PTGXProtagonist Therapeutics, Inc
- Market cap
- $8.96B
- as of 2026-10-23
- Latest close
- $138.43
- as of 2026-10-23
- Sector
- Healthcare
- as of 2026-10-24
- Industry
- Biotechnology
- as of 2026-10-24
Cluster
No cluster in the last 90 days under the default rule (14d · ≥2 insiders · all roles).
Form 4 historysince 2023-10-19
Dashed line = amended filing (Form 4/A)
| Insider | Traded | Filed | Type | Shares | Price | Value | Owned after | 10b5-1 plan | Filing |
|---|---|---|---|---|---|---|---|---|---|
| Ali AsifChief Financial Officer | Sep 30 | Oct 2 | M | 9,229 | $38.98 | $359,746 | 68,232 | Yes | Form 4 |
| Ali AsifChief Financial Officer | Sep 30 | Oct 2 | M | 28,438 | $23.42 | $666,018 | 96,670 | Yes | Form 4 |
| Ali AsifChief Financial Officer | Sep 30 | Oct 2 | M | 15,650 | $19.19 | $300,324 | 112,320 | Yes | Form 4 |
| Ali AsifChief Financial Officer | Sep 30 | Oct 2 | M | 5,312 | $12.17 | $64,647 | 117,632 | Yes | Form 4 |
| Ali AsifChief Financial Officer | Sep 30 | Oct 2 | S | 12,595 | $141.77 | Sale −$1,785,593 | 105,037 | Yes | Form 4 |
| Ali AsifChief Financial Officer | Sep 30 | Oct 2 | S | 46,034 | $141.78 | Sale −$6,526,701 | 59,003 | Yes | Form 4 |
| Ali AsifChief Financial Officer | Sep 30 | Oct 2 | M · derivative | 9,229 | $38.98 | $359,746 | 29,291 | Yes | Form 4 |
| Ali AsifChief Financial Officer | Sep 30 | Oct 2 | M · derivative | 28,438 | $23.42 | $666,018 | 49,562 | Yes | Form 4 |
| Ali AsifChief Financial Officer | Sep 30 | Oct 2 | M · derivative | 15,650 | $19.19 | $300,324 | 51,150 | Yes | Form 4 |
| Ali AsifChief Financial Officer | Sep 30 | Oct 2 | M · derivative | 5,312 | $12.17 | $64,647 | 25,235 | Yes | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Sep 10 | Sep 10 | M | 7,278 | $21.58 | $157,059 | 530,246 | Yes | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Sep 10 | Sep 10 | S | 7,278 | $144.10 | Sale −$1,048,760 | 522,968 | Yes | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Sep 10 | Sep 10 | M · derivative | 7,278 | $21.58 | $157,059 | not reported | Yes | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Sep 9 | Sep 10 | M | 63,548 | $21.58 | $1,371,366 | 586,516 | Yes | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Sep 9 | Sep 10 | S | 63,548 | $146.18 | Sale −$9,289,447 | 522,968 | Yes | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Sep 9 | Sep 10 | M · derivative | 63,548 | $21.58 | $1,371,366 | 7,278 | Yes | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Sep 8 | Sep 10 | M | 54,174 | $21.58 | $1,169,075 | 577,142 | Yes | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Sep 8 | Sep 10 | S | 54,174 | $145.87 | Sale −$7,902,361 | 522,968 | Yes | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Sep 8 | Sep 10 | M · derivative | 54,174 | $21.58 | $1,169,075 | 70,826 | Yes | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Sep 3 | Sep 8 | G | 510 | $0.00 | $0 | 522,968 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Aug 11 | Aug 12 | M | 34,239 | $21.58 | $738,878 | 557,717 | Yes | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Aug 11 | Aug 12 | S | 34,239 | $148.52 | Sale −$5,085,176 | 523,478 | Yes | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Aug 11 | Aug 12 | M · derivative | 34,239 | $21.58 | $738,878 | 125,000 | Yes | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Aug 10 | Aug 12 | M | 65,761 | $21.58 | $1,419,122 | 589,239 | Yes | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Aug 10 | Aug 12 | S | 65,761 | $149.11 | Sale −$9,805,623 | 523,478 | Yes | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Aug 10 | Aug 12 | M · derivative | 65,761 | $21.58 | $1,419,122 | 159,239 | Yes | Form 4 |
| Waddill William D. | Jun 23 | Jun 25 | M | 9,000 | $16.54 | $148,860 | 16,825 | Yes | Form 4 |
| Waddill William D. | Jun 23 | Jun 25 | S | 9,000 | $117.94 | Sale −$1,061,460 | 7,825 | Yes | Form 4 |
| Waddill William D. | Jun 23 | Jun 25 | M · derivative | 9,000 | $16.54 | $148,860 | not reported | Yes | Form 4 |
| Waddill William D. | Jun 10 | Jun 11 | M | 3,000 | $11.80 | $35,400 | 10,825 | Yes | Form 4 |
| Waddill William D. | Jun 10 | Jun 11 | M | 6,000 | $16.54 | $99,240 | 16,825 | Yes | Form 4 |
| Waddill William D. | Jun 10 | Jun 11 | S | 9,000 | $107.68 | Sale −$969,120 | 7,825 | Yes | Form 4 |
| Waddill William D. | Jun 10 | Jun 11 | M · derivative | 3,000 | $11.80 | $35,400 | not reported | Yes | Form 4 |
| Waddill William D. | Jun 10 | Jun 11 | M · derivative | 6,000 | $16.54 | $99,240 | 9,000 | Yes | Form 4 |
| Waddill William D. | May 29 | Jun 1 | M | 9,000 | $11.80 | $106,200 | 16,825 | Yes | Form 4 |
| Waddill William D. | May 29 | Jun 1 | S | 9,000 | $99.64 | Sale −$896,760 | 7,825 | Yes | Form 4 |
| Waddill William D. | May 29 | Jun 1 | M · derivative | 9,000 | $11.80 | $106,200 | 3,000 | Yes | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | May 12 | May 144/A | M | 75,000 | $21.58 | $1,618,500 | 598,478 | Yes | Form 4/A |
| Patel Dinesh V Ph DPresident and CEO | May 12 | May 144/A | S | 75,000 | $100.12 | Sale −$7,509,000 | 523,478 | Yes | Form 4/A |
| Patel Dinesh V Ph DPresident and CEO | May 12 | May 144/A | M · derivative | 75,000 | $21.58 | $1,618,500 | 225,000 | Yes | Form 4/A |
| Giraudo Bryan | May 8 | May 11 | S | 6,000 | $100.00 | Sale −$600,000 | not reported | No | Form 4 |
| Giraudo Bryan | May 8 | May 11 | S | 5,130 | $100.00 | Sale −$513,000 | 12,695 | No | Form 4 |
| Giraudo Bryan | May 7 | May 11 | M | 24,000 | $6.45 | $154,800 | 31,825 | No | Form 4 |
| Giraudo Bryan | May 7 | May 11 | M | 12,000 | $6.98 | $83,760 | 43,825 | No | Form 4 |
| Giraudo Bryan | May 7 | May 11 | S | 36,000 | $100.14 | Sale −$3,605,040 | 27,825 | No | Form 4 |
| Giraudo Bryan | May 7 | May 11 | S | 12,000 | $100.07 | Sale −$1,200,840 | 6,000 | No | Form 4 |
| Giraudo Bryan | May 7 | May 11 | M · derivative | 24,000 | $6.45 | $154,800 | not reported | No | Form 4 |
| Giraudo Bryan | May 7 | May 11 | M · derivative | 12,000 | $6.98 | $83,760 | not reported | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Apr 23 | Apr 24 | G | 1,460 | $0.00 | $0 | 523,478 | No | Form 4 |
| Ali AsifChief Financial Officer | Apr 20 | Apr 21 | S | 1,750 | $105.47 | Sale −$184,573 | 59,003 | No | Form 4 |
| Ali AsifChief Financial Officer | Mar 26 | Mar 27 | M | 19,500 | $19.19 | $374,205 | 80,253 | No | Form 4 |
| Ali AsifChief Financial Officer | Mar 26 | Mar 27 | M | 5,265 | $12.17 | $64,075 | 85,518 | No | Form 4 |
| Ali AsifChief Financial Officer | Mar 26 | Mar 27 | S | 24,765 | $104.24 | Sale −$2,581,504 | 60,753 | No | Form 4 |
| Ali AsifChief Financial Officer | Mar 26 | Mar 27 | M · derivative | 19,500 | $19.19 | $374,205 | 31,300 | No | Form 4 |
| Ali AsifChief Financial Officer | Mar 26 | Mar 27 | M · derivative | 5,265 | $12.17 | $64,075 | 13,282 | No | Form 4 |
| Selick Harold E | Mar 26 | Mar 27 | M | 24,000 | $12.88 | $309,120 | 84,845 | No | Form 4 |
| Selick Harold E | Mar 26 | Mar 27 | S | 24,000 | $105.00 | Sale −$2,520,000 | 60,845 | No | Form 4 |
| Selick Harold E | Mar 26 | Mar 27 | M · derivative | 24,000 | $12.88 | $309,120 | not reported | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Mar 26 | Mar 27 | M | 15,000 | $8.04 | $120,600 | 99,115 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Mar 26 | Mar 27 | S | 15,000 | $104.79 | Sale −$1,571,850 | 84,115 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Mar 26 | Mar 27 | M · derivative | 15,000 | $8.04 | $120,600 | 50,971 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Mar 25 | Mar 25 | M | 54,641 | $8.58 | $468,820 | 579,579 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Mar 25 | Mar 25 | S | 54,641 | $101.00 | Sale −$5,518,741 | 524,938 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Mar 25 | Mar 25 | M · derivative | 54,641 | $8.58 | $468,820 | not reported | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Mar 24 | Mar 25 | M | 59 | $8.58 | $506 | 524,997 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Mar 24 | Mar 25 | S | 59 | $101.00 | Sale −$5,959 | 524,938 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Mar 24 | Mar 25 | M · derivative | 59 | $8.58 | $506 | 54,641 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Mar 23 | Mar 25 | G | 50,000 | $0.00 | $0 | 524,938 | No | Form 4 |
| Williams Lewis T | Feb 17 | Feb 18 | M | 18,000 | $10.84 | $195,120 | 25,825 | No | Form 4 |
| Williams Lewis T | Feb 17 | Feb 18 | S | 18,000 | $82.42 | Sale −$1,483,560 | 7,825 | No | Form 4 |
| Williams Lewis T | Feb 17 | Feb 18 | M · derivative | 18,000 | $10.84 | $195,120 | 6,000 | No | Form 4 |
| Waddill William D. | Feb 6 | Feb 6 | M | 20,000 | $8.31 | $166,200 | 27,825 | No | Form 4 |
| Waddill William D. | Feb 6 | Feb 6 | S | 20,000 | $83.68 | Sale −$1,673,600 | 7,825 | No | Form 4 |
| Waddill William D. | Feb 6 | Feb 6 | M · derivative | 20,000 | $8.31 | $166,200 | not reported | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jan 27 | Jan 27 | M | 5,000 | $8.04 | $40,200 | 89,115 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jan 27 | Jan 27 | S | 5,000 | $82.00 | Sale −$410,000 | 84,115 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jan 27 | Jan 27 | M · derivative | 5,000 | $8.04 | $40,200 | 65,971 | No | Form 4 |
| Ali AsifChief Financial Officer | Jan 27 | Jan 27 | M | 16,000 | $19.19 | $307,040 | 94,523 | No | Form 4 |
| Ali AsifChief Financial Officer | Jan 27 | Jan 27 | M | 12,000 | $12.17 | $146,040 | 106,523 | No | Form 4 |
| Ali AsifChief Financial Officer | Jan 27 | Jan 27 | S | 28,000 | $83.13 | Sale −$2,327,640 | 78,523 | No | Form 4 |
| Ali AsifChief Financial Officer | Jan 27 | Jan 27 | S | 18,203 | $83.14 | Sale −$1,513,397 | 60,320 | No | Form 4 |
| Ali AsifChief Financial Officer | Jan 27 | Jan 27 | M · derivative | 16,000 | $19.19 | $307,040 | 50,800 | No | Form 4 |
| Ali AsifChief Financial Officer | Jan 27 | Jan 27 | M · derivative | 12,000 | $12.17 | $146,040 | 18,547 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jan 27 | Jan 27 | M | 4,068 | $21.58 | $87,787 | 578,573 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jan 27 | Jan 27 | S | 4,068 | $83.19 | Sale −$338,417 | 574,505 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jan 27 | Jan 27 | M · derivative | 4,068 | $21.58 | $87,787 | 300,000 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jan 26 | Jan 27 | M | 5,000 | $8.04 | $40,200 | 89,115 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jan 26 | Jan 27 | S | 5,000 | $82.28 | Sale −$411,400 | 84,115 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jan 26 | Jan 27 | M · derivative | 5,000 | $8.04 | $40,200 | 70,971 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jan 26 | Jan 27 | M | 10,685 | $4.21 | $44,984 | 585,190 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jan 26 | Jan 27 | S | 10,685 | $84.00 | Sale −$897,540 | 574,505 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jan 26 | Jan 27 | M | 14,205 | $21.58 | $306,544 | 588,710 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jan 26 | Jan 27 | S | 14,205 | $84.05 | Sale −$1,193,930 | 574,505 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jan 26 | Jan 27 | M · derivative | 10,685 | $4.21 | $44,984 | not reported | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jan 26 | Jan 27 | M · derivative | 14,205 | $21.58 | $306,544 | 304,068 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jan 23 | Jan 27 | S | 13,151 | $82.42 | Sale −$1,083,905 | 84,115 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jan 23 | Jan 27 | G | 6,000 | $0.00 | $0 | 574,505 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jan 23 | Jan 27 | M | 19,315 | $4.21 | $81,316 | 593,820 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jan 23 | Jan 27 | S | 19,315 | $84.59 | Sale −$1,633,856 | 574,505 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jan 23 | Jan 27 | M · derivative | 19,315 | $4.21 | $81,316 | 10,685 | No | Form 4 |
| Ali AsifChief Financial Officer | Jan 20 | Jan 21 | S | 8,588 | $82.48 | Sale −$708,338 | 78,077 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jan 20 | Jan 21 | S | 34,438 | $82.48 | Sale −$2,840,446 | 580,505 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jan 20 | Jan 21 | S | 9,514 | $82.48 | Sale −$784,715 | 97,266 | No | Form 4 |
| Selick Harold E | Jan 9 | Jan 13 | M | 14,299 | $4.21 | $60,199 | 60,845 | No | Form 4 |
| Selick Harold E | Jan 9 | Jan 13 | M · derivative | 14,299 | $4.21 | $60,199 | not reported | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jan 2 | Jan 6 | A | 25,600 | $0.00 | $0 | 106,780 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jan 2 | Jan 6 | A · derivative | 32,000 | $87.18 | $2,789,760 | 32,000 | No | Form 4 |
| Ali AsifChief Financial Officer | Jan 2 | Jan 6 | A | 25,600 | $0.00 | $0 | 86,665 | No | Form 4 |
| Ali AsifChief Financial Officer | Jan 2 | Jan 6 | A · derivative | 32,000 | $87.18 | $2,789,760 | 32,000 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jan 2 | Jan 6 | A | 95,400 | $0.00 | $0 | 614,943 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jan 2 | Jan 6 | A · derivative | 120,200 | $87.18 | $10,479,036 | 120,200 | No | Form 4 |
| O'Dowd Sarah A | Jan 2 | Jan 6 | A | 2,695 | $0.00 | $0 | 7,825 | No | Form 4 |
| O'Dowd Sarah A | Jan 2 | Jan 6 | A · derivative | 3,762 | $87.18 | $327,971 | 3,762 | No | Form 4 |
| Williams Lewis T | Jan 2 | Jan 6 | A | 2,695 | $0.00 | $0 | 7,825 | No | Form 4 |
| Williams Lewis T | Jan 2 | Jan 6 | A · derivative | 3,762 | $87.18 | $327,971 | 3,762 | No | Form 4 |
| Giraudo Bryan | Jan 2 | Jan 6 | A | 2,695 | $0.00 | $0 | 17,825 | No | Form 4 |
| Giraudo Bryan | Jan 2 | Jan 6 | A · derivative | 3,762 | $87.18 | $327,971 | 3,762 | No | Form 4 |
| Waddill William D. | Jan 2 | Jan 6 | A | 2,695 | $0.00 | $0 | 7,825 | No | Form 4 |
| Waddill William D. | Jan 2 | Jan 6 | A · derivative | 3,762 | $87.18 | $327,971 | 3,762 | No | Form 4 |
| Selick Harold E | Jan 2 | Jan 6 | A | 2,695 | $0.00 | $0 | 46,546 | No | Form 4 |
| Selick Harold E | Jan 2 | Jan 6 | A · derivative | 3,762 | $87.18 | $327,971 | 3,762 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Nov 21, 2025 | Nov 24, 2025 | G | 440 | $0.00 | $0 | 519,543 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Nov 17, 2025 | Nov 19, 2025 | S | 2,712 | $84.77 | Sale −$229,896 | 81,180 | No | Form 4 |
| Waddill William D. | Oct 10, 2025 | Oct 14, 2025 | M | 12,000 | $6.98 | $83,760 | 17,130 | Yes | Form 4 |
| Waddill William D. | Oct 10, 2025 | Oct 14, 2025 | S | 4,000 | $69.25 | Sale −$277,000 | 13,130 | Yes | Form 4 |
| Waddill William D. | Oct 10, 2025 | Oct 14, 2025 | S | 8,000 | $87.81 | Sale −$702,480 | 5,130 | Yes | Form 4 |
| Waddill William D. | Oct 10, 2025 | Oct 14, 2025 | M · derivative | 12,000 | $6.98 | $83,760 | not reported | Yes | Form 4 |
| Waddill William D. | Sep 22, 2025 | Sep 24, 2025 | S | 4,000 | $64.25 | Sale −$257,000 | 5,130 | Yes | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Sep 16, 2025 | Sep 18, 2025 | G | 620 | $0.00 | $0 | 519,983 | No | Form 4 |
| Waddill William D. | Aug 27, 2025 | Aug 29, 2025 | S | 4,000 | $59.25 | Sale −$237,000 | 9,130 | Yes | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jul 25, 2025 | Jul 28, 2025 | S | 10,415 | $54.78 | Sale −$570,534 | 520,603 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jul 23, 2025 | Jul 23, 2025 | S | 17,520 | $54.79 | Sale −$959,921 | 531,018 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jul 22, 2025 | Jul 23, 2025 | S | 22,065 | $55.05 | Sale −$1,214,678 | 548,538 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jul 21, 2025 | Jul 23, 2025 | A | 25,000 | $0.00 | $0 | 583,462 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jul 21, 2025 | Jul 23, 2025 | S | 12,859 | $54.86 | Sale −$705,445 | 570,603 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jul 16, 2025 | Jul 18, 2025 | G | 5,000 | $0.00 | $0 | 558,462 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jun 16, 2025 | Jun 17, 2025 | G | 685 | $0.00 | $0 | 562,905 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jun 13, 2025 | Jun 17, 2025 | G | 670 | $0.00 | $0 | 563,590 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jun 10, 2025 | Jun 11, 2025 | M | 10,000 | $8.04 | $80,400 | 93,892 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jun 10, 2025 | Jun 11, 2025 | S | 10,000 | $57.03 | Sale −$570,300 | 83,892 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jun 10, 2025 | Jun 11, 2025 | M · derivative | 10,000 | $8.04 | $80,400 | 75,971 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jun 9, 2025 | Jun 11, 2025 | M | 10,000 | $8.04 | $80,400 | 93,892 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jun 9, 2025 | Jun 11, 2025 | S | 10,000 | $55.51 | Sale −$555,100 | 83,892 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jun 9, 2025 | Jun 11, 2025 | M · derivative | 10,000 | $8.04 | $80,400 | 85,971 | No | Form 4 |
| Selick Harold E | Apr 28, 2025 | Apr 30, 2025 | M | 10,725 | $1.16 | $12,441 | 43,851 | No | Form 4 |
| Selick Harold E | Apr 28, 2025 | Apr 30, 2025 | M · derivative | 10,725 | $1.16 | $12,441 | not reported | No | Form 4 |
| Ali AsifChief Financial Officer | Apr 22, 2025 | Apr 23, 2025 | S | 1,756 | $46.00 | Sale −$80,776 | 61,065 | No | Form 4 |
| Waddill William D. | Mar 17, 2025 | Mar 19, 2025 | S | 4,000 | $54.25 | Sale −$217,000 | 13,130 | Yes | Form 4 |
| Molina Arturo MdChief Medical Officer | Mar 13, 2025 | Mar 14, 2025 | M | 28,437 | $23.42 | $665,995 | 112,329 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Mar 13, 2025 | Mar 14, 2025 | M | 2,077 | $38.98 | $80,961 | 114,406 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Mar 13, 2025 | Mar 14, 2025 | S | 30,514 | $55.74 | Sale −$1,700,850 | 83,892 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Mar 13, 2025 | Mar 14, 2025 | M · derivative | 28,437 | $23.42 | $665,995 | 69,063 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Mar 13, 2025 | Mar 14, 2025 | M · derivative | 2,077 | $38.98 | $80,961 | 47,785 | No | Form 4 |
| Ali AsifChief Financial Officer | Mar 12, 2025 | Mar 14, 2025 | M | 15,203 | $12.17 | $185,021 | 78,024 | No | Form 4 |
| Ali AsifChief Financial Officer | Mar 12, 2025 | Mar 14, 2025 | M | 9,700 | $19.19 | $186,143 | 87,724 | No | Form 4 |
| Ali AsifChief Financial Officer | Mar 12, 2025 | Mar 14, 2025 | S | 24,903 | $58.73 | Sale −$1,462,553 | 62,821 | No | Form 4 |
| Ali AsifChief Financial Officer | Mar 12, 2025 | Mar 14, 2025 | M · derivative | 15,203 | $12.17 | $185,021 | 30,547 | No | Form 4 |
| Ali AsifChief Financial Officer | Mar 12, 2025 | Mar 14, 2025 | M · derivative | 9,700 | $19.19 | $186,143 | 66,800 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Mar 5, 2025 | Mar 5, 2025 | M | 24,000 | $4.21 | $101,040 | 564,260 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Mar 5, 2025 | Mar 5, 2025 | M · derivative | 24,000 | $4.21 | $101,040 | 30,000 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Feb 19, 2025 | Feb 20, 2025 | S | 5,359 | $38.18 | Sale −$204,607 | 540,260 | No | Form 4 |
| Ali AsifChief Financial Officer | Jan 16, 2025 | Jan 17, 2025 | S | 1,317 | $0.00 | Sale −$0 | 65,422 | No | Form 4 |
| Ali AsifChief Financial Officer | Jan 16, 2025 | Jan 17, 2025 | S | 2,601 | $0.00 | Sale −$0 | 62,821 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jan 16, 2025 | Jan 17, 2025 | S | 388 | $0.00 | Sale −$0 | 87,144 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jan 16, 2025 | Jan 17, 2025 | S | 3,252 | $0.00 | Sale −$0 | 83,892 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jan 15, 2025 | Jan 17, 2025 | F | 12,636 | $0.00 | $0 | 545,619 | No | Form 4 |
| Ali AsifChief Financial Officer | Jan 2, 2025 | Jan 6, 2025 | A | 31,779 | $0.00 | $0 | 66,739 | No | Form 4 |
| Ali AsifChief Financial Officer | Jan 2, 2025 | Jan 6, 2025 | A · derivative | 38,520 | $38.98 | $1,501,510 | 38,520 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jan 2, 2025 | Jan 6, 2025 | A | 41,088 | $0.00 | $0 | 87,532 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jan 2, 2025 | Jan 6, 2025 | A · derivative | 49,862 | $38.98 | $1,943,621 | 49,862 | No | Form 4 |
| Giraudo Bryan | Jan 2, 2025 | Jan 6, 2025 | A | 5,130 | $0.00 | $0 | 15,130 | No | Form 4 |
| Giraudo Bryan | Jan 2, 2025 | Jan 6, 2025 | A · derivative | 6,584 | $38.98 | $256,644 | 6,584 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jan 2, 2025 | Jan 6, 2025 | A | 149,800 | $0.00 | $0 | 558,255 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jan 2, 2025 | Jan 6, 2025 | A · derivative | 181,472 | $38.98 | $7,073,779 | 181,472 | No | Form 4 |
| Selick Harold E | Jan 2, 2025 | Jan 6, 2025 | A | 5,130 | $0.00 | $0 | 33,126 | No | Form 4 |
| Selick Harold E | Jan 2, 2025 | Jan 6, 2025 | A · derivative | 6,584 | $38.98 | $256,644 | 6,584 | No | Form 4 |
| Williams Lewis T | Jan 2, 2025 | Jan 6, 2025 | A | 5,130 | $0.00 | $0 | 5,130 | No | Form 4 |
| Williams Lewis T | Jan 2, 2025 | Jan 6, 2025 | A · derivative | 6,584 | $38.98 | $256,644 | 6,584 | No | Form 4 |
| O'Dowd Sarah A | Jan 2, 2025 | Jan 6, 2025 | A | 5,130 | $0.00 | $0 | 5,130 | No | Form 4 |
| O'Dowd Sarah A | Jan 2, 2025 | Jan 6, 2025 | A · derivative | 6,584 | $38.98 | $256,644 | 6,584 | No | Form 4 |
| Waddill William D. | Jan 2, 2025 | Jan 6, 2025 | A | 5,130 | $0.00 | $0 | 17,130 | No | Form 4 |
| Waddill William D. | Jan 2, 2025 | Jan 6, 2025 | A · derivative | 6,584 | $38.98 | $256,644 | 6,584 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Nov 27, 2024 | Nov 27, 2024 | M | 10,000 | $8.04 | $80,400 | 56,444 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Nov 27, 2024 | Nov 27, 2024 | S | 10,000 | $44.50 | Sale −$445,000 | 46,444 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Nov 27, 2024 | Nov 27, 2024 | M | 16,000 | $8.04 | $128,640 | 62,444 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Nov 27, 2024 | Nov 27, 2024 | S | 16,000 | $44.83 | Sale −$717,280 | 46,444 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Nov 27, 2024 | Nov 27, 2024 | M · derivative | 10,000 | $8.04 | $80,400 | 111,971 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Nov 27, 2024 | Nov 27, 2024 | M · derivative | 16,000 | $8.04 | $128,640 | 95,971 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Nov 26, 2024 | Nov 27, 2024 | S | 21,480 | $46.25 | Sale −$993,450 | 408,455 | No | Form 4 |
| Gupta SuneelChief Development Officer | Nov 26, 2024 | Nov 27, 2024 | M | 30,000 | $12.17 | $365,100 | 286,174 | No | Form 4 |
| Gupta SuneelChief Development Officer | Nov 26, 2024 | Nov 27, 2024 | S | 19,191 | $45.50 | Sale −$873,191 | 266,983 | No | Form 4 |
| Gupta SuneelChief Development Officer | Nov 26, 2024 | Nov 27, 2024 | M | 450 | $12.17 | $5,477 | 267,433 | No | Form 4 |
| Gupta SuneelChief Development Officer | Nov 26, 2024 | Nov 27, 2024 | M · derivative | 30,000 | $12.17 | $365,100 | 93,750 | No | Form 4 |
| Gupta SuneelChief Development Officer | Nov 26, 2024 | Nov 27, 2024 | M · derivative | 450 | $12.17 | $5,477 | 93,300 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Nov 26, 2024 | Nov 27, 2024 | M | 5,529 | $8.04 | $44,453 | 51,973 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Nov 26, 2024 | Nov 27, 2024 | S | 5,529 | $45.60 | Sale −$252,122 | 46,444 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Nov 26, 2024 | Nov 27, 2024 | M · derivative | 5,529 | $8.04 | $44,453 | 121,971 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Nov 25, 2024 | Nov 27, 2024 | S | 78,520 | $46.96 | Sale −$3,687,299 | 435,208 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Nov 25, 2024 | Nov 27, 2024 | G | 7,000 | $0.00 | $0 | 428,208 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Nov 25, 2024 | Nov 27, 2024 | M | 1,727 | $21.58 | $37,269 | 429,935 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Nov 25, 2024 | Nov 27, 2024 | M · derivative | 1,727 | $21.58 | $37,269 | 318,273 | No | Form 4 |
| Gupta SuneelChief Development Officer | Nov 25, 2024 | Nov 27, 2024 | M | 45,000 | $7.38 | $332,100 | 229,611 | No | Form 4 |
| Gupta SuneelChief Development Officer | Nov 25, 2024 | Nov 27, 2024 | M | 45,000 | $8.02 | $360,900 | 274,611 | No | Form 4 |
| Gupta SuneelChief Development Officer | Nov 25, 2024 | Nov 27, 2024 | M | 85,000 | $7.80 | $663,000 | 359,611 | No | Form 4 |
| Gupta SuneelChief Development Officer | Nov 25, 2024 | Nov 27, 2024 | S | 103,437 | $46.04 | Sale −$4,762,239 | 256,174 | No | Form 4 |
| Gupta SuneelChief Development Officer | Nov 25, 2024 | Nov 27, 2024 | M · derivative | 45,000 | $7.38 | $332,100 | not reported | No | Form 4 |
| Gupta SuneelChief Development Officer | Nov 25, 2024 | Nov 27, 2024 | M · derivative | 45,000 | $8.02 | $360,900 | not reported | No | Form 4 |
| Gupta SuneelChief Development Officer | Nov 25, 2024 | Nov 27, 2024 | M · derivative | 85,000 | $7.80 | $663,000 | not reported | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Nov 19, 2024 | Nov 21, 2024 | G | 1,000 | $0.00 | $0 | 513,415 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Nov 15, 2024 | Nov 19, 2024 | S | 1,906 | $40.98 | Sale −$78,108 | 46,444 | No | Form 4 |
| Ali AsifChief Financial Officer | Sep 11, 2024 | Sep 13, 2024 | S | 2,203 | $44.59 | Sale −$98,232 | 34,960 | No | Form 4 |
| Ali AsifChief Financial Officer | Sep 11, 2024 | Sep 13, 2024 | M | 6,000 | $19.19 | $115,140 | 40,960 | No | Form 4 |
| Ali AsifChief Financial Officer | Sep 11, 2024 | Sep 13, 2024 | M | 6,000 | $12.17 | $73,020 | 46,960 | No | Form 4 |
| Ali AsifChief Financial Officer | Sep 11, 2024 | Sep 13, 2024 | S | 12,000 | $44.47 | Sale −$533,640 | 34,960 | No | Form 4 |
| Ali AsifChief Financial Officer | Sep 11, 2024 | Sep 13, 2024 | M · derivative | 6,000 | $19.19 | $115,140 | 76,500 | No | Form 4 |
| Ali AsifChief Financial Officer | Sep 11, 2024 | Sep 13, 2024 | M · derivative | 6,000 | $12.17 | $73,020 | 45,750 | No | Form 4 |
| Waddill William D. | Sep 10, 2024 | Sep 12, 2024 | M | 8,000 | $12.88 | $103,040 | 20,000 | Yes | Form 4 |
| Waddill William D. | Sep 10, 2024 | Sep 12, 2024 | S | 8,000 | $45.00 | Sale −$360,000 | 12,000 | Yes | Form 4 |
| Waddill William D. | Sep 10, 2024 | Sep 12, 2024 | M · derivative | 8,000 | $12.88 | $103,040 | not reported | Yes | Form 4 |
| Waddill William D. | Jul 24, 2024 | Jul 26, 2024 | M | 8,000 | $12.88 | $103,040 | 20,000 | Yes | Form 4 |
| Waddill William D. | Jul 24, 2024 | Jul 26, 2024 | S | 8,000 | $40.00 | Sale −$320,000 | 12,000 | Yes | Form 4 |
| Waddill William D. | Jul 24, 2024 | Jul 26, 2024 | M · derivative | 8,000 | $12.88 | $103,040 | 8,000 | Yes | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jun 13, 2024 | Jun 17, 2024 | G | 1,000 | $0.00 | $0 | 514,415 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jun 7, 2024 | Jun 11, 2024 | S | 35,000 | $35.19 | Sale −$1,231,650 | 515,415 | Yes | Form 4 |
| Waddill William D. | Jun 7, 2024 | Jun 11, 2024 | M | 8,000 | $12.88 | $103,040 | 20,000 | Yes | Form 4 |
| Waddill William D. | Jun 7, 2024 | Jun 11, 2024 | S | 8,000 | $35.00 | Sale −$280,000 | 12,000 | Yes | Form 4 |
| Waddill William D. | Jun 7, 2024 | Jun 11, 2024 | M · derivative | 8,000 | $12.88 | $103,040 | 16,000 | Yes | Form 4 |
| Ali AsifChief Financial Officer | Apr 18, 2024 | Apr 19, 2024 | S | 1,234 | $25.11 | Sale −$30,986 | 37,163 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Apr 1, 2024 | Apr 2, 2024 | S | 25,000 | $28.31 | Sale −$707,750 | 549,590 | Yes | Form 4 |
| Selick Harold E | Mar 7, 2024 | Mar 11, 2024 | M | 6,490 | $1.89 | $12,266 | 27,996 | No | Form 4 |
| Selick Harold E | Mar 7, 2024 | Mar 11, 2024 | M · derivative | 6,490 | $1.89 | $12,266 | not reported | No | Form 4 |
| Ali AsifChief Financial Officer | Mar 1, 2024 | Mar 1, 2024 | M | 12,000 | $12.17 | $146,040 | 52,645 | No | Form 4 |
| Ali AsifChief Financial Officer | Mar 1, 2024 | Mar 1, 2024 | S | 12,000 | $32.22 | Sale −$386,640 | 40,645 | No | Form 4 |
| Ali AsifChief Financial Officer | Mar 1, 2024 | Mar 1, 2024 | S | 2,248 | $32.33 | Sale −$72,678 | 38,397 | No | Form 4 |
| Ali AsifChief Financial Officer | Mar 1, 2024 | Mar 1, 2024 | M · derivative | 12,000 | $12.17 | $146,040 | 51,750 | No | Form 4 |
| Waddill William D. | Mar 1, 2024 | Mar 1, 2024 | M | 12,975 | $6.09 | $79,018 | 24,975 | Yes | Form 4 |
| Waddill William D. | Mar 1, 2024 | Mar 1, 2024 | S | 12,975 | $31.34 | Sale −$406,637 | 12,000 | Yes | Form 4 |
| Waddill William D. | Mar 1, 2024 | Mar 1, 2024 | M · derivative | 12,975 | $6.09 | $79,018 | not reported | Yes | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Mar 1, 2024 | Mar 1, 2024 | S | 30,000 | $31.62 | Sale −$948,600 | 574,590 | Yes | Form 4 |
| Ali AsifChief Financial Officer | Feb 29, 2024 | Mar 1, 2024 | S | 7,850 | $30.61 | Sale −$240,289 | 42,734 | No | Form 4 |
| Ali AsifChief Financial Officer | Feb 29, 2024 | Mar 1, 2024 | S | 2,089 | $31.00 | Sale −$64,759 | 40,645 | No | Form 4 |
| Gupta SuneelChief Development Officer | Feb 26, 2024 | Feb 28, 2024 | F | 4,282 | $29.53 | $126,447 | 183,285 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Feb 26, 2024 | Feb 28, 2024 | F | 10,915 | $29.53 | $322,320 | 604,590 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Feb 15, 2024 | Feb 20, 2024 | F | 3,717 | $28.23 | $104,931 | 615,505 | No | Form 4 |
| Ali AsifChief Financial Officer | Jan 16, 2024 | Jan 18, 2024 | F | 1,452 | $24.63 | $35,763 | 50,584 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jan 16, 2024 | Jan 18, 2024 | F | 427 | $24.63 | $10,517 | 48,350 | No | Form 4 |
| Gupta SuneelChief Development Officer | Jan 9, 2024 | Jan 11, 2024 | M | 5,000 | $7.38 | $36,900 | 192,567 | Yes | Form 4 |
| Gupta SuneelChief Development Officer | Jan 9, 2024 | Jan 11, 2024 | S | 5,000 | $25.00 | Sale −$125,000 | 187,567 | Yes | Form 4 |
| Gupta SuneelChief Development Officer | Jan 9, 2024 | Jan 11, 2024 | M · derivative | 5,000 | $7.38 | $36,900 | 45,000 | Yes | Form 4 |
| Ali AsifChief Financial Officer | Jan 2, 2024 | Jan 4, 2024 | A | 21,000 | $0.00 | $0 | 52,036 | No | Form 4 |
| Ali AsifChief Financial Officer | Jan 2, 2024 | Jan 4, 2024 | A · derivative | 78,000 | $23.42 | $1,826,760 | 78,000 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jan 2, 2024 | Jan 4, 2024 | A | 26,250 | $0.00 | $0 | 48,777 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Jan 2, 2024 | Jan 4, 2024 | A · derivative | 97,500 | $23.42 | $2,283,450 | 97,500 | No | Form 4 |
| Giraudo Bryan | Jan 2, 2024 | Jan 4, 2024 | A · derivative | 25,700 | $23.42 | $601,894 | 25,700 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jan 2, 2024 | Jan 4, 2024 | A | 84,875 | $0.00 | $0 | 619,222 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Jan 2, 2024 | Jan 4, 2024 | A · derivative | 315,250 | $23.42 | $7,383,155 | 315,250 | No | Form 4 |
| Selick Harold E | Jan 2, 2024 | Jan 4, 2024 | A · derivative | 25,700 | $23.42 | $601,894 | 25,700 | No | Form 4 |
| Williams Lewis T | Jan 2, 2024 | Jan 4, 2024 | A · derivative | 25,700 | $23.42 | $601,894 | 25,700 | No | Form 4 |
| Gupta SuneelChief Development Officer | Jan 2, 2024 | Jan 4, 2024 | A | 19,250 | $0.00 | $0 | 187,567 | No | Form 4 |
| Gupta SuneelChief Development Officer | Jan 2, 2024 | Jan 4, 2024 | A · derivative | 71,500 | $23.42 | $1,674,530 | 71,500 | No | Form 4 |
| O'Dowd Sarah A | Jan 2, 2024 | Jan 4, 2024 | A · derivative | 25,700 | $23.42 | $601,894 | 25,700 | No | Form 4 |
| Waddill William D. | Jan 2, 2024 | Jan 4, 2024 | A · derivative | 25,700 | $23.42 | $601,894 | 25,700 | No | Form 4 |
| Molina Arturo MdChief Medical Officer | Nov 15, 2023 | Jan 4, 2024 | S | 1,848 | $16.24 | Sale −$30,012 | 22,527 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Dec 13, 2023 | Dec 15, 2023 | S | 75,000 | $20.08 | Sale −$1,506,000 | 534,347 | Yes | Form 4 |
| Swisher Daniel N JR | Oct 26, 2023 | Oct 30, 2023 | A · derivative | 45,000 | $14.21 | $639,450 | 45,000 | No | Form 4 |
| Gupta SuneelChief Development Officer | Oct 19, 2023 | Oct 23, 2023 | M | 20,000 | $7.38 | $147,600 | 168,317 | No | Form 4 |
| Gupta SuneelChief Development Officer | Oct 19, 2023 | Oct 23, 2023 | M · derivative | 20,000 | $7.38 | $147,600 | 50,000 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Oct 18, 2023 | Oct 19, 2023 | M | 6,000 | $4.21 | $25,260 | 609,347 | No | Form 4 |
| Patel Dinesh V Ph DPresident and CEO | Oct 18, 2023 | Oct 19, 2023 | M · derivative | 6,000 | $4.21 | $25,260 | 54,000 | No | Form 4 |