KNSAKiniksa Pharmaceuticals International, plc
- Market cap
- $5.90B
- as of 2026-10-23
- Latest close
- $76.73
- as of 2026-10-23
- Sector
- Healthcare
- as of 2026-10-24
- Industry
- Drug Manufacturers - Specialty & Generic
- as of 2026-10-24
Cluster
No cluster in the last 90 days under the default rule (14d · ≥2 insiders · all roles).
Form 4 historysince 2023-10-06
Showing the latest 500 of 1010 transactions.
| Insider | Traded | Filed | Type | Shares | Price | Value | Owned after | 10b5-1 plan | Filing |
|---|---|---|---|---|---|---|---|---|---|
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 3 | Sep 3 | S | 4,600 | $80.30 | Sale −$369,380 | 29,062 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 1 | Sep 3 | M | 3,932 | not reported | not reported | 31,629 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 1 | Sep 3 | M | 2,558 | not reported | not reported | 34,187 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 1 | Sep 3 | M | 2,362 | not reported | not reported | 36,549 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 1 | Sep 3 | M | 2,644 | not reported | not reported | 39,193 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 1 | Sep 3 | F | 5,531 | $79.28 | $438,498 | 33,662 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 1 | Sep 3 | A · derivative | 3,650 | $0.00 | $0 | 3,650 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 1 | Sep 3 | A · derivative | 14,600 | $79.28 | $1,157,488 | 14,600 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 1 | Sep 3 | M · derivative | 2,644 | $0.00 | $0 | 7,931 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 1 | Sep 3 | M · derivative | 2,362 | $0.00 | $0 | 4,725 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 1 | Sep 3 | M · derivative | 2,558 | $0.00 | $0 | 2,557 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 1 | Sep 3 | M · derivative | 3,932 | $0.00 | $0 | not reported | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | M | 9,991 | not reported | not reported | 86,165 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | M | 6,481 | not reported | not reported | 92,646 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | M | 6,237 | not reported | not reported | 98,883 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | M | 8,609 | not reported | not reported | 107,492 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | F | 15,144 | $79.28 | $1,200,616 | 92,348 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | A · derivative | 30,050 | $0.00 | $0 | 30,050 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | A · derivative | 120,150 | $79.28 | $9,525,492 | 120,150 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | M · derivative | 8,609 | $0.00 | $0 | 25,826 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | M · derivative | 6,237 | $0.00 | $0 | 12,475 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | M · derivative | 6,481 | $0.00 | $0 | 6,481 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | M · derivative | 9,991 | $0.00 | $0 | not reported | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | M | 9,991 | not reported | not reported | 86,165 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | M | 6,481 | not reported | not reported | 92,646 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | M | 6,237 | not reported | not reported | 98,883 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | M | 8,609 | not reported | not reported | 107,492 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | F | 15,144 | $79.28 | $1,200,616 | 92,348 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | A · derivative | 30,050 | $0.00 | $0 | 30,050 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | A · derivative | 120,150 | $79.28 | $9,525,492 | 120,150 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | M · derivative | 8,609 | $0.00 | $0 | 25,826 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | M · derivative | 6,237 | $0.00 | $0 | 12,475 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | M · derivative | 6,481 | $0.00 | $0 | 6,481 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1 | Sep 3 | M · derivative | 9,991 | $0.00 | $0 | not reported | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 1 | Sep 3 | M | 2,497 | not reported | not reported | 68,120 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 1 | Sep 3 | M | 1,624 | not reported | not reported | 69,744 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 1 | Sep 3 | M | 1,750 | not reported | not reported | 71,494 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 1 | Sep 3 | M | 2,457 | not reported | not reported | 73,951 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 1 | Sep 3 | F | 4,029 | $79.28 | $319,419 | 69,922 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 1 | Sep 3 | A · derivative | 6,700 | $0.00 | $0 | 6,700 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 1 | Sep 3 | A · derivative | 26,750 | $79.28 | $2,120,740 | 26,750 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 1 | Sep 3 | M · derivative | 2,457 | $0.00 | $0 | 7,371 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 1 | Sep 3 | M · derivative | 1,750 | $0.00 | $0 | 3,500 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 1 | Sep 3 | M · derivative | 1,624 | $0.00 | $0 | 1,624 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 1 | Sep 3 | M · derivative | 2,497 | $0.00 | $0 | not reported | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 1 | Sep 3 | M | 2,694 | not reported | not reported | 18,848 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 1 | Sep 3 | M | 1,750 | not reported | not reported | 20,598 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 1 | Sep 3 | M | 1,591 | not reported | not reported | 22,189 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 1 | Sep 3 | M | 3,069 | not reported | not reported | 25,258 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 1 | Sep 3 | F | 4,404 | $79.28 | $349,149 | 20,854 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 1 | Sep 3 | A · derivative | 7,800 | $0.00 | $0 | 7,800 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 1 | Sep 3 | A · derivative | 31,150 | $79.28 | $2,469,572 | 31,150 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 1 | Sep 3 | M · derivative | 3,069 | $0.00 | $0 | 9,206 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 1 | Sep 3 | M · derivative | 1,591 | $0.00 | $0 | 3,182 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 1 | Sep 3 | M · derivative | 1,750 | $0.00 | $0 | 1,750 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 1 | Sep 3 | M · derivative | 2,694 | $0.00 | $0 | not reported | No | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Sep 1 | Sep 3 | M | 2,477 | not reported | not reported | 14,506 | No | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Sep 1 | Sep 3 | M | 1,611 | not reported | not reported | 16,117 | No | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Sep 1 | Sep 3 | M | 1,740 | not reported | not reported | 17,857 | No | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Sep 1 | Sep 3 | M | 2,457 | not reported | not reported | 20,314 | No | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Sep 1 | Sep 3 | F | 4,007 | $79.28 | $317,675 | 16,307 | No | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Sep 1 | Sep 3 | A · derivative | 9,250 | $0.00 | $0 | 9,250 | No | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Sep 1 | Sep 3 | A · derivative | 36,950 | $79.28 | $2,929,396 | 36,950 | No | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Sep 1 | Sep 3 | M · derivative | 2,457 | $0.00 | $0 | 7,371 | No | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Sep 1 | Sep 3 | M · derivative | 1,740 | $0.00 | $0 | 3,481 | No | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Sep 1 | Sep 3 | M · derivative | 1,611 | $0.00 | $0 | 1,611 | No | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Sep 1 | Sep 3 | M · derivative | 2,477 | $0.00 | $0 | not reported | No | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Jul 15 | Sep 3 | A | 279 | $33.50 | $9,347 | 27,697 | Yes | Form 4 |
| Quart Barry D | Aug 19 | Aug 21 | G | 2,600 | $0.00 | $0 | 12,745 | No | Form 4 |
| Levy Richard S | Aug 1 | Aug 4 | M | 403 | not reported | not reported | 22,359 | No | Form 4 |
| Levy Richard S | Aug 1 | Aug 4 | A · derivative | 403 | $0.00 | $0 | 403 | No | Form 4 |
| Levy Richard S | Aug 1 | Aug 4 | M · derivative | 403 | $0.00 | $0 | not reported | No | Form 4 |
| Cole G Bradley | Jul 29 | Jul 31 | S | 3,673 | $81.43 | Sale −$299,092 | 11,672 | No | Form 4 |
| Cole G Bradley | Jul 29 | Jul 31 | G | 4,500 | $0.00 | $0 | 7,172 | No | Form 4 |
| Malkani Dhiraj HCHIEF STRATEGY OFFICER | Jul 1 | Jul 6 | A · derivative | 82,600 | $62.88 | $5,193,888 | not reported | No | Form 4 |
| Malkani Dhiraj HCHIEF STRATEGY OFFICER | Jul 1 | Jul 6 | A · derivative | 14,000 | $0.00 | $0 | not reported | No | Form 4 |
| Malkani Dhiraj HCHIEF STRATEGY OFFICER | Jul 1 | Jul 6 | A · derivative | 2,119 | $62.88 | $133,243 | not reported | No | Form 4 |
| Malkani Dhiraj HCHIEF STRATEGY OFFICER | Jul 1 | Jul 6 | A · derivative | 2,188 | $62.88 | $137,581 | not reported | No | Form 4 |
| Malkani Dhiraj HCHIEF STRATEGY OFFICER | Jul 1 | Jul 6 | A · derivative | 1,245 | $0.00 | $0 | not reported | No | Form 4 |
| Malkani Dhiraj HCHIEF STRATEGY OFFICER | Jul 1 | Jul 6 | A · derivative | 1,307 | $0.00 | $0 | not reported | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Jun 1 | Jun 2 | C | 900,000 | not reported | not reported | 951,794 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Jun 1 | Jun 2 | C · derivative | 900,000 | $0.00 | $0 | 626,160 | No | Form 4 |
| Baker Julian | May 29 | Jun 2 | A | 6,078 | $0.00 | $0 | 143,277 | No | Form 4 |
| Baker Julian | May 29 | Jun 2 | A | 6,078 | $0.00 | $0 | 2,744,894 | No | Form 4 |
| Baker Julian | May 29 | Jun 2 | A · derivative | 36,474 | $48.38 | $1,764,612 | 36,474 | No | Form 4 |
| Baker Julian | May 29 | Jun 2 | A · derivative | 36,474 | $48.38 | $1,764,612 | 36,474 | No | Form 4 |
| Popovits Kimberly J | May 29 | Jun 2 | M | 2,799 | not reported | not reported | 15,345 | No | Form 4 |
| Popovits Kimberly J | May 29 | Jun 2 | A · derivative | 12,158 | $48.38 | $588,204 | 12,158 | No | Form 4 |
| Popovits Kimberly J | May 29 | Jun 2 | A · derivative | 2,026 | $0.00 | $0 | 2,026 | No | Form 4 |
| Popovits Kimberly J | May 29 | Jun 2 | M · derivative | 2,799 | $0.00 | $0 | not reported | No | Form 4 |
| Cole G Bradley | May 29 | Jun 2 | M | 2,799 | not reported | not reported | 15,345 | No | Form 4 |
| Cole G Bradley | May 29 | Jun 2 | A · derivative | 12,158 | $48.38 | $588,204 | 12,158 | No | Form 4 |
| Cole G Bradley | May 29 | Jun 2 | A · derivative | 2,026 | $0.00 | $0 | 2,026 | No | Form 4 |
| Cole G Bradley | May 29 | Jun 2 | M · derivative | 2,799 | $0.00 | $0 | not reported | No | Form 4 |
| Quart Barry D | May 29 | Jun 2 | M | 2,799 | not reported | not reported | 15,345 | No | Form 4 |
| Quart Barry D | May 29 | Jun 2 | A · derivative | 12,158 | $48.38 | $588,204 | 12,185 | No | Form 4 |
| Quart Barry D | May 29 | Jun 2 | A · derivative | 2,026 | $0.00 | $0 | 2,026 | No | Form 4 |
| Quart Barry D | May 29 | Jun 2 | M · derivative | 2,799 | $0.00 | $0 | not reported | No | Form 4 |
| Malley Thomas | May 29 | Jun 2 | M | 2,799 | not reported | not reported | 15,345 | No | Form 4 |
| Malley Thomas | May 29 | Jun 2 | A · derivative | 12,158 | $48.38 | $588,204 | 12,158 | No | Form 4 |
| Malley Thomas | May 29 | Jun 2 | A · derivative | 2,026 | $0.00 | $0 | 2,026 | No | Form 4 |
| Malley Thomas | May 29 | Jun 2 | M · derivative | 2,799 | $0.00 | $0 | not reported | No | Form 4 |
| Levy Richard S | May 29 | Jun 2 | M | 2,799 | not reported | not reported | 21,956 | No | Form 4 |
| Levy Richard S | May 29 | Jun 2 | A · derivative | 12,158 | $48.38 | $588,204 | 12,158 | No | Form 4 |
| Levy Richard S | May 29 | Jun 2 | A · derivative | 2,026 | $0.00 | $0 | 2,026 | No | Form 4 |
| Levy Richard S | May 29 | Jun 2 | M · derivative | 2,799 | $0.00 | $0 | not reported | No | Form 4 |
| McCain Tracey L | May 29 | Jun 2 | M | 2,799 | not reported | not reported | 15,345 | No | Form 4 |
| McCain Tracey L | May 29 | Jun 2 | A · derivative | 12,158 | $48.38 | $588,204 | 12,158 | No | Form 4 |
| McCain Tracey L | May 29 | Jun 2 | A · derivative | 2,026 | $0.00 | $0 | 2,026 | No | Form 4 |
| McCain Tracey L | May 29 | Jun 2 | M · derivative | 2,799 | $0.00 | $0 | not reported | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | May 1 | May 5 | M | 58,424 | $10.36 | $605,273 | 124,047 | Yes | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | May 1 | May 5 | S | 37,327 | $53.52 | Sale −$1,997,741 | 86,720 | Yes | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | May 1 | May 5 | S | 21,097 | $54.04 | Sale −$1,140,082 | 65,623 | Yes | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | May 1 | May 5 | M · derivative | 58,424 | $10.36 | $605,273 | 29,670 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | May 1 | May 1 | M | 48,565 | $30.93 | $1,502,115 | 48,565 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | May 1 | May 1 | S | 48,565 | $54.02 | Sale −$2,623,481 | not reported | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | May 1 | May 1 | M · derivative | 48,565 | $30.93 | $1,502,115 | not reported | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 30 | Apr 30 | M | 2,141 | $30.93 | $66,221 | 2,141 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 30 | Apr 30 | S | 2,141 | $54.01 | Sale −$115,635 | not reported | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 30 | Apr 30 | M · derivative | 2,141 | $30.93 | $66,221 | 48,565 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 29 | Apr 30 | M | 22,544 | $30.93 | $697,286 | 22,544 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 29 | Apr 30 | S | 22,544 | $54.01 | Sale −$1,217,601 | not reported | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 29 | Apr 30 | M · derivative | 22,544 | $30.93 | $697,286 | 50,706 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 28 | Apr 30 | M | 431,904 | $10.36 | $4,474,525 | 431,904 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 28 | Apr 30 | M | 51,750 | $30.93 | $1,600,628 | 483,654 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 28 | Apr 30 | S | 74,635 | $50.43 | Sale −$3,763,843 | 409,019 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 28 | Apr 30 | S | 113,673 | $51.47 | Sale −$5,850,749 | 295,346 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 28 | Apr 30 | S | 243,596 | $52.02 | Sale −$12,671,864 | 51,750 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 28 | Apr 30 | S | 51,750 | $54.02 | Sale −$2,795,535 | not reported | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 28 | Apr 30 | M · derivative | 431,904 | $10.36 | $4,474,525 | not reported | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 28 | Apr 30 | M · derivative | 51,750 | $30.93 | $1,600,628 | 73,250 | Yes | Form 4 |
| Quart Barry D | Apr 28 | Apr 29 | M | 13,099 | $14.33 | $187,709 | 25,645 | Yes | Form 4 |
| Quart Barry D | Apr 28 | Apr 29 | S | 13,099 | $50.10 | Sale −$656,260 | 12,546 | Yes | Form 4 |
| Quart Barry D | Apr 28 | Apr 29 | M · derivative | 13,099 | $14.33 | $187,709 | 13,237 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Apr 9 | Apr 13 | S | 6,625 | $46.69 | Sale −$309,321 | 27,418 | Yes | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Apr 9 | Apr 13 | S | 1,703 | $46.69 | Sale −$79,513 | 12,029 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Apr 7 | Apr 8 | M | 3,932 | $1.00 | $3,932 | 35,709 | No | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Apr 7 | Apr 8 | F | 1,666 | $48.94 | $81,534 | 34,043 | No | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Apr 7 | Apr 8 | M · derivative | 3,932 | $0.00 | $0 | not reported | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 7 | Apr 8 | M | 9,991 | not reported | not reported | 81,005 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 7 | Apr 8 | F | 4,831 | $48.94 | $236,429 | 76,174 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 7 | Apr 8 | M · derivative | 9,991 | $0.00 | $0 | not reported | Yes | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Apr 7 | Apr 8 | M | 2,497 | not reported | not reported | 66,831 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Apr 7 | Apr 8 | F | 1,208 | $48.94 | $59,120 | 65,623 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Apr 7 | Apr 8 | M · derivative | 2,497 | $0.00 | $0 | not reported | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Apr 7 | Apr 8 | M | 2,694 | not reported | not reported | 17,457 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Apr 7 | Apr 8 | F | 1,303 | $48.94 | $63,769 | 16,154 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Apr 7 | Apr 8 | M · derivative | 2,694 | $0.00 | $0 | not reported | No | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Apr 7 | Apr 8 | M | 2,477 | not reported | not reported | 14,506 | Yes | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Apr 7 | Apr 8 | F | 774 | $48.94 | $37,880 | 13,732 | Yes | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Apr 7 | Apr 8 | M · derivative | 2,477 | $0.00 | $0 | not reported | Yes | Form 4 |
| Tessari EbenCHIEF STRATEGY OFFICER | Apr 7 | Apr 8 | M | 2,726 | not reported | not reported | 23,976 | No | Form 4 |
| Tessari EbenCHIEF STRATEGY OFFICER | Apr 7 | Apr 8 | F | 846 | $48.94 | $41,403 | 23,130 | No | Form 4 |
| Tessari EbenCHIEF STRATEGY OFFICER | Apr 7 | Apr 8 | M · derivative | 2,726 | $0.00 | $0 | not reported | No | Form 4 |
| Quart Barry D | Apr 6 | Apr 8 | M | 6,901 | $14.33 | $98,891 | 19,447 | Yes | Form 4 |
| Quart Barry D | Apr 6 | Apr 8 | S | 6,901 | $50.00 | Sale −$345,050 | 12,546 | Yes | Form 4 |
| Quart Barry D | Apr 6 | Apr 8 | M · derivative | 6,901 | $14.33 | $98,891 | 26,336 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 6 | Apr 8 | M | 7,278 | $10.36 | $75,400 | 7,278 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 6 | Apr 8 | S | 7,278 | $50.01 | Sale −$363,973 | not reported | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 6 | Apr 8 | M · derivative | 7,278 | $10.36 | $75,400 | 431,904 | Yes | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Apr 6 | Apr 8 | S | 2,367 | $48.58 | Sale −$114,989 | 12,029 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Apr 1 | Apr 3 | M | 7,564 | not reported | not reported | 34,982 | No | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Apr 1 | Apr 3 | F | 3,205 | $48.13 | $154,257 | 31,777 | No | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Apr 1 | Apr 3 | A · derivative | 14,600 | $48.13 | $702,698 | 14,600 | No | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Apr 1 | Apr 3 | A · derivative | 3,650 | $0.00 | $0 | 3,650 | No | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Apr 1 | Apr 3 | A · derivative | 7,300 | $0.00 | $0 | 7,300 | No | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Apr 1 | Apr 3 | M · derivative | 2,558 | $0.00 | $0 | 2,557 | No | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Apr 1 | Apr 3 | M · derivative | 2,362 | $0.00 | $0 | 4,725 | No | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Apr 1 | Apr 3 | M · derivative | 2,644 | $0.00 | $0 | 7,931 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 1 | Apr 3 | M | 21,327 | not reported | not reported | 81,327 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 1 | Apr 3 | F | 10,313 | $48.13 | $496,365 | 71,014 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 1 | Apr 3 | A · derivative | 120,150 | $48.13 | $5,782,820 | 120,150 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 1 | Apr 3 | A · derivative | 30,050 | $0.00 | $0 | 30,050 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 1 | Apr 3 | A · derivative | 60,100 | $0.00 | $0 | 60,100 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 1 | Apr 3 | M · derivative | 6,481 | $0.00 | $0 | 6,481 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 1 | Apr 3 | M · derivative | 6,237 | $0.00 | $0 | 12,475 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Apr 1 | Apr 3 | M · derivative | 8,609 | $0.00 | $0 | 25,826 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Apr 1 | Apr 3 | M | 5,831 | not reported | not reported | 67,155 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Apr 1 | Apr 3 | F | 2,821 | $48.13 | $135,775 | 64,334 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Apr 1 | Apr 3 | A · derivative | 26,750 | $48.13 | $1,287,478 | 26,750 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Apr 1 | Apr 3 | A · derivative | 6,700 | $0.00 | $0 | 6,700 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Apr 1 | Apr 3 | A · derivative | 13,400 | $0.00 | $0 | 13,400 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Apr 1 | Apr 3 | M · derivative | 1,624 | $0.00 | $0 | 1,624 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Apr 1 | Apr 3 | M · derivative | 1,750 | $0.00 | $0 | 3,500 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Apr 1 | Apr 3 | M · derivative | 2,457 | $0.00 | $0 | 7,371 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Apr 1 | Apr 3 | M | 5,187 | not reported | not reported | 17,273 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Apr 1 | Apr 3 | F | 2,510 | $48.13 | $120,806 | 14,763 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Apr 1 | Apr 3 | A · derivative | 31,150 | $48.13 | $1,499,250 | 31,150 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Apr 1 | Apr 3 | A · derivative | 7,800 | $0.00 | $0 | 7,800 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Apr 1 | Apr 3 | A · derivative | 15,600 | $0.00 | $0 | 15,600 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Apr 1 | Apr 3 | M · derivative | 1,750 | $0.00 | $0 | 1,750 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Apr 1 | Apr 3 | M · derivative | 1,591 | $0.00 | $0 | 3,182 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Apr 1 | Apr 3 | M · derivative | 1,846 | $0.00 | $0 | 5,536 | No | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Apr 1 | Apr 3 | M | 5,808 | not reported | not reported | 16,102 | No | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Apr 1 | Apr 3 | F | 1,706 | $48.13 | $82,110 | 14,396 | No | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Apr 1 | Apr 3 | A · derivative | 36,950 | $48.13 | $1,778,404 | 36,950 | No | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Apr 1 | Apr 3 | A · derivative | 9,250 | $0.00 | $0 | 9,250 | No | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Apr 1 | Apr 3 | A · derivative | 18,500 | $0.00 | $0 | 18,500 | No | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Apr 1 | Apr 3 | M · derivative | 1,611 | $0.00 | $0 | 1,161 | No | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Apr 1 | Apr 3 | M · derivative | 1,740 | $0.00 | $0 | 3,481 | No | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Apr 1 | Apr 3 | M · derivative | 2,457 | $0.00 | $0 | 7,371 | No | Form 4 |
| Tessari EbenCHIEF STRATEGY OFFICER | Apr 1 | Apr 3 | M | 5,975 | not reported | not reported | 23,006 | No | Form 4 |
| Tessari EbenCHIEF STRATEGY OFFICER | Apr 1 | Apr 3 | F | 1,756 | $48.13 | $84,516 | 21,250 | No | Form 4 |
| Tessari EbenCHIEF STRATEGY OFFICER | Apr 1 | Apr 3 | A · derivative | 33,200 | $48.13 | $1,597,916 | 33,200 | No | Form 4 |
| Tessari EbenCHIEF STRATEGY OFFICER | Apr 1 | Apr 3 | A · derivative | 8,300 | $0.00 | $0 | 8,300 | No | Form 4 |
| Tessari EbenCHIEF STRATEGY OFFICER | Apr 1 | Apr 3 | A · derivative | 16,600 | $0.00 | $0 | 16,600 | No | Form 4 |
| Tessari EbenCHIEF STRATEGY OFFICER | Apr 1 | Apr 3 | M · derivative | 1,773 | $0.00 | $0 | 1,772 | No | Form 4 |
| Tessari EbenCHIEF STRATEGY OFFICER | Apr 1 | Apr 3 | M · derivative | 1,745 | $0.00 | $0 | 3,490 | No | Form 4 |
| Tessari EbenCHIEF STRATEGY OFFICER | Apr 1 | Apr 3 | M · derivative | 2,457 | $0.00 | $0 | 7,371 | No | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Jan 15 | Apr 3 | A | 372 | $24.16 | $8,988 | 27,418 | No | Form 4 |
| Moat RossCHIEF OPERATING OFFICER | Jan 15 | Apr 3 | A | 879 | $24.16 | $21,237 | 10,294 | No | Form 4 |
| Tessari EbenCHIEF STRATEGY OFFICER | Jan 15 | Apr 3 | A | 365 | $24.16 | $8,818 | 17,031 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Mar 9 | Mar 11 | M | 2,036 | $22.89 | $46,604 | 14,122 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Mar 9 | Mar 11 | M | 10,513 | $17.76 | $186,711 | 24,635 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Mar 9 | Mar 11 | M | 13,813 | $18.06 | $249,463 | 38,448 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Mar 9 | Mar 11 | M | 10,360 | $26.74 | $277,026 | 48,808 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Mar 9 | Mar 11 | S | 17,981 | $45.58 | Sale −$819,574 | 30,827 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Mar 9 | Mar 11 | S | 18,741 | $46.24 | Sale −$866,584 | 12,086 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Mar 9 | Mar 11 | M · derivative | 2,036 | $22.89 | $46,604 | not reported | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Mar 9 | Mar 11 | M · derivative | 10,513 | $17.76 | $186,711 | 18,396 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Mar 9 | Mar 11 | M · derivative | 13,813 | $18.06 | $249,463 | 19,337 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Mar 9 | Mar 11 | M · derivative | 10,360 | $26.74 | $277,026 | 22,790 | Yes | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Mar 2 | Mar 4 | M | 40,000 | $10.36 | $414,400 | 101,324 | Yes | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Mar 2 | Mar 4 | S | 12,063 | $44.20 | Sale −$533,185 | 89,261 | Yes | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Mar 2 | Mar 4 | S | 22,223 | $44.88 | Sale −$997,368 | 67,038 | Yes | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Mar 2 | Mar 4 | S | 5,714 | $45.92 | Sale −$262,387 | 61,324 | Yes | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Mar 2 | Mar 4 | M · derivative | 40,000 | $10.36 | $414,400 | 58,424 | Yes | Form 4 |
| Quart Barry D | Feb 12 | Feb 12 | M | 2,690 | $15.47 | $41,614 | 15,236 | Yes | Form 4 |
| Quart Barry D | Feb 12 | Feb 12 | S | 2,690 | $45.00 | Sale −$121,050 | 12,546 | Yes | Form 4 |
| Quart Barry D | Feb 12 | Feb 12 | M · derivative | 2,690 | $15.47 | $41,614 | not reported | Yes | Form 4 |
| Quart Barry D | Feb 10 | Feb 12 | M | 110 | $15.47 | $1,702 | 12,656 | Yes | Form 4 |
| Quart Barry D | Feb 10 | Feb 12 | S | 110 | $45.00 | Sale −$4,950 | 12,546 | Yes | Form 4 |
| Quart Barry D | Feb 10 | Feb 12 | M · derivative | 110 | $15.47 | $1,702 | 2,690 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Feb 9 | Feb 11 | M | 8,374 | $12.97 | $108,611 | 27,460 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Feb 9 | Feb 11 | M | 2,471 | $16.90 | $41,760 | 29,931 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Feb 9 | Feb 11 | S | 9,114 | $42.85 | Sale −$390,535 | 20,817 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Feb 9 | Feb 11 | S | 8,731 | $43.72 | Sale −$381,719 | 12,086 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Feb 9 | Feb 11 | M · derivative | 8,374 | $12.97 | $108,611 | not reported | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Feb 9 | Feb 11 | M · derivative | 2,471 | $16.90 | $41,760 | not reported | Yes | Form 4 |
| Quart Barry D | Feb 4 | Feb 4 | M | 2,602 | $15.47 | $40,253 | 15,148 | Yes | Form 4 |
| Quart Barry D | Feb 4 | Feb 4 | S | 2,602 | $45.02 | Sale −$117,142 | 12,546 | Yes | Form 4 |
| Quart Barry D | Feb 4 | Feb 4 | M · derivative | 2,602 | $15.47 | $40,253 | 2,800 | Yes | Form 4 |
| Quart Barry D | Feb 3 | Feb 4 | M | 12,528 | $15.47 | $193,808 | 25,074 | Yes | Form 4 |
| Quart Barry D | Feb 3 | Feb 4 | S | 12,528 | $45.27 | Sale −$567,143 | 12,546 | Yes | Form 4 |
| Quart Barry D | Feb 3 | Feb 4 | M · derivative | 12,528 | $15.47 | $193,808 | 5,402 | Yes | Form 4 |
| Quart Barry D | Feb 2 | Feb 4 | M | 830 | $15.47 | $12,840 | 13,376 | Yes | Form 4 |
| Quart Barry D | Feb 2 | Feb 4 | S | 830 | $45.00 | Sale −$37,350 | 12,546 | Yes | Form 4 |
| Quart Barry D | Feb 2 | Feb 4 | M · derivative | 830 | $15.47 | $12,840 | 17,930 | Yes | Form 4 |
| Levy Richard S | Feb 1 | Feb 4 | M | 683 | not reported | not reported | 19,157 | No | Form 4 |
| Levy Richard S | Feb 1 | Feb 4 | A · derivative | 683 | $0.00 | $0 | 683 | No | Form 4 |
| Levy Richard S | Feb 1 | Feb 4 | M · derivative | 683 | $0.00 | $0 | not reported | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Jan 8 | Jan 9 | S | 12,000 | $41.89 | Sale −$502,680 | 19,086 | Yes | Form 4 |
| Quart Barry D | Dec 15, 2025 | Dec 17, 2025 | M | 20,129 | $10.36 | $208,536 | 32,675 | Yes | Form 4 |
| Quart Barry D | Dec 15, 2025 | Dec 17, 2025 | S | 20,129 | $41.51 | Sale −$835,555 | 12,546 | Yes | Form 4 |
| Quart Barry D | Dec 15, 2025 | Dec 17, 2025 | M · derivative | 20,129 | $10.36 | $208,536 | not reported | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Dec 15, 2025 | Dec 17, 2025 | M | 6,000 | $8.83 | $52,980 | 28,714 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Dec 15, 2025 | Dec 17, 2025 | S | 12,048 | $41.56 | Sale −$500,715 | 16,666 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Dec 15, 2025 | Dec 17, 2025 | M · derivative | 6,000 | $8.83 | $52,980 | not reported | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Dec 8, 2025 | Dec 10, 2025 | M | 16,164 | $11.10 | $179,420 | 47,250 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Dec 8, 2025 | Dec 10, 2025 | M | 16,165 | $11.97 | $193,495 | 63,415 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Dec 8, 2025 | Dec 10, 2025 | M | 10,512 | $10.76 | $113,109 | 73,927 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Dec 8, 2025 | Dec 10, 2025 | S | 42,841 | $41.49 | Sale −$1,777,473 | 31,086 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Dec 8, 2025 | Dec 10, 2025 | M · derivative | 16,164 | $11.10 | $179,420 | 5,388 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Dec 8, 2025 | Dec 10, 2025 | M · derivative | 16,165 | $11.97 | $193,495 | 12,123 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Dec 8, 2025 | Dec 10, 2025 | M · derivative | 10,512 | $10.76 | $113,109 | 14,016 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Nov 26, 2025 | Dec 1, 2025 | M | 200 | $22.89 | $4,578 | 22,914 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Nov 26, 2025 | Dec 1, 2025 | S | 200 | $42.89 | Sale −$8,578 | 22,714 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Nov 26, 2025 | Dec 1, 2025 | M · derivative | 200 | $22.89 | $4,578 | 46,938 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Nov 17, 2025 | Nov 19, 2025 | M | 6,500 | $8.83 | $57,395 | 35,184 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Nov 17, 2025 | Nov 19, 2025 | S | 645 | $40.08 | Sale −$25,852 | 34,539 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Nov 17, 2025 | Nov 19, 2025 | S | 11,825 | $41.30 | Sale −$488,373 | 22,714 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Nov 17, 2025 | Nov 19, 2025 | M · derivative | 6,500 | $8.83 | $57,395 | 6,000 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Nov 13, 2025 | Nov 14, 2025 | G | 60,000 | $0.00 | $0 | 51,794 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Nov 13, 2025 | Nov 14, 2025 | G | 60,000 | $0.00 | $0 | 60,000 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Nov 12, 2025 | Nov 14, 2025 | G | 111,794 | $0.00 | $0 | not reported | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Nov 12, 2025 | Nov 14, 2025 | G | 111,794 | $0.00 | $0 | 111,794 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Nov 12, 2025 | Nov 14, 2025 | M | 19,900 | $30.93 | $615,507 | 50,986 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Nov 12, 2025 | Nov 14, 2025 | S | 19,900 | $40.94 | Sale −$814,706 | 31,086 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Nov 12, 2025 | Nov 14, 2025 | M · derivative | 19,900 | $30.93 | $615,507 | not reported | Yes | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Oct 31, 2025 | Nov 4, 2025 | M | 36,542 | $3.80 | $138,860 | 97,866 | Yes | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Oct 31, 2025 | Nov 4, 2025 | M | 46,000 | $8.83 | $406,180 | 143,866 | Yes | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Oct 31, 2025 | Nov 4, 2025 | S | 82,542 | $37.14 | Sale −$3,065,610 | 61,324 | Yes | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Oct 31, 2025 | Nov 4, 2025 | M · derivative | 36,542 | $3.80 | $138,860 | not reported | Yes | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Oct 31, 2025 | Nov 4, 2025 | M · derivative | 46,000 | $8.83 | $406,180 | not reported | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Oct 28, 2025 | Oct 30, 2025 | M | 100 | $30.93 | $3,093 | 31,186 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Oct 28, 2025 | Oct 30, 2025 | S | 100 | $41.00 | Sale −$4,100 | 31,086 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Oct 28, 2025 | Oct 30, 2025 | M · derivative | 100 | $30.93 | $3,093 | 19,900 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Oct 22, 2025 | Oct 22, 2025 | M | 97,390 | $3.80 | $370,082 | 209,184 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Oct 22, 2025 | Oct 22, 2025 | S | 97,390 | $38.83 | Sale −$3,781,654 | 111,794 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Oct 22, 2025 | Oct 22, 2025 | M · derivative | 97,390 | $3.80 | $370,082 | not reported | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Oct 21, 2025 | Oct 22, 2025 | M | 39,331 | $3.80 | $149,458 | 151,125 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Oct 21, 2025 | Oct 22, 2025 | S | 39,331 | $38.77 | Sale −$1,524,863 | 111,794 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Oct 21, 2025 | Oct 22, 2025 | M · derivative | 39,331 | $3.80 | $149,458 | 97,390 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Oct 20, 2025 | Oct 22, 2025 | M | 791 | $15.50 | $12,261 | 38,892 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Oct 20, 2025 | Oct 22, 2025 | M | 6,195 | $12.97 | $80,349 | 45,087 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Oct 20, 2025 | Oct 22, 2025 | M | 9,831 | $11.10 | $109,124 | 54,918 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Oct 20, 2025 | Oct 22, 2025 | M | 9,831 | $11.97 | $117,677 | 64,749 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Oct 20, 2025 | Oct 22, 2025 | M | 12,787 | $10.76 | $137,588 | 77,536 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Oct 20, 2025 | Oct 22, 2025 | S | 37,255 | $38.72 | Sale −$1,442,514 | 40,281 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Oct 20, 2025 | Oct 22, 2025 | S | 13,235 | $39.31 | Sale −$520,268 | 27,046 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Oct 20, 2025 | Oct 22, 2025 | M · derivative | 791 | $15.50 | $12,261 | not reported | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Oct 20, 2025 | Oct 22, 2025 | M · derivative | 6,195 | $12.97 | $80,349 | not reported | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Oct 20, 2025 | Oct 22, 2025 | M · derivative | 9,831 | $11.10 | $109,124 | not reported | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Oct 20, 2025 | Oct 22, 2025 | M · derivative | 9,831 | $11.97 | $117,677 | not reported | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Oct 20, 2025 | Oct 22, 2025 | M · derivative | 12,787 | $10.76 | $137,588 | not reported | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Oct 20, 2025 | Oct 22, 2025 | M | 121,248 | $3.80 | $460,742 | 233,042 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Oct 20, 2025 | Oct 22, 2025 | S | 98,934 | $38.81 | Sale −$3,839,629 | 134,108 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Oct 20, 2025 | Oct 22, 2025 | S | 22,314 | $39.32 | Sale −$877,386 | 111,794 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Oct 20, 2025 | Oct 22, 2025 | M · derivative | 121,248 | $3.80 | $460,742 | 136,721 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Oct 14, 2025 | Oct 16, 2025 | M | 6,500 | $8.83 | $57,395 | 41,052 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Oct 14, 2025 | Oct 16, 2025 | S | 11,815 | $37.65 | Sale −$444,835 | 29,237 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Oct 14, 2025 | Oct 16, 2025 | S | 553 | $37.99 | Sale −$21,008 | 28,684 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Oct 14, 2025 | Oct 16, 2025 | M · derivative | 6,500 | $8.83 | $57,395 | 12,500 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Oct 4, 2025 | Oct 8, 2025 | M | 175 | not reported | not reported | 38,186 | No | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Oct 4, 2025 | Oct 8, 2025 | F | 85 | $38.49 | $3,272 | 38,101 | No | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Oct 4, 2025 | Oct 8, 2025 | M · derivative | 175 | $0.00 | $0 | not reported | No | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 29, 2025 | Oct 1, 2025 | M | 42,000 | $17.92 | $752,640 | 76,552 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 29, 2025 | Oct 1, 2025 | S | 42,000 | $38.33 | Sale −$1,609,860 | 34,552 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 29, 2025 | Oct 1, 2025 | M · derivative | 42,000 | $17.92 | $752,640 | not reported | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 15, 2025 | Sep 17, 2025 | M | 6,500 | $8.83 | $57,395 | 50,952 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 15, 2025 | Sep 17, 2025 | S | 16,044 | $36.45 | Sale −$584,804 | 34,908 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 15, 2025 | Sep 17, 2025 | S | 356 | $37.00 | Sale −$13,172 | 34,552 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 15, 2025 | Sep 17, 2025 | M · derivative | 6,500 | $8.83 | $57,395 | 19,000 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 5, 2025 | Sep 8, 2025 | M | 13,389 | $15.52 | $207,797 | 57,841 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 5, 2025 | Sep 8, 2025 | S | 13,389 | $35.66 | Sale −$477,452 | 44,452 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 5, 2025 | Sep 8, 2025 | M · derivative | 13,389 | $15.52 | $207,797 | not reported | Yes | Form 4 |
| Moat RossCHIEF CORP. & COMM. OFFICER | Sep 4, 2025 | Sep 8, 2025 | S | 3,523 | $35.31 | Sale −$124,397 | 9,415 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 4, 2025 | Sep 8, 2025 | M | 38,725 | $15.50 | $600,238 | 83,177 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 4, 2025 | Sep 8, 2025 | M | 46,546 | $15.52 | $722,394 | 129,723 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 4, 2025 | Sep 8, 2025 | S | 85,271 | $35.52 | Sale −$3,028,826 | 44,452 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 4, 2025 | Sep 8, 2025 | M · derivative | 38,725 | $15.50 | $600,238 | 6,249 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 4, 2025 | Sep 8, 2025 | M · derivative | 46,546 | $15.52 | $722,394 | 13,389 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 3, 2025 | Sep 3, 2025 | M | 11,000 | $17.92 | $197,120 | 49,011 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 3, 2025 | Sep 3, 2025 | S | 11,000 | $34.84 | Sale −$383,240 | 38,011 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 3, 2025 | Sep 3, 2025 | M · derivative | 11,000 | $17.92 | $197,120 | not reported | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 3, 2025 | Sep 3, 2025 | M | 65 | $15.52 | $1,009 | 44,517 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 3, 2025 | Sep 3, 2025 | M | 15,026 | $15.50 | $232,903 | 59,543 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 3, 2025 | Sep 3, 2025 | S | 15,091 | $35.50 | Sale −$535,731 | 44,452 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 3, 2025 | Sep 3, 2025 | M · derivative | 65 | $15.52 | $1,009 | 59,935 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 3, 2025 | Sep 3, 2025 | M · derivative | 15,026 | $15.50 | $232,903 | 44,974 | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 2, 2025 | Sep 3, 2025 | M | 6,569 | not reported | not reported | 114,971 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 2, 2025 | Sep 3, 2025 | F | 3,177 | $34.28 | $108,908 | 111,794 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 2, 2025 | Sep 3, 2025 | M · derivative | 6,569 | $0.00 | $0 | not reported | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 2, 2025 | Sep 3, 2025 | M | 1,861 | not reported | not reported | 31,986 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 2, 2025 | Sep 3, 2025 | F | 900 | $34.28 | $30,852 | 31,086 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 2, 2025 | Sep 3, 2025 | M · derivative | 1,861 | $0.00 | $0 | not reported | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 2, 2025 | Sep 3, 2025 | M | 1,725 | not reported | not reported | 62,159 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 2, 2025 | Sep 3, 2025 | F | 835 | $34.28 | $28,624 | 61,324 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 2, 2025 | Sep 3, 2025 | M · derivative | 1,725 | $0.00 | $0 | not reported | No | Form 4 |
| Moat RossCHIEF CORP. & COMM. OFFICER | Sep 2, 2025 | Sep 3, 2025 | M | 994 | not reported | not reported | 13,419 | No | Form 4 |
| Moat RossCHIEF CORP. & COMM. OFFICER | Sep 2, 2025 | Sep 3, 2025 | F | 481 | $34.28 | $16,489 | 12,938 | No | Form 4 |
| Moat RossCHIEF CORP. & COMM. OFFICER | Sep 2, 2025 | Sep 3, 2025 | M · derivative | 994 | $0.00 | $0 | not reported | No | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 2, 2025 | Sep 3, 2025 | M | 774 | not reported | not reported | 38,386 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 2, 2025 | Sep 3, 2025 | F | 375 | $34.28 | $12,855 | 38,011 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 2, 2025 | Sep 3, 2025 | M · derivative | 774 | $0.00 | $0 | not reported | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 2, 2025 | Sep 3, 2025 | M | 1,964 | not reported | not reported | 45,402 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 2, 2025 | Sep 3, 2025 | F | 950 | $34.28 | $32,566 | 44,452 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 2, 2025 | Sep 3, 2025 | M · derivative | 1,964 | $0.00 | $0 | not reported | Yes | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1, 2025 | Sep 3, 2025 | M | 6,238 | not reported | not reported | 102,912 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1, 2025 | Sep 3, 2025 | M | 6,481 | not reported | not reported | 109,393 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1, 2025 | Sep 3, 2025 | M | 9,992 | not reported | not reported | 119,385 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1, 2025 | Sep 3, 2025 | F | 10,983 | $33.49 | $367,821 | 108,402 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1, 2025 | Sep 3, 2025 | A · derivative | 34,435 | $0.00 | $0 | 34,435 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1, 2025 | Sep 3, 2025 | A · derivative | 137,638 | $33.49 | $4,609,497 | 137,638 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1, 2025 | Sep 3, 2025 | M · derivative | 6,238 | $0.00 | $0 | 18,712 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1, 2025 | Sep 3, 2025 | M · derivative | 6,481 | $0.00 | $0 | 12,962 | No | Form 4 |
| Patel Sanj KCHAIRMAN & CEO | Sep 1, 2025 | Sep 3, 2025 | M · derivative | 9,992 | $0.00 | $0 | 9,991 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 1, 2025 | Sep 3, 2025 | M | 1,592 | not reported | not reported | 28,601 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 1, 2025 | Sep 3, 2025 | M | 1,750 | not reported | not reported | 30,351 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 1, 2025 | Sep 3, 2025 | M | 2,694 | not reported | not reported | 33,045 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 1, 2025 | Sep 3, 2025 | F | 2,920 | $33.49 | $97,791 | 30,125 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 1, 2025 | Sep 3, 2025 | A · derivative | 12,275 | $0.00 | $0 | 12,275 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 1, 2025 | Sep 3, 2025 | A · derivative | 39,363 | $33.49 | $1,318,267 | 39,363 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 1, 2025 | Sep 3, 2025 | M · derivative | 1,592 | $0.00 | $0 | 4,773 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 1, 2025 | Sep 3, 2025 | M · derivative | 1,750 | $0.00 | $0 | 3,500 | No | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Sep 1, 2025 | Sep 3, 2025 | M · derivative | 2,694 | $0.00 | $0 | 2,694 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 1, 2025 | Sep 3, 2025 | M | 1,750 | not reported | not reported | 59,153 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 1, 2025 | Sep 3, 2025 | M | 1,624 | not reported | not reported | 60,777 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 1, 2025 | Sep 3, 2025 | M | 2,498 | not reported | not reported | 63,275 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 1, 2025 | Sep 3, 2025 | F | 2,841 | $33.49 | $95,145 | 60,434 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 1, 2025 | Sep 3, 2025 | A · derivative | 9,828 | $0.00 | $0 | 9,828 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 1, 2025 | Sep 3, 2025 | A · derivative | 39,364 | $33.49 | $1,318,300 | 39,364 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 1, 2025 | Sep 3, 2025 | M · derivative | 1,750 | $0.00 | $0 | 5,250 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 1, 2025 | Sep 3, 2025 | M · derivative | 1,624 | $0.00 | $0 | 3,248 | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Sep 1, 2025 | Sep 3, 2025 | M · derivative | 2,498 | $0.00 | $0 | 2,497 | No | Form 4 |
| Moat RossCHIEF CORP. & COMM. OFFICER | Sep 1, 2025 | Sep 3, 2025 | M | 1,741 | not reported | not reported | 11,156 | No | Form 4 |
| Moat RossCHIEF CORP. & COMM. OFFICER | Sep 1, 2025 | Sep 3, 2025 | M | 1,611 | not reported | not reported | 12,767 | No | Form 4 |
| Moat RossCHIEF CORP. & COMM. OFFICER | Sep 1, 2025 | Sep 3, 2025 | M | 2,477 | not reported | not reported | 15,244 | No | Form 4 |
| Moat RossCHIEF CORP. & COMM. OFFICER | Sep 1, 2025 | Sep 3, 2025 | F | 2,819 | $33.49 | $94,408 | 12,425 | No | Form 4 |
| Moat RossCHIEF CORP. & COMM. OFFICER | Sep 1, 2025 | Sep 3, 2025 | A · derivative | 9,828 | $0.00 | $0 | 9,828 | No | Form 4 |
| Moat RossCHIEF CORP. & COMM. OFFICER | Sep 1, 2025 | Sep 3, 2025 | A · derivative | 39,364 | $33.49 | $1,318,300 | 39,364 | No | Form 4 |
| Moat RossCHIEF CORP. & COMM. OFFICER | Sep 1, 2025 | Sep 3, 2025 | M · derivative | 1,741 | $0.00 | $0 | 5,221 | No | Form 4 |
| Moat RossCHIEF CORP. & COMM. OFFICER | Sep 1, 2025 | Sep 3, 2025 | M · derivative | 1,611 | $0.00 | $0 | 3,222 | No | Form 4 |
| Moat RossCHIEF CORP. & COMM. OFFICER | Sep 1, 2025 | Sep 3, 2025 | M · derivative | 2,477 | $0.00 | $0 | 2,477 | No | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 1, 2025 | Sep 3, 2025 | M | 2,363 | not reported | not reported | 35,404 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 1, 2025 | Sep 3, 2025 | M | 2,557 | not reported | not reported | 37,961 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 1, 2025 | Sep 3, 2025 | M | 3,933 | not reported | not reported | 41,894 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 1, 2025 | Sep 3, 2025 | F | 4,282 | $33.49 | $143,404 | 37,612 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 1, 2025 | Sep 3, 2025 | A · derivative | 10,575 | $0.00 | $0 | 10,575 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 1, 2025 | Sep 3, 2025 | A · derivative | 21,150 | $33.49 | $708,314 | 21,150 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 1, 2025 | Sep 3, 2025 | M · derivative | 2,363 | $0.00 | $0 | 7,087 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 1, 2025 | Sep 3, 2025 | M · derivative | 2,557 | $0.00 | $0 | 5,115 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Sep 1, 2025 | Sep 3, 2025 | M · derivative | 3,933 | $0.00 | $0 | 3,932 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 1, 2025 | Sep 3, 2025 | M | 1,746 | not reported | not reported | 41,961 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 1, 2025 | Sep 3, 2025 | M | 1,773 | not reported | not reported | 43,734 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 1, 2025 | Sep 3, 2025 | M | 2,726 | not reported | not reported | 46,460 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 1, 2025 | Sep 3, 2025 | F | 3,022 | $33.49 | $101,207 | 43,438 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 1, 2025 | Sep 3, 2025 | A · derivative | 9,828 | $0.00 | $0 | 9,828 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 1, 2025 | Sep 3, 2025 | A · derivative | 39,364 | $33.49 | $1,318,300 | 39,364 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 1, 2025 | Sep 3, 2025 | M · derivative | 1,746 | $0.00 | $0 | 5,235 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 1, 2025 | Sep 3, 2025 | M · derivative | 1,773 | $0.00 | $0 | 3,545 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Sep 1, 2025 | Sep 3, 2025 | M · derivative | 2,726 | $0.00 | $0 | 2,726 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Aug 18, 2025 | Aug 20, 2025 | M | 6,500 | $8.83 | $57,395 | 56,415 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Aug 18, 2025 | Aug 20, 2025 | S | 16,100 | $33.77 | Sale −$543,697 | 40,315 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Aug 18, 2025 | Aug 20, 2025 | S | 100 | $34.44 | Sale −$3,444 | 40,215 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Aug 18, 2025 | Aug 20, 2025 | M · derivative | 6,500 | $8.83 | $57,395 | 25,500 | Yes | Form 4 |
| Malley Thomas | Aug 14, 2025 | Aug 14, 2025 | M | 18,760 | $15.47 | $290,217 | 31,306 | No | Form 4 |
| Malley Thomas | Aug 14, 2025 | Aug 14, 2025 | M | 33,237 | $14.33 | $476,286 | 64,543 | No | Form 4 |
| Malley Thomas | Aug 14, 2025 | Aug 14, 2025 | M | 26,236 | $15.19 | $398,525 | 90,779 | No | Form 4 |
| Malley Thomas | Aug 14, 2025 | Aug 14, 2025 | S | 78,233 | $33.09 | Sale −$2,588,730 | 12,546 | No | Form 4 |
| Malley Thomas | Aug 14, 2025 | Aug 14, 2025 | M · derivative | 18,760 | $15.47 | $290,217 | not reported | No | Form 4 |
| Malley Thomas | Aug 14, 2025 | Aug 14, 2025 | M · derivative | 33,237 | $14.33 | $476,286 | not reported | No | Form 4 |
| Malley Thomas | Aug 14, 2025 | Aug 14, 2025 | M · derivative | 26,236 | $15.19 | $398,525 | not reported | No | Form 4 |
| Malley Thomas | Aug 13, 2025 | Aug 14, 2025 | M | 20,129 | $10.36 | $208,536 | 32,675 | No | Form 4 |
| Malley Thomas | Aug 13, 2025 | Aug 14, 2025 | M | 30,000 | $9.88 | $296,400 | 62,675 | No | Form 4 |
| Malley Thomas | Aug 13, 2025 | Aug 14, 2025 | S | 50,129 | $33.32 | Sale −$1,670,298 | 12,546 | No | Form 4 |
| Malley Thomas | Aug 13, 2025 | Aug 14, 2025 | M · derivative | 20,129 | $10.36 | $208,536 | not reported | No | Form 4 |
| Malley Thomas | Aug 13, 2025 | Aug 14, 2025 | M · derivative | 30,000 | $9.88 | $296,400 | not reported | No | Form 4 |
| Malley Thomas | Aug 12, 2025 | Aug 14, 2025 | M | 21,959 | $1.86 | $40,844 | 34,505 | No | Form 4 |
| Malley Thomas | Aug 12, 2025 | Aug 14, 2025 | M | 27,448 | $3.80 | $104,302 | 61,953 | No | Form 4 |
| Malley Thomas | Aug 12, 2025 | Aug 14, 2025 | S | 49,407 | $32.40 | Sale −$1,600,787 | 12,546 | No | Form 4 |
| Malley Thomas | Aug 12, 2025 | Aug 14, 2025 | M · derivative | 21,959 | $1.86 | $40,844 | not reported | No | Form 4 |
| Malley Thomas | Aug 12, 2025 | Aug 14, 2025 | M · derivative | 27,448 | $3.80 | $104,302 | not reported | No | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Aug 6, 2025 | Aug 8, 2025 | M | 29,325 | $3.80 | $111,435 | 86,728 | Yes | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Aug 6, 2025 | Aug 8, 2025 | S | 29,325 | $32.55 | Sale −$954,529 | 57,403 | Yes | Form 4 |
| Paolini John F.CHIEF MEDICAL OFFICER | Aug 6, 2025 | Aug 8, 2025 | M · derivative | 29,325 | $3.80 | $111,435 | 36,542 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Aug 5, 2025 | Aug 7, 2025 | M | 38,928 | $10.36 | $403,294 | 88,843 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Aug 5, 2025 | Aug 7, 2025 | M | 30,444 | $12.97 | $394,859 | 119,287 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Aug 5, 2025 | Aug 7, 2025 | M | 32,710 | $11.10 | $363,081 | 151,997 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Aug 5, 2025 | Aug 7, 2025 | M | 25,896 | $11.97 | $309,975 | 177,893 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Aug 5, 2025 | Aug 7, 2025 | M | 10,636 | $10.76 | $114,443 | 188,529 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Aug 5, 2025 | Aug 7, 2025 | S | 138,064 | $33.20 | Sale −$4,583,725 | 50,465 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Aug 5, 2025 | Aug 7, 2025 | S | 550 | $33.90 | Sale −$18,645 | 49,915 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Aug 5, 2025 | Aug 7, 2025 | M · derivative | 38,928 | $10.36 | $403,294 | not reported | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Aug 5, 2025 | Aug 7, 2025 | M · derivative | 30,444 | $12.97 | $394,859 | 16,694 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Aug 5, 2025 | Aug 7, 2025 | M · derivative | 32,710 | $11.10 | $363,081 | 32,710 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Aug 5, 2025 | Aug 7, 2025 | M · derivative | 25,896 | $11.97 | $309,975 | 39,524 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Aug 5, 2025 | Aug 7, 2025 | M · derivative | 10,636 | $10.76 | $114,443 | 31,908 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Jul 15, 2025 | Aug 7, 2025 | A | 752 | $15.63 | $11,754 | 49,915 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Aug 4, 2025 | Aug 6, 2025 | M | 17,000 | $15.52 | $263,840 | 50,041 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Aug 4, 2025 | Aug 6, 2025 | S | 17,000 | $32.35 | Sale −$549,950 | 33,041 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Aug 4, 2025 | Aug 6, 2025 | M · derivative | 17,000 | $15.52 | $263,840 | not reported | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Aug 4, 2025 | Aug 6, 2025 | M | 18,889 | $22.89 | $432,369 | 45,898 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Aug 4, 2025 | Aug 6, 2025 | S | 18,889 | $32.89 | Sale −$621,259 | 27,009 | Yes | Form 4 |
| Ragosa MarkCHIEF FINANCIAL OFFICER | Aug 4, 2025 | Aug 6, 2025 | M · derivative | 18,889 | $22.89 | $432,369 | 2,036 | Yes | Form 4 |
| Megna Michael RCHIEF ACCOUNTING OFFICER | Jul 15, 2025 | Aug 6, 2025 | A | 495 | $15.63 | $7,737 | 33,041 | Yes | Form 4 |
| Popovits Kimberly J | Jul 30, 2025 | Aug 1, 2025 | M | 45,748 | $10.36 | $473,949 | 58,294 | No | Form 4 |
| Popovits Kimberly J | Jul 30, 2025 | Aug 1, 2025 | M | 18,760 | $15.47 | $290,217 | 77,054 | No | Form 4 |
| Popovits Kimberly J | Jul 30, 2025 | Aug 1, 2025 | M | 64,508 | $29.90 | $1,928,789 | 12,546 | No | Form 4 |
| Popovits Kimberly J | Jul 30, 2025 | Aug 1, 2025 | M · derivative | 45,748 | $10.36 | $473,949 | not reported | No | Form 4 |
| Popovits Kimberly J | Jul 30, 2025 | Aug 1, 2025 | M · derivative | 18,760 | $15.47 | $290,217 | not reported | No | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Jul 14, 2025 | Jul 16, 2025 | M | 6,500 | $8.83 | $57,395 | 68,063 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Jul 14, 2025 | Jul 16, 2025 | S | 18,900 | $28.72 | Sale −$542,808 | 49,163 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Jul 14, 2025 | Jul 16, 2025 | M · derivative | 6,500 | $8.83 | $57,395 | 32,000 | Yes | Form 4 |
| Levy Richard S | Jul 1, 2025 | Jul 3, 2025 | M | 1,101 | not reported | not reported | 18,474 | No | Form 4 |
| Levy Richard S | Jul 1, 2025 | Jul 3, 2025 | A · derivative | 1,101 | $0.00 | $0 | 1,101 | No | Form 4 |
| Levy Richard S | Jul 1, 2025 | Jul 3, 2025 | M · derivative | 1,101 | $0.00 | $0 | not reported | No | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Jun 16, 2025 | Jun 18, 2025 | M | 6,500 | $8.83 | $57,395 | 78,863 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Jun 16, 2025 | Jun 18, 2025 | S | 17,300 | $28.28 | Sale −$489,244 | 61,563 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Jun 16, 2025 | Jun 18, 2025 | M · derivative | 6,500 | $8.83 | $57,395 | 38,500 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Jun 11, 2025 | Jun 11, 2025 | M | 45,042 | $10.36 | $466,635 | 117,405 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Jun 11, 2025 | Jun 11, 2025 | S | 45,042 | $30.51 | Sale −$1,374,231 | 72,363 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Jun 11, 2025 | Jun 11, 2025 | M · derivative | 45,042 | $10.36 | $466,635 | 38,928 | Yes | Form 4 |
| Quart Barry D | Jun 11, 2025 | Jun 11, 2025 | M | 12,336 | $3.80 | $46,877 | 24,882 | No | Form 4 |
| Quart Barry D | Jun 11, 2025 | Jun 11, 2025 | S | 12,336 | $30.39 | Sale −$374,891 | 12,546 | No | Form 4 |
| Quart Barry D | Jun 11, 2025 | Jun 11, 2025 | M · derivative | 12,336 | $3.80 | $46,877 | not reported | No | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Jun 10, 2025 | Jun 11, 2025 | M | 15,506 | $10.36 | $160,642 | 87,869 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Jun 10, 2025 | Jun 11, 2025 | S | 15,506 | $30.46 | Sale −$472,313 | 72,363 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Jun 10, 2025 | Jun 11, 2025 | M · derivative | 15,506 | $10.36 | $160,642 | 83,970 | Yes | Form 4 |
| Quart Barry D | Jun 10, 2025 | Jun 11, 2025 | M | 8,212 | $3.80 | $31,206 | 20,758 | No | Form 4 |
| Quart Barry D | Jun 10, 2025 | Jun 11, 2025 | S | 8,212 | $30.36 | Sale −$249,316 | 12,546 | No | Form 4 |
| Quart Barry D | Jun 10, 2025 | Jun 11, 2025 | M · derivative | 8,212 | $3.80 | $31,206 | 12,336 | No | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Jun 9, 2025 | Jun 11, 2025 | M | 10,319 | $10.36 | $106,905 | 82,682 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Jun 9, 2025 | Jun 11, 2025 | S | 10,319 | $30.38 | Sale −$313,491 | 72,363 | Yes | Form 4 |
| Tessari EbenCHIEF OPERATING OFFICER | Jun 9, 2025 | Jun 11, 2025 | M · derivative | 10,319 | $10.36 | $106,905 | 99,476 | Yes | Form 4 |
| Quart Barry D | Jun 9, 2025 | Jun 11, 2025 | M | 6,900 | $3.80 | $26,220 | 19,446 | No | Form 4 |
| Quart Barry D | Jun 9, 2025 | Jun 11, 2025 | S | 6,900 | $30.26 | Sale −$208,794 | 12,546 | No | Form 4 |
| Quart Barry D | Jun 9, 2025 | Jun 11, 2025 | M · derivative | 6,900 | $3.80 | $26,220 | 20,548 | No | Form 4 |
| Quart Barry D | Jun 5, 2025 | Jun 5, 2025 | M | 3,173 | not reported | not reported | 12,546 | No | Form 4 |
| Quart Barry D | Jun 5, 2025 | Jun 5, 2025 | M · derivative | 3,173 | $0.00 | $0 | not reported | No | Form 4 |
| Popovits Kimberly J | Jun 5, 2025 | Jun 5, 2025 | M | 3,173 | not reported | not reported | 12,546 | No | Form 4 |
| Popovits Kimberly J | Jun 5, 2025 | Jun 5, 2025 | M · derivative | 3,173 | $0.00 | $0 | not reported | No | Form 4 |
| McCain Tracey L | Jun 5, 2025 | Jun 5, 2025 | M | 3,173 | not reported | not reported | 12,546 | No | Form 4 |
| McCain Tracey L | Jun 5, 2025 | Jun 5, 2025 | M · derivative | 3,173 | $0.00 | $0 | not reported | No | Form 4 |
| Malley Thomas | Jun 5, 2025 | Jun 5, 2025 | M | 3,173 | not reported | not reported | 12,546 | No | Form 4 |
| Malley Thomas | Jun 5, 2025 | Jun 5, 2025 | M · derivative | 3,173 | $0.00 | $0 | not reported | No | Form 4 |
| Levy Richard S | Jun 5, 2025 | Jun 5, 2025 | M | 3,173 | not reported | not reported | 17,373 | No | Form 4 |
| Levy Richard S | Jun 5, 2025 | Jun 5, 2025 | M · derivative | 3,173 | $0.00 | $0 | not reported | No | Form 4 |
| Cole G Bradley | Jun 5, 2025 | Jun 5, 2025 | M | 3,173 | not reported | not reported | 12,546 | No | Form 4 |
| Cole G Bradley | Jun 5, 2025 | Jun 5, 2025 | M · derivative | 3,173 | $0.00 | $0 | not reported | No | Form 4 |