686 | Yes | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Aug 27 | Aug 31 | M · derivative | 884 | $113.10 | $99,980 | not reported | Yes | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Aug 27 | Aug 31 | M · derivative | 2,916 | $137.12 | $399,842 | not reported | Yes | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Aug 27 | Aug 31 | M · derivative | 26,116 | $113.10 | $2,953,720 | not reported | Yes | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Aug 27 | Aug 31 | M · derivative | 27,584 | $137.12 | $3,782,318 | not reported | Yes | Form 4 |
| Riedel Norbert G | Aug 5 | Aug 7 | A | 1,605 | $0.00 | $0 | 8,629 | No | Form 4 |
| Love Ted W | Aug 5 | Aug 7 | A | 1,605 | $0.00 | $0 | 3,132 | No | Form 4 |
| Cozadd Bruce C | Aug 5 | Aug 7 | A | 1,605 | $0.00 | $0 | 362,287 | No | Form 4 |
| Enright Patrick G | Aug 5 | Aug 7 | A | 1,605 | $0.00 | $0 | 22,984 | No | Form 4 |
| Winningham Rick E | Aug 5 | Aug 7 | A | 1,605 | $0.00 | $0 | 11,172 | No | Form 4 |
| Mulligan Seamus | Aug 5 | Aug 7 | A | 1,605 | $0.00 | $0 | 1,184,633 | No | Form 4 |
| McSharry Heather Ann | Aug 5 | Aug 7 | A | 1,605 | $0.00 | $0 | 20,054 | No | Form 4 |
| Hamill Laura | Aug 5 | Aug 7 | A | 1,605 | $0.00 | $0 | 8,538 | No | Form 4 |
| Cook Jennifer E. | Aug 5 | Aug 7 | A | 1,605 | $0.00 | $0 | 12,442 | No | Form 4 |
| Smith Mark Douglas | Aug 5 | Aug 7 | A | 1,605 | $0.00 | $0 | 11,285 | No | Form 4 |
| Pearce SamanthaEVP, Chief Commercial Officer | Aug 5 | Aug 7 | F | 780 | $261.62 | $204,064 | 47,131 | No | Form 4 |
| Kennedy Patrick | Aug 5 | Aug 7 | A | 1,605 | $0.00 | $0 | 8,307 | No | Form 4 |
| Cozadd Bruce C | Aug 3 | Aug 5 | S | 6,000 | $252.98 | Sale −$1,517,880 | 360,682 | Yes | Form 4 |
| Cozadd Bruce C | Jul 1 | Jul 6 | S | 6,000 | $240.47 | Sale −$1,442,820 | 366,682 | Yes | Form 4 |
| Gala Renee DPresident & CEO | Jun 30 | Jul 2 | F | 4,835 | $237.72 | $1,149,376 | 147,361 | No | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Jun 30 | Jul 2 | F | 3,764 | $237.72 | $894,778 | 85,107 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Jun 30 | Jul 2 | F | 2,678 | $237.72 | $636,614 | 48,871 | No | Form 4 |
| Pearce SamanthaEVP, Chief Commercial Officer | Jun 30 | Jul 2 | F | 2,527 | $237.72 | $600,718 | 47,911 | No | Form 4 |
| Johnson Philip LEVP & Chief Financial Officer | Jun 30 | Jul 2 | F | 3,343 | $237.72 | $794,698 | 56,431 | No | Form 4 |
| Smith Mark Douglas | Jun 15 | Jun 17 | S | 1,157 | $230.55 | Sale −$266,746 | 9,680 | Yes | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Jun 10 | Jun 12 | S | 1,200 | $231.83 | Sale −$278,196 | 51,549 | Yes | Form 4 |
| Gala Renee DPresident & CEO | Jun 3 | Jun 5 | G | 600 | $0.00 | $0 | 152,196 | No | Form 4 |
| Cozadd Bruce C | Jun 1 | Jun 3 | S | 6,000 | $235.12 | Sale −$1,410,720 | 372,682 | Yes | Form 4 |
| Mulligan Seamus | May 28 | Jun 1 | M | 3,415 | $138.08 | $471,543 | 1,183,028 | No | Form 4 |
| Mulligan Seamus | May 28 | Jun 1 | M · derivative | 3,415 | $138.08 | $471,543 | not reported | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | May 28 | Jun 1 | S | 1,192 | $236.97 | Sale −$282,468 | 52,626 | Yes | Form 4 |
| Pearce SamanthaEVP, Chief Commercial Officer | May 28 | Jun 1 | M | 6,907 | $109.45 | $755,971 | 57,179 | No | Form 4 |
| Pearce SamanthaEVP, Chief Commercial Officer | May 28 | Jun 1 | S | 6,907 | $235.41 | Sale −$1,625,977 | 50,272 | No | Form 4 |
| Pearce SamanthaEVP, Chief Commercial Officer | May 28 | Jun 1 | M · derivative | 6,907 | $109.45 | $755,971 | not reported | No | Form 4 |
| Winningham Rick E | May 22 | May 27 | M | 3,415 | $138.08 | $471,543 | 12,308 | No | Form 4 |
| Winningham Rick E | May 22 | May 27 | S | 2,741 | $241.57 | Sale −$662,143 | 9,567 | No | Form 4 |
| Winningham Rick E | May 22 | May 27 | M · derivative | 3,415 | $138.08 | $471,543 | not reported | No | Form 4 |
| McSharry Heather Ann | May 22 | May 27 | S | 2,000 | $241.00 | Sale −$482,000 | 18,449 | No | Form 4 |
| Cozadd Bruce C | May 1 | May 5 | S | 6,000 | $203.33 | Sale −$1,219,980 | 378,682 | Yes | Form 4 |
| Cozadd Bruce C | Apr 1 | Apr 3 | S | 3,684 | $190.22 | Sale −$700,770 | 386,998 | Yes | Form 4 |
| Cozadd Bruce C | Apr 1 | Apr 3 | S | 2,292 | $190.94 | Sale −$437,634 | 384,706 | Yes | Form 4 |
| Cozadd Bruce C | Apr 1 | Apr 3 | S | 24 | $191.74 | Sale −$4,602 | 384,682 | Yes | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Mar 9 | Mar 9 | S | 1,287 | $182.94 | Sale −$235,444 | 6,512 | No | Form 4 |
| Cozadd Bruce C | Mar 5 | Mar 9 | F | 15,114 | $188.69 | $2,851,861 | 390,682 | No | Form 4 |
| Gala Renee DPresident & CEO | Mar 5 | Mar 9 | F | 7,065 | $188.69 | $1,333,095 | 152,630 | No | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Mar 5 | Mar 9 | F | 6,209 | $188.69 | $1,171,576 | 88,871 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Mar 5 | Mar 9 | F | 5,000 | $188.69 | $943,450 | 53,818 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Mar 5 | Mar 9 | F | 1,436 | $186.77 | $268,202 | 7,799 | No | Form 4 |
| Pearce SamanthaEVP, Chief Commercial Officer | Mar 5 | Mar 9 | F | 2,503 | $188.69 | $472,291 | 50,272 | No | Form 4 |
| Henderson Mary ElizabethSVP, Technical Operations | Mar 5 | Mar 9 | F | 1,394 | $186.75 | $260,330 | 27,334 | No | Form 4 |
| Johnson Philip LEVP & Chief Financial Officer | Mar 5 | Mar 9 | F | 2,615 | $188.69 | $493,424 | 59,608 | No | Form 4 |
| Cozadd Bruce C | Mar 3 | Mar 4 | S | 3,159 | $186.09 | Sale −$587,858 | 408,637 | Yes | Form 4 |
| Cozadd Bruce C | Mar 3 | Mar 4 | S | 2,608 | $186.73 | Sale −$486,992 | 406,029 | Yes | Form 4 |
| Cozadd Bruce C | Mar 3 | Mar 4 | S | 233 | $187.84 | Sale −$43,767 | 405,796 | Yes | Form 4 |
| Riedel Norbert G | Feb 27 | Mar 2 | M | 3,415 | $138.08 | $471,543 | 10,439 | No | Form 4 |
| Riedel Norbert G | Feb 27 | Mar 2 | S | 3,415 | $192.00 | Sale −$655,680 | 7,024 | No | Form 4 |
| Riedel Norbert G | Feb 27 | Mar 2 | M · derivative | 3,415 | $138.08 | $471,543 | not reported | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Feb 27 | Mar 2 | S | 1,117 | $190.91 | Sale −$213,246 | 9,235 | No | Form 4 |
| Love Ted W | Feb 26 | Mar 2 | A | 1,527 | $0.00 | $0 | 1,527 | No | Form 4 |
| Gala Renee DPresident & CEO | Feb 26 | Mar 2 | A | 44,465 | $0.00 | $0 | 159,695 | No | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Feb 26 | Mar 2 | A | 14,822 | $0.00 | $0 | 95,080 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 26 | Mar 2 | M | 20,125 | $113.10 | $2,276,138 | 73,464 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 26 | Mar 2 | S | 16,602 | $192.53 | Sale −$3,196,383 | 56,862 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 26 | Mar 2 | M | 875 | $113.10 | $98,963 | 57,737 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 26 | Mar 2 | S | 875 | $192.07 | Sale −$168,061 | 56,862 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 26 | Mar 2 | M | 27,084 | $137.12 | $3,713,758 | 83,946 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 26 | Mar 2 | S | 15,555 | $190.28 | Sale −$2,959,805 | 68,391 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 26 | Mar 2 | M | 2,916 | $137.12 | $399,842 | 71,307 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 26 | Mar 2 | S | 2,916 | $189.81 | Sale −$553,486 | 68,391 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 26 | Mar 2 | A | 10,079 | $0.00 | $0 | 78,470 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 26 | Mar 2 | S | 11,529 | $191.65 | Sale −$2,209,533 | 66,941 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 26 | Mar 2 | S | 3,523 | $193.58 | Sale −$681,982 | 63,418 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 26 | Mar 2 | S | 1,061 | $190.00 | Sale −$201,590 | 62,357 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 26 | Mar 2 | S | 549 | $190.80 | Sale −$104,749 | 61,808 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 26 | Mar 2 | S | 1,784 | $191.88 | Sale −$342,314 | 60,024 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 26 | Mar 2 | S | 1,009 | $192.79 | Sale −$194,525 | 59,015 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 26 | Mar 2 | S | 197 | $193.60 | Sale −$38,139 | 58,818 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 26 | Mar 2 | M · derivative | 875 | $113.10 | $98,963 | not reported | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 26 | Mar 2 | M · derivative | 2,916 | $137.12 | $399,842 | not reported | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 26 | Mar 2 | M · derivative | 20,125 | $113.10 | $2,276,138 | not reported | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 26 | Mar 2 | M · derivative | 27,084 | $137.12 | $3,713,758 | not reported | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Feb 26 | Mar 2 | A | 2,223 | $0.00 | $0 | 11,605 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Feb 26 | Mar 2 | S | 1,253 | $194.11 | Sale −$243,220 | 10,352 | No | Form 4 |
| Pearce SamanthaEVP, Chief Commercial Officer | Feb 26 | Mar 2 | A | 9,782 | $0.00 | $0 | 52,775 | No | Form 4 |
| Henderson Mary ElizabethSVP, Technical Operations | Feb 26 | Mar 2 | A | 4,447 | $0.00 | $0 | 34,071 | No | Form 4 |
| Henderson Mary ElizabethSVP, Technical Operations | Feb 26 | Mar 2 | S | 5,343 | $194.49 | Sale −$1,039,160 | 28,728 | No | Form 4 |
| Johnson Philip LEVP & Chief Financial Officer | Feb 26 | Mar 2 | A | 11,857 | $0.00 | $0 | 62,223 | No | Form 4 |
| Cozadd Bruce C | Jan 16 | Jan 21 | A | 35,917 | $0.00 | $0 | 429,249 | No | Form 4 |
| Cozadd Bruce C | Jan 16 | Jan 21 | F | 17,453 | $171.16 | $2,987,255 | 411,796 | No | Form 4 |
| Gala Renee DPresident & CEO | Jan 16 | Jan 21 | A | 12,741 | $0.00 | $0 | 120,601 | No | Form 4 |
| Gala Renee DPresident & CEO | Jan 16 | Jan 21 | F | 5,371 | $171.16 | $919,300 | 115,230 | No | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Jan 16 | Jan 21 | A | 11,699 | $0.00 | $0 | 84,398 | No | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Jan 16 | Jan 21 | F | 4,140 | $171.16 | $708,602 | 80,258 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Jan 16 | Jan 21 | A | 8,852 | $0.00 | $0 | 56,614 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Jan 16 | Jan 21 | D | 3,275 | $171.16 | $560,549 | 53,339 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Jan 16 | Jan 21 | A | 2,370 | $0.00 | $0 | 9,382 | No | Form 4 |
| Pearce SamanthaEVP, Chief Commercial Officer | Jan 16 | Jan 21 | A | 3,637 | $0.00 | $0 | 44,592 | No | Form 4 |
| Pearce SamanthaEVP, Chief Commercial Officer | Jan 16 | Jan 21 | F | 1,599 | $171.16 | $273,685 | 42,993 | No | Form 4 |
| Henderson Mary ElizabethSVP, Technical Operations | Jan 16 | Jan 21 | A | 10,116 | $0.00 | $0 | 29,624 | No | Form 4 |
| Enright Patrick G | Aug 18, 2025 | Jan 8 | J | 5,000 | $0.00 | $0 | 21,379 | No | Form 4 |
| Henderson Mary ElizabethSVP, Technical Operations | Dec 9, 2025 | Dec 11, 2025 | S | 2,238 | $169.51 | Sale −$379,363 | 19,508 | No | Form 4 |
| Gala Renee DPresident & CEO | Dec 5, 2025 | Dec 9, 2025 | F | 80 | $166.91 | $13,353 | 107,860 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Dec 5, 2025 | Dec 9, 2025 | S | 160 | $171.11 | Sale −$27,378 | 7,012 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Dec 5, 2025 | Dec 9, 2025 | M | 4,500 | $140.67 | $633,015 | 11,512 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Dec 5, 2025 | Dec 9, 2025 | S | 4,500 | $171.20 | Sale −$770,400 | 7,012 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Dec 5, 2025 | Dec 9, 2025 | M · derivative | 4,500 | $140.67 | $633,015 | not reported | No | Form 4 |
| O'Keefe Kenneth W | Dec 2, 2025 | Dec 4, 2025 | F | 603 | $173.07 | $104,361 | 25,811 | No | Form 4 |
| Cozadd Bruce C | Nov 26, 2025 | Dec 1, 2025 | M | 76,689 | $123.36 | $9,460,355 | 470,021 | No | Form 4 |
| Cozadd Bruce C | Nov 26, 2025 | Dec 1, 2025 | M | 811 | $123.36 | $100,045 | 470,832 | No | Form 4 |
| Cozadd Bruce C | Nov 26, 2025 | Dec 1, 2025 | S | 30,487 | $178.06 | Sale −$5,428,515 | 440,345 | No | Form 4 |
| Cozadd Bruce C | Nov 26, 2025 | Dec 1, 2025 | S | 8,380 | $179.23 | Sale −$1,501,947 | 431,965 | No | Form 4 |
| Cozadd Bruce C | Nov 26, 2025 | Dec 1, 2025 | S | 507 | $179.79 | Sale −$91,154 | 431,458 | No | Form 4 |
| Cozadd Bruce C | Nov 26, 2025 | Dec 1, 2025 | S | 38,126 | $177.27 | Sale −$6,758,596 | 393,332 | No | Form 4 |
| Cozadd Bruce C | Nov 26, 2025 | Dec 1, 2025 | M · derivative | 811 | $123.36 | $100,045 | not reported | No | Form 4 |
| Cozadd Bruce C | Nov 26, 2025 | Dec 1, 2025 | M · derivative | 76,689 | $123.36 | $9,460,355 | not reported | No | Form 4 |
| McSharry Heather Ann | Nov 20, 2025 | Nov 24, 2025 | M | 3,415 | $138.08 | $471,543 | 23,864 | No | Form 4 |
| McSharry Heather Ann | Nov 20, 2025 | Nov 24, 2025 | S | 3,415 | $177.78 | Sale −$607,119 | 20,449 | No | Form 4 |
| McSharry Heather Ann | Nov 20, 2025 | Nov 24, 2025 | M · derivative | 3,415 | $138.08 | $471,543 | not reported | No | Form 4 |
| Henderson Mary ElizabethSVP, Technical Operations | Nov 19, 2025 | Nov 21, 2025 | D | 1,331 | $180.40 | $240,112 | 21,746 | No | Form 4 |
| Cozadd Bruce C | Nov 20, 2025 | Nov 20, 2025 | A | 2,506 | $0.00 | $0 | 393,332 | No | Form 4 |
| Cozadd Bruce C | Nov 18, 2025 | Nov 20, 2025 | S | 3,384 | $180.09 | Sale −$609,425 | 405,442 | No | Form 4 |
| Cozadd Bruce C | Nov 18, 2025 | Nov 20, 2025 | S | 8,382 | $180.88 | Sale −$1,516,136 | 397,060 | No | Form 4 |
| Cozadd Bruce C | Nov 18, 2025 | Nov 20, 2025 | S | 5,517 | $181.81 | Sale −$1,003,046 | 391,543 | No | Form 4 |
| Cozadd Bruce C | Nov 18, 2025 | Nov 20, 2025 | S | 717 | $182.60 | Sale −$130,924 | 390,826 | No | Form 4 |
| Winningham Rick E | Nov 18, 2025 | Nov 20, 2025 | S | 5,500 | $180.86 | Sale −$994,730 | 8,893 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Nov 18, 2025 | Nov 20, 2025 | S | 69 | $181.66 | Sale −$12,535 | 7,012 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Nov 18, 2025 | Nov 20, 2025 | M | 5,250 | $136.18 | $714,945 | 12,262 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Nov 18, 2025 | Nov 20, 2025 | S | 5,250 | $182.07 | Sale −$955,868 | 7,012 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Nov 18, 2025 | Nov 20, 2025 | M · derivative | 5,250 | $136.18 | $714,945 | not reported | No | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Nov 17, 2025 | Nov 19, 2025 | S | 7,159 | $168.26 | Sale −$1,204,573 | 72,628 | Yes | Form 4 |
| Cozadd Bruce C | Oct 3, 2025 | Oct 3, 2025 | S | 3,500 | $140.00 | Sale −$490,000 | 408,826 | Yes | Form 4 |
| Cozadd Bruce C | Oct 1, 2025 | Oct 3, 2025 | S | 2,000 | $131.78 | Sale −$263,560 | 412,326 | Yes | Form 4 |
| Cozadd Bruce C | Sep 14, 2025 | Sep 17, 2025 | F | 15,647 | $126.16 | $1,974,026 | 414,326 | No | Form 4 |
| Cozadd Bruce C | Sep 2, 2025 | Sep 4, 2025 | S | 3,000 | $127.23 | Sale −$381,690 | 432,973 | Yes | Form 4 |
| Cozadd Bruce C | Sep 2, 2025 | Sep 4, 2025 | S | 3,000 | $130.00 | Sale −$390,000 | 429,973 | Yes | Form 4 |
| Winningham Rick E | Aug 8, 2025 | Aug 11, 2025 | F | 1,805 | $111.25 | $200,806 | 14,393 | No | Form 4 |
| Smith Mark Douglas | Aug 8, 2025 | Aug 11, 2025 | F | 1,805 | $111.25 | $200,806 | 10,837 | No | Form 4 |
| Riedel Norbert G | Aug 8, 2025 | Aug 11, 2025 | F | 1,805 | $111.25 | $200,806 | 7,024 | No | Form 4 |
| ORiordan Anne | Aug 8, 2025 | Aug 11, 2025 | F | 1,805 | $111.25 | $200,806 | 16,500 | No | Form 4 |
| McSharry Heather Ann | Aug 8, 2025 | Aug 11, 2025 | F | 1,959 | $111.25 | $217,939 | 20,449 | No | Form 4 |
| Kennedy Patrick | Aug 8, 2025 | Aug 11, 2025 | F | 1,959 | $111.25 | $217,939 | 6,702 | No | Form 4 |
| Hamill Laura | Aug 8, 2025 | Aug 11, 2025 | F | 1,805 | $111.25 | $200,806 | 6,933 | No | Form 4 |
| Enright Patrick G | Aug 8, 2025 | Aug 11, 2025 | F | 1,805 | $111.25 | $200,806 | 26,379 | No | Form 4 |
| Cook Jennifer E. | Aug 8, 2025 | Aug 11, 2025 | F | 1,805 | $111.25 | $200,806 | 10,837 | No | Form 4 |
| O'Keefe Kenneth W | Aug 8, 2025 | Aug 11, 2025 | F | 1,805 | $111.25 | $200,806 | 28,672 | No | Form 4 |
| Gala Renee DPresident & CEO | Aug 7, 2025 | Aug 11, 2025 | A | 18,808 | $0.00 | $0 | 107,869 | No | Form 4 |
| Mulligan Seamus | Aug 7, 2025 | Aug 11, 2025 | A | 3,507 | $0.00 | $0 | 1,179,613 | No | Form 4 |
| Winningham Rick E | Aug 7, 2025 | Aug 11, 2025 | A | 3,507 | $0.00 | $0 | 16,198 | No | Form 4 |
| Smith Mark Douglas | Aug 7, 2025 | Aug 11, 2025 | A | 3,507 | $0.00 | $0 | 12,642 | No | Form 4 |
| Riedel Norbert G | Aug 7, 2025 | Aug 11, 2025 | A | 3,507 | $0.00 | $0 | 8,829 | No | Form 4 |
| ORiordan Anne | Aug 7, 2025 | Aug 11, 2025 | A | 3,507 | $0.00 | $0 | 18,305 | No | Form 4 |
| McSharry Heather Ann | Aug 7, 2025 | Aug 11, 2025 | A | 3,507 | $0.00 | $0 | 22,408 | No | Form 4 |
| Kennedy Patrick | Aug 7, 2025 | Aug 11, 2025 | A | 3,507 | $0.00 | $0 | 8,661 | No | Form 4 |
| Hamill Laura | Aug 7, 2025 | Aug 11, 2025 | A | 3,507 | $0.00 | $0 | 8,738 | No | Form 4 |
| Enright Patrick G | Aug 7, 2025 | Aug 11, 2025 | A | 3,507 | $0.00 | $0 | 28,184 | No | Form 4 |
| Cook Jennifer E. | Aug 7, 2025 | Aug 11, 2025 | A | 3,507 | $0.00 | $0 | 12,642 | No | Form 4 |
| O'Keefe Kenneth W | Aug 7, 2025 | Aug 11, 2025 | A | 3,507 | $0.00 | $0 | 30,477 | No | Form 4 |
| Pearce SamanthaEVP, Chief Commercial Officer | Aug 5, 2025 | Aug 7, 2025 | F | 577 | $116.10 | $66,990 | 40,815 | No | Form 4 |
| Cozadd Bruce CChairman & CEO | Aug 1, 2025 | Aug 5, 2025 | S | 1,000 | $113.21 | Sale −$113,210 | 435,973 | Yes | Form 4 |
| Cozadd Bruce CChairman & CEO | Jul 1, 2025 | Jul 3, 2025 | S | 500 | $105.26 | Sale −$52,630 | 437,473 | Yes | Form 4 |
| Cozadd Bruce CChairman & CEO | Jul 1, 2025 | Jul 3, 2025 | S | 500 | $110.00 | Sale −$55,000 | 436,973 | Yes | Form 4 |
| Cozadd Bruce CChairman & CEO | Jun 3, 2025 | Jun 4, 2025 | S | 500 | $110.00 | Sale −$55,000 | 437,973 | Yes | Form 4 |
| Cozadd Bruce CChairman & CEO | Jun 2, 2025 | Jun 4, 2025 | S | 500 | $107.90 | Sale −$53,950 | 438,473 | Yes | Form 4 |
| Mulligan Seamus | May 12, 2025 | May 13, 2025 | P | 1,621 | $103.00 | Purchase +$166,963 | 101,621 | No | Form 4 |
| Mulligan Seamus | May 9, 2025 | May 13, 2025 | P | 80,684 | $98.10 | Purchase +$7,915,100 | 80,684 | No | Form 4 |
| Mulligan Seamus | May 9, 2025 | May 13, 2025 | P | 19,216 | $98.91 | Purchase +$1,900,655 | 99,900 | No | Form 4 |
| Mulligan Seamus | May 9, 2025 | May 13, 2025 | P | 100 | $99.71 | Purchase +$9,971 | 100,000 | No | Form 4 |
| Cozadd Bruce CChairman & CEO | May 2, 2025 | May 5, 2025 | S | 500 | $120.00 | Sale −$60,000 | 438,807 | Yes | Form 4 |
| Cozadd Bruce CChairman & CEO | May 1, 2025 | May 5, 2025 | S | 1,000 | $116.35 | Sale −$116,350 | 439,307 | Yes | Form 4 |
| Cozadd Bruce CChairman & CEO | Apr 1, 2025 | Apr 3, 2025 | S | 1,500 | $123.75 | Sale −$185,625 | 440,307 | Yes | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Mar 10, 2025 | Mar 12, 2025 | S | 2,403 | $138.41 | Sale −$332,599 | 79,621 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Mar 10, 2025 | Mar 11, 2025 | S | 1,140 | $137.81 | Sale −$157,103 | 7,012 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Mar 7, 2025 | Mar 11, 2025 | D | 1,333 | $138.23 | $184,261 | 8,152 | No | Form 4 |
| Henderson Mary ElizabethSVP, Technical Operations | Mar 7, 2025 | Mar 11, 2025 | D | 698 | $138.23 | $96,485 | 23,077 | No | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Mar 7, 2025 | Mar 7, 2025 | S | 5,532 | $138.21 | Sale −$764,578 | 83,572 | Yes | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Mar 7, 2025 | Mar 7, 2025 | S | 1,548 | $140.00 | Sale −$216,720 | 82,024 | Yes | Form 4 |
| Cozadd Bruce CChairman & CEO | Mar 5, 2025 | Mar 7, 2025 | D | 22,251 | $138.95 | $3,091,776 | 441,807 | No | Form 4 |
| Gala Renee DPresident & COO | Mar 5, 2025 | Mar 7, 2025 | D | 5,704 | $138.95 | $792,571 | 88,895 | No | Form 4 |
| Iannone RobertEVP, Global Head of R&D & CMO | Mar 5, 2025 | Mar 7, 2025 | D | 5,239 | $138.95 | $727,959 | 89,104 | Yes | Form 4 |
| Johnson Philip LEVP & Chief Financial Officer | Mar 5, 2025 | Mar 7, 2025 | D | 1,149 | $138.95 | $159,654 | 50,060 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Mar 5, 2025 | Mar 7, 2025 | D | 4,088 | $138.95 | $568,028 | 47,526 | No | Form 4 |
| Pearce SamanthaEVP, Chief Commercial Officer | Mar 5, 2025 | Mar 7, 2025 | D | 1,905 | $138.95 | $264,700 | 41,226 | No | Form 4 |
| Cozadd Bruce CChairman & CEO | Mar 3, 2025 | Mar 3, 2025 | S | 6,500 | $144.25 | Sale −$937,625 | 464,058 | Yes | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Feb 28, 2025 | Mar 3, 2025 | S | 773 | $143.30 | Sale −$110,771 | 9,485 | No | Form 4 |
| Cozadd Bruce CChairman & CEO | Feb 27, 2025 | Mar 3, 2025 | A | 30,814 | $0.00 | $0 | 470,558 | Yes | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 27, 2025 | Mar 3, 2025 | S | 3,800 | $144.87 | Sale −$550,506 | 33,318 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 27, 2025 | Mar 3, 2025 | A | 12,518 | $0.00 | $0 | 45,836 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Feb 27, 2025 | Mar 3, 2025 | A | 5,778 | $0.00 | $0 | 51,614 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Feb 27, 2025 | Mar 3, 2025 | M | 4,500 | $113.10 | $508,950 | 12,737 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Feb 27, 2025 | Mar 3, 2025 | S | 4,500 | $144.42 | Sale −$649,890 | 8,237 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Feb 27, 2025 | Mar 3, 2025 | M | 313 | $123.36 | $38,612 | 8,550 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Feb 27, 2025 | Mar 3, 2025 | S | 313 | $144.42 | Sale −$45,203 | 8,237 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Feb 27, 2025 | Mar 3, 2025 | D | 371 | $142.43 | $52,842 | 7,866 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Feb 27, 2025 | Mar 3, 2025 | D | 497 | $142.43 | $70,788 | 7,369 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Feb 27, 2025 | Mar 3, 2025 | A | 2,889 | $0.00 | $0 | 10,258 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Feb 27, 2025 | Mar 3, 2025 | M · derivative | 4,500 | $113.10 | $508,950 | not reported | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Feb 27, 2025 | Mar 3, 2025 | M · derivative | 313 | $123.36 | $38,612 | not reported | No | Form 4 |
| Johnson Philip LEVP & Chief Financial Officer | Feb 27, 2025 | Mar 3, 2025 | A | 15,407 | $0.00 | $0 | 43,505 | No | Form 4 |
| Johnson Philip LEVP & Chief Financial Officer | Feb 27, 2025 | Mar 3, 2025 | A | 7,704 | $0.00 | $0 | 51,209 | No | Form 4 |
| Gala Renee DPresident & COO | Feb 27, 2025 | Mar 3, 2025 | A | 23,111 | $0.00 | $0 | 83,044 | No | Form 4 |
| Gala Renee DPresident & COO | Feb 27, 2025 | Mar 3, 2025 | A | 11,555 | $0.00 | $0 | 94,599 | No | Form 4 |
| Pearce SamanthaEVP, Chief Commercial Officer | Feb 27, 2025 | Mar 3, 2025 | A | 11,941 | $0.00 | $0 | 37,353 | No | Form 4 |
| Pearce SamanthaEVP, Chief Commercial Officer | Feb 27, 2025 | Mar 3, 2025 | A | 5,778 | $0.00 | $0 | 43,131 | No | Form 4 |
| Henderson Mary ElizabethSVP, Technical Operations | Feb 27, 2025 | Mar 3, 2025 | A | 5,392 | $0.00 | $0 | 19,923 | No | Form 4 |
| Henderson Mary ElizabethSVP, Technical Operations | Feb 27, 2025 | Mar 3, 2025 | A | 3,852 | $0.00 | $0 | 23,775 | No | Form 4 |
| Iannone RobertEVP, G R&D and CMO | Feb 27, 2025 | Mar 3, 2025 | A | 17,718 | $0.00 | $0 | 85,484 | No | Form 4 |
| Iannone RobertEVP, G R&D and CMO | Feb 27, 2025 | Mar 3, 2025 | A | 8,859 | $0.00 | $0 | 94,343 | No | Form 4 |
| Cozadd Bruce CChairman & CEO | Feb 3, 2025 | Feb 5, 2025 | S | 1,500 | $122.31 | Sale −$183,465 | 439,744 | Yes | Form 4 |
| Pearce SamanthaEVP, Chief Commercial Officer | Jan 17, 2025 | Jan 22, 2025 | A | 2,533 | $0.00 | $0 | 26,777 | No | Form 4 |
| Pearce SamanthaEVP, Chief Commercial Officer | Jan 17, 2025 | Jan 22, 2025 | F | 1,365 | $122.62 | $167,376 | 25,412 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Jan 17, 2025 | Jan 22, 2025 | A | 5,864 | $0.00 | $0 | 39,023 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Jan 17, 2025 | Jan 22, 2025 | F | 1,905 | $122.62 | $233,591 | 37,118 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Jan 17, 2025 | Jan 22, 2025 | A | 1,641 | $0.00 | $0 | 8,237 | No | Form 4 |
| Gala Renee DPresident & COO | Jan 17, 2025 | Jan 22, 2025 | A | 7,741 | $0.00 | $0 | 63,233 | No | Form 4 |
| Gala Renee DPresident & COO | Jan 17, 2025 | Jan 22, 2025 | F | 3,300 | $122.62 | $404,646 | 59,933 | No | Form 4 |
| Cozadd Bruce CChairman & CEO | Jan 17, 2025 | Jan 22, 2025 | A | 29,559 | $0.00 | $0 | 455,084 | No | Form 4 |
| Cozadd Bruce CChairman & CEO | Jan 17, 2025 | Jan 22, 2025 | F | 13,840 | $122.62 | $1,697,061 | 441,244 | No | Form 4 |
| Iannone RobertEVP, G R&D and CMO | Jan 17, 2025 | Jan 22, 2025 | A | 7,506 | $0.00 | $0 | 69,947 | No | Form 4 |
| Iannone RobertEVP, G R&D and CMO | Jan 17, 2025 | Jan 22, 2025 | F | 2,181 | $122.62 | $267,434 | 67,766 | No | Form 4 |
| Cozadd Bruce CChairman & CEO | Jan 2, 2025 | Jan 6, 2025 | S | 1,500 | $123.43 | Sale −$185,145 | 425,525 | No | Form 4 |
| Gala Renee DPresident & COO | Dec 5, 2024 | Dec 9, 2024 | F | 80 | $123.45 | $9,876 | 55,492 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Dec 2, 2024 | Dec 4, 2024 | S | 53 | $122.49 | Sale −$6,492 | 6,596 | No | Form 4 |
| Cozadd Bruce CChairman & CEO | Dec 2, 2024 | Dec 4, 2024 | S | 2,000 | $121.17 | Sale −$242,340 | 427,025 | Yes | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Nov 8, 2024 | Nov 13, 2024 | S | 3,700 | $123.41 | Sale −$456,617 | 33,048 | No | Form 4 |
| Cozadd Bruce CChairman & CEO | Nov 1, 2024 | Nov 5, 2024 | S | 1,000 | $110.84 | Sale −$110,840 | 428,976 | No | Form 4 |
| Henderson Mary ElizabethSVP, Technical Operations | Sep 6, 2024 | Sep 11, 2024 | S | 1,410 | $108.30 | Sale −$152,703 | 14,531 | No | Form 4 |
| Cook Jennifer E. | Aug 6, 2024 | Aug 6, 2024 | F | 1,484 | $111.35 | $165,243 | 9,135 | No | Form 4 |
| McSharry Heather Ann | Aug 6, 2024 | Aug 6, 2024 | F | 1,608 | $111.35 | $179,051 | 18,901 | No | Form 4 |
| O'Keefe Kenneth W | Aug 6, 2024 | Aug 6, 2024 | F | 1,484 | $111.35 | $165,243 | 26,970 | No | Form 4 |
| ORiordan Anne | Aug 6, 2024 | Aug 6, 2024 | F | 1,484 | $111.35 | $165,243 | 14,798 | No | Form 4 |
| Riedel Norbert G | Aug 6, 2024 | Aug 6, 2024 | F | 1,484 | $111.35 | $165,243 | 5,322 | No | Form 4 |
| Smith Mark Douglas | Aug 6, 2024 | Aug 6, 2024 | F | 1,484 | $111.35 | $165,243 | 9,135 | No | Form 4 |
| Winningham Rick E | Aug 6, 2024 | Aug 6, 2024 | F | 1,484 | $111.35 | $165,243 | 12,691 | No | Form 4 |
| Hamill Laura | Aug 2, 2024 | Aug 6, 2024 | A | 3,731 | $0.00 | $0 | 5,231 | No | Form 4 |
| Kennedy Patrick | Aug 2, 2024 | Aug 6, 2024 | A | 3,731 | $0.00 | $0 | 5,154 | No | Form 4 |
| Mulligan Seamus | Aug 2, 2024 | Aug 6, 2024 | A | 3,731 | $0.00 | $0 | 1,176,106 | No | Form 4 |
| Pearce SamanthaEVP, Chief Commercial Officer | Aug 2, 2024 | Aug 6, 2024 | A | 6,996 | $0.00 | $0 | 24,078 | No | Form 4 |
| Cook Jennifer E. | Aug 2, 2024 | Aug 6, 2024 | A | 3,731 | $0.00 | $0 | 10,619 | No | Form 4 |
| McSharry Heather Ann | Aug 2, 2024 | Aug 6, 2024 | A | 3,731 | $0.00 | $0 | 20,509 | No | Form 4 |
| O'Keefe Kenneth W | Aug 2, 2024 | Aug 6, 2024 | A | 3,731 | $0.00 | $0 | 28,454 | No | Form 4 |
| ORiordan Anne | Aug 2, 2024 | Aug 6, 2024 | A | 3,731 | $0.00 | $0 | 16,282 | No | Form 4 |
| Riedel Norbert G | Aug 2, 2024 | Aug 6, 2024 | A | 3,731 | $0.00 | $0 | 6,806 | No | Form 4 |
| Smith Mark Douglas | Aug 2, 2024 | Aug 6, 2024 | A | 3,731 | $0.00 | $0 | 10,619 | No | Form 4 |
| Winningham Rick E | Aug 2, 2024 | Aug 6, 2024 | A | 3,731 | $0.00 | $0 | 14,175 | No | Form 4 |
| Enright Patrick G | Aug 2, 2024 | Aug 6, 2024 | A | 3,731 | $0.00 | $0 | 24,677 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Jun 7, 2024 | Jun 11, 2024 | S | 163 | $108.83 | Sale −$17,739 | 6,596 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | May 3, 2024 | May 7, 2024 | S | 5,000 | $109.65 | Sale −$548,250 | 36,629 | No | Form 4 |
| Gala Renee DPresident & COO | Apr 5, 2024 | Apr 9, 2024 | F | 1,736 | $115.21 | $200,005 | 55,357 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Mar 7, 2024 | Mar 8, 2024 | S | 1,768 | $116.98 | Sale −$206,821 | 6,596 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Mar 6, 2024 | Mar 8, 2024 | S | 1,236 | $120.85 | Sale −$149,371 | 9,064 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Mar 6, 2024 | Mar 8, 2024 | S | 700 | $117.51 | Sale −$82,257 | 8,364 | No | Form 4 |
| Cozadd Bruce CChairman & CEO | Mar 5, 2024 | Mar 7, 2024 | F | 22,436 | $117.53 | $2,636,903 | 429,809 | No | Form 4 |
| Iannone RobertEVP, Global Head of R&D | Mar 5, 2024 | Mar 7, 2024 | F | 4,294 | $117.53 | $504,674 | 62,226 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Mar 5, 2024 | Mar 7, 2024 | F | 3,432 | $117.53 | $403,363 | 41,629 | No | Form 4 |
| Pearce SamanthaSVP, Head of Europe & Internat | Mar 5, 2024 | Mar 7, 2024 | F | 2,474 | $117.53 | $290,769 | 16,922 | No | Form 4 |
| Gala Renee DPresident & COO | Mar 5, 2024 | Mar 7, 2024 | F | 3,622 | $117.53 | $425,694 | 57,093 | No | Form 4 |
| Johnson Philip LEVP & Chief Financial Officer | Mar 1, 2024 | Mar 5, 2024 | A | 15,932 | $0.00 | $0 | 15,932 | No | Form 4 |
| Johnson Philip LEVP & Chief Financial Officer | Mar 1, 2024 | Mar 5, 2024 | P | 12,000 | $119.65 | Purchase +$1,435,800 | 27,932 | No | Form 4 |
| Kennedy Patrick | Mar 1, 2024 | Mar 5, 2024 | A | 1,423 | $0.00 | $0 | 1,423 | No | Form 4 |
| Cozadd Bruce CChairman & CEO | Mar 1, 2024 | Mar 5, 2024 | A | 50,187 | $0.00 | $0 | 452,245 | No | Form 4 |
| Gala Renee DPresident & COO | Mar 1, 2024 | Mar 5, 2024 | A | 19,916 | $0.00 | $0 | 60,715 | No | Form 4 |
| Iannone RobertEVP, Global Head of R&D | Mar 1, 2024 | Mar 5, 2024 | A | 16,928 | $0.00 | $0 | 66,520 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Mar 1, 2024 | Mar 5, 2024 | A | 12,348 | $0.00 | $0 | 45,061 | No | Form 4 |
| Pearce SamanthaSVP, Head of Europe & Internat | Mar 1, 2024 | Mar 5, 2024 | A | 5,065 | $0.00 | $0 | 19,396 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Mar 1, 2024 | Mar 5, 2024 | A | 2,987 | $0.00 | $0 | 10,300 | No | Form 4 |
| Henderson Mary ElizabethSVP, Technical Operations | Mar 1, 2024 | Mar 5, 2024 | A | 5,178 | $0.00 | $0 | 15,941 | No | Form 4 |
| Carr PatriciaSVP, Chief Accounting Officer | Jan 17, 2024 | Jan 19, 2024 | A | 1,327 | $0.00 | $0 | 7,363 | No | Form 4 |
| Cozadd Bruce CChairman & CEO | Jan 17, 2024 | Jan 19, 2024 | A | 26,545 | $0.00 | $0 | 414,303 | No | Form 4 |
| Cozadd Bruce CChairman & CEO | Jan 17, 2024 | Jan 19, 2024 | F | 12,245 | $119.13 | $1,458,747 | 402,058 | No | Form 4 |
| Gala Renee DPresident & COO | Jan 17, 2024 | Jan 19, 2024 | A | 7,079 | $0.00 | $0 | 44,003 | No | Form 4 |
| Gala Renee DPresident & COO | Jan 17, 2024 | Jan 19, 2024 | F | 3,204 | $119.13 | $381,693 | 40,799 | No | Form 4 |
| Iannone RobertEVP, Global Head of R&D | Jan 17, 2024 | Jan 19, 2024 | A | 5,970 | $0.00 | $0 | 51,322 | No | Form 4 |
| Iannone RobertEVP, Global Head of R&D | Jan 17, 2024 | Jan 19, 2024 | F | 1,730 | $119.13 | $206,095 | 49,592 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Jan 17, 2024 | Jan 19, 2024 | A | 5,087 | $0.00 | $0 | 34,369 | No | Form 4 |
| Patil Neena MEVP & Chief Legal Officer | Jan 17, 2024 | Jan 19, 2024 | F | 1,656 | $119.13 | $197,279 | 32,713 | No | Form 4 |
| Pearce SamanthaSVP, Head of Europe & Internat | Jan 17, 2024 | Jan 19, 2024 | A | 2,210 | $0.00 | $0 | 15,369 | No | Form 4 |
| Pearce SamanthaSVP, Head of Europe & Internat | Jan 17, 2024 | Jan 19, 2024 | F | 1,038 | $119.13 | $123,657 | 14,331 | No | Form 4 |
| Cook Jennifer E. | Dec 4, 2023 | Dec 6, 2023 | S | 417 | $119.27 | Sale −$49,736 | 6,888 | No | Form 4 |
| Smith Mark Douglas | Dec 4, 2023 | Dec 6, 2023 | S | 417 | $119.27 | Sale −$49,736 | 6,888 | No | Form 4 |
| Gala Renee DPresident & COO | Nov 10, 2023 | Nov 14, 2023 | A | 772 | $0.00 | $0 | 36,887 | No | Form 4 |