MLYSMineralys Therapeutics, Inc.
- Market cap
- $1.81B
- as of 2026-10-23
- Latest close
- $20.55
- as of 2026-10-23
- Sector
- Healthcare
- as of 2026-10-24
- Industry
- Biotechnology
- as of 2026-10-24
Cluster
No cluster in the last 90 days under the default rule (14d · ≥2 insiders · all roles).
Form 4 historysince 2023-11-07
| Insider | Traded | Filed | Type | Shares | Price | Value | Owned after | 10b5-1 plan | Filing |
|---|---|---|---|---|---|---|---|---|---|
| Peterson Kristine | Oct 19 | Oct 20 | A | 12,400 | $0.00 | $0 | 12,400 | No | Form 4 |
| Peterson Kristine | Oct 19 | Oct 20 | A · derivative | 16,600 | $20.92 | $347,272 | 16,600 | No | Form 4 |
| Coats Lonnel | Oct 19 | Oct 20 | A | 12,400 | $0.00 | $0 | 12,400 | No | Form 4 |
| Coats Lonnel | Oct 19 | Oct 20 | A · derivative | 16,600 | $20.92 | $347,272 | 16,600 | No | Form 4 |
| Congleton JonChief Executive Officer | Sep 30 | Oct 2 | S | 75,000 | $25.46 | Sale −$1,909,665 | 528,621 | Yes | Form 4 |
| Slingsby Brian Taylor | Sep 22 | Sep 24 | S | 104,320 | $28.81 | Sale −$3,005,459 | 7,805,718 | No | Form 4 |
| Warren EricChief Commercial Officer | Sep 21 | Sep 22 | M | 7,438 | $13.24 | $98,479 | 45,838 | Yes | Form 4 |
| Warren EricChief Commercial Officer | Sep 21 | Sep 22 | S | 7,438 | $28.12 | Sale −$209,157 | 38,400 | Yes | Form 4 |
| Warren EricChief Commercial Officer | Sep 21 | Sep 22 | M · derivative | 7,438 | $13.24 | $98,479 | 230,563 | Yes | Form 4 |
| Karydas Daphne | Sep 15 | Sep 17 | M | 3,000 | $12.02 | $36,060 | 9,200 | Yes | Form 4 |
| Karydas Daphne | Sep 15 | Sep 17 | S | 3,000 | $28.58 | Sale −$85,740 | 6,200 | Yes | Form 4 |
| Karydas Daphne | Sep 15 | Sep 17 | M · derivative | 3,000 | $12.02 | $36,060 | 35,000 | Yes | Form 4 |
| Warren EricChief Commercial Officer | Aug 21 | Aug 25 | M | 7,437 | $13.24 | $98,466 | 45,837 | Yes | Form 4 |
| Warren EricChief Commercial Officer | Aug 21 | Aug 25 | S | 7,437 | $25.98 | Sale −$193,213 | 38,400 | Yes | Form 4 |
| Warren EricChief Commercial Officer | Aug 21 | Aug 25 | M · derivative | 7,437 | $13.24 | $98,466 | 238,001 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Aug 10 | Aug 12 | M | 2,170 | $16.00 | $34,720 | 53,554 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Aug 10 | Aug 12 | S | 2,170 | $27.09 | Sale −$58,785 | 51,384 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Aug 10 | Aug 12 | M · derivative | 2,170 | $16.00 | $34,720 | 13,024 | Yes | Form 4 |
| Ferguson James J. IIIChief Medical Officer | Aug 10 | Aug 12 | A | 102,400 | $0.00 | $0 | 102,400 | No | Form 4 |
| Ferguson James J. IIIChief Medical Officer | Aug 10 | Aug 12 | A · derivative | 135,000 | $27.38 | $3,696,300 | 135,000 | No | Form 4 |
| Warren EricChief Commercial Officer | Jul 21 | Jul 23 | M | 7,438 | $13.24 | $98,479 | 45,838 | Yes | Form 4 |
| Warren EricChief Commercial Officer | Jul 21 | Jul 23 | S | 7,438 | $26.87 | Sale −$199,859 | 38,400 | Yes | Form 4 |
| Warren EricChief Commercial Officer | Jul 21 | Jul 23 | M · derivative | 7,438 | $13.24 | $98,479 | 245,438 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 17 | Jul 20 | M | 416 | $15.44 | $6,423 | 51,800 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 17 | Jul 20 | S | 416 | $26.53 | Sale −$11,036 | 51,384 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 17 | Jul 20 | M · derivative | 416 | $15.44 | $6,423 | 3,334 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 15 | Jul 15 | S | 6,349 | $26.61 | Sale −$168,947 | 51,384 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 13 | Jul 15 | M | 3,542 | $10.20 | $36,128 | 61,275 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 13 | Jul 15 | M | 4,167 | $14.25 | $59,380 | 65,442 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 13 | Jul 15 | M | 6,349 | $1.08 | $6,857 | 71,791 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 13 | Jul 15 | S | 14,058 | $27.58 | Sale −$387,720 | 57,733 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 13 | Jul 15 | M · derivative | 3,542 | $10.20 | $36,128 | 109,792 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 13 | Jul 15 | M · derivative | 4,167 | $14.25 | $59,380 | 79,167 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 13 | Jul 15 | M · derivative | 6,349 | $1.08 | $6,857 | not reported | Yes | Form 4 |
| Congleton JonChief Executive Officer | Jul 13 | Jul 15 | S | 10,700 | $27.24 | Sale −$291,468 | 603,621 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 9 | Jul 10 | M | 2,171 | $16.00 | $34,736 | 59,904 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 9 | Jul 10 | S | 2,171 | $30.30 | Sale −$65,781 | 57,733 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 9 | Jul 10 | M · derivative | 2,171 | $16.00 | $34,736 | 15,194 | Yes | Form 4 |
| Congleton JonChief Executive Officer | Jun 30 | Jun 30 | S | 58,000 | $25.94 | Sale −$1,504,520 | 631,321 | Yes | Form 4 |
| Congleton JonChief Executive Officer | Jun 30 | Jun 30 | S | 17,000 | $26.82 | Sale −$455,940 | 614,321 | Yes | Form 4 |
| Warren EricChief Commercial Officer | Jun 26 | Jun 30 | M | 104,124 | $13.24 | $1,378,602 | 142,524 | Yes | Form 4 |
| Warren EricChief Commercial Officer | Jun 26 | Jun 30 | S | 104,124 | $25.90 | Sale −$2,696,812 | 38,400 | Yes | Form 4 |
| Warren EricChief Commercial Officer | Jun 26 | Jun 30 | M · derivative | 104,124 | $13.24 | $1,378,602 | 252,876 | Yes | Form 4 |
| Karydas Daphne | Jun 17 | Jun 17 | M | 3,000 | $12.02 | $36,060 | 9,200 | Yes | Form 4 |
| Karydas Daphne | Jun 17 | Jun 17 | S | 3,000 | $25.00 | Sale −$75,000 | 6,200 | Yes | Form 4 |
| Karydas Daphne | Jun 17 | Jun 17 | M · derivative | 3,000 | $12.02 | $36,060 | 38,000 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jun 17 | Jun 17 | M | 4,167 | $14.25 | $59,380 | 61,262 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jun 17 | Jun 17 | M | 417 | $15.44 | $6,438 | 61,679 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jun 17 | Jun 17 | S | 4,584 | $25.00 | Sale −$114,600 | 57,095 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jun 17 | Jun 17 | M · derivative | 4,167 | $14.25 | $59,380 | 83,334 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jun 17 | Jun 17 | M · derivative | 417 | $15.44 | $6,438 | 3,750 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jun 15 | Jun 17 | M | 3,542 | $10.20 | $36,128 | 66,985 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jun 15 | Jun 17 | S | 9,890 | $23.81 | Sale −$235,481 | 57,095 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jun 15 | Jun 17 | M · derivative | 3,542 | $10.20 | $36,128 | 113,334 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jun 12 | Jun 12 | M | 6,349 | $1.08 | $6,857 | 69,792 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jun 12 | Jun 12 | S | 6,349 | $23.93 | Sale −$151,932 | 63,443 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jun 12 | Jun 12 | M · derivative | 6,349 | $1.08 | $6,857 | 6,349 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jun 10 | Jun 12 | M | 2,170 | $16.00 | $34,720 | 65,613 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jun 10 | Jun 12 | S | 2,170 | $25.00 | Sale −$54,250 | 63,443 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jun 10 | Jun 12 | M · derivative | 2,170 | $16.00 | $34,720 | 17,365 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | May 18 | May 19 | M | 417 | $15.44 | $6,438 | 63,860 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | May 18 | May 19 | S | 417 | $27.55 | Sale −$11,488 | 63,443 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | May 18 | May 19 | M · derivative | 417 | $15.44 | $6,438 | 4,167 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | May 13 | May 13 | M | 3,541 | $10.20 | $36,118 | 73,333 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | May 13 | May 13 | M | 4,166 | $14.25 | $59,366 | 77,499 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | May 13 | May 13 | S | 14,056 | $28.58 | Sale −$401,720 | 63,443 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | May 13 | May 13 | M · derivative | 3,541 | $10.20 | $36,118 | 116,876 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | May 13 | May 13 | M · derivative | 4,166 | $14.25 | $59,366 | 87,501 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | May 12 | May 13 | M | 6,348 | $1.08 | $6,856 | 76,140 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | May 12 | May 13 | S | 6,348 | $29.36 | Sale −$186,377 | 69,792 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | May 12 | May 13 | M · derivative | 6,348 | $1.08 | $6,856 | 12,698 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | May 11 | May 13 | M | 2,171 | $16.00 | $34,736 | 71,963 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | May 11 | May 13 | S | 2,171 | $29.71 | Sale −$64,500 | 69,792 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | May 11 | May 13 | M · derivative | 2,171 | $16.00 | $34,736 | 19,535 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 17 | Apr 21 | M | 416 | $15.44 | $6,423 | 70,208 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 17 | Apr 21 | S | 416 | $31.33 | Sale −$13,033 | 69,792 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 17 | Apr 21 | M · derivative | 416 | $15.44 | $6,423 | 4,584 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 15 | Apr 15 | S | 6,348 | $27.66 | Sale −$175,586 | 69,792 | Yes | Form 4 |
| Congleton JonChief Executive Officer | Apr 13 | Apr 15 | S | 15,730 | $26.83 | Sale −$422,036 | 689,321 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 13 | Apr 15 | M | 6,349 | $1.08 | $6,857 | 82,489 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 13 | Apr 15 | M | 3,542 | $10.20 | $36,128 | 86,031 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 13 | Apr 15 | M | 4,167 | $14.25 | $59,380 | 90,198 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 13 | Apr 15 | S | 14,058 | $26.54 | Sale −$373,099 | 76,140 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 13 | Apr 15 | M · derivative | 6,349 | $1.08 | $6,857 | 19,046 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 13 | Apr 15 | M · derivative | 3,542 | $10.20 | $36,128 | 120,417 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 13 | Apr 15 | M · derivative | 4,167 | $14.25 | $59,380 | 91,667 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 9 | Apr 13 | M | 2,170 | $16.00 | $34,720 | 78,310 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 9 | Apr 13 | S | 2,170 | $27.38 | Sale −$59,415 | 76,140 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 9 | Apr 13 | M · derivative | 2,170 | $16.00 | $34,720 | 21,706 | Yes | Form 4 |
| Congleton JonChief Executive Officer | Mar 31 | Apr 2 | S | 19,364 | $25.50 | Sale −$493,782 | 760,687 | Yes | Form 4 |
| Congleton JonChief Executive Officer | Mar 31 | Apr 2 | S | 55,183 | $26.54 | Sale −$1,464,557 | 705,504 | Yes | Form 4 |
| Congleton JonChief Executive Officer | Mar 31 | Apr 2 | S | 453 | $27.05 | Sale −$12,254 | 705,051 | Yes | Form 4 |
| Karydas Daphne | Mar 31 | Apr 2 | M | 3,000 | $12.02 | $36,060 | 9,200 | Yes | Form 4 |
| Karydas Daphne | Mar 31 | Apr 2 | S | 3,000 | $25.00 | Sale −$75,000 | 6,200 | Yes | Form 4 |
| Karydas Daphne | Mar 31 | Apr 2 | M · derivative | 3,000 | $12.02 | $36,060 | 41,000 | Yes | Form 4 |
| Shah Rajeev M. | Mar 30 | Mar 31 | P | 58,300 | $24.16 | Purchase +$1,408,528 | 5,825,521 | No | Form 4 |
| Shah Rajeev M. | Mar 27 | Mar 31 | P | 310,700 | $23.67 | Purchase +$7,354,269 | 5,767,221 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 17 | Mar 17 | M | 417 | $15.44 | $6,438 | 76,557 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 17 | Mar 17 | S | 417 | $25.65 | Sale −$10,696 | 76,140 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 17 | Mar 17 | M · derivative | 417 | $15.44 | $6,438 | 5,000 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 13 | Mar 16 | M | 3,542 | $10.20 | $36,128 | 86,031 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 13 | Mar 16 | M | 4,167 | $14.25 | $59,380 | 90,198 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 13 | Mar 16 | S | 10,726 | $25.91 | Sale −$277,911 | 79,472 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 13 | Mar 16 | S | 3,079 | $27.37 | Sale −$84,272 | 76,393 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 13 | Mar 16 | S | 253 | $27.82 | Sale −$7,038 | 76,140 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 13 | Mar 16 | M · derivative | 3,542 | $10.20 | $36,128 | 123,959 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 13 | Mar 16 | M · derivative | 4,167 | $14.25 | $59,380 | 95,834 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 12 | Mar 16 | M | 6,348 | $1.08 | $6,856 | 88,837 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 12 | Mar 16 | S | 6,348 | $27.37 | Sale −$173,745 | 82,489 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 12 | Mar 16 | M · derivative | 6,348 | $1.08 | $6,856 | 25,395 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 9 | Mar 10 | M | 2,171 | $16.00 | $34,736 | 84,660 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 9 | Mar 10 | S | 2,171 | $26.84 | Sale −$58,270 | 82,489 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 9 | Mar 10 | M · derivative | 2,171 | $16.00 | $34,736 | 23,876 | Yes | Form 4 |
| RA Capital Healthcare Fund LP | Feb 19 | Feb 20 | A | 6,200 | $0.00 | $0 | 6,200 | No | Form 4 |
| RA Capital Healthcare Fund LP | Feb 19 | Feb 20 | A · derivative | 8,300 | $28.06 | $232,898 | 8,300 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Feb 19 | Feb 20 | A | 39,900 | $0.00 | $0 | 48,538 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Feb 19 | Feb 20 | A · derivative | 53,300 | $28.06 | $1,495,598 | 53,300 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 19 | Feb 20 | A | 38,400 | $0.00 | $0 | 82,489 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 19 | Feb 20 | A · derivative | 51,300 | $28.06 | $1,439,478 | 51,300 | No | Form 4 |
| DiRocco Derek | Feb 19 | Feb 20 | A | 6,200 | $0.00 | $0 | 6,200 | No | Form 4 |
| DiRocco Derek | Feb 19 | Feb 20 | A · derivative | 8,300 | $28.06 | $232,898 | 8,300 | No | Form 4 |
| Akkaraju Srinivas | Feb 19 | Feb 20 | A | 6,200 | $0.00 | $0 | 6,200 | No | Form 4 |
| Akkaraju Srinivas | Feb 19 | Feb 20 | A · derivative | 8,300 | $28.06 | $232,898 | 8,300 | No | Form 4 |
| Slingsby Brian Taylor | Feb 19 | Feb 20 | A | 6,200 | $0.00 | $0 | 6,200 | No | Form 4 |
| Slingsby Brian Taylor | Feb 19 | Feb 20 | J | 6,200 | $0.00 | $0 | not reported | No | Form 4 |
| Slingsby Brian Taylor | Feb 19 | Feb 20 | J | 6,200 | $0.00 | $0 | 7,910,038 | No | Form 4 |
| Slingsby Brian Taylor | Feb 19 | Feb 20 | A · derivative | 8,300 | $28.06 | $232,898 | 8,300 | No | Form 4 |
| Slingsby Brian Taylor | Feb 19 | Feb 20 | J · derivative | 8,300 | $28.06 | $232,898 | not reported | No | Form 4 |
| Slingsby Brian Taylor | Feb 19 | Feb 20 | J · derivative | 8,300 | $28.06 | $232,898 | 8,300 | No | Form 4 |
| Karydas Daphne | Feb 19 | Feb 20 | A | 6,200 | $0.00 | $0 | 6,200 | No | Form 4 |
| Karydas Daphne | Feb 19 | Feb 20 | A · derivative | 8,300 | $28.06 | $232,898 | 8,300 | No | Form 4 |
| Gold Alexander M | Feb 19 | Feb 20 | A | 6,200 | $0.00 | $0 | 6,200 | No | Form 4 |
| Gold Alexander M | Feb 19 | Feb 20 | A · derivative | 8,300 | $28.06 | $232,898 | 8,300 | No | Form 4 |
| Sblendorio Glenn | Feb 19 | Feb 20 | A | 6,200 | $0.00 | $0 | 6,200 | No | Form 4 |
| Sblendorio Glenn | Feb 19 | Feb 20 | A · derivative | 8,300 | $28.06 | $232,898 | 8,300 | No | Form 4 |
| Congleton JonChief Executive Officer | Feb 19 | Feb 20 | A | 140,900 | $0.00 | $0 | 780,051 | No | Form 4 |
| Congleton JonChief Executive Officer | Feb 19 | Feb 20 | A · derivative | 187,900 | $28.06 | $5,272,474 | 187,900 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 17 | Feb 17 | M | 417 | $15.44 | $6,438 | 44,506 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 17 | Feb 17 | S | 417 | $27.59 | Sale −$11,505 | 44,089 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 17 | Feb 17 | M · derivative | 417 | $15.44 | $6,438 | 5,417 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 13 | Feb 13 | M | 3,541 | $10.20 | $36,118 | 53,978 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 13 | Feb 13 | S | 3,541 | $27.33 | Sale −$96,776 | 50,437 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 13 | Feb 13 | M | 4,166 | $14.25 | $59,366 | 54,603 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 13 | Feb 13 | S | 4,166 | $27.33 | Sale −$113,857 | 50,437 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 13 | Feb 13 | S | 6,348 | $27.58 | Sale −$175,078 | 44,089 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 13 | Feb 13 | M · derivative | 3,541 | $10.20 | $36,118 | 127,501 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 13 | Feb 13 | M · derivative | 4,166 | $14.25 | $59,366 | 100,001 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 12 | Feb 13 | M | 6,349 | $1.08 | $6,857 | 56,786 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 12 | Feb 13 | S | 5,828 | $28.94 | Sale −$168,662 | 50,958 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 12 | Feb 13 | S | 521 | $29.64 | Sale −$15,442 | 50,437 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 12 | Feb 13 | M · derivative | 6,349 | $1.08 | $6,857 | 31,743 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 9 | Feb 11 | M | 2,171 | $16.00 | $34,736 | 52,608 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 9 | Feb 11 | S | 2,171 | $30.21 | Sale −$65,586 | 50,437 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 9 | Feb 11 | M · derivative | 2,171 | $16.00 | $34,736 | 26,047 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 20 | Jan 20 | M | 416 | $15.44 | $6,423 | 50,853 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 20 | Jan 20 | S | 416 | $32.10 | Sale −$13,354 | 50,437 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 20 | Jan 20 | M · derivative | 416 | $15.44 | $6,423 | 5,834 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 14 | Jan 15 | S | 11,367 | $32.61 | Sale −$370,678 | 50,437 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 13 | Jan 15 | M | 3,542 | $10.20 | $36,128 | 65,346 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 13 | Jan 15 | M | 4,167 | $14.25 | $59,380 | 69,513 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 13 | Jan 15 | S | 7,709 | $32.75 | Sale −$252,470 | 61,804 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 13 | Jan 15 | M · derivative | 3,542 | $10.20 | $36,128 | 131,042 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 13 | Jan 15 | M · derivative | 4,167 | $14.25 | $59,380 | 104,167 | Yes | Form 4 |
| Congleton JonChief Executive Officer | Jan 12 | Jan 13 | S | 9,119 | $32.21 | Sale −$293,723 | 646,268 | Yes | Form 4 |
| Congleton JonChief Executive Officer | Jan 12 | Jan 13 | S | 7,117 | $33.15 | Sale −$235,929 | 639,151 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 12 | Jan 13 | M | 6,348 | $1.08 | $6,856 | 68,152 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 12 | Jan 13 | S | 6,348 | $32.32 | Sale −$205,167 | 61,804 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 12 | Jan 13 | M · derivative | 6,348 | $1.08 | $6,856 | 38,092 | Yes | Form 4 |
| Levy Adam ScottCFO and Secretary | Jan 12 | Jan 13 | S | 10,758 | $32.14 | Sale −$345,762 | 8,638 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 9 | Jan 13 | M | 2,170 | $16.00 | $34,720 | 63,974 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 9 | Jan 13 | S | 2,170 | $33.27 | Sale −$72,196 | 61,804 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 9 | Jan 13 | M · derivative | 2,170 | $16.00 | $34,720 | 28,218 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 5 | Jan 6 | M | 28,038 | $1.08 | $30,281 | 97,226 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 5 | Jan 6 | M | 10,121 | $15.44 | $156,268 | 107,347 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 5 | Jan 6 | M | 26,069 | $10.20 | $265,904 | 133,416 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 5 | Jan 6 | M | 53,630 | $16.00 | $858,080 | 187,046 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 5 | Jan 6 | M | 67,473 | $14.25 | $961,490 | 254,519 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 5 | Jan 6 | S | 139,245 | $34.83 | Sale −$4,849,903 | 115,274 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 5 | Jan 6 | S | 53,470 | $35.53 | Sale −$1,899,789 | 61,804 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 5 | Jan 6 | M · derivative | 28,038 | $1.08 | $30,281 | 44,440 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 5 | Jan 6 | M · derivative | 10,121 | $15.44 | $156,268 | 6,250 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 5 | Jan 6 | M · derivative | 26,069 | $10.20 | $265,904 | 134,584 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 5 | Jan 6 | M · derivative | 53,630 | $16.00 | $858,080 | 30,388 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 5 | Jan 6 | M · derivative | 67,473 | $14.25 | $961,490 | 108,334 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 2 | Jan 6 | M | 10,053 | $1.08 | $10,857 | 81,888 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 2 | Jan 6 | M | 3,629 | $15.44 | $56,032 | 85,517 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 2 | Jan 6 | M | 9,347 | $10.20 | $95,339 | 94,864 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 2 | Jan 6 | M | 20,168 | $16.00 | $322,688 | 115,032 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 2 | Jan 6 | M | 24,193 | $14.25 | $344,750 | 139,225 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 2 | Jan 6 | S | 70,037 | $35.87 | Sale −$2,512,227 | 69,188 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 2 | Jan 6 | M · derivative | 10,053 | $1.08 | $10,857 | 72,478 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 2 | Jan 6 | M · derivative | 3,629 | $15.44 | $56,032 | 16,371 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 2 | Jan 6 | M · derivative | 9,347 | $10.20 | $95,339 | 160,653 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 2 | Jan 6 | M · derivative | 20,168 | $16.00 | $322,688 | 84,018 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 2 | Jan 6 | M · derivative | 24,193 | $14.25 | $344,750 | 175,807 | Yes | Form 4 |
| Congleton JonChief Executive Officer | Nov 21, 2025 | Nov 24, 2025 | M | 24,082 | $0.54 | $13,004 | 655,387 | No | Form 4 |
| Congleton JonChief Executive Officer | Nov 21, 2025 | Nov 24, 2025 | M · derivative | 24,082 | $0.54 | $13,004 | not reported | No | Form 4 |
| Catalys Pacific Fund, LP | Nov 20, 2025 | Nov 21, 2025 | S | 1,000,000 | $43.35 | Sale −$43,350,000 | 7,903,838 | No | Form 4 |
| Gold Alexander M | Nov 13, 2025 | Nov 13, 2025 | M | 2,742 | $10.20 | $27,968 | 2,742 | No | Form 4 |
| Gold Alexander M | Nov 13, 2025 | Nov 13, 2025 | M | 10,000 | $12.69 | $126,900 | 12,742 | No | Form 4 |
| Gold Alexander M | Nov 13, 2025 | Nov 13, 2025 | S | 12,742 | $46.50 | Sale −$592,503 | not reported | No | Form 4 |
| Gold Alexander M | Nov 13, 2025 | Nov 13, 2025 | M · derivative | 2,742 | $10.20 | $27,968 | 8,225 | No | Form 4 |
| Gold Alexander M | Nov 13, 2025 | Nov 13, 2025 | M · derivative | 10,000 | $12.69 | $126,900 | 34,000 | No | Form 4 |
| Karydas Daphne | Nov 13, 2025 | Nov 13, 2025 | M | 15,000 | $10.20 | $153,000 | 15,000 | No | Form 4 |
| Karydas Daphne | Nov 13, 2025 | Nov 13, 2025 | S | 10,115 | $45.81 | Sale −$463,368 | 4,885 | No | Form 4 |
| Karydas Daphne | Nov 13, 2025 | Nov 13, 2025 | S | 4,885 | $46.36 | Sale −$226,469 | not reported | No | Form 4 |
| Karydas Daphne | Nov 13, 2025 | Nov 13, 2025 | M · derivative | 15,000 | $10.20 | $153,000 | 17,900 | No | Form 4 |
| Gold Alexander M | Nov 12, 2025 | Nov 13, 2025 | M | 6,933 | $10.20 | $70,717 | 6,933 | No | Form 4 |
| Gold Alexander M | Nov 12, 2025 | Nov 13, 2025 | S | 5,000 | $46.50 | Sale −$232,500 | 1,933 | No | Form 4 |
| Gold Alexander M | Nov 12, 2025 | Nov 13, 2025 | S | 1,933 | $47.28 | Sale −$91,392 | not reported | No | Form 4 |
| Gold Alexander M | Nov 12, 2025 | Nov 13, 2025 | M · derivative | 6,933 | $10.20 | $70,717 | 10,967 | No | Form 4 |
| Gold Alexander M | Nov 11, 2025 | Nov 13, 2025 | M | 15,000 | $10.20 | $153,000 | 15,000 | No | Form 4 |
| Gold Alexander M | Nov 11, 2025 | Nov 13, 2025 | S | 10,000 | $42.43 | Sale −$424,300 | 5,000 | No | Form 4 |
| Gold Alexander M | Nov 11, 2025 | Nov 13, 2025 | S | 5,000 | $47.08 | Sale −$235,400 | not reported | No | Form 4 |
| Gold Alexander M | Nov 11, 2025 | Nov 13, 2025 | M · derivative | 15,000 | $10.20 | $153,000 | 17,900 | No | Form 4 |
| Congleton JonChief Executive Officer | Nov 11, 2025 | Nov 13, 2025 | S | 12,806 | $41.64 | Sale −$533,242 | 818,499 | No | Form 4 |
| Congleton JonChief Executive Officer | Nov 11, 2025 | Nov 13, 2025 | S | 8,862 | $42.31 | Sale −$374,951 | 809,637 | No | Form 4 |
| Congleton JonChief Executive Officer | Nov 11, 2025 | Nov 13, 2025 | S | 4,000 | $43.50 | Sale −$174,000 | 805,637 | No | Form 4 |
| Congleton JonChief Executive Officer | Nov 11, 2025 | Nov 13, 2025 | S | 29,207 | $45.20 | Sale −$1,320,156 | 776,430 | No | Form 4 |
| Congleton JonChief Executive Officer | Nov 11, 2025 | Nov 13, 2025 | S | 112,275 | $45.83 | Sale −$5,145,563 | 664,155 | No | Form 4 |
| Congleton JonChief Executive Officer | Nov 11, 2025 | Nov 13, 2025 | S | 32,850 | $46.89 | Sale −$1,540,337 | 631,305 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Nov 11, 2025 | Nov 13, 2025 | M | 20,547 | $10.20 | $209,579 | 53,814 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Nov 11, 2025 | Nov 13, 2025 | M | 34,414 | $16.00 | $550,624 | 88,228 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Nov 11, 2025 | Nov 13, 2025 | M | 44,079 | $14.25 | $628,126 | 132,307 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Nov 11, 2025 | Nov 13, 2025 | M | 6,613 | $15.44 | $102,105 | 138,920 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Nov 11, 2025 | Nov 13, 2025 | S | 1,015 | $42.00 | Sale −$42,630 | 137,905 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Nov 11, 2025 | Nov 13, 2025 | S | 11,295 | $41.87 | Sale −$472,922 | 126,610 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Nov 11, 2025 | Nov 13, 2025 | S | 1,561 | $42.68 | Sale −$66,623 | 125,049 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Nov 11, 2025 | Nov 13, 2025 | S | 12,952 | $41.65 | Sale −$539,451 | 112,097 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Nov 11, 2025 | Nov 13, 2025 | S | 8,485 | $42.34 | Sale −$359,255 | 103,612 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Nov 11, 2025 | Nov 13, 2025 | S | 4,142 | $43.50 | Sale −$180,177 | 99,470 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Nov 11, 2025 | Nov 13, 2025 | S | 8,456 | $45.18 | Sale −$382,042 | 91,014 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Nov 11, 2025 | Nov 13, 2025 | S | 38,900 | $45.93 | Sale −$1,786,677 | 52,114 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Nov 11, 2025 | Nov 13, 2025 | S | 32,718 | $46.88 | Sale −$1,533,820 | 19,396 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Nov 11, 2025 | Nov 13, 2025 | M · derivative | 20,547 | $10.20 | $209,579 | 135,674 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Nov 11, 2025 | Nov 13, 2025 | M · derivative | 34,414 | $16.00 | $550,624 | 20,662 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Nov 11, 2025 | Nov 13, 2025 | M · derivative | 44,079 | $14.25 | $628,126 | 91,592 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Nov 11, 2025 | Nov 13, 2025 | M · derivative | 6,613 | $15.44 | $102,105 | 4,888 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Oct 15, 2025 | Oct 15, 2025 | S | 10,369 | $43.01 | Sale −$445,971 | 71,155 | Yes | Form 4 |
| Congleton JonChief Executive Officer | Oct 13, 2025 | Oct 15, 2025 | S | 13,548 | $42.63 | Sale −$577,551 | 832,857 | Yes | Form 4 |
| Congleton JonChief Executive Officer | Oct 13, 2025 | Oct 15, 2025 | S | 1,552 | $43.03 | Sale −$66,783 | 831,305 | Yes | Form 4 |
| Levy Adam ScottCFO and Secretary | Oct 13, 2025 | Oct 15, 2025 | S | 7,366 | $41.90 | Sale −$308,635 | 120,257 | Yes | Form 4 |
| Levy Adam ScottCFO and Secretary | Oct 13, 2025 | Oct 15, 2025 | S | 3,392 | $42.26 | Sale −$143,346 | 116,865 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Sep 15, 2025 | Sep 16, 2025 | S | 9,302 | $35.90 | Sale −$333,942 | 83,589 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Sep 15, 2025 | Sep 16, 2025 | S | 2,065 | $36.47 | Sale −$75,311 | 81,524 | Yes | Form 4 |
| Ra Capital Management, L.P. | Sep 4, 2025 | Sep 8, 2025 | P | 1,176,470 | $25.50 | Purchase +$29,999,985 | 5,456,521 | No | Form 4 |
| Akkaraju Srinivas | Sep 4, 2025 | Sep 8, 2025 | P | 588,235 | $25.50 | Purchase +$14,999,993 | 588,235 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Aug 13, 2025 | Aug 14, 2025 | S | 11,365 | $12.93 | Sale −$146,949 | 92,891 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Aug 12, 2025 | Aug 14, 2025 | M | 6,349 | $1.08 | $6,857 | 104,256 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Aug 12, 2025 | Aug 14, 2025 | M · derivative | 6,349 | $1.08 | $6,857 | 82,531 | Yes | Form 4 |
| Levy Adam ScottCFO and Secretary | Jul 30, 2025 | Jul 30, 2025 | S | 51,500 | $14.70 | Sale −$757,050 | 141,359 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Jul 30, 2025 | Jul 30, 2025 | S | 8,425 | $15.10 | Sale −$127,218 | 132,934 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Jul 29, 2025 | Jul 30, 2025 | S | 807 | $14.00 | Sale −$11,298 | 192,859 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Jul 28, 2025 | Jul 30, 2025 | S | 12,946 | $14.04 | Sale −$181,762 | 193,666 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 14, 2025 | Jul 15, 2025 | M | 6,349 | $1.08 | $6,857 | 109,273 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 14, 2025 | Jul 15, 2025 | S | 11,366 | $14.59 | Sale −$165,830 | 97,907 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 14, 2025 | Jul 15, 2025 | M · derivative | 6,349 | $1.08 | $6,857 | 88,880 | Yes | Form 4 |
| Levy Adam ScottCFO and Secretary | Jul 11, 2025 | Jul 15, 2025 | S | 10,758 | $14.45 | Sale −$155,453 | 206,612 | Yes | Form 4 |
| Congleton JonChief Executive Officer | Jul 11, 2025 | Jul 15, 2025 | S | 15,884 | $14.51 | Sale −$230,477 | 846,405 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jun 13, 2025 | Jun 16, 2025 | S | 11,366 | $14.60 | Sale −$165,944 | 101,651 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jun 12, 2025 | Jun 16, 2025 | M | 6,348 | $1.08 | $6,856 | 113,017 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jun 12, 2025 | Jun 16, 2025 | M · derivative | 6,348 | $1.08 | $6,856 | 95,229 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | May 14, 2025 | May 15, 2025 | S | 11,366 | $15.29 | Sale −$173,786 | 106,669 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | May 12, 2025 | May 13, 2025 | M | 6,349 | $1.08 | $6,857 | 118,035 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | May 12, 2025 | May 13, 2025 | M · derivative | 6,349 | $1.08 | $6,857 | 101,577 | Yes | Form 4 |
| Slingsby Brian Taylor | Mar 13, 2025 | Apr 25, 2025 | P | 259,259 | $13.50 | Purchase +$3,499,997 | 8,903,838 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 14, 2025 | Apr 15, 2025 | M | 6,348 | $1.08 | $6,856 | 123,052 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 14, 2025 | Apr 15, 2025 | S | 2,966 | $13.69 | Sale −$40,605 | 120,086 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 14, 2025 | Apr 15, 2025 | S | 8,400 | $14.83 | Sale −$124,572 | 111,686 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 14, 2025 | Apr 15, 2025 | M · derivative | 6,348 | $1.08 | $6,856 | 107,926 | Yes | Form 4 |
| Congleton JonChief Executive Officer | Apr 11, 2025 | Apr 15, 2025 | S | 15,319 | $12.19 | Sale −$186,739 | 862,289 | Yes | Form 4 |
| Levy Adam ScottCFO and Secretary | Apr 11, 2025 | Apr 15, 2025 | S | 10,757 | $12.06 | Sale −$129,729 | 215,340 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 1, 2025 | Apr 3, 2025 | M | 1,606 | $1.08 | $1,734 | 172,475 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 1, 2025 | Apr 3, 2025 | S | 30,574 | $15.00 | Sale −$458,610 | 141,901 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 1, 2025 | Apr 3, 2025 | S | 2,791 | $16.02 | Sale −$44,712 | 139,110 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 1, 2025 | Apr 3, 2025 | S | 22,406 | $16.77 | Sale −$375,749 | 116,704 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 1, 2025 | Apr 3, 2025 | M · derivative | 1,606 | $1.08 | $1,734 | 114,274 | Yes | Form 4 |
| RA Capital Nexus Fund III, L.P. | Mar 13, 2025 | Mar 17, 2025 | P | 1,296,296 | $13.50 | Purchase +$17,499,996 | 4,280,051 | No | Form 4 |
| Akkaraju Srinivas | Mar 13, 2025 | Mar 17, 2025 | P | 600,000 | $13.50 | Purchase +$8,100,000 | 5,674,916 | No | Form 4 |
| Samsara BioCapital, L.P. | Mar 13, 2025 | Mar 17, 2025 | P | 600,000 | $13.50 | Purchase +$8,100,000 | 5,674,916 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 12, 2025 | Mar 13, 2025 | M | 6,349 | $1.08 | $6,857 | 170,869 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 12, 2025 | Mar 13, 2025 | M · derivative | 6,349 | $1.08 | $6,857 | 115,880 | No | Form 4 |
| Ra Capital Management, L.P. | Feb 13, 2025 | Feb 24, 2025 | A · derivative | 32,900 | $10.20 | $335,580 | 32,900 | No | Form 4 |
| Sblendorio Glenn | Feb 13, 2025 | Feb 24, 2025 | A · derivative | 32,900 | $10.20 | $335,580 | 32,900 | No | Form 4 |
| Karydas Daphne | Feb 13, 2025 | Feb 24, 2025 | A · derivative | 32,900 | $10.20 | $335,580 | 32,900 | No | Form 4 |
| Congleton JonChief Executive Officer | Feb 13, 2025 | Feb 24, 2025 | A · derivative | 570,000 | $10.20 | $5,814,000 | 570,000 | No | Form 4 |
| Gold Alexander M | Feb 13, 2025 | Feb 24, 2025 | A · derivative | 32,900 | $10.20 | $335,580 | 32,900 | No | Form 4 |
| DiRocco Derek | Feb 13, 2025 | Feb 24, 2025 | A · derivative | 32,900 | $10.20 | $335,580 | 32,900 | No | Form 4 |
| Catalys Pacific Fund, LP | Feb 13, 2025 | Feb 24, 2025 | A · derivative | 32,900 | $10.20 | $335,580 | 32,900 | No | Form 4 |
| Catalys Pacific Fund, LP | Feb 13, 2025 | Feb 24, 2025 | J · derivative | 32,900 | $10.20 | $335,580 | not reported | No | Form 4 |
| Catalys Pacific Fund, LP | Feb 13, 2025 | Feb 24, 2025 | J · derivative | 32,900 | $10.20 | $335,580 | 32,900 | No | Form 4 |
| Samsara BioCapital, L.P. | Feb 13, 2025 | Feb 24, 2025 | A · derivative | 32,900 | $10.20 | $335,580 | 32,900 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 13, 2025 | Feb 24, 2025 | A · derivative | 170,000 | $10.20 | $1,734,000 | 170,000 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Feb 13, 2025 | Feb 24, 2025 | A · derivative | 170,000 | $10.20 | $1,734,000 | 170,000 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 12, 2025 | Feb 13, 2025 | M | 6,348 | $1.08 | $6,856 | 164,520 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 12, 2025 | Feb 13, 2025 | M · derivative | 6,348 | $1.08 | $6,856 | 122,229 | No | Form 4 |
| Congleton JonChief Executive Officer | Jan 13, 2025 | Jan 15, 2025 | S | 18,333 | $9.06 | Sale −$166,097 | 877,608 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 13, 2025 | Jan 15, 2025 | M | 5,018 | $0.54 | $2,710 | 151,823 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 13, 2025 | Jan 15, 2025 | M | 6,349 | $1.08 | $6,857 | 158,172 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 13, 2025 | Jan 15, 2025 | M · derivative | 5,018 | $0.54 | $2,710 | not reported | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 13, 2025 | Jan 15, 2025 | M · derivative | 6,349 | $1.08 | $6,857 | 128,577 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Jan 13, 2025 | Jan 15, 2025 | S | 10,657 | $9.09 | Sale −$96,872 | 226,197 | Yes | Form 4 |
| Levy Adam ScottCFO and Secretary | Jan 13, 2025 | Jan 15, 2025 | S | 100 | $9.63 | Sale −$963 | 226,097 | Yes | Form 4 |
| Slingsby Brian Taylor | May 22, 2024 | Jan 7, 2025 | J · derivative | 22,000 | $12.52 | $275,440 | not reported | No | Form 4 |
| Slingsby Brian Taylor | May 22, 2024 | Jan 7, 2025 | J · derivative | 22,000 | $12.52 | $275,440 | 22,000 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Dec 11, 2024 | Dec 13, 2024 | M | 5,017 | $0.54 | $2,709 | 146,008 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Dec 11, 2024 | Dec 13, 2024 | M · derivative | 5,017 | $0.54 | $2,709 | 5,018 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Nov 11, 2024 | Nov 12, 2024 | M | 5,017 | $0.54 | $2,709 | 140,991 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Nov 11, 2024 | Nov 12, 2024 | M | 5,026 | $1.08 | $5,428 | 146,017 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Nov 11, 2024 | Nov 12, 2024 | S | 5,026 | $15.00 | Sale −$75,390 | 140,991 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Nov 11, 2024 | Nov 12, 2024 | M · derivative | 5,017 | $0.54 | $2,709 | 10,035 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Nov 11, 2024 | Nov 12, 2024 | M · derivative | 5,026 | $1.08 | $5,428 | 134,926 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Nov 6, 2024 | Nov 8, 2024 | M | 25,482 | $1.08 | $27,521 | 161,456 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Nov 6, 2024 | Nov 8, 2024 | S | 25,482 | $15.03 | Sale −$382,994 | 135,974 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Nov 6, 2024 | Nov 8, 2024 | M · derivative | 25,482 | $1.08 | $27,521 | 139,952 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Oct 14, 2024 | Oct 15, 2024 | M | 5,352 | $1.08 | $5,780 | 135,974 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Oct 14, 2024 | Oct 15, 2024 | M · derivative | 5,352 | $1.08 | $5,780 | 165,434 | No | Form 4 |
| Congleton JonChief Executive Officer | Oct 11, 2024 | Oct 15, 2024 | S | 15,271 | $13.52 | Sale −$206,464 | 895,941 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Oct 11, 2024 | Oct 15, 2024 | M | 5,017 | $0.54 | $2,709 | 130,622 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Oct 11, 2024 | Oct 15, 2024 | M · derivative | 5,017 | $0.54 | $2,709 | 15,052 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Oct 11, 2024 | Oct 15, 2024 | S | 10,757 | $13.57 | Sale −$145,972 | 236,854 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Sep 12, 2024 | Sep 12, 2024 | M | 6,349 | $1.08 | $6,857 | 125,605 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Sep 12, 2024 | Sep 12, 2024 | M · derivative | 6,349 | $1.08 | $6,857 | 170,786 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Sep 11, 2024 | Sep 12, 2024 | M | 5,018 | $0.54 | $2,710 | 119,256 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Sep 11, 2024 | Sep 12, 2024 | M · derivative | 5,018 | $0.54 | $2,710 | 20,069 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Aug 12, 2024 | Aug 13, 2024 | M | 5,017 | $0.54 | $2,709 | 107,890 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Aug 12, 2024 | Aug 13, 2024 | M | 6,348 | $1.08 | $6,856 | 114,238 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Aug 12, 2024 | Aug 13, 2024 | M · derivative | 5,017 | $0.54 | $2,709 | 25,087 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Aug 12, 2024 | Aug 13, 2024 | M · derivative | 6,348 | $1.08 | $6,856 | 177,135 | No | Form 4 |
| Slingsby Brian Taylor | Jul 24, 2024 | Jul 26, 2024 | S | 550,000 | $13.05 | Sale −$7,177,500 | 8,644,579 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 16, 2024 | Jul 18, 2024 | M | 525 | $1.08 | $567 | 103,398 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 16, 2024 | Jul 18, 2024 | S | 525 | $15.00 | Sale −$7,875 | 102,873 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 16, 2024 | Jul 18, 2024 | M · derivative | 525 | $1.08 | $567 | 183,483 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 12, 2024 | Jul 12, 2024 | M | 6,349 | $1.08 | $6,857 | 102,873 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 12, 2024 | Jul 12, 2024 | M · derivative | 6,349 | $1.08 | $6,857 | 184,008 | No | Form 4 |
| Congleton JonChief Executive Officer | Jul 11, 2024 | Jul 12, 2024 | S | 15,746 | $13.34 | Sale −$210,052 | 911,212 | Yes | Form 4 |
| Levy Adam ScottCFO and Secretary | Jul 11, 2024 | Jul 12, 2024 | S | 10,757 | $13.14 | Sale −$141,347 | 247,611 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 11, 2024 | Jul 12, 2024 | M | 5,017 | $0.54 | $2,709 | 96,524 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Jul 11, 2024 | Jul 12, 2024 | M · derivative | 5,017 | $0.54 | $2,709 | 30,104 | No | Form 4 |
| Congleton JonChief Executive Officer | Jun 20, 2024 | Jun 20, 2024 | S | 14,940 | $11.73 | Sale −$175,246 | 926,958 | Yes | Form 4 |
| Congleton JonChief Executive Officer | Jun 18, 2024 | Jun 20, 2024 | S | 16,607 | $11.99 | Sale −$199,118 | 941,898 | Yes | Form 4 |
| Congleton JonChief Executive Officer | Jun 17, 2024 | Jun 20, 2024 | S | 17,766 | $12.25 | Sale −$217,634 | 958,505 | Yes | Form 4 |
| Gold Alexander M | Jun 13, 2024 | Jun 17, 2024 | A · derivative | 44,000 | $12.69 | $558,360 | 44,000 | No | Form 4 |
| Congleton JonChief Executive Officer | Jun 14, 2024 | Jun 14, 2024 | S | 16,229 | $12.52 | Sale −$203,187 | 976,271 | Yes | Form 4 |
| Congleton JonChief Executive Officer | Jun 13, 2024 | Jun 14, 2024 | S | 39,961 | $12.74 | Sale −$509,103 | 992,500 | Yes | Form 4 |
| Congleton JonChief Executive Officer | Jun 12, 2024 | Jun 14, 2024 | S | 16,607 | $12.77 | Sale −$212,071 | 1,032,461 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Jun 12, 2024 | Jun 13, 2024 | M | 6,349 | $1.08 | $6,857 | 89,729 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Jun 12, 2024 | Jun 13, 2024 | M · derivative | 6,349 | $1.08 | $6,857 | 190,357 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Jun 11, 2024 | Jun 13, 2024 | M | 5,017 | $0.54 | $2,709 | 83,380 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Jun 11, 2024 | Jun 13, 2024 | M · derivative | 5,017 | $0.54 | $2,709 | 35,121 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Jun 11, 2024 | Jun 13, 2024 | S | 96,815 | $12.94 | Sale −$1,252,786 | 255,462 | Yes | Form 4 |
| Kolchinsky Peter | May 22, 2024 | May 28, 2024 | A · derivative | 22,000 | $12.52 | $275,440 | 22,000 | No | Form 4 |
| Litzka Olivier | May 22, 2024 | May 23, 2024 | A · derivative | 22,000 | $12.52 | $275,440 | 22,000 | No | Form 4 |
| Catalys Pacific Fund, LP | May 22, 2024 | May 23, 2024 | A · derivative | 22,000 | $12.52 | $275,440 | 22,000 | No | Form 4 |
| Karydas Daphne | May 22, 2024 | May 23, 2024 | A · derivative | 22,000 | $12.52 | $275,440 | 22,000 | No | Form 4 |
| Akkaraju Srinivas | May 22, 2024 | May 23, 2024 | A · derivative | 22,000 | $12.52 | $275,440 | 22,000 | No | Form 4 |
| Sblendorio Glenn | May 22, 2024 | May 23, 2024 | A · derivative | 22,000 | $12.52 | $275,440 | 22,000 | No | Form 4 |
| DiRocco Derek | May 22, 2024 | May 23, 2024 | A · derivative | 22,000 | $12.52 | $275,440 | 22,000 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | May 13, 2024 | May 15, 2024 | M | 5,018 | $0.54 | $2,710 | 72,015 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | May 13, 2024 | May 15, 2024 | M | 6,348 | $1.08 | $6,856 | 78,363 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | May 13, 2024 | May 15, 2024 | M · derivative | 5,018 | $0.54 | $2,710 | 40,138 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | May 13, 2024 | May 15, 2024 | M · derivative | 6,348 | $1.08 | $6,856 | 196,706 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | May 9, 2024 | May 10, 2024 | M | 100 | $1.08 | $108 | 67,097 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | May 9, 2024 | May 10, 2024 | S | 100 | $15.00 | Sale −$1,500 | 66,997 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | May 9, 2024 | May 10, 2024 | M · derivative | 100 | $1.08 | $108 | 203,054 | Yes | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 12, 2024 | Apr 15, 2024 | M | 6,349 | $1.08 | $6,857 | 66,997 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 12, 2024 | Apr 15, 2024 | M · derivative | 6,349 | $1.08 | $6,857 | 203,154 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 11, 2024 | Apr 15, 2024 | M | 5,017 | $0.54 | $2,709 | 60,648 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Apr 11, 2024 | Apr 15, 2024 | M · derivative | 5,017 | $0.54 | $2,709 | 45,156 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 12, 2024 | Mar 13, 2024 | M | 6,348 | $1.08 | $6,856 | 55,631 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 12, 2024 | Mar 13, 2024 | M · derivative | 6,348 | $1.08 | $6,856 | 209,503 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 11, 2024 | Mar 13, 2024 | M | 5,017 | $0.54 | $2,709 | 49,283 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Mar 11, 2024 | Mar 13, 2024 | M · derivative | 5,017 | $0.54 | $2,709 | 50,173 | No | Form 4 |
| Congleton JonChief Executive Officer | Feb 13, 2024 | Feb 15, 2024 | A · derivative | 425,000 | $14.25 | $6,056,250 | 425,000 | No | Form 4 |
| Levy Adam ScottCFO and Secretary | Feb 13, 2024 | Feb 15, 2024 | A · derivative | 200,000 | $14.25 | $2,850,000 | 200,000 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 13, 2024 | Feb 15, 2024 | A · derivative | 200,000 | $14.25 | $2,850,000 | 200,000 | No | Form 4 |
| Ra Capital Management, L.P. | Feb 12, 2024 | Feb 14, 2024 | A | 1,672,508 | $13.50 | $22,578,858 | 2,983,755 | No | Form 4 |
| Ra Capital Management, L.P. | Feb 12, 2024 | Feb 14, 2024 | A · derivative | 549,755 | $13.50 | $7,421,693 | 549,755 | No | Form 4 |
| Samsara BioCapital, L.P. | Feb 12, 2024 | Feb 14, 2024 | P | 555,555 | $13.50 | Purchase +$7,499,993 | 5,074,916 | No | Form 4 |
| Akkaraju Srinivas | Feb 12, 2024 | Feb 14, 2024 | A | 555,555 | $13.50 | $7,499,993 | 5,074,916 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 12, 2024 | Feb 13, 2024 | M | 5,017 | $0.54 | $2,709 | 37,917 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 12, 2024 | Feb 13, 2024 | M | 6,349 | $1.08 | $6,857 | 44,266 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 12, 2024 | Feb 13, 2024 | M · derivative | 5,017 | $0.54 | $2,709 | 55,190 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Feb 12, 2024 | Feb 13, 2024 | M · derivative | 6,349 | $1.08 | $6,857 | 215,851 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 12, 2024 | Jan 12, 2024 | M | 6,348 | $1.08 | $6,856 | 32,900 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 12, 2024 | Jan 12, 2024 | M · derivative | 6,348 | $1.08 | $6,856 | 222,200 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 11, 2024 | Jan 12, 2024 | M | 5,017 | $0.54 | $2,709 | 26,552 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Jan 11, 2024 | Jan 12, 2024 | M · derivative | 5,017 | $0.54 | $2,709 | 60,207 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Dec 11, 2023 | Dec 12, 2023 | M | 5,018 | $0.54 | $2,710 | 20,069 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Dec 11, 2023 | Dec 12, 2023 | M · derivative | 5,018 | $0.54 | $2,710 | 65,224 | No | Form 4 |
| Congleton JonChief Executive Officer | Nov 22, 2023 | Nov 27, 2023 | P | 4,250 | $5.97 | Purchase +$25,373 | 1,049,068 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Nov 13, 2023 | Nov 14, 2023 | M | 5,017 | $0.54 | $2,709 | 15,051 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Nov 13, 2023 | Nov 14, 2023 | M · derivative | 5,017 | $0.54 | $2,709 | 70,242 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Nov 3, 2023 | Nov 7, 2023 | M | 10,034 | $0.54 | $5,418 | 10,034 | No | Form 4 |
| Rodman David MalcomChief Medical Officer | Nov 3, 2023 | Nov 7, 2023 | M · derivative | 10,034 | $0.54 | $5,418 | 75,259 | No | Form 4 |