PLRXPLIANT THERAPEUTICS, INC.
- Market cap
- $53.48M
- as of 2026-10-23
- Latest close
- $0.86
- as of 2026-10-23
- Sector
- Healthcare
- as of 2026-10-24
- Industry
- Biotechnology
- as of 2026-10-24
Cluster
No cluster in the last 90 days under the default rule (14d · ≥2 insiders · all roles).
Form 4 historysince 2024-01-19
| Insider | Traded | Filed | Type | Shares | Price | Value | Owned after | 10b5-1 plan | Filing |
|---|---|---|---|---|---|---|---|---|---|
| Raben DavidChief Medical Officer | Oct 1 | Oct 2 | A · derivative | 575,000 | $1.05 | $603,750 | 575,000 | No | Form 4 |
| Iannone Robert | Jul 9 | Jul 13 | A · derivative | 60,000 | $1.13 | $67,800 | 60,000 | No | Form 4 |
| Borellini Flavia | Jul 9 | Jul 13 | A · derivative | 60,000 | $1.13 | $67,800 | 60,000 | No | Form 4 |
| Cline Darren S | Jun 11 | Jun 12 | A · derivative | 70,000 | $1.14 | $79,800 | 70,000 | No | Form 4 |
| Huh Hoyoung | Jun 11 | Jun 12 | A · derivative | 70,000 | $1.14 | $79,800 | 70,000 | No | Form 4 |
| Curnutte John T | Jun 11 | Jun 12 | A · derivative | 70,000 | $1.14 | $79,800 | 70,000 | No | Form 4 |
| Krognes Steve E. | Jun 11 | Jun 12 | A · derivative | 70,000 | $1.14 | $79,800 | 70,000 | No | Form 4 |
| MCCOURT Thomas A | Jun 11 | Jun 12 | A · derivative | 70,000 | $1.14 | $79,800 | 70,000 | No | Form 4 |
| Crowell Gayle A | Jun 11 | Jun 12 | A · derivative | 70,000 | $1.14 | $79,800 | 70,000 | No | Form 4 |
| Cheung LilyChief Human Resource Officer | Apr 17 | Apr 17 | D · derivative | 123,000 | $21.94 | $2,698,620 | not reported | No | Form 4 |
| Cheung LilyChief Human Resource Officer | Apr 17 | Apr 17 | A · derivative | 123,000 | $1.33 | $163,590 | 123,000 | No | Form 4 |
| Cheung LilyChief Human Resource Officer | Apr 17 | Apr 17 | D · derivative | 52,000 | $17.44 | $906,880 | not reported | No | Form 4 |
| Cheung LilyChief Human Resource Officer | Apr 17 | Apr 17 | A · derivative | 52,000 | $1.33 | $69,160 | 52,000 | No | Form 4 |
| Cheung LilyChief Human Resource Officer | Apr 17 | Apr 17 | D · derivative | 51,750 | $11.14 | $576,495 | not reported | No | Form 4 |
| Cheung LilyChief Human Resource Officer | Apr 17 | Apr 17 | A · derivative | 51,750 | $1.33 | $68,828 | 51,750 | No | Form 4 |
| Coulie BernardPresident and CEO | Apr 17 | Apr 17 | D · derivative | 146,841 | $2.08 | $305,429 | not reported | No | Form 4 |
| Coulie BernardPresident and CEO | Apr 17 | Apr 17 | A · derivative | 146,841 | $1.33 | $195,299 | 146,841 | No | Form 4 |
| Coulie BernardPresident and CEO | Apr 17 | Apr 17 | D · derivative | 327,262 | $6.22 | $2,035,570 | not reported | No | Form 4 |
| Coulie BernardPresident and CEO | Apr 17 | Apr 17 | A · derivative | 327,262 | $1.33 | $435,258 | 327,262 | No | Form 4 |
| Coulie BernardPresident and CEO | Apr 17 | Apr 17 | D · derivative | 250,000 | $26.50 | $6,625,000 | not reported | No | Form 4 |
| Coulie BernardPresident and CEO | Apr 17 | Apr 17 | A · derivative | 250,000 | $1.33 | $332,500 | 250,000 | No | Form 4 |
| Coulie BernardPresident and CEO | Apr 17 | Apr 17 | D · derivative | 440,000 | $11.86 | $5,218,400 | not reported | No | Form 4 |
| Coulie BernardPresident and CEO | Apr 17 | Apr 17 | A · derivative | 440,000 | $1.33 | $585,200 | 440,000 | No | Form 4 |
| Coulie BernardPresident and CEO | Apr 17 | Apr 17 | D · derivative | 206,300 | $34.65 | $7,148,295 | not reported | No | Form 4 |
| Coulie BernardPresident and CEO | Apr 17 | Apr 17 | A · derivative | 206,300 | $1.33 | $274,379 | 206,300 | No | Form 4 |
| Coulie BernardPresident and CEO | Apr 17 | Apr 17 | D · derivative | 256,300 | $17.44 | $4,469,872 | not reported | No | Form 4 |
| Coulie BernardPresident and CEO | Apr 17 | Apr 17 | A · derivative | 256,300 | $1.33 | $340,879 | 256,300 | No | Form 4 |
| Coulie BernardPresident and CEO | Apr 17 | Apr 17 | D · derivative | 325,000 | $11.14 | $3,620,500 | not reported | No | Form 4 |
| Coulie BernardPresident and CEO | Apr 17 | Apr 17 | A · derivative | 325,000 | $1.33 | $432,250 | 325,000 | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | Apr 17 | Apr 17 | D · derivative | 76,047 | $2.08 | $158,178 | not reported | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | Apr 17 | Apr 17 | A · derivative | 76,047 | $1.33 | $101,143 | 76,047 | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | Apr 17 | Apr 17 | D · derivative | 18,198 | $6.22 | $113,192 | not reported | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | Apr 17 | Apr 17 | A · derivative | 18,198 | $1.33 | $24,203 | 18,198 | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | Apr 17 | Apr 17 | D · derivative | 74,250 | $26.50 | $1,967,625 | not reported | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | Apr 17 | Apr 17 | A · derivative | 74,250 | $1.33 | $98,753 | 74,250 | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | Apr 17 | Apr 17 | D · derivative | 124,000 | $11.86 | $1,470,640 | not reported | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | Apr 17 | Apr 17 | A · derivative | 124,000 | $1.33 | $164,920 | 124,000 | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | Apr 17 | Apr 17 | D · derivative | 76,200 | $34.65 | $2,640,330 | not reported | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | Apr 17 | Apr 17 | A · derivative | 76,200 | $1.33 | $101,346 | 76,200 | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | Apr 17 | Apr 17 | D · derivative | 110,500 | $17.44 | $1,927,120 | not reported | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | Apr 17 | Apr 17 | A · derivative | 110,500 | $1.33 | $146,965 | 110,500 | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | Apr 17 | Apr 17 | D · derivative | 113,300 | $11.14 | $1,262,162 | not reported | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | Apr 17 | Apr 17 | A · derivative | 113,300 | $1.33 | $150,689 | 113,300 | No | Form 4 |
| Kuo MinnieChief Operating Officer | Apr 17 | Apr 17 | D · derivative | 150,000 | $16.18 | $2,427,000 | not reported | No | Form 4 |
| Kuo MinnieChief Operating Officer | Apr 17 | Apr 17 | A · derivative | 150,000 | $1.33 | $199,500 | 150,000 | No | Form 4 |
| Kuo MinnieChief Operating Officer | Apr 17 | Apr 17 | D · derivative | 40,000 | $17.44 | $697,600 | not reported | No | Form 4 |
| Kuo MinnieChief Operating Officer | Apr 17 | Apr 17 | A · derivative | 40,000 | $1.33 | $53,200 | 40,000 | No | Form 4 |
| Kuo MinnieChief Operating Officer | Apr 17 | Apr 17 | D · derivative | 55,200 | $11.14 | $614,928 | not reported | No | Form 4 |
| Kuo MinnieChief Operating Officer | Apr 17 | Apr 17 | A · derivative | 55,200 | $1.33 | $73,416 | 55,200 | No | Form 4 |
| Coulie BernardPresident and CEO | Jan 22 | Jan 26 | A · derivative | 1,230,000 | $1.30 | $1,599,000 | 1,230,000 | No | Form 4 |
| Cheung LilyChief Human Resource Officer | Jan 22 | Jan 26 | A · derivative | 300,000 | $1.30 | $390,000 | 300,000 | No | Form 4 |
| Kuo MinnieChief Operating Officer | Jan 22 | Jan 26 | A · derivative | 300,000 | $1.30 | $390,000 | 300,000 | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | Jan 22 | Jan 26 | A · derivative | 400,000 | $1.30 | $520,000 | 400,000 | No | Form 4 |
| Kuo MinnieChief Operating Officer | Jan 20 | Jan 22 | S | 6,917 | $1.28 | Sale −$8,854 | 37,806 | Yes | Form 4 |
| Coulie BernardPresident and CEO | Jan 20 | Jan 22 | S | 89,375 | $1.28 | Sale −$114,400 | 505,601 | Yes | Form 4 |
| Cheung LilyChief Human Resource Officer | Jan 20 | Jan 22 | S | 7,534 | $1.28 | Sale −$9,644 | 44,847 | Yes | Form 4 |
| Cummings Keith LamontChief Financial Officer | Jan 20 | Jan 22 | S | 24,002 | $1.28 | Sale −$30,723 | 297,214 | Yes | Form 4 |
| Crowell Gayle A | Jun 5, 2025 | Jun 9, 2025 | A · derivative | 30,000 | $1.61 | $48,300 | 30,000 | No | Form 4 |
| Huh Hoyoung | Jun 5, 2025 | Jun 9, 2025 | A · derivative | 30,000 | $1.61 | $48,300 | 30,000 | No | Form 4 |
| Pyott David E I | Jun 5, 2025 | Jun 9, 2025 | A · derivative | 30,000 | $1.61 | $48,300 | 30,000 | No | Form 4 |
| Cline Darren S | Jun 5, 2025 | Jun 9, 2025 | A · derivative | 30,000 | $1.61 | $48,300 | 30,000 | No | Form 4 |
| Krognes Steve E. | Jun 5, 2025 | Jun 9, 2025 | A · derivative | 30,000 | $1.61 | $48,300 | 30,000 | No | Form 4 |
| Curnutte John T | Jun 5, 2025 | Jun 9, 2025 | A · derivative | 30,000 | $1.61 | $48,300 | 30,000 | No | Form 4 |
| MCCOURT Thomas A | Jun 5, 2025 | Jun 9, 2025 | A · derivative | 30,000 | $1.61 | $48,300 | 30,000 | No | Form 4 |
| Knobil Katharine | Jun 5, 2025 | Jun 9, 2025 | A · derivative | 30,000 | $1.61 | $48,300 | 30,000 | No | Form 4 |
| Bruhn Suzanne Louise | Jun 5, 2025 | Jun 9, 2025 | A · derivative | 30,000 | $1.61 | $48,300 | 30,000 | No | Form 4 |
| Coulie BernardPresident and CEO | Jan 23, 2025 | Jan 27, 2025 | A | 162,500 | $0.00 | $0 | 593,017 | No | Form 4 |
| Coulie BernardPresident and CEO | Jan 23, 2025 | Jan 27, 2025 | A · derivative | 325,000 | $11.14 | $3,620,500 | 325,000 | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | Jan 23, 2025 | Jan 27, 2025 | A | 56,650 | $0.00 | $0 | 319,258 | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | Jan 23, 2025 | Jan 27, 2025 | A · derivative | 113,300 | $11.14 | $1,262,162 | 113,300 | No | Form 4 |
| Lefebvre EricChief Medical Officer | Jan 23, 2025 | Jan 27, 2025 | A | 45,650 | $0.00 | $0 | 240,224 | No | Form 4 |
| Lefebvre EricChief Medical Officer | Jan 23, 2025 | Jan 27, 2025 | A · derivative | 91,300 | $11.14 | $1,017,082 | 91,300 | No | Form 4 |
| Hull HansChief Business Officer | Jan 23, 2025 | Jan 27, 2025 | A | 40,150 | $0.00 | $0 | 251,708 | No | Form 4 |
| Hull HansChief Business Officer | Jan 23, 2025 | Jan 27, 2025 | A · derivative | 80,300 | $11.14 | $894,542 | 80,300 | No | Form 4 |
| Ouimette MikeGeneral Counsel & Corp. Sec'y | Jan 23, 2025 | Jan 27, 2025 | A | 35,000 | $0.00 | $0 | 105,544 | No | Form 4 |
| Ouimette MikeGeneral Counsel & Corp. Sec'y | Jan 23, 2025 | Jan 27, 2025 | A · derivative | 70,000 | $11.14 | $779,800 | 70,000 | No | Form 4 |
| Cheung LilyChief Human Resource Officer | Jan 23, 2025 | Jan 27, 2025 | A | 25,875 | $0.00 | $0 | 50,425 | No | Form 4 |
| Cheung LilyChief Human Resource Officer | Jan 23, 2025 | Jan 27, 2025 | A · derivative | 51,750 | $11.14 | $576,495 | 51,750 | No | Form 4 |
| Ouimette MikeGeneral Counsel & Corp. Sec'y | Jan 22, 2025 | Jan 22, 2025 | S | 10,230 | $10.99 | Sale −$112,428 | 70,544 | Yes | Form 4 |
| Ouimette MikeGeneral Counsel & Corp. Sec'y | Jan 17, 2025 | Jan 22, 2025 | S | 13,270 | $11.20 | Sale −$148,624 | 80,774 | Yes | Form 4 |
| Cheung LilyChief Human Resource Officer | Jan 17, 2025 | Jan 22, 2025 | S | 3,740 | $11.20 | Sale −$41,888 | 24,550 | Yes | Form 4 |
| Lefebvre EricChief Medical Officer | Jan 17, 2025 | Jan 22, 2025 | S | 18,478 | $11.20 | Sale −$206,954 | 194,574 | Yes | Form 4 |
| Hull HansChief Business Officer | Jan 17, 2025 | Jan 22, 2025 | S | 15,936 | $11.20 | Sale −$178,483 | 211,558 | Yes | Form 4 |
| Cummings Keith LamontChief Financial Officer | Jan 17, 2025 | Jan 22, 2025 | S | 20,148 | $11.20 | Sale −$225,658 | 262,608 | Yes | Form 4 |
| Coulie BernardPresident and CEO | Jan 17, 2025 | Jan 22, 2025 | S | 52,419 | $11.20 | Sale −$587,093 | 430,517 | Yes | Form 4 |
| Ouimette MikeGeneral Counsel & Corp. Sec'y | Jul 10, 2024 | Jul 12, 2024 | S | 7,656 | $11.56 | Sale −$88,503 | 94,044 | Yes | Form 4 |
| Coulie BernardPresident and CEO | Jul 10, 2024 | Jul 12, 2024 | S | 38,710 | $11.56 | Sale −$447,488 | 482,936 | Yes | Form 4 |
| Cummings Keith LamontChief Financial Officer | Jul 10, 2024 | Jul 12, 2024 | S | 10,911 | $11.56 | Sale −$126,131 | 282,115 | Yes | Form 4 |
| Hull HansChief Business Officer | Jul 10, 2024 | Jul 12, 2024 | S | 9,900 | $11.56 | Sale −$114,444 | 227,494 | Yes | Form 4 |
| Lefebvre EricChief Medical Officer | Jul 10, 2024 | Jul 12, 2024 | S | 12,319 | $11.56 | Sale −$142,408 | 213,052 | Yes | Form 4 |
| Ouimette MikeGeneral Counsel & Corp. Sec'y | Jul 9, 2024 | Jul 11, 2024 | A | 14,954 | $0.00 | $0 | 101,700 | No | Form 4 |
| Coulie BernardPresident and CEO | Jul 9, 2024 | Jul 11, 2024 | A | 75,625 | $0.00 | $0 | 521,646 | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | Jul 9, 2024 | Jul 11, 2024 | A | 21,313 | $0.00 | $0 | 293,026 | No | Form 4 |
| Hull HansChief Business Officer | Jul 9, 2024 | Jul 11, 2024 | A | 19,337 | $0.00 | $0 | 237,394 | No | Form 4 |
| Lefebvre EricChief Medical Officer | Jul 9, 2024 | Jul 11, 2024 | A | 24,063 | $0.00 | $0 | 225,371 | No | Form 4 |
| Krognes Steve E. | Jun 13, 2024 | Jun 17, 2024 | A · derivative | 53,528 | $13.06 | $699,076 | 53,528 | No | Form 4 |
| Curnutte John T | Jun 13, 2024 | Jun 17, 2024 | A · derivative | 26,764 | $13.06 | $349,538 | 26,764 | No | Form 4 |
| Bruhn Suzanne Louise | Jun 13, 2024 | Jun 17, 2024 | A · derivative | 26,764 | $13.06 | $349,538 | 26,764 | No | Form 4 |
| Crowell Gayle A | Jun 13, 2024 | Jun 17, 2024 | A · derivative | 26,764 | $13.06 | $349,538 | 26,764 | No | Form 4 |
| Cline Darren S | Jun 13, 2024 | Jun 17, 2024 | A · derivative | 26,764 | $13.06 | $349,538 | 26,764 | No | Form 4 |
| Shah Smital | Jun 13, 2024 | Jun 17, 2024 | A · derivative | 26,764 | $13.06 | $349,538 | 26,764 | No | Form 4 |
| Pyott David E I | Jun 13, 2024 | Jun 17, 2024 | A · derivative | 26,764 | $13.06 | $349,538 | 26,764 | No | Form 4 |
| Huh Hoyoung | Jun 13, 2024 | Jun 17, 2024 | A · derivative | 26,764 | $13.06 | $349,538 | 26,764 | No | Form 4 |
| Knobil Katharine | Jun 13, 2024 | Jun 17, 2024 | A · derivative | 26,764 | $13.06 | $349,538 | 26,764 | No | Form 4 |
| MCCOURT Thomas A | Jun 13, 2024 | Jun 17, 2024 | A · derivative | 26,764 | $13.06 | $349,538 | 26,764 | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | May 2, 2024 | May 6, 2024 | M | 21,000 | $2.08 | $43,680 | 271,713 | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | May 2, 2024 | May 6, 2024 | M · derivative | 21,000 | $2.08 | $43,680 | 76,047 | No | Form 4 |
| Coulie BernardPresident and CEO | Jan 23, 2024 | Jan 24, 2024 | A | 128,150 | $0.00 | $0 | 444,532 | No | Form 4 |
| Coulie BernardPresident and CEO | Jan 23, 2024 | Jan 24, 2024 | A · derivative | 256,300 | $17.44 | $4,469,872 | 256,300 | No | Form 4 |
| Cheung LilyChief Human Resource Officer | Jan 23, 2024 | Jan 24, 2024 | A | 26,000 | $0.00 | $0 | 26,795 | No | Form 4 |
| Cheung LilyChief Human Resource Officer | Jan 23, 2024 | Jan 24, 2024 | A · derivative | 52,000 | $17.44 | $906,880 | 52,000 | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | Jan 23, 2024 | Jan 24, 2024 | A | 55,250 | $0.00 | $0 | 249,855 | No | Form 4 |
| Cummings Keith LamontChief Financial Officer | Jan 23, 2024 | Jan 24, 2024 | A · derivative | 110,500 | $17.44 | $1,927,120 | 110,500 | No | Form 4 |
| Ouimette MikeGeneral Counsel & Corp. Sec'y | Jan 23, 2024 | Jan 24, 2024 | A | 31,500 | $0.00 | $0 | 86,746 | No | Form 4 |
| Ouimette MikeGeneral Counsel & Corp. Sec'y | Jan 23, 2024 | Jan 24, 2024 | A · derivative | 63,000 | $17.44 | $1,098,720 | 63,000 | No | Form 4 |
| Hull HansChief Business Officer | Jan 23, 2024 | Jan 24, 2024 | A | 31,500 | $0.00 | $0 | 216,569 | No | Form 4 |
| Hull HansChief Business Officer | Jan 23, 2024 | Jan 24, 2024 | A · derivative | 63,000 | $17.44 | $1,098,720 | 63,000 | No | Form 4 |
| Lefebvre EricChief Medical Officer | Jan 23, 2024 | Jan 24, 2024 | A | 42,900 | $0.00 | $0 | 199,820 | No | Form 4 |
| Lefebvre EricChief Medical Officer | Jan 23, 2024 | Jan 24, 2024 | A · derivative | 85,800 | $17.44 | $1,496,352 | 85,800 | No | Form 4 |
| Ouimette MikeGeneral Counsel & Corp. Sec'y | Jan 17, 2024 | Jan 19, 2024 | S | 5,197 | $17.23 | Sale −$89,544 | 55,246 | Yes | Form 4 |
| Lefebvre EricChief Medical Officer | Jan 17, 2024 | Jan 19, 2024 | S | 10,295 | $17.23 | Sale −$177,383 | 156,920 | Yes | Form 4 |
| Coulie BernardPresident and CEO | Jan 17, 2024 | Jan 19, 2024 | S | 25,721 | $17.23 | Sale −$443,173 | 316,382 | Yes | Form 4 |
| Hull HansChief Business Officer | Jan 17, 2024 | Jan 19, 2024 | S | 9,786 | $17.23 | Sale −$168,613 | 185,069 | Yes | Form 4 |
| Cummings Keith LamontChief Financial Officer | Jan 17, 2024 | Jan 19, 2024 | S | 9,781 | $17.23 | Sale −$168,527 | 194,605 | Yes | Form 4 |