MIRMMirum Pharmaceuticals, Inc.
- Market cap
- $5.22B
- as of 2026-10-23
- Latest close
- $80.39
- as of 2026-10-23
- Sector
- Healthcare
- as of 2026-10-24
- Industry
- Biotechnology
- as of 2026-10-24
Cluster
No cluster in the last 90 days under the default rule (14d · ≥2 insiders · all roles).
Form 4 historysince 2023-11-14
| Insider | Traded | Filed | Type | Shares | Price | Value | Owned after | 10b5-1 plan | Filing |
|---|---|---|---|---|---|---|---|---|---|
| Howe JolandaSVP, GLOBAL CONTROLLER | Oct 16 | Oct 19 | M | 16,112 | $19.24 | $309,995 | 16,728 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Oct 16 | Oct 19 | M · derivative | 16,112 | $19.24 | $309,995 | 8,888 | No | Form 4 |
| Myers Robert PaulChief Medical Officer | Oct 9 | Oct 14 | A · derivative | 40,000 | $86.01 | $3,440,400 | 40,000 | No | Form 4 |
| Myers Robert PaulChief Medical Officer | Oct 9 | Oct 14 | A · derivative | 25,000 | $0.00 | $0 | 25,000 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Oct 6 | Oct 6 | M | 5,305 | $19.19 | $101,803 | 199,745 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Oct 6 | Oct 6 | M | 6,892 | $15.87 | $109,376 | 206,637 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Oct 6 | Oct 6 | M · derivative | 5,305 | $19.19 | $101,803 | 169,695 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Oct 6 | Oct 6 | M · derivative | 6,892 | $15.87 | $109,376 | 233,108 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Sep 14 | Sep 15 | S | 9,943 | $98.37 | Sale −$978,093 | 44,745 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Sep 11 | Sep 15 | M | 18,333 | not reported | not reported | 54,688 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Sep 11 | Sep 15 | M · derivative | 18,333 | $0.00 | $0 | not reported | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Sep 2 | Sep 3 | S | 658 | $100.00 | Sale −$65,800 | 616 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Sep 1 | Sep 3 | M | 30,000 | $2.94 | $88,200 | 224,440 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Sep 1 | Sep 3 | S | 8,312 | $98.08 | Sale −$815,241 | 216,128 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Sep 1 | Sep 3 | S | 21,688 | $98.91 | Sale −$2,145,160 | 194,440 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Sep 1 | Sep 3 | M · derivative | 30,000 | $2.94 | $88,200 | 58,487 | Yes | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Aug 18 | Aug 19 | M | 40,000 | $6.27 | $250,800 | 41,274 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Aug 18 | Aug 19 | S | 40,000 | $100.00 | Sale −$4,000,000 | 1,274 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Aug 18 | Aug 19 | M · derivative | 40,000 | $6.27 | $250,800 | not reported | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Aug 11 | Aug 12 | S | 6,001 | $99.90 | Sale −$599,500 | 36,355 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Aug 10 | Aug 11 | M | 20,000 | $2.94 | $58,800 | 214,309 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Aug 10 | Aug 11 | S | 11,683 | $98.51 | Sale −$1,150,892 | 202,626 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Aug 10 | Aug 11 | S | 6,017 | $99.25 | Sale −$597,187 | 196,609 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Aug 10 | Aug 11 | S | 2,300 | $100.14 | Sale −$230,322 | 194,309 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Aug 10 | Aug 11 | M · derivative | 20,000 | $2.94 | $58,800 | 88,487 | Yes | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Aug 3 | Aug 5 | S | 1,840 | $105.29 | Sale −$193,734 | 1,274 | Yes | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jul 6 | Jul 8 | S | 3,124 | $121.67 | Sale −$380,097 | 44,057 | Yes | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jul 6 | Jul 8 | S | 1,048 | $122.43 | Sale −$128,307 | 43,009 | Yes | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jul 6 | Jul 8 | S | 528 | $123.84 | Sale −$65,388 | 42,481 | Yes | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jul 6 | Jul 8 | S | 300 | $124.94 | Sale −$37,482 | 42,181 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jul 6 | Jul 8 | M | 20,000 | $2.94 | $58,800 | 214,309 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jul 6 | Jul 8 | S | 12,134 | $121.65 | Sale −$1,476,101 | 202,175 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jul 6 | Jul 8 | S | 4,181 | $122.34 | Sale −$511,504 | 197,994 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jul 6 | Jul 8 | S | 1,975 | $123.74 | Sale −$244,387 | 196,019 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jul 6 | Jul 8 | S | 1,710 | $124.79 | Sale −$213,391 | 194,309 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jul 6 | Jul 8 | M · derivative | 20,000 | $2.94 | $58,800 | 108,487 | Yes | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jul 1 | Jul 2 | S | 2,721 | $120.00 | Sale −$326,520 | 3,114 | Yes | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jun 17 | Jun 18 | S | 2,594 | $101.95 | Sale −$264,458 | 5,835 | Yes | Form 4 |
| Grey Michael G | Jun 15 | Jun 17 | A · derivative | 3,772 | $101.00 | $380,972 | 3,772 | No | Form 4 |
| Grey Michael G | Jun 15 | Jun 17 | A · derivative | 1,980 | $0.00 | $0 | 1,980 | No | Form 4 |
| Walbert Timothy P | Jun 15 | Jun 17 | A · derivative | 3,772 | $101.00 | $380,972 | 3,772 | No | Form 4 |
| Walbert Timothy P | Jun 15 | Jun 17 | A · derivative | 1,980 | $0.00 | $0 | 1,980 | No | Form 4 |
| Heron Patrick J | Jun 15 | Jun 17 | A · derivative | 3,772 | $101.00 | $380,972 | 3,772 | No | Form 4 |
| Heron Patrick J | Jun 15 | Jun 17 | A · derivative | 1,980 | $0.00 | $0 | 1,980 | No | Form 4 |
| Brege Laura | Jun 15 | Jun 17 | A · derivative | 3,772 | $101.00 | $380,972 | 3,772 | No | Form 4 |
| Brege Laura | Jun 15 | Jun 17 | A · derivative | 1,980 | $0.00 | $0 | 1,980 | No | Form 4 |
| Fischer Laurent | Jun 15 | Jun 17 | A · derivative | 3,772 | $101.00 | $380,972 | 3,772 | No | Form 4 |
| Fischer Laurent | Jun 15 | Jun 17 | A · derivative | 1,980 | $0.00 | $0 | 1,980 | No | Form 4 |
| Ramasastry Saira | Jun 15 | Jun 17 | A · derivative | 3,772 | $101.00 | $380,972 | 3,772 | No | Form 4 |
| Ramasastry Saira | Jun 15 | Jun 17 | A · derivative | 1,980 | $0.00 | $0 | 1,980 | No | Form 4 |
| Fairey William | Jun 15 | Jun 17 | A · derivative | 3,772 | $101.00 | $380,972 | 3,772 | No | Form 4 |
| Fairey William | Jun 15 | Jun 17 | A · derivative | 1,980 | $0.00 | $0 | 1,980 | No | Form 4 |
| Cardon Lon | Jun 15 | Jun 17 | A · derivative | 3,772 | $101.00 | $380,972 | 3,772 | No | Form 4 |
| Cardon Lon | Jun 15 | Jun 17 | A · derivative | 1,980 | $0.00 | $0 | 1,980 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jun 9 | Jun 9 | M | 2,393 | $26.49 | $63,391 | 47,181 | Yes | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jun 9 | Jun 9 | M · derivative | 2,393 | $26.49 | $63,391 | 26,653 | Yes | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jun 8 | Jun 9 | S | 2,258 | $92.84 | Sale −$209,633 | 47,530 | Yes | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jun 8 | Jun 9 | S | 1,175 | $93.95 | Sale −$110,391 | 46,355 | Yes | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jun 8 | Jun 9 | S | 1,567 | $95.12 | Sale −$149,053 | 44,788 | Yes | Form 4 |
| Radovich PeterPRESIDENT AND COO | Jun 5 | Jun 8 | M | 16,988 | $19.19 | $326,000 | 57,260 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Jun 5 | Jun 8 | M · derivative | 16,988 | $19.19 | $326,000 | 48,012 | No | Form 4 |
| Ramasastry Saira | Jun 1 | Jun 2 | S | 3,977 | $100.00 | Sale −$397,700 | not reported | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jun 1 | Jun 2 | M | 30,000 | $2.94 | $88,200 | 224,309 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jun 1 | Jun 2 | S | 2,602 | $94.64 | Sale −$246,253 | 221,707 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jun 1 | Jun 2 | S | 16,595 | $95.34 | Sale −$1,582,167 | 205,112 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jun 1 | Jun 2 | S | 6,926 | $96.15 | Sale −$665,935 | 198,186 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jun 1 | Jun 2 | S | 1,973 | $97.56 | Sale −$192,486 | 196,213 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jun 1 | Jun 2 | S | 1,021 | $98.20 | Sale −$100,262 | 195,192 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jun 1 | Jun 2 | S | 883 | $99.66 | Sale −$88,000 | 194,309 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jun 1 | Jun 2 | M · derivative | 30,000 | $2.94 | $88,200 | 128,487 | Yes | Form 4 |
| Walbert Timothy P | May 29 | Jun 2 | M | 3,977 | not reported | not reported | 9,680 | No | Form 4 |
| Walbert Timothy P | May 29 | Jun 2 | M · derivative | 3,977 | $0.00 | $0 | not reported | No | Form 4 |
| Fischer Laurent | May 29 | Jun 2 | M | 3,977 | not reported | not reported | 10,727 | No | Form 4 |
| Fischer Laurent | May 29 | Jun 2 | M · derivative | 3,977 | $0.00 | $0 | not reported | No | Form 4 |
| Ramasastry Saira | May 29 | Jun 2 | M | 3,977 | not reported | not reported | 3,977 | No | Form 4 |
| Ramasastry Saira | May 29 | Jun 2 | M · derivative | 3,977 | $0.00 | $0 | not reported | No | Form 4 |
| Cardon Lon | May 29 | Jun 2 | M | 3,977 | not reported | not reported | 9,680 | No | Form 4 |
| Cardon Lon | May 29 | Jun 2 | M · derivative | 3,977 | $0.00 | $0 | not reported | No | Form 4 |
| Ramasastry Saira | May 15 | May 18 | M | 2,000 | $23.51 | $47,020 | 2,000 | Yes | Form 4 |
| Ramasastry Saira | May 15 | May 18 | S | 2,000 | $109.47 | Sale −$218,940 | not reported | Yes | Form 4 |
| Ramasastry Saira | May 15 | May 18 | M · derivative | 2,000 | $23.51 | $47,020 | not reported | Yes | Form 4 |
| Ramasastry Saira | Apr 15 | Apr 16 | M | 2,000 | $23.51 | $47,020 | 2,000 | Yes | Form 4 |
| Ramasastry Saira | Apr 15 | Apr 16 | S | 2,000 | $96.90 | Sale −$193,800 | not reported | Yes | Form 4 |
| Ramasastry Saira | Apr 15 | Apr 16 | M · derivative | 2,000 | $23.51 | $47,020 | 2,000 | Yes | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Mar 16 | Mar 17 | S | 7,287 | $91.98 | Sale −$670,258 | 49,788 | No | Form 4 |
| Ramasastry Saira | Mar 16 | Mar 17 | M | 2,000 | $23.51 | $47,020 | 2,000 | Yes | Form 4 |
| Ramasastry Saira | Mar 16 | Mar 17 | S | 2,000 | $90.76 | Sale −$181,520 | not reported | Yes | Form 4 |
| Ramasastry Saira | Mar 16 | Mar 17 | M · derivative | 2,000 | $23.51 | $47,020 | 4,000 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Mar 16 | Mar 17 | S | 40,985 | $91.98 | Sale −$3,769,800 | 194,309 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Mar 16 | Mar 17 | S | 16,515 | $91.98 | Sale −$1,519,050 | 40,272 | No | Form 4 |
| Quan JoanneCHIEF MEDICAL OFFICER | Mar 16 | Mar 17 | S | 7,287 | $91.98 | Sale −$670,258 | 18,864 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Mar 16 | Mar 17 | S | 4,732 | $91.98 | Sale −$435,249 | 8,429 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Mar 15 | Mar 17 | M | 13,334 | not reported | not reported | 57,075 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Mar 15 | Mar 17 | M · derivative | 13,334 | $0.00 | $0 | 6,666 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Mar 15 | Mar 17 | M | 25,000 | not reported | not reported | 185,294 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Mar 15 | Mar 17 | M | 50,000 | not reported | not reported | 235,294 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Mar 15 | Mar 17 | M · derivative | 25,000 | $0.00 | $0 | not reported | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Mar 15 | Mar 17 | M · derivative | 50,000 | $0.00 | $0 | 25,000 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Mar 15 | Mar 17 | M | 7,220 | not reported | not reported | 33,787 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Mar 15 | Mar 17 | M | 23,000 | not reported | not reported | 56,787 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Mar 15 | Mar 17 | M · derivative | 7,220 | $0.00 | $0 | not reported | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Mar 15 | Mar 17 | M · derivative | 23,000 | $0.00 | $0 | 11,500 | No | Form 4 |
| Quan JoanneCHIEF MEDICAL OFFICER | Mar 15 | Mar 17 | M | 13,334 | not reported | not reported | 26,151 | No | Form 4 |
| Quan JoanneCHIEF MEDICAL OFFICER | Mar 15 | Mar 17 | M · derivative | 13,334 | $0.00 | $0 | 6,666 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Mar 15 | Mar 17 | M | 2,658 | not reported | not reported | 7,161 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Mar 15 | Mar 17 | M | 6,000 | not reported | not reported | 13,161 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Mar 15 | Mar 17 | M · derivative | 2,658 | $0.00 | $0 | not reported | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Mar 15 | Mar 17 | M · derivative | 6,000 | $0.00 | $0 | 3,000 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Mar 6 | Mar 11 | M | 5,912 | $15.87 | $93,823 | 26,567 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Mar 6 | Mar 11 | M · derivative | 5,912 | $15.87 | $93,823 | 54,088 | No | Form 4 |
| Ramasastry Saira | Feb 13 | Feb 17 | M | 2,000 | $23.51 | $47,020 | 2,000 | Yes | Form 4 |
| Ramasastry Saira | Feb 13 | Feb 17 | S | 2,000 | $102.09 | Sale −$204,180 | not reported | Yes | Form 4 |
| Ramasastry Saira | Feb 13 | Feb 17 | M · derivative | 2,000 | $23.51 | $47,020 | 6,000 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Feb 2 | Feb 3 | S | 9,108 | $103.30 | Sale −$940,856 | 160,294 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Feb 2 | Feb 3 | S | 2,631 | $103.30 | Sale −$271,782 | 20,655 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Feb 2 | Feb 3 | S | 968 | $103.30 | Sale −$99,994 | 4,503 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 31 | Feb 3 | M | 1,771 | not reported | not reported | 5,471 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 31 | Feb 3 | M · derivative | 1,771 | $0.00 | $0 | not reported | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jan 28 | Jan 30 | A · derivative | 18,140 | $100.85 | $1,829,419 | 18,140 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jan 28 | Jan 30 | A · derivative | 11,760 | $0.00 | $0 | 11,760 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jan 28 | Jan 30 | A · derivative | 20,000 | $0.00 | $0 | 20,000 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jan 28 | Jan 30 | A · derivative | 67,000 | $100.85 | $6,756,950 | 67,000 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jan 28 | Jan 30 | A · derivative | 43,500 | $0.00 | $0 | 43,500 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jan 28 | Jan 30 | A · derivative | 75,000 | $0.00 | $0 | 75,000 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Jan 28 | Jan 30 | A · derivative | 25,120 | $100.85 | $2,533,352 | 25,120 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Jan 28 | Jan 30 | A · derivative | 16,280 | $0.00 | $0 | 16,280 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Jan 28 | Jan 30 | A · derivative | 34,500 | $0.00 | $0 | 34,500 | No | Form 4 |
| Quan JoanneCHIEF MEDICAL OFFICER | Jan 28 | Jan 30 | A · derivative | 18,140 | $100.85 | $1,829,419 | 18,140 | No | Form 4 |
| Quan JoanneCHIEF MEDICAL OFFICER | Jan 28 | Jan 30 | A · derivative | 11,760 | $0.00 | $0 | 11,760 | No | Form 4 |
| Quan JoanneCHIEF MEDICAL OFFICER | Jan 28 | Jan 30 | A · derivative | 20,000 | $0.00 | $0 | 20,000 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 28 | Jan 30 | A · derivative | 7,680 | $100.85 | $774,528 | 7,680 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 28 | Jan 30 | A · derivative | 4,970 | $0.00 | $0 | 4,970 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 28 | Jan 30 | A · derivative | 9,000 | $0.00 | $0 | 9,000 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jan 26 | Jan 27 | S | 1,053 | $96.19 | Sale −$101,288 | 43,741 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jan 26 | Jan 27 | S | 6,831 | $96.19 | Sale −$657,074 | 169,402 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Jan 26 | Jan 27 | S | 3,143 | $96.19 | Sale −$302,325 | 23,286 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 26 | Jan 27 | S | 842 | $96.19 | Sale −$80,992 | 3,700 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jan 23 | Jan 27 | M | 2,667 | not reported | not reported | 44,794 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jan 23 | Jan 27 | M · derivative | 2,667 | $0.00 | $0 | 2,666 | No | Form 4 |
| Heron Patrick J | Jan 23 | Jan 27 | J | 159,277 | not reported | not reported | 327,585 | No | Form 4 |
| Heron Patrick J | Jan 23 | Jan 27 | P | 131,425 | $68.48 | Purchase +$8,999,984 | 459,010 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jan 23 | Jan 27 | M | 12,500 | not reported | not reported | 176,233 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jan 23 | Jan 27 | M · derivative | 12,500 | $0.00 | $0 | 12,500 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Jan 23 | Jan 27 | M | 5,750 | not reported | not reported | 26,429 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Jan 23 | Jan 27 | M · derivative | 5,750 | $0.00 | $0 | 5,750 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 23 | Jan 27 | M | 1,500 | not reported | not reported | 4,542 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 23 | Jan 27 | M · derivative | 1,500 | $0.00 | $0 | 1,500 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jan 22 | Jan 23 | S | 1,421 | $93.33 | Sale −$132,622 | 42,127 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jan 22 | Jan 23 | S | 7,098 | $93.33 | Sale −$662,456 | 163,733 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Jan 22 | Jan 23 | S | 2,382 | $93.33 | Sale −$222,312 | 20,679 | No | Form 4 |
| Quan JoanneCHIEF MEDICAL OFFICER | Jan 22 | Jan 23 | S | 1,822 | $93.33 | Sale −$170,047 | 12,817 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 22 | Jan 23 | S | 926 | $93.33 | Sale −$86,424 | 3,042 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jan 21 | Jan 23 | M | 3,334 | not reported | not reported | 43,548 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jan 21 | Jan 23 | M · derivative | 3,334 | $0.00 | $0 | 6,666 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jan 21 | Jan 23 | M | 12,797 | not reported | not reported | 170,831 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jan 21 | Jan 23 | M · derivative | 12,797 | $0.00 | $0 | 25,593 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Jan 21 | Jan 23 | M | 4,167 | not reported | not reported | 23,061 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Jan 21 | Jan 23 | M · derivative | 4,167 | $0.00 | $0 | 8,333 | No | Form 4 |
| Quan JoanneCHIEF MEDICAL OFFICER | Jan 21 | Jan 23 | M | 3,334 | not reported | not reported | 14,639 | No | Form 4 |
| Quan JoanneCHIEF MEDICAL OFFICER | Jan 21 | Jan 23 | M · derivative | 3,334 | $0.00 | $0 | 6,666 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 21 | Jan 23 | M | 1,542 | not reported | not reported | 3,968 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 21 | Jan 23 | M · derivative | 1,542 | $0.00 | $0 | 3,083 | No | Form 4 |
| Quan JoanneCHIEF MEDICAL OFFICER | Jan 20 | Jan 21 | S | 6,911 | $90.27 | Sale −$623,856 | 11,305 | No | Form 4 |
| Quan JoanneCHIEF MEDICAL OFFICER | Jan 16 | Jan 21 | M | 12,500 | not reported | not reported | 18,216 | No | Form 4 |
| Quan JoanneCHIEF MEDICAL OFFICER | Jan 16 | Jan 21 | M · derivative | 12,500 | $0.00 | $0 | 12,500 | No | Form 4 |
| Ramasastry Saira | Jan 15 | Jan 16 | M | 2,000 | $23.51 | $47,020 | 2,000 | Yes | Form 4 |
| Ramasastry Saira | Jan 15 | Jan 16 | S | 2,000 | $90.99 | Sale −$181,980 | not reported | Yes | Form 4 |
| Ramasastry Saira | Jan 15 | Jan 16 | M · derivative | 2,000 | $23.51 | $47,020 | 8,000 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Dec 31, 2025 | Jan 2 | G | 21,070 | $0.00 | $0 | 187,500 | No | Form 4 |
| Ramasastry Saira | Dec 22, 2025 | Dec 23, 2025 | M | 5,000 | $23.51 | $117,550 | 5,000 | Yes | Form 4 |
| Ramasastry Saira | Dec 22, 2025 | Dec 23, 2025 | S | 5,000 | $80.00 | Sale −$400,000 | not reported | Yes | Form 4 |
| Ramasastry Saira | Dec 22, 2025 | Dec 23, 2025 | M · derivative | 5,000 | $23.51 | $117,550 | 10,000 | Yes | Form 4 |
| Grey Michael G | Dec 19, 2025 | Dec 23, 2025 | M | 50,000 | $2.94 | $147,000 | 50,000 | Yes | Form 4 |
| Grey Michael G | Dec 19, 2025 | Dec 23, 2025 | S | 50,000 | $78.00 | Sale −$3,900,000 | not reported | Yes | Form 4 |
| Grey Michael G | Dec 19, 2025 | Dec 23, 2025 | M · derivative | 50,000 | $2.94 | $147,000 | 181,176 | Yes | Form 4 |
| Ramasastry Saira | Dec 18, 2025 | Dec 19, 2025 | M | 2,000 | $23.51 | $47,020 | 2,000 | Yes | Form 4 |
| Ramasastry Saira | Dec 18, 2025 | Dec 19, 2025 | S | 1,000 | $69.46 | Sale −$69,460 | 1,000 | Yes | Form 4 |
| Ramasastry Saira | Dec 18, 2025 | Dec 19, 2025 | S | 1,000 | $70.00 | Sale −$70,000 | not reported | Yes | Form 4 |
| Ramasastry Saira | Dec 18, 2025 | Dec 19, 2025 | M · derivative | 2,000 | $23.51 | $47,020 | 15,000 | Yes | Form 4 |
| Grey Michael G | Dec 1, 2025 | Dec 2, 2025 | M | 50,000 | $2.94 | $147,000 | 50,000 | Yes | Form 4 |
| Grey Michael G | Dec 1, 2025 | Dec 2, 2025 | S | 50,000 | $74.00 | Sale −$3,700,000 | not reported | Yes | Form 4 |
| Grey Michael G | Dec 1, 2025 | Dec 2, 2025 | M · derivative | 50,000 | $2.94 | $147,000 | 231,176 | Yes | Form 4 |
| Grey Michael G | Nov 21, 2025 | Nov 25, 2025 | M | 50,000 | $2.94 | $147,000 | 50,000 | Yes | Form 4 |
| Grey Michael G | Nov 21, 2025 | Nov 25, 2025 | S | 50,000 | $70.00 | Sale −$3,500,000 | not reported | Yes | Form 4 |
| Grey Michael G | Nov 21, 2025 | Nov 25, 2025 | M · derivative | 50,000 | $2.94 | $147,000 | 281,176 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Nov 18, 2025 | Nov 20, 2025 | M | 19,133 | $19.24 | $368,119 | 158,034 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Nov 18, 2025 | Nov 20, 2025 | M · derivative | 19,133 | $19.24 | $368,119 | 150,867 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Sep 12, 2025 | Sep 12, 2025 | S | 9,578 | $76.01 | Sale −$728,024 | 39,945 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Sep 11, 2025 | Sep 12, 2025 | M | 18,333 | not reported | not reported | 49,523 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Sep 11, 2025 | Sep 12, 2025 | M · derivative | 18,333 | $0.00 | $0 | 18,333 | No | Form 4 |
| Brege Laura | Sep 11, 2025 | Sep 12, 2025 | M | 17,000 | $15.00 | $255,000 | 32,703 | No | Form 4 |
| Brege Laura | Sep 11, 2025 | Sep 12, 2025 | S | 15,509 | $74.34 | Sale −$1,152,939 | 17,194 | No | Form 4 |
| Brege Laura | Sep 11, 2025 | Sep 12, 2025 | S | 1,491 | $75.07 | Sale −$111,929 | 15,703 | No | Form 4 |
| Brege Laura | Sep 11, 2025 | Sep 12, 2025 | M · derivative | 17,000 | $15.00 | $255,000 | not reported | No | Form 4 |
| Ramasastry Saira | Sep 8, 2025 | Sep 10, 2025 | M | 17,000 | $23.51 | $399,670 | 17,000 | No | Form 4 |
| Ramasastry Saira | Sep 8, 2025 | Sep 10, 2025 | S | 17,000 | not reported | Sale not reported | not reported | No | Form 4 |
| Ramasastry Saira | Sep 8, 2025 | Sep 10, 2025 | M · derivative | 17,000 | $23.51 | $399,670 | 17,000 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Aug 12, 2025 | Aug 12, 2025 | M | 2,954 | $26.49 | $78,251 | 31,190 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Aug 12, 2025 | Aug 12, 2025 | M · derivative | 2,954 | $26.49 | $78,251 | 29,046 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Aug 11, 2025 | Aug 12, 2025 | M | 40,000 | $2.94 | $117,600 | 178,641 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Aug 11, 2025 | Aug 12, 2025 | S | 40,000 | $62.00 | Sale −$2,480,000 | 138,641 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Aug 11, 2025 | Aug 12, 2025 | M · derivative | 40,000 | $2.94 | $117,600 | 158,487 | Yes | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Aug 11, 2025 | Aug 12, 2025 | S | 8,000 | not reported | Sale not reported | 28,236 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Aug 7, 2025 | Aug 8, 2025 | M | 40,000 | $2.94 | $117,600 | 178,641 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Aug 7, 2025 | Aug 8, 2025 | S | 40,000 | $55.25 | Sale −$2,210,000 | 138,641 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Aug 7, 2025 | Aug 8, 2025 | M · derivative | 40,000 | $2.94 | $117,600 | 198,487 | Yes | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Aug 7, 2025 | Aug 8, 2025 | M | 10,000 | $6.27 | $62,700 | 12,426 | Yes | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Aug 7, 2025 | Aug 8, 2025 | S | 10,000 | $58.00 | Sale −$580,000 | 2,426 | Yes | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Aug 7, 2025 | Aug 8, 2025 | M · derivative | 10,000 | $6.27 | $62,700 | 40,000 | Yes | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jul 3, 2025 | Jul 3, 2025 | S | 477 | $49.08 | Sale −$23,411 | 2,426 | Yes | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jul 2, 2025 | Jul 3, 2025 | S | 564 | $48.25 | Sale −$27,213 | 2,903 | Yes | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jul 1, 2025 | Jul 3, 2025 | M | 1,041 | not reported | not reported | 3,467 | Yes | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jul 1, 2025 | Jul 3, 2025 | M · derivative | 1,041 | $0.00 | $0 | not reported | Yes | Form 4 |
| Fairey William | Jun 11, 2025 | Jun 13, 2025 | S | 3,203 | $48.42 | Sale −$155,089 | 2,500 | No | Form 4 |
| Ramasastry Saira | Jun 3, 2025 | Jun 4, 2025 | M | 2,500 | $14.12 | $35,300 | 2,500 | No | Form 4 |
| Ramasastry Saira | Jun 3, 2025 | Jun 4, 2025 | S | 2,500 | $45.74 | Sale −$114,350 | not reported | No | Form 4 |
| Ramasastry Saira | Jun 3, 2025 | Jun 4, 2025 | M · derivative | 2,500 | $14.12 | $35,300 | not reported | No | Form 4 |
| Ramasastry Saira | Jun 2, 2025 | Jun 4, 2025 | S | 5,703 | $46.20 | Sale −$263,479 | not reported | No | Form 4 |
| Walbert Timothy P | May 29, 2025 | Jun 2, 2025 | M | 5,703 | not reported | not reported | 5,703 | No | Form 4 |
| Walbert Timothy P | May 29, 2025 | Jun 2, 2025 | M · derivative | 5,703 | $0.00 | $0 | not reported | No | Form 4 |
| Walbert Timothy P | May 29, 2025 | Jun 2, 2025 | A · derivative | 6,268 | $44.00 | $275,792 | 6,268 | No | Form 4 |
| Walbert Timothy P | May 29, 2025 | Jun 2, 2025 | A · derivative | 3,977 | $0.00 | $0 | 3,977 | No | Form 4 |
| Fischer Laurent | May 29, 2025 | Jun 2, 2025 | A · derivative | 6,268 | $44.00 | $275,792 | 6,268 | No | Form 4 |
| Fischer Laurent | May 29, 2025 | Jun 2, 2025 | A · derivative | 3,977 | $0.00 | $0 | 3,977 | No | Form 4 |
| Cardon Lon | May 29, 2025 | Jun 2, 2025 | M | 5,703 | not reported | not reported | 5,703 | No | Form 4 |
| Cardon Lon | May 29, 2025 | Jun 2, 2025 | M · derivative | 5,703 | $0.00 | $0 | not reported | No | Form 4 |
| Cardon Lon | May 29, 2025 | Jun 2, 2025 | A · derivative | 6,268 | $44.00 | $275,792 | 6,268 | No | Form 4 |
| Cardon Lon | May 29, 2025 | Jun 2, 2025 | A · derivative | 3,977 | $0.00 | $0 | 3,977 | No | Form 4 |
| Fairey William | May 29, 2025 | Jun 2, 2025 | M | 5,703 | not reported | not reported | 5,703 | No | Form 4 |
| Fairey William | May 29, 2025 | Jun 2, 2025 | M · derivative | 5,703 | $0.00 | $0 | not reported | No | Form 4 |
| Fairey William | May 29, 2025 | Jun 2, 2025 | A · derivative | 6,268 | $44.00 | $275,792 | 6,268 | No | Form 4 |
| Fairey William | May 29, 2025 | Jun 2, 2025 | A · derivative | 3,977 | $0.00 | $0 | 3,977 | No | Form 4 |
| Brege Laura | May 29, 2025 | Jun 2, 2025 | M | 5,703 | not reported | not reported | 15,703 | No | Form 4 |
| Brege Laura | May 29, 2025 | Jun 2, 2025 | M · derivative | 5,703 | $0.00 | $0 | not reported | No | Form 4 |
| Brege Laura | May 29, 2025 | Jun 2, 2025 | A · derivative | 6,268 | $44.00 | $275,792 | 6,268 | No | Form 4 |
| Brege Laura | May 29, 2025 | Jun 2, 2025 | A · derivative | 3,977 | $0.00 | $0 | 3,977 | No | Form 4 |
| Grey Michael G | May 29, 2025 | Jun 2, 2025 | A · derivative | 6,268 | $44.00 | $275,792 | 6,268 | No | Form 4 |
| Grey Michael G | May 29, 2025 | Jun 2, 2025 | A · derivative | 3,977 | $0.00 | $0 | 3,977 | No | Form 4 |
| Heron Patrick J | May 29, 2025 | Jun 2, 2025 | M | 5,703 | not reported | not reported | 5,703 | No | Form 4 |
| Heron Patrick J | May 29, 2025 | Jun 2, 2025 | M · derivative | 5,703 | $0.00 | $0 | not reported | No | Form 4 |
| Heron Patrick J | May 29, 2025 | Jun 2, 2025 | A · derivative | 6,268 | $44.00 | $275,792 | 6,268 | No | Form 4 |
| Heron Patrick J | May 29, 2025 | Jun 2, 2025 | A · derivative | 3,977 | $0.00 | $0 | 3,977 | No | Form 4 |
| Ramasastry Saira | May 29, 2025 | Jun 2, 2025 | M | 5,703 | not reported | not reported | 5,703 | No | Form 4 |
| Ramasastry Saira | May 29, 2025 | Jun 2, 2025 | M · derivative | 5,703 | $0.00 | $0 | not reported | No | Form 4 |
| Ramasastry Saira | May 29, 2025 | Jun 2, 2025 | A · derivative | 6,268 | $44.00 | $275,792 | 6,268 | No | Form 4 |
| Ramasastry Saira | May 29, 2025 | Jun 2, 2025 | A · derivative | 3,977 | $0.00 | $0 | 3,977 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Mar 18, 2025 | Mar 19, 2025 | S | 2,415 | $44.45 | Sale −$107,347 | 2,426 | Yes | Form 4 |
| Heron Patrick J | Mar 17, 2025 | Mar 18, 2025 | P | 21 | $43.93 | Purchase +$923 | 168,672 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Mar 17, 2025 | Mar 18, 2025 | S | 27,279 | $44.21 | Sale −$1,206,005 | 138,641 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Mar 17, 2025 | Mar 18, 2025 | S | 7,879 | $44.21 | Sale −$348,331 | 18,672 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Mar 17, 2025 | Mar 18, 2025 | S | 2,900 | $44.21 | Sale −$128,209 | 6,647 | Yes | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Mar 17, 2025 | Mar 18, 2025 | M | 52,900 | $2.94 | $155,526 | 59,547 | Yes | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Mar 17, 2025 | Mar 18, 2025 | S | 50,111 | $44.33 | Sale −$2,221,421 | 9,436 | Yes | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Mar 17, 2025 | Mar 18, 2025 | S | 2,789 | $44.75 | Sale −$124,808 | 6,647 | Yes | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Mar 17, 2025 | Mar 18, 2025 | S | 1,806 | $44.36 | Sale −$80,114 | 4,841 | Yes | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Mar 17, 2025 | Mar 18, 2025 | M · derivative | 52,900 | $2.94 | $155,526 | not reported | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Mar 15, 2025 | Mar 18, 2025 | M | 50,000 | not reported | not reported | 165,920 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Mar 15, 2025 | Mar 18, 2025 | M · derivative | 50,000 | $0.00 | $0 | 25,000 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Mar 15, 2025 | Mar 18, 2025 | M | 14,440 | not reported | not reported | 26,551 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Mar 15, 2025 | Mar 18, 2025 | M · derivative | 14,440 | $0.00 | $0 | 7,220 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Mar 15, 2025 | Mar 18, 2025 | M | 5,315 | not reported | not reported | 9,547 | Yes | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Mar 15, 2025 | Mar 18, 2025 | M · derivative | 5,315 | $0.00 | $0 | 2,658 | Yes | Form 4 |
| Heron Patrick J | Mar 14, 2025 | Mar 18, 2025 | P | 528 | $44.11 | Purchase +$23,290 | 168,651 | No | Form 4 |
| Heron Patrick J | Mar 11, 2025 | Mar 12, 2025 | P | 963 | $43.77 | Purchase +$42,151 | 168,123 | No | Form 4 |
| Heron Patrick J | Mar 10, 2025 | Mar 12, 2025 | P | 758 | $42.66 | Purchase +$32,336 | 166,583 | No | Form 4 |
| Heron Patrick J | Mar 10, 2025 | Mar 12, 2025 | P | 577 | $43.37 | Purchase +$25,024 | 167,160 | No | Form 4 |
| Heron Patrick J | Mar 7, 2025 | Mar 10, 2025 | P | 580 | $43.21 | Purchase +$25,062 | 165,825 | No | Form 4 |
| Heron Patrick J | Mar 6, 2025 | Mar 10, 2025 | P | 1,335 | $43.89 | Purchase +$58,593 | 165,245 | No | Form 4 |
| Heron Patrick J | Mar 5, 2025 | Mar 6, 2025 | P | 267 | $44.55 | Purchase +$11,895 | 163,910 | No | Form 4 |
| Heron Patrick J | Mar 4, 2025 | Mar 6, 2025 | P | 1,279 | $45.55 | Purchase +$58,258 | 163,587 | No | Form 4 |
| Heron Patrick J | Mar 4, 2025 | Mar 6, 2025 | P | 56 | $45.96 | Purchase +$2,574 | 163,643 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Mar 4, 2025 | Mar 5, 2025 | S | 13,681 | $45.57 | Sale −$623,443 | 13,280 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Mar 4, 2025 | Mar 5, 2025 | S | 1,169 | $45.74 | Sale −$53,470 | 12,111 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Mar 3, 2025 | Mar 4, 2025 | M | 40,000 | $2.94 | $117,600 | 155,920 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Mar 3, 2025 | Mar 4, 2025 | S | 19,392 | $46.61 | Sale −$903,861 | 136,528 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Mar 3, 2025 | Mar 4, 2025 | S | 20,608 | $47.19 | Sale −$972,492 | 115,920 | Yes | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Mar 3, 2025 | Mar 4, 2025 | M · derivative | 40,000 | $2.94 | $117,600 | 238,487 | Yes | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Feb 3, 2025 | Feb 4, 2025 | S | 1,064 | $48.22 | Sale −$51,306 | 4,232 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Feb 3, 2025 | Feb 4, 2025 | S | 9,102 | $48.22 | Sale −$438,898 | 115,920 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Feb 3, 2025 | Feb 4, 2025 | S | 2,627 | $48.22 | Sale −$126,674 | 26,961 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 31, 2025 | Feb 4, 2025 | M | 1,772 | not reported | not reported | 5,296 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 31, 2025 | Feb 4, 2025 | M · derivative | 1,772 | $0.00 | $0 | 1,771 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jan 24, 2025 | Jan 27, 2025 | S | 6,837 | $47.92 | Sale −$327,629 | 125,022 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 24, 2025 | Jan 27, 2025 | S | 902 | $47.92 | Sale −$43,224 | 3,524 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Jan 24, 2025 | Jan 27, 2025 | S | 3,177 | $47.92 | Sale −$152,242 | 29,588 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jan 23, 2025 | Jan 27, 2025 | M | 12,500 | not reported | not reported | 131,859 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jan 23, 2025 | Jan 27, 2025 | M · derivative | 12,500 | $0.00 | $0 | 25,000 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 23, 2025 | Jan 27, 2025 | M | 1,500 | not reported | not reported | 4,426 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 23, 2025 | Jan 27, 2025 | M · derivative | 1,500 | $0.00 | $0 | 3,000 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jan 23, 2025 | Jan 27, 2025 | M | 2,667 | not reported | not reported | 35,946 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jan 23, 2025 | Jan 27, 2025 | M · derivative | 2,667 | $0.00 | $0 | 5,333 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Jan 23, 2025 | Jan 27, 2025 | M | 5,750 | not reported | not reported | 32,765 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Jan 23, 2025 | Jan 27, 2025 | M · derivative | 5,750 | $0.00 | $0 | 11,500 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jan 21, 2025 | Jan 23, 2025 | A · derivative | 153,550 | $47.98 | $7,367,329 | 153,550 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jan 21, 2025 | Jan 23, 2025 | A · derivative | 38,390 | $0.00 | $0 | 38,390 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jan 21, 2025 | Jan 23, 2025 | A · derivative | 75,000 | $0.00 | $0 | 75,000 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Jan 21, 2025 | Jan 23, 2025 | A · derivative | 50,000 | $47.98 | $2,399,000 | 50,000 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Jan 21, 2025 | Jan 23, 2025 | A · derivative | 12,500 | $0.00 | $0 | 12,500 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Jan 21, 2025 | Jan 23, 2025 | A · derivative | 21,660 | $0.00 | $0 | 21,660 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jan 21, 2025 | Jan 23, 2025 | A · derivative | 40,000 | $47.98 | $1,919,200 | 40,000 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jan 21, 2025 | Jan 23, 2025 | A · derivative | 10,000 | $0.00 | $0 | 10,000 | No | Form 4 |
| Quan JoanneCHIEF MEDICAL OFFICER | Jan 21, 2025 | Jan 23, 2025 | A · derivative | 40,000 | $47.98 | $1,919,200 | 40,000 | No | Form 4 |
| Quan JoanneCHIEF MEDICAL OFFICER | Jan 21, 2025 | Jan 23, 2025 | A · derivative | 10,000 | $0.00 | $0 | 10,000 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 21, 2025 | Jan 23, 2025 | A · derivative | 18,500 | $47.98 | $887,630 | 18,500 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 21, 2025 | Jan 23, 2025 | A · derivative | 4,625 | $0.00 | $0 | 4,625 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 21, 2025 | Jan 23, 2025 | A · derivative | 7,973 | $0.00 | $0 | 7,973 | No | Form 4 |
| Quan JoanneCHIEF MEDICAL OFFICER | Jan 17, 2025 | Jan 21, 2025 | S | 6,969 | $45.86 | Sale −$319,598 | 5,649 | No | Form 4 |
| Quan JoanneCHIEF MEDICAL OFFICER | Jan 16, 2025 | Jan 21, 2025 | M | 12,500 | not reported | not reported | 12,618 | No | Form 4 |
| Quan JoanneCHIEF MEDICAL OFFICER | Jan 16, 2025 | Jan 21, 2025 | M · derivative | 12,500 | $0.00 | $0 | 25,000 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 7, 2025 | Jan 8, 2025 | S | 750 | $42.82 | Sale −$32,115 | 2,926 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jan 7, 2025 | Jan 8, 2025 | S | 7,489 | $42.82 | Sale −$320,679 | 119,359 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Jan 7, 2025 | Jan 8, 2025 | S | 1,998 | $42.82 | Sale −$85,554 | 27,015 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 6, 2025 | Jan 8, 2025 | M | 1,250 | not reported | not reported | 3,676 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 6, 2025 | Jan 8, 2025 | M · derivative | 1,250 | $0.00 | $0 | not reported | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Nov 14, 2024 | Nov 15, 2024 | M | 2,500 | $2.94 | $7,350 | 4,926 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Nov 14, 2024 | Nov 15, 2024 | S | 2,500 | $47.10 | Sale −$117,750 | 2,426 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Nov 14, 2024 | Nov 15, 2024 | M · derivative | 2,500 | $2.94 | $7,350 | 52,900 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Nov 8, 2024 | Nov 14, 2024 | A | 65 | $21.05 | $1,368 | 126,848 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Nov 8, 2024 | Nov 14, 2024 | A | 475 | $21.05 | $9,999 | 33,279 | No | Form 4 |
| Quan JoanneCHIEF MEDICAL OFFICER | Nov 8, 2024 | Nov 14, 2024 | A | 118 | $21.05 | $2,484 | 118 | No | Form 4 |
| Grey Michael G | Sep 27, 2024 | Oct 1, 2024 | G | 102,788 | $0.00 | $0 | 186,410 | No | Form 4 |
| Heron Patrick J | Sep 18, 2024 | Sep 20, 2024 | P | 115 | $37.40 | Purchase +$4,301 | 162,308 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Sep 11, 2024 | Sep 12, 2024 | M | 18,334 | not reported | not reported | 32,804 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Sep 11, 2024 | Sep 12, 2024 | M · derivative | 18,334 | $0.00 | $0 | 36,666 | No | Form 4 |
| Heron Patrick J | Sep 6, 2024 | Sep 10, 2024 | P | 230 | $41.58 | Purchase +$9,563 | 162,193 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jul 23, 2024 | Jul 24, 2024 | M | 34,013 | $2.94 | $99,998 | 126,783 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jul 23, 2024 | Jul 24, 2024 | M · derivative | 34,013 | $2.94 | $99,998 | 278,487 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jul 2, 2024 | Jul 3, 2024 | S | 375 | $34.00 | Sale −$12,750 | 2,426 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jul 1, 2024 | Jul 3, 2024 | M | 1,042 | not reported | not reported | 2,801 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jul 1, 2024 | Jul 3, 2024 | M · derivative | 1,042 | $0.00 | $0 | 1,041 | No | Form 4 |
| Vig PamelaCHIEF SCIENTIFIC OFFICER | Jun 24, 2024 | Jun 25, 2024 | M | 30,559 | $2.94 | $89,843 | 57,965 | Yes | Form 4 |
| Vig PamelaCHIEF SCIENTIFIC OFFICER | Jun 24, 2024 | Jun 25, 2024 | S | 30,559 | $34.00 | Sale −$1,039,006 | 27,406 | Yes | Form 4 |
| Vig PamelaCHIEF SCIENTIFIC OFFICER | Jun 24, 2024 | Jun 25, 2024 | M · derivative | 30,559 | $2.94 | $89,843 | 125,691 | Yes | Form 4 |
| Fairey William | Jun 5, 2024 | Jun 7, 2024 | A · derivative | 8,779 | $26.30 | $230,888 | 8,779 | Yes | Form 4 |
| Fairey William | Jun 5, 2024 | Jun 7, 2024 | A · derivative | 5,703 | $0.00 | $0 | 5,703 | Yes | Form 4 |
| Ramasastry Saira | Jun 5, 2024 | Jun 7, 2024 | M | 5,000 | $14.12 | $70,600 | 5,000 | Yes | Form 4 |
| Ramasastry Saira | Jun 5, 2024 | Jun 7, 2024 | S | 5,000 | $25.68 | Sale −$128,400 | not reported | Yes | Form 4 |
| Ramasastry Saira | Jun 5, 2024 | Jun 7, 2024 | M · derivative | 5,000 | $14.12 | $70,600 | 2,500 | Yes | Form 4 |
| Ramasastry Saira | Jun 5, 2024 | Jun 7, 2024 | A · derivative | 8,779 | $26.30 | $230,888 | 8,779 | Yes | Form 4 |
| Ramasastry Saira | Jun 5, 2024 | Jun 7, 2024 | A · derivative | 5,703 | $0.00 | $0 | 5,703 | Yes | Form 4 |
| Fischer Laurent | Jun 5, 2024 | Jun 7, 2024 | A · derivative | 8,779 | $26.30 | $230,888 | 8,779 | No | Form 4 |
| Fischer Laurent | Jun 5, 2024 | Jun 7, 2024 | A · derivative | 5,703 | $0.00 | $0 | 5,703 | No | Form 4 |
| Heron Patrick J | Jun 5, 2024 | Jun 7, 2024 | A · derivative | 8,779 | $26.30 | $230,888 | 8,779 | Yes | Form 4 |
| Heron Patrick J | Jun 5, 2024 | Jun 7, 2024 | A · derivative | 5,703 | $0.00 | $0 | 5,703 | Yes | Form 4 |
| Brege Laura | Jun 5, 2024 | Jun 7, 2024 | A · derivative | 8,779 | $26.30 | $230,888 | 8,779 | Yes | Form 4 |
| Brege Laura | Jun 5, 2024 | Jun 7, 2024 | A · derivative | 5,703 | $0.00 | $0 | 5,703 | Yes | Form 4 |
| Cardon Lon | Jun 5, 2024 | Jun 7, 2024 | A · derivative | 8,779 | $26.30 | $230,888 | 8,779 | Yes | Form 4 |
| Cardon Lon | Jun 5, 2024 | Jun 7, 2024 | A · derivative | 5,703 | $0.00 | $0 | 5,703 | Yes | Form 4 |
| Walbert Timothy P | Jun 5, 2024 | Jun 7, 2024 | A · derivative | 8,779 | $26.30 | $230,888 | 8,779 | Yes | Form 4 |
| Walbert Timothy P | Jun 5, 2024 | Jun 7, 2024 | A · derivative | 5,703 | $0.00 | $0 | 5,703 | Yes | Form 4 |
| Grey Michael G | Jun 5, 2024 | Jun 7, 2024 | A · derivative | 8,779 | $26.30 | $230,888 | 8,779 | No | Form 4 |
| Grey Michael G | Jun 5, 2024 | Jun 7, 2024 | A · derivative | 5,703 | $0.00 | $0 | 5,703 | No | Form 4 |
| Vig PamelaCHIEF SCIENTIFIC OFFICER | May 10, 2024 | May 16, 2024 | A | 94 | $21.05 | $1,979 | 27,406 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | May 10, 2024 | May 16, 2024 | A | 817 | $21.05 | $17,198 | 92,770 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | May 10, 2024 | May 16, 2024 | A | 470 | $21.05 | $9,894 | 14,470 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Mar 27, 2024 | Mar 27, 2024 | P | 2,000 | $24.80 | Purchase +$49,600 | 14,000 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Mar 25, 2024 | Mar 25, 2024 | S | 4,303 | $25.80 | Sale −$111,017 | 29,013 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Mar 18, 2024 | Mar 18, 2024 | P | 2,000 | $25.80 | Purchase +$51,600 | 12,000 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jan 9, 2023 | Mar 18, 2024 | S | 5,159 | $20.62 | Sale −$106,379 | 91,953 | No | Form 4 |
| Longpre LaraCHIEF DEVELOPMENT OFFICER | Jan 9, 2023 | Mar 18, 2024 | S | 1,003 | $20.62 | Sale −$20,682 | 104,369 | No | Form 4 |
| Vig PamelaCHIEF SCIENTIFIC OFFICER | Jan 9, 2023 | Mar 18, 2024 | S | 1,379 | $20.62 | Sale −$28,435 | 27,312 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Jan 9, 2023 | Mar 18, 2024 | S | 1,379 | $20.62 | Sale −$28,435 | 33,316 | No | Form 4 |
| Longpre LaraCHIEF DEVELOPMENT OFFICER | Sep 10, 2019 | Mar 18, 2024 | P | 965 | $10.64 | Purchase +$10,268 | 105,372 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Feb 2, 2024 | Feb 5, 2024 | S | 6,013 | $26.19 | Sale −$157,480 | 104,112 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Feb 2, 2024 | Feb 5, 2024 | S | 1,790 | $26.19 | Sale −$46,880 | 34,695 | No | Form 4 |
| Longpre LaraCHIEF DEVELOPMENT OFFICER | Feb 2, 2024 | Feb 5, 2024 | S | 847 | $26.19 | Sale −$22,183 | 104,407 | No | Form 4 |
| Vig PamelaCHIEF SCIENTIFIC OFFICER | Feb 2, 2024 | Feb 5, 2024 | S | 1,214 | $26.19 | Sale −$31,795 | 28,691 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Feb 2, 2024 | Feb 2, 2024 | S | 735 | $26.19 | Sale −$19,250 | 1,759 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 31, 2024 | Feb 2, 2024 | M | 1,772 | not reported | not reported | 2,494 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 31, 2024 | Feb 2, 2024 | M · derivative | 1,772 | $0.00 | $0 | 3,543 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jan 23, 2024 | Jan 25, 2024 | A · derivative | 150,000 | $26.49 | $3,973,500 | 150,000 | No | Form 4 |
| Peetz ChristopherCHIEF EXECUTIVE OFFICER | Jan 23, 2024 | Jan 25, 2024 | A · derivative | 37,500 | $0.00 | $0 | 37,500 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Jan 23, 2024 | Jan 25, 2024 | A · derivative | 70,000 | $26.49 | $1,854,300 | 70,000 | No | Form 4 |
| Radovich PeterPRESIDENT AND COO | Jan 23, 2024 | Jan 25, 2024 | A · derivative | 17,250 | $0.00 | $0 | 17,250 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jan 23, 2024 | Jan 25, 2024 | A · derivative | 32,000 | $26.49 | $847,680 | 32,000 | No | Form 4 |
| Bjerkholt EricCHIEF FINANCIAL OFFICER | Jan 23, 2024 | Jan 25, 2024 | A · derivative | 8,000 | $0.00 | $0 | 8,000 | No | Form 4 |
| Longpre LaraCHIEF DEVELOPMENT OFFICER | Jan 23, 2024 | Jan 25, 2024 | A · derivative | 32,000 | $26.49 | $847,680 | 32,000 | No | Form 4 |
| Longpre LaraCHIEF DEVELOPMENT OFFICER | Jan 23, 2024 | Jan 25, 2024 | A · derivative | 8,000 | $0.00 | $0 | 8,000 | No | Form 4 |
| Vig PamelaCHIEF SCIENTIFIC OFFICER | Jan 23, 2024 | Jan 25, 2024 | A · derivative | 32,000 | $26.49 | $847,680 | 32,000 | No | Form 4 |
| Vig PamelaCHIEF SCIENTIFIC OFFICER | Jan 23, 2024 | Jan 25, 2024 | A · derivative | 8,000 | $0.00 | $0 | 8,000 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 23, 2024 | Jan 25, 2024 | A · derivative | 18,000 | $26.49 | $476,820 | 18,000 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 23, 2024 | Jan 25, 2024 | A · derivative | 4,500 | $0.00 | $0 | 4,500 | No | Form 4 |
| Quan JoanneCHIEF MEDICAL OFFICER | Jan 16, 2024 | Jan 18, 2024 | A · derivative | 75,000 | $26.72 | $2,004,000 | 75,000 | No | Form 4 |
| Quan JoanneCHIEF MEDICAL OFFICER | Jan 16, 2024 | Jan 18, 2024 | A · derivative | 37,500 | $0.00 | $0 | 37,500 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 8, 2024 | Jan 9, 2024 | S | 528 | $28.04 | Sale −$14,805 | 722 | No | Form 4 |
| Peetz ChristopherPRESIDENT AND CEO | Jan 8, 2024 | Jan 9, 2024 | S | 5,209 | $28.03 | Sale −$146,008 | 110,125 | No | Form 4 |
| Vig PamelaHEAD OF RESEARCH & DEVELOPMENT | Jan 8, 2024 | Jan 9, 2024 | S | 1,408 | $28.03 | Sale −$39,466 | 29,905 | No | Form 4 |
| Longpre LaraCHIEF DEVELOPMENT OFFICER | Jan 8, 2024 | Jan 9, 2024 | S | 1,019 | $28.04 | Sale −$28,573 | 105,254 | No | Form 4 |
| Radovich PeterCHIEF OPERATING OFFICER | Jan 8, 2024 | Jan 9, 2024 | S | 1,408 | $28.03 | Sale −$39,466 | 36,485 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 6, 2024 | Jan 9, 2024 | M | 1,250 | not reported | not reported | 1,250 | No | Form 4 |
| Howe JolandaSVP, GLOBAL CONTROLLER | Jan 6, 2024 | Jan 9, 2024 | M · derivative | 1,250 | $0.00 | $0 | 1,250 | No | Form 4 |
| Howe JolandaSVP, Global Controller | Dec 5, 2023 | Dec 6, 2023 | M | 2,500 | $2.94 | $7,350 | 2,500 | No | Form 4 |
| Howe JolandaSVP, Global Controller | Dec 5, 2023 | Dec 6, 2023 | S | 2,500 | $32.40 | Sale −$81,000 | not reported | No | Form 4 |
| Howe JolandaSVP, Global Controller | Dec 5, 2023 | Dec 6, 2023 | M · derivative | 2,500 | $2.94 | $7,350 | 55,400 | No | Form 4 |
| Radovich PeterChief Operating Officer | Nov 10, 2023 | Nov 15, 2023 | A | 218 | $22.29 | $4,859 | 37,893 | No | Form 4 |
| Longpre LaraChief Development Officer | Nov 10, 2023 | Nov 15, 2023 | A | 434 | $22.29 | $9,674 | 106,273 | No | Form 4 |
| Vig PamelaHead of Research & Development | Nov 10, 2023 | Nov 15, 2023 | A | 527 | $22.29 | $11,747 | 31,313 | No | Form 4 |
| Heron Patrick J | Nov 9, 2023 | Nov 14, 2023 | P | 2,910 | $28.30 | Purchase +$82,353 | 161,963 | No | Form 4 |