SRRKScholar Rock Holding Corp
- Market cap
- $5.05B
- as of 2026-10-23
- Latest close
- $41.49
- as of 2026-10-23
- Sector
- Healthcare
- as of 2026-10-24
- Industry
- Biotechnology
- as of 2026-10-24
Cluster
No cluster in the last 90 days under the default rule (14d · ≥2 insiders · all roles).
Form 4 historysince 2023-10-16
| Insider | Traded | Filed | Type | Shares | Price | Value | Owned after | 10b5-1 plan | Filing |
|---|---|---|---|---|---|---|---|---|---|
| Woods KeithChief Operating Officer | Sep 24 | Sep 25 | G | 48,034 | $0.00 | $0 | 572,021 | No | Form 4 |
| Hallal DavidChief Executive Officer | Sep 21 | Sep 23 | G | 36,652 | $0.00 | $0 | 1,602,382 | No | Form 4 |
| Peng Katie | Jul 1 | Jul 6 | S | 2,988 | $53.56 | Sale −$160,037 | 36,759 | Yes | Form 4 |
| Peng Katie | Jul 1 | Jul 6 | S | 2,437 | $54.25 | Sale −$132,207 | 34,322 | Yes | Form 4 |
| Peng Katie | Jul 1 | Jul 6 | S | 21 | $54.96 | Sale −$1,154 | 34,301 | Yes | Form 4 |
| Reed Joshua | Jul 1 | Jul 6 | S | 2,105 | $53.50 | Sale −$112,618 | 20,466 | Yes | Form 4 |
| Reed Joshua | Jul 1 | Jul 6 | S | 948 | $54.28 | Sale −$51,457 | 19,518 | Yes | Form 4 |
| Burow Kristina | Jul 1 | Jul 6 | S | 2,105 | $53.49 | Sale −$112,596 | 115,605 | Yes | Form 4 |
| Burow Kristina | Jul 1 | Jul 6 | S | 948 | $54.28 | Sale −$51,457 | 114,657 | Yes | Form 4 |
| Gilman Michael | Jul 1 | Jul 6 | S | 1,346 | $53.54 | Sale −$72,065 | 60,709 | Yes | Form 4 |
| Gilman Michael | Jul 1 | Jul 6 | S | 1,155 | $54.23 | Sale −$62,636 | 59,554 | Yes | Form 4 |
| Gilman Michael | Jul 1 | Jul 6 | S | 43 | $54.81 | Sale −$2,357 | 59,511 | Yes | Form 4 |
| Flier Jeffrey S. | Jul 1 | Jul 6 | S | 1,568 | $53.53 | Sale −$83,935 | 29,341 | Yes | Form 4 |
| Flier Jeffrey S. | Jul 1 | Jul 6 | S | 1,470 | $54.24 | Sale −$79,733 | 27,871 | Yes | Form 4 |
| Flier Jeffrey S. | Jul 1 | Jul 6 | S | 15 | $54.88 | Sale −$823 | 27,856 | Yes | Form 4 |
| Akkaraju Srinivas | Jun 4 | Jun 8 | A | 6,839 | $0.00 | $0 | 27,971 | No | Form 4 |
| Akkaraju Srinivas | Jun 4 | Jun 8 | A · derivative | 4,310 | $45.33 | $195,372 | 4,310 | No | Form 4 |
| Peng Katie | Jun 4 | Jun 8 | A | 6,839 | $0.00 | $0 | 39,747 | No | Form 4 |
| Peng Katie | Jun 4 | Jun 8 | A · derivative | 4,310 | $45.33 | $195,372 | 4,310 | No | Form 4 |
| Gilman Michael | Jun 4 | Jun 8 | A | 6,839 | $0.00 | $0 | 62,055 | No | Form 4 |
| Gilman Michael | Jun 4 | Jun 8 | A · derivative | 4,310 | $45.33 | $195,372 | 4,310 | No | Form 4 |
| Burow Kristina | Jun 4 | Jun 8 | A | 6,839 | $0.00 | $0 | 117,710 | No | Form 4 |
| Burow Kristina | Jun 4 | Jun 8 | A · derivative | 4,310 | $45.33 | $195,372 | 4,310 | No | Form 4 |
| Brudnick Richard | Jun 4 | Jun 8 | A | 6,839 | $0.00 | $0 | 21,896 | No | Form 4 |
| Brudnick Richard | Jun 4 | Jun 8 | A · derivative | 4,310 | $45.33 | $195,372 | 4,310 | No | Form 4 |
| Reed Joshua | Jun 4 | Jun 8 | A | 6,839 | $0.00 | $0 | 22,571 | No | Form 4 |
| Reed Joshua | Jun 4 | Jun 8 | A · derivative | 4,310 | $45.33 | $195,372 | 4,310 | No | Form 4 |
| Flier Jeffrey S. | Jun 4 | Jun 8 | A | 6,839 | $0.00 | $0 | 30,909 | No | Form 4 |
| Flier Jeffrey S. | Jun 4 | Jun 8 | A · derivative | 4,310 | $45.33 | $195,372 | 4,310 | No | Form 4 |
| Burow Kristina | Apr 23 | Apr 24 | M | 7,800 | $26.78 | $208,884 | 28,871 | No | Form 4 |
| Burow Kristina | Apr 23 | Apr 24 | M | 28,000 | $4.75 | $133,000 | 56,871 | No | Form 4 |
| Burow Kristina | Apr 23 | Apr 24 | M | 36,000 | $9.11 | $327,960 | 92,871 | No | Form 4 |
| Burow Kristina | Apr 23 | Apr 24 | M | 18,000 | $8.36 | $150,480 | 110,871 | No | Form 4 |
| Burow Kristina | Apr 23 | Apr 24 | M · derivative | 7,800 | $26.78 | $208,884 | not reported | No | Form 4 |
| Burow Kristina | Apr 23 | Apr 24 | M · derivative | 28,000 | $4.75 | $133,000 | not reported | No | Form 4 |
| Burow Kristina | Apr 23 | Apr 24 | M · derivative | 36,000 | $9.11 | $327,960 | not reported | No | Form 4 |
| Burow Kristina | Apr 23 | Apr 24 | M · derivative | 18,000 | $8.36 | $150,480 | not reported | No | Form 4 |
| Hallal DavidChief Executive Officer | Apr 16 | Apr 20 | S | 30,615 | $49.57 | Sale −$1,517,586 | 1,639,034 | No | Form 4 |
| Sinha VikasChief Financial Officer | Apr 16 | Apr 20 | S | 10,410 | $49.57 | Sale −$516,024 | 619,856 | No | Form 4 |
| Vaishnaw AkshayPresident of R&D | Apr 16 | Apr 20 | S | 12,246 | $49.57 | Sale −$607,034 | 630,542 | No | Form 4 |
| Woods KeithChief Operating Officer | Apr 16 | Apr 20 | S | 10,220 | $49.57 | Sale −$506,605 | 620,055 | No | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Feb 23 | Feb 25 | S | 7,427 | $46.94 | Sale −$348,623 | 99,502 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Feb 23 | Feb 25 | S | 857 | $47.86 | Sale −$41,016 | 98,645 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Feb 23 | Feb 25 | S | 200 | $48.48 | Sale −$9,696 | 98,445 | Yes | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Feb 17 | Feb 19 | S | 4,157 | $46.53 | Sale −$193,425 | 126,012 | No | Form 4 |
| Ho JunlinGENERAL COUNSEL | Feb 17 | Feb 19 | S | 9,580 | $46.53 | Sale −$445,757 | 241,545 | No | Form 4 |
| Parlavecchio CarynCHRO | Feb 17 | Feb 19 | S | 9,035 | $46.53 | Sale −$420,399 | 169,087 | No | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Feb 17 | Feb 19 | S | 7,989 | $46.53 | Sale −$371,728 | 106,929 | No | Form 4 |
| Woods KeithChief Operating Officer | Feb 9 | Feb 11 | A | 47,021 | $0.00 | $0 | 630,275 | No | Form 4 |
| Hallal DavidChief Executive Officer | Feb 9 | Feb 11 | A | 128,004 | $0.00 | $0 | 1,669,649 | No | Form 4 |
| Ho JunlinGeneral Counsel | Feb 9 | Feb 11 | A | 36,572 | $0.00 | $0 | 251,125 | No | Form 4 |
| Marantz Jing L.Chief Medical Officer | Feb 9 | Feb 11 | A | 34,482 | $0.00 | $0 | 130,169 | No | Form 4 |
| Parlavecchio CarynChief Human Resources Officer | Feb 9 | Feb 11 | A | 29,258 | $0.00 | $0 | 178,122 | No | Form 4 |
| Qatanani MoChief Scientific Officer | Feb 9 | Feb 11 | A | 29,258 | $0.00 | $0 | 114,918 | No | Form 4 |
| Sinha VikasChief Financial Officer | Feb 9 | Feb 11 | A | 47,021 | $0.00 | $0 | 630,266 | No | Form 4 |
| Vaishnaw AkshayPresident of R&D | Feb 9 | Feb 11 | A | 47,021 | $0.00 | $0 | 642,788 | No | Form 4 |
| Siren, L.L.C. | Dec 11, 2025 | Feb 6 | X | 1,575,008 | $7.35 | $11,576,309 | 10,825,013 | No | Form 4 |
| Siren, L.L.C. | Dec 11, 2025 | Feb 6 | X · derivative | 1,575,008 | $7.35 | $11,576,309 | not reported | No | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Jan 22 | Jan 23 | S | 2,119 | $45.87 | Sale −$97,199 | 98,439 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Jan 22 | Jan 23 | S | 12,779 | $46.85 | Sale −$598,696 | 85,660 | Yes | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Jan 16 | Jan 21 | S | 5,798 | $44.48 | Sale −$257,895 | 95,687 | No | Form 4 |
| Ho JunlinGENERAL COUNSEL | Jan 16 | Jan 21 | S | 8,016 | $44.48 | Sale −$356,552 | 214,553 | No | Form 4 |
| Parlavecchio CarynCHRO | Jan 16 | Jan 21 | S | 6,600 | $44.48 | Sale −$293,568 | 148,864 | No | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Jan 16 | Jan 21 | S | 8,406 | $44.48 | Sale −$373,899 | 100,558 | No | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Jan 14 | Jan 16 | M | 1,407 | $18.08 | $25,439 | 110,371 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Jan 14 | Jan 16 | M | 321 | $7.62 | $2,446 | 110,692 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Jan 14 | Jan 16 | M | 2,813 | $10.00 | $28,130 | 113,505 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Jan 14 | Jan 16 | M | 5,893 | $15.75 | $92,815 | 119,398 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Jan 14 | Jan 16 | M | 2,678 | $35.15 | $94,132 | 122,076 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Jan 14 | Jan 16 | S | 13,112 | $45.20 | Sale −$592,662 | 108,964 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Jan 14 | Jan 16 | M · derivative | 1,407 | $18.08 | $25,439 | not reported | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Jan 14 | Jan 16 | M · derivative | 321 | $7.62 | $2,446 | 961 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Jan 14 | Jan 16 | M · derivative | 2,813 | $10.00 | $28,130 | 11,250 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Jan 14 | Jan 16 | M · derivative | 5,893 | $15.75 | $92,815 | 47,143 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Jan 14 | Jan 16 | M · derivative | 2,678 | $35.15 | $94,132 | 32,142 | Yes | Form 4 |
| Hallal DavidChief Executive Officer | Jan 13 | Jan 15 | S | 57,450 | $42.70 | Sale −$2,453,115 | 1,541,645 | No | Form 4 |
| Vaishnaw AkshayPresident of R&D | Jan 13 | Jan 15 | S | 20,438 | $42.70 | Sale −$872,703 | 595,767 | No | Form 4 |
| Woods KeithChief Operating Officer | Jan 13 | Jan 15 | S | 16,746 | $42.70 | Sale −$715,054 | 583,254 | No | Form 4 |
| Sinha VikasChief Financial Officer | Jan 13 | Jan 15 | S | 16,755 | $42.70 | Sale −$715,439 | 583,245 | No | Form 4 |
| Peng Katie | Dec 16, 2025 | Dec 18, 2025 | S | 726 | $43.88 | Sale −$31,857 | 33,188 | Yes | Form 4 |
| Peng Katie | Dec 16, 2025 | Dec 18, 2025 | S | 280 | $44.63 | Sale −$12,496 | 32,908 | Yes | Form 4 |
| Akkaraju Srinivas | Dec 12, 2025 | Dec 16, 2025 | X | 1,064,804 | $7.35 | $7,826,309 | 6,367,614 | No | Form 4 |
| Akkaraju Srinivas | Dec 12, 2025 | Dec 16, 2025 | X · derivative | 1,064,804 | $7.35 | $7,826,309 | not reported | No | Form 4 |
| Akkaraju Srinivas | Oct 7, 2025 | Dec 16, 2025 | P | 12,796 | $39.31 | Purchase +$503,011 | 513,235 | No | Form 4 |
| Akkaraju Srinivas | Oct 7, 2025 | Dec 16, 2025 | P | 12,400 | $40.18 | Purchase +$498,232 | 525,635 | No | Form 4 |
| Akkaraju Srinivas | Oct 7, 2025 | Dec 16, 2025 | P | 4,403 | $40.97 | Purchase +$180,391 | 530,038 | No | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Dec 4, 2025 | Dec 5, 2025 | M | 65,625 | $26.05 | $1,709,531 | 174,589 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Dec 4, 2025 | Dec 5, 2025 | M | 21,093 | $18.08 | $381,361 | 195,682 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Dec 4, 2025 | Dec 5, 2025 | M | 5,607 | $4.86 | $27,250 | 201,289 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Dec 4, 2025 | Dec 5, 2025 | M | 1,281 | $7.62 | $9,761 | 202,570 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Dec 4, 2025 | Dec 5, 2025 | M | 11,250 | $10.00 | $112,500 | 213,820 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Dec 4, 2025 | Dec 5, 2025 | M | 23,571 | $15.75 | $371,243 | 237,391 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Dec 4, 2025 | Dec 5, 2025 | M | 8,035 | $35.15 | $282,430 | 245,426 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Dec 4, 2025 | Dec 5, 2025 | S | 136,462 | $45.21 | Sale −$6,169,447 | 108,964 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Dec 4, 2025 | Dec 5, 2025 | M · derivative | 65,625 | $26.05 | $1,709,531 | 4,375 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Dec 4, 2025 | Dec 5, 2025 | M · derivative | 21,093 | $18.08 | $381,361 | 1,407 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Dec 4, 2025 | Dec 5, 2025 | M · derivative | 5,607 | $4.86 | $27,250 | not reported | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Dec 4, 2025 | Dec 5, 2025 | M · derivative | 1,281 | $7.62 | $9,761 | 1,282 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Dec 4, 2025 | Dec 5, 2025 | M · derivative | 11,250 | $10.00 | $112,500 | 14,063 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Dec 4, 2025 | Dec 5, 2025 | M · derivative | 23,571 | $15.75 | $371,243 | 53,036 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Dec 4, 2025 | Dec 5, 2025 | M · derivative | 8,035 | $35.15 | $282,430 | 34,820 | Yes | Form 4 |
| Hallal DavidChief Executive Officer | Oct 8, 2025 | Oct 9, 2025 | G | 205,000 | $0.00 | $0 | 1,599,095 | No | Form 4 |
| Akkaraju Srinivas | Oct 6, 2025 | Oct 7, 2025 | P | 18,414 | $37.89 | Purchase +$697,706 | 405,828 | No | Form 4 |
| Akkaraju Srinivas | Oct 6, 2025 | Oct 7, 2025 | P | 80,863 | $38.68 | Purchase +$3,127,781 | 486,691 | No | Form 4 |
| Akkaraju Srinivas | Oct 6, 2025 | Oct 7, 2025 | P | 13,748 | $39.52 | Purchase +$543,321 | 500,439 | No | Form 4 |
| Akkaraju Srinivas | Oct 3, 2025 | Oct 7, 2025 | P | 11,011 | $35.61 | Purchase +$392,102 | 11,011 | No | Form 4 |
| Akkaraju Srinivas | Oct 3, 2025 | Oct 7, 2025 | P | 56,703 | $36.74 | Purchase +$2,083,268 | 67,714 | No | Form 4 |
| Akkaraju Srinivas | Oct 3, 2025 | Oct 7, 2025 | P | 319,700 | $37.42 | Purchase +$11,963,174 | 387,414 | No | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Sep 22, 2025 | Sep 24, 2025 | S | 3,353 | $30.67 | Sale −$102,837 | 108,964 | No | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Sep 16, 2025 | Sep 17, 2025 | S | 3,178 | $33.52 | Sale −$106,527 | 112,317 | No | Form 4 |
| Peng Katie | Sep 16, 2025 | Sep 17, 2025 | S | 930 | $32.48 | Sale −$30,206 | 33,990 | Yes | Form 4 |
| Peng Katie | Sep 16, 2025 | Sep 17, 2025 | S | 76 | $33.20 | Sale −$2,523 | 33,914 | Yes | Form 4 |
| Parlavecchio CarynCHRO | Aug 18, 2025 | Aug 19, 2025 | S | 2,178 | $31.17 | Sale −$67,888 | 155,464 | No | Form 4 |
| Flier Jeffrey S. | Jul 16, 2025 | Jul 18, 2025 | S | 11,136 | $40.02 | Sale −$445,663 | not reported | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Jul 8, 2025 | Jul 10, 2025 | S | 24,066 | $34.44 | Sale −$828,833 | 115,495 | Yes | Form 4 |
| Flier Jeffrey S. | Jun 23, 2025 | Jun 25, 2025 | M | 20,316 | $21.62 | $439,232 | 44,386 | Yes | Form 4 |
| Flier Jeffrey S. | Jun 23, 2025 | Jun 25, 2025 | S | 17,550 | $32.16 | Sale −$564,408 | 26,836 | Yes | Form 4 |
| Flier Jeffrey S. | Jun 23, 2025 | Jun 25, 2025 | S | 2,766 | $32.74 | Sale −$90,559 | 24,070 | Yes | Form 4 |
| Flier Jeffrey S. | Jun 23, 2025 | Jun 25, 2025 | S | 11,136 | $33.21 | Sale −$369,827 | 11,136 | Yes | Form 4 |
| Flier Jeffrey S. | Jun 23, 2025 | Jun 25, 2025 | M · derivative | 20,316 | $21.62 | $439,232 | not reported | Yes | Form 4 |
| Ho JunlinGENERAL COUNSEL | Jun 16, 2025 | Jun 17, 2025 | S | 7,442 | $32.00 | Sale −$238,144 | 222,569 | No | Form 4 |
| Parlavecchio CarynCHRO | Jun 16, 2025 | Jun 17, 2025 | S | 6,186 | $32.00 | Sale −$197,952 | 157,642 | No | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Jun 16, 2025 | Jun 17, 2025 | S | 3,668 | $32.00 | Sale −$117,376 | 139,561 | No | Form 4 |
| Peng Katie | Jun 16, 2025 | Jun 17, 2025 | S | 2,977 | $31.96 | Sale −$95,145 | 34,974 | Yes | Form 4 |
| Peng Katie | Jun 16, 2025 | Jun 17, 2025 | S | 54 | $32.53 | Sale −$1,757 | 34,920 | Yes | Form 4 |
| Ho JunlinGENERAL COUNSEL | Jun 9, 2025 | Jun 11, 2025 | A | 8,571 | $0.00 | $0 | 230,011 | No | Form 4 |
| Ho JunlinGENERAL COUNSEL | Jun 9, 2025 | Jun 11, 2025 | A · derivative | 11,429 | $34.07 | $389,386 | 11,429 | No | Form 4 |
| Vaishnaw AkshayPresident of R&D | May 29, 2025 | May 30, 2025 | S | 5,130 | $29.63 | Sale −$152,002 | 617,825 | Yes | Form 4 |
| Vaishnaw AkshayPresident of R&D | May 29, 2025 | May 30, 2025 | S | 1,620 | $30.01 | Sale −$48,616 | 616,205 | Yes | Form 4 |
| Reed Joshua | May 29, 2025 | May 30, 2025 | S | 4,900 | $29.68 | Sale −$145,432 | 16,232 | Yes | Form 4 |
| Reed Joshua | May 29, 2025 | May 30, 2025 | S | 500 | $30.04 | Sale −$15,020 | 15,732 | Yes | Form 4 |
| Brudnick Richard | May 29, 2025 | May 30, 2025 | S | 4,675 | $29.63 | Sale −$138,520 | 16,457 | Yes | Form 4 |
| Brudnick Richard | May 29, 2025 | May 30, 2025 | S | 1,400 | $30.00 | Sale −$42,000 | 15,057 | Yes | Form 4 |
| Gilman Michael | May 29, 2025 | May 30, 2025 | S | 630 | $29.22 | Sale −$18,409 | 57,961 | Yes | Form 4 |
| Gilman Michael | May 29, 2025 | May 30, 2025 | S | 2,745 | $29.83 | Sale −$81,883 | 55,216 | Yes | Form 4 |
| Burow Kristina | May 29, 2025 | May 30, 2025 | S | 1,000 | $29.24 | Sale −$29,240 | 25,471 | Yes | Form 4 |
| Burow Kristina | May 29, 2025 | May 30, 2025 | S | 4,400 | $29.83 | Sale −$131,252 | 21,071 | Yes | Form 4 |
| Flier Jeffrey S. | May 29, 2025 | May 30, 2025 | S | 1,100 | $29.23 | Sale −$32,153 | 29,045 | Yes | Form 4 |
| Flier Jeffrey S. | May 29, 2025 | May 30, 2025 | S | 4,975 | $29.84 | Sale −$148,454 | 24,070 | Yes | Form 4 |
| Flier Jeffrey S. | May 22, 2025 | May 23, 2025 | A | 7,632 | $0.00 | $0 | 30,145 | No | Form 4 |
| Flier Jeffrey S. | May 22, 2025 | May 23, 2025 | A · derivative | 9,206 | $30.46 | $280,415 | 9,206 | No | Form 4 |
| Gilman Michael | May 22, 2025 | May 23, 2025 | A | 7,632 | $0.00 | $0 | 58,591 | No | Form 4 |
| Gilman Michael | May 22, 2025 | May 23, 2025 | A · derivative | 9,206 | $30.46 | $280,415 | 9,206 | No | Form 4 |
| Peng Katie | May 22, 2025 | May 23, 2025 | A | 7,632 | $0.00 | $0 | 37,951 | No | Form 4 |
| Peng Katie | May 22, 2025 | May 23, 2025 | A · derivative | 9,206 | $30.46 | $280,415 | 9,206 | No | Form 4 |
| Akkaraju Srinivas | May 22, 2025 | May 23, 2025 | A | 7,632 | $0.00 | $0 | 21,132 | No | Form 4 |
| Akkaraju Srinivas | May 22, 2025 | May 23, 2025 | A · derivative | 9,206 | $30.46 | $280,415 | 9,206 | No | Form 4 |
| Burow Kristina | May 22, 2025 | May 23, 2025 | A | 7,632 | $0.00 | $0 | 26,471 | No | Form 4 |
| Burow Kristina | May 22, 2025 | May 23, 2025 | A · derivative | 9,206 | $30.46 | $280,415 | 9,206 | No | Form 4 |
| Reed Joshua | May 22, 2025 | May 23, 2025 | A | 7,632 | $0.00 | $0 | 21,132 | No | Form 4 |
| Reed Joshua | May 22, 2025 | May 23, 2025 | A · derivative | 9,206 | $30.46 | $280,415 | 9,206 | No | Form 4 |
| Brudnick Richard | May 22, 2025 | May 23, 2025 | A | 7,632 | $0.00 | $0 | 21,132 | No | Form 4 |
| Brudnick Richard | May 22, 2025 | May 23, 2025 | A · derivative | 9,206 | $30.46 | $280,415 | 9,206 | No | Form 4 |
| Hallal DavidChief Executive Officer | May 2, 2025 | May 6, 2025 | A · derivative | 275,167 | $32.91 | $9,055,746 | 275,167 | No | Form 4 |
| Sinha VikasChief Financial Officer | May 2, 2025 | May 6, 2025 | A · derivative | 110,067 | $32.91 | $3,622,305 | 110,067 | No | Form 4 |
| Vaishnaw AkshayPresident of R&D | May 2, 2025 | May 6, 2025 | A · derivative | 110,067 | $32.91 | $3,622,305 | 110,067 | No | Form 4 |
| Woods KeithChief Operating Officer | May 2, 2025 | May 6, 2025 | A · derivative | 110,067 | $32.91 | $3,622,305 | 110,067 | No | Form 4 |
| Sinha VikasChief Financial Officer | Apr 27, 2025 | Apr 29, 2025 | A | 100,000 | $0.00 | $0 | 100,000 | No | Form 4 |
| Sinha VikasChief Financial Officer | Apr 27, 2025 | Apr 29, 2025 | A | 500,000 | $0.00 | $0 | 600,000 | No | Form 4 |
| Hallal DavidCEO | Apr 27, 2025 | Apr 29, 2025 | A | 250,000 | $0.00 | $0 | 554,095 | No | Form 4 |
| Hallal DavidCEO | Apr 27, 2025 | Apr 29, 2025 | A | 1,250,000 | $0.00 | $0 | 1,804,095 | No | Form 4 |
| Vaishnaw AkshayPresident of R&D | Apr 27, 2025 | Apr 29, 2025 | A | 100,000 | $0.00 | $0 | 122,955 | No | Form 4 |
| Vaishnaw AkshayPresident of R&D | Apr 27, 2025 | Apr 29, 2025 | A | 500,000 | $0.00 | $0 | 622,955 | No | Form 4 |
| Woods KeithChief Operating Officer | Apr 27, 2025 | Apr 29, 2025 | A | 100,000 | $0.00 | $0 | 100,000 | No | Form 4 |
| Woods KeithChief Operating Officer | Apr 27, 2025 | Apr 29, 2025 | A | 500,000 | $0.00 | $0 | 600,000 | No | Form 4 |
| Sacco TraceyChief Commercial Officer | Apr 25, 2025 | Apr 29, 2025 | M | 5,000 | $10.00 | $50,000 | 76,250 | Yes | Form 4 |
| Sacco TraceyChief Commercial Officer | Apr 25, 2025 | Apr 29, 2025 | S | 4,916 | $32.81 | Sale −$161,294 | 71,834 | Yes | Form 4 |
| Sacco TraceyChief Commercial Officer | Apr 25, 2025 | Apr 29, 2025 | S | 84 | $33.49 | Sale −$2,813 | 71,750 | Yes | Form 4 |
| Sacco TraceyChief Commercial Officer | Apr 25, 2025 | Apr 29, 2025 | M · derivative | 5,000 | $10.00 | $50,000 | 185,000 | Yes | Form 4 |
| Moore ErinInterim PFO and PAO | Mar 24, 2025 | Mar 25, 2025 | M | 5,000 | $23.86 | $119,300 | 87,609 | Yes | Form 4 |
| Moore ErinInterim PFO and PAO | Mar 24, 2025 | Mar 25, 2025 | M | 8,564 | $13.52 | $115,785 | 96,173 | Yes | Form 4 |
| Moore ErinInterim PFO and PAO | Mar 24, 2025 | Mar 25, 2025 | S | 13,564 | $33.12 | Sale −$449,240 | 82,609 | Yes | Form 4 |
| Moore ErinInterim PFO and PAO | Mar 24, 2025 | Mar 25, 2025 | M · derivative | 5,000 | $23.86 | $119,300 | 11,764 | Yes | Form 4 |
| Moore ErinInterim PFO and PAO | Mar 24, 2025 | Mar 25, 2025 | M · derivative | 8,564 | $13.52 | $115,785 | 40,724 | Yes | Form 4 |
| Sacco TraceyChief Commercial Officer | Mar 24, 2025 | Mar 25, 2025 | M | 5,000 | $10.00 | $50,000 | 78,250 | Yes | Form 4 |
| Sacco TraceyChief Commercial Officer | Mar 24, 2025 | Mar 25, 2025 | S | 1,500 | $33.70 | Sale −$50,550 | 76,750 | Yes | Form 4 |
| Sacco TraceyChief Commercial Officer | Mar 24, 2025 | Mar 25, 2025 | S | 5,000 | $32.89 | Sale −$164,450 | 71,750 | Yes | Form 4 |
| Sacco TraceyChief Commercial Officer | Mar 24, 2025 | Mar 25, 2025 | M · derivative | 5,000 | $10.00 | $50,000 | 190,000 | Yes | Form 4 |
| Peng Katie | Mar 17, 2025 | Mar 19, 2025 | S | 1,006 | $34.42 | Sale −$34,627 | 30,319 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Mar 10, 2025 | Mar 12, 2025 | M | 21,690 | $13.83 | $299,973 | 162,430 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Mar 10, 2025 | Mar 12, 2025 | M | 43,122 | $18.08 | $779,646 | 205,552 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Mar 10, 2025 | Mar 12, 2025 | M | 24,915 | $4.86 | $121,087 | 230,467 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Mar 10, 2025 | Mar 12, 2025 | M | 5,313 | $10.00 | $53,130 | 235,780 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Mar 10, 2025 | Mar 12, 2025 | M | 17,857 | $15.75 | $281,248 | 253,637 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Mar 10, 2025 | Mar 12, 2025 | S | 112,897 | $35.82 | Sale −$4,043,971 | 140,740 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Mar 10, 2025 | Mar 12, 2025 | S | 29,395 | $34.87 | Sale −$1,025,004 | 111,345 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Mar 10, 2025 | Mar 12, 2025 | M · derivative | 21,690 | $13.83 | $299,973 | not reported | Yes | Form 4 |
| Myles Edward HCOO & CFO | Mar 10, 2025 | Mar 12, 2025 | M · derivative | 43,122 | $18.08 | $779,646 | 14,378 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Mar 10, 2025 | Mar 12, 2025 | M · derivative | 24,915 | $4.86 | $121,087 | 12,462 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Mar 10, 2025 | Mar 12, 2025 | M · derivative | 5,313 | $10.00 | $53,130 | 42,500 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Mar 10, 2025 | Mar 12, 2025 | M · derivative | 17,857 | $15.75 | $281,248 | 53,573 | Yes | Form 4 |
| Sacco TraceyChief Commercial Officer | Mar 10, 2025 | Mar 12, 2025 | A | 27,855 | $0.00 | $0 | 73,250 | No | Form 4 |
| Sacco TraceyChief Commercial Officer | Mar 10, 2025 | Mar 12, 2025 | A · derivative | 37,145 | $35.15 | $1,305,647 | 37,145 | No | Form 4 |
| Ho JunlinGENERAL COUNSEL | Mar 10, 2025 | Mar 12, 2025 | A | 32,145 | $0.00 | $0 | 221,440 | No | Form 4 |
| Ho JunlinGENERAL COUNSEL | Mar 10, 2025 | Mar 12, 2025 | A · derivative | 42,855 | $35.15 | $1,506,353 | 42,855 | No | Form 4 |
| Backstrom Jay T.CHIEF EXECUTIVE OFFICER | Mar 10, 2025 | Mar 12, 2025 | A | 113,570 | $0.00 | $0 | 425,561 | No | Form 4 |
| Backstrom Jay T.CHIEF EXECUTIVE OFFICER | Mar 10, 2025 | Mar 12, 2025 | A · derivative | 151,430 | $35.15 | $5,322,765 | 151,430 | No | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Mar 10, 2025 | Mar 12, 2025 | A | 34,285 | $0.00 | $0 | 101,485 | No | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Mar 10, 2025 | Mar 12, 2025 | A · derivative | 45,715 | $35.15 | $1,606,882 | 45,715 | No | Form 4 |
| Parlavecchio CarynCHRO | Mar 10, 2025 | Mar 12, 2025 | A | 23,570 | $0.00 | $0 | 163,828 | No | Form 4 |
| Parlavecchio CarynCHRO | Mar 10, 2025 | Mar 12, 2025 | A · derivative | 31,430 | $35.15 | $1,104,765 | 31,430 | No | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Mar 10, 2025 | Mar 12, 2025 | A | 32,145 | $0.00 | $0 | 143,229 | No | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Mar 10, 2025 | Mar 12, 2025 | A · derivative | 42,855 | $35.15 | $1,506,353 | 42,855 | No | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Feb 19, 2025 | Feb 20, 2025 | M | 16,818 | $4.86 | $81,735 | 148,104 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Feb 19, 2025 | Feb 20, 2025 | M | 2,562 | $7.62 | $19,522 | 150,666 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Feb 19, 2025 | Feb 20, 2025 | M | 11,250 | $10.00 | $112,500 | 161,916 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Feb 19, 2025 | Feb 20, 2025 | M | 17,678 | $15.75 | $278,429 | 179,594 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Feb 19, 2025 | Feb 20, 2025 | S | 39,967 | $37.20 | Sale −$1,486,772 | 139,627 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Feb 19, 2025 | Feb 20, 2025 | S | 8,341 | $37.56 | Sale −$313,288 | 131,286 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Feb 19, 2025 | Feb 20, 2025 | S | 20,202 | $37.74 | Sale −$762,423 | 111,084 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Feb 19, 2025 | Feb 20, 2025 | M · derivative | 16,818 | $4.86 | $81,735 | 5,607 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Feb 19, 2025 | Feb 20, 2025 | M · derivative | 2,562 | $7.62 | $19,522 | 2,563 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Feb 19, 2025 | Feb 20, 2025 | M · derivative | 11,250 | $10.00 | $112,500 | 25,313 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Feb 19, 2025 | Feb 20, 2025 | M · derivative | 17,678 | $15.75 | $278,429 | 76,607 | Yes | Form 4 |
| Backstrom Jay T.CHIEF EXECUTIVE OFFICER | Feb 18, 2025 | Feb 20, 2025 | S | 18,372 | $36.83 | Sale −$676,641 | 311,991 | No | Form 4 |
| Ho JunlinGENERAL COUNSEL | Feb 18, 2025 | Feb 20, 2025 | S | 5,742 | $36.83 | Sale −$211,478 | 189,295 | No | Form 4 |
| Myles Edward HCOO & CFO | Feb 18, 2025 | Feb 20, 2025 | S | 7,809 | $36.83 | Sale −$287,605 | 140,740 | No | Form 4 |
| Parlavecchio CarynCHRO | Feb 18, 2025 | Feb 20, 2025 | S | 5,296 | $36.83 | Sale −$195,052 | 140,258 | No | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Feb 18, 2025 | Feb 20, 2025 | S | 4,135 | $36.83 | Sale −$152,292 | 131,286 | Yes | Form 4 |
| Ho JunlinGENERAL COUNSEL | Jan 16, 2025 | Jan 21, 2025 | S | 9,039 | $44.20 | Sale −$399,524 | 195,037 | No | Form 4 |
| Myles Edward HCOO & CFO | Jan 16, 2025 | Jan 21, 2025 | S | 12,539 | $44.20 | Sale −$554,224 | 148,549 | No | Form 4 |
| Parlavecchio CarynCHRO | Jan 16, 2025 | Jan 21, 2025 | S | 6,434 | $44.20 | Sale −$284,383 | 145,554 | No | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Jan 16, 2025 | Jan 21, 2025 | S | 7,347 | $44.20 | Sale −$324,737 | 135,421 | No | Form 4 |
| Sacco TraceyChief Commercial Officer | Jan 16, 2025 | Jan 21, 2025 | S | 3,890 | $44.20 | Sale −$171,938 | 45,395 | No | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Jan 16, 2025 | Jan 21, 2025 | S | 5,655 | $44.20 | Sale −$249,951 | 67,200 | No | Form 4 |
| Backstrom Jay T.CHIEF EXECUTIVE OFFICER | Jan 16, 2025 | Jan 21, 2025 | S | 22,308 | $44.20 | Sale −$986,014 | 330,363 | No | Form 4 |
| Invus Global Management, LLC | Dec 10, 2024 | Dec 12, 2024 | S | 1,600,000 | $41.65 | Sale −$66,640,000 | 9,250,005 | No | Form 4 |
| Invus Public Equities Advisors, LLC | Nov 25, 2024 | Nov 27, 2024 | S | 208,272 | $37.63 | Sale −$7,837,275 | 11,051,166 | No | Form 4 |
| Invus Public Equities Advisors, LLC | Nov 25, 2024 | Nov 27, 2024 | S | 43,887 | $38.43 | Sale −$1,686,577 | 11,007,279 | No | Form 4 |
| Invus Public Equities Advisors, LLC | Nov 25, 2024 | Nov 27, 2024 | S | 126,442 | $39.51 | Sale −$4,995,723 | 10,880,837 | No | Form 4 |
| Invus Public Equities Advisors, LLC | Nov 25, 2024 | Nov 27, 2024 | S | 30,683 | $40.14 | Sale −$1,231,616 | 10,850,154 | No | Form 4 |
| Invus Public Equities Advisors, LLC | Nov 25, 2024 | Nov 27, 2024 | S | 149 | $40.98 | Sale −$6,106 | 10,850,005 | No | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Nov 25, 2024 | Nov 26, 2024 | M | 6,375 | $8.59 | $54,761 | 79,230 | Yes | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Nov 25, 2024 | Nov 26, 2024 | S | 1,000 | $38.04 | Sale −$38,040 | 78,230 | Yes | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Nov 25, 2024 | Nov 26, 2024 | S | 2,100 | $39.25 | Sale −$82,425 | 76,130 | Yes | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Nov 25, 2024 | Nov 26, 2024 | S | 3,075 | $39.93 | Sale −$122,785 | 73,055 | Yes | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Nov 25, 2024 | Nov 26, 2024 | S | 200 | $40.72 | Sale −$8,144 | 72,855 | Yes | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Nov 25, 2024 | Nov 26, 2024 | M · derivative | 6,375 | $8.59 | $54,761 | 130,000 | Yes | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Nov 22, 2024 | Nov 26, 2024 | M | 2,145 | $8.59 | $18,426 | 75,000 | Yes | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Nov 22, 2024 | Nov 26, 2024 | S | 2,145 | $30.01 | Sale −$64,371 | 72,855 | Yes | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Nov 22, 2024 | Nov 26, 2024 | M · derivative | 2,145 | $8.59 | $18,426 | 136,375 | Yes | Form 4 |
| Gilman Michael | Nov 12, 2024 | Nov 13, 2024 | G | 37,459 | not reported | not reported | not reported | No | Form 4 |
| Gilman Michael | Nov 12, 2024 | Nov 13, 2024 | G | 37,459 | not reported | not reported | 50,959 | No | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Nov 11, 2024 | Nov 13, 2024 | M | 2,105 | $8.59 | $18,082 | 74,960 | Yes | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Nov 11, 2024 | Nov 13, 2024 | S | 2,105 | $30.00 | Sale −$63,150 | 72,855 | Yes | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Nov 11, 2024 | Nov 13, 2024 | M · derivative | 2,105 | $8.59 | $18,082 | 138,520 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Oct 8, 2024 | Oct 10, 2024 | M | 37,187 | $10.00 | $371,870 | 198,275 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Oct 8, 2024 | Oct 10, 2024 | S | 37,187 | $34.90 | Sale −$1,297,826 | 161,088 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Oct 8, 2024 | Oct 10, 2024 | M · derivative | 37,187 | $10.00 | $371,870 | 47,813 | Yes | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Oct 7, 2024 | Oct 7, 2024 | M | 109,375 | $8.59 | $939,531 | 182,230 | Yes | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Oct 7, 2024 | Oct 7, 2024 | S | 67,448 | $25.59 | Sale −$1,725,994 | 114,782 | Yes | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Oct 7, 2024 | Oct 7, 2024 | S | 2,552 | $26.22 | Sale −$66,913 | 112,230 | Yes | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Oct 7, 2024 | Oct 7, 2024 | S | 39,375 | $30.06 | Sale −$1,183,613 | 72,855 | Yes | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Oct 7, 2024 | Oct 7, 2024 | M · derivative | 109,375 | $8.59 | $939,531 | 140,625 | Yes | Form 4 |
| Sacco TraceyCHIEF COMMERCIAL OFFICER | Oct 7, 2024 | Oct 7, 2024 | M | 30,000 | $10.00 | $300,000 | 79,285 | Yes | Form 4 |
| Sacco TraceyCHIEF COMMERCIAL OFFICER | Oct 7, 2024 | Oct 7, 2024 | S | 28,036 | $25.58 | Sale −$717,161 | 51,249 | Yes | Form 4 |
| Sacco TraceyCHIEF COMMERCIAL OFFICER | Oct 7, 2024 | Oct 7, 2024 | S | 1,964 | $26.23 | Sale −$51,516 | 49,285 | Yes | Form 4 |
| Sacco TraceyCHIEF COMMERCIAL OFFICER | Oct 7, 2024 | Oct 7, 2024 | M · derivative | 30,000 | $10.00 | $300,000 | 140,625 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Oct 7, 2024 | Oct 7, 2024 | M | 206,240 | $13.83 | $2,852,299 | 367,328 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Oct 7, 2024 | Oct 7, 2024 | S | 111,972 | $25.61 | Sale −$2,867,603 | 255,356 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Oct 7, 2024 | Oct 7, 2024 | S | 37,206 | $26.83 | Sale −$998,237 | 218,150 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Oct 7, 2024 | Oct 7, 2024 | S | 25,812 | $27.27 | Sale −$703,893 | 192,338 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Oct 7, 2024 | Oct 7, 2024 | S | 31,250 | $29.05 | Sale −$907,813 | 161,088 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Oct 7, 2024 | Oct 7, 2024 | M · derivative | 165,810 | $13.83 | $2,293,152 | not reported | Yes | Form 4 |
| Akkaraju Srinivas | Oct 7, 2024 | Oct 7, 2024 | S | 510,000 | $27.50 | Sale −$14,025,000 | 6,278,609 | Yes | Form 4 |
| Akkaraju Srinivas | Oct 7, 2024 | Oct 7, 2024 | S | 510,000 | $30.00 | Sale −$15,300,000 | 5,768,609 | Yes | Form 4 |
| Akkaraju Srinivas | Oct 7, 2024 | Oct 7, 2024 | S | 155,713 | $32.50 | Sale −$5,060,673 | 5,612,896 | Yes | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Sep 16, 2024 | Sep 19, 2024 | S | 1,936 | $8.58 | Sale −$16,611 | 142,768 | No | Form 4 |
| Parlavecchio CarynCHRO | Aug 16, 2024 | Aug 19, 2024 | S | 1,451 | $9.33 | Sale −$13,538 | 151,988 | No | Form 4 |
| Hallal David | Jun 27, 2024 | Jul 1, 2024 | A | 13,500 | $0.00 | $0 | 304,095 | No | Form 4 |
| Hallal David | Jun 27, 2024 | Jul 1, 2024 | A · derivative | 18,000 | $8.36 | $150,480 | 18,000 | No | Form 4 |
| Akkaraju Srinivas | Jun 27, 2024 | Jul 1, 2024 | A | 13,500 | $0.00 | $0 | 13,500 | No | Form 4 |
| Akkaraju Srinivas | Jun 27, 2024 | Jul 1, 2024 | A · derivative | 18,000 | $8.36 | $150,480 | 18,000 | No | Form 4 |
| Brudnick Richard | Jun 27, 2024 | Jul 1, 2024 | A | 13,500 | $0.00 | $0 | 13,500 | No | Form 4 |
| Brudnick Richard | Jun 27, 2024 | Jul 1, 2024 | A · derivative | 18,000 | $8.36 | $150,480 | 18,000 | No | Form 4 |
| Flier Jeffrey S. | Jun 27, 2024 | Jul 1, 2024 | A | 13,500 | $0.00 | $0 | 22,513 | No | Form 4 |
| Flier Jeffrey S. | Jun 27, 2024 | Jul 1, 2024 | A · derivative | 18,000 | $8.36 | $150,480 | 18,000 | No | Form 4 |
| Gilman Michael | Jun 27, 2024 | Jul 1, 2024 | A | 13,500 | $0.00 | $0 | 13,500 | No | Form 4 |
| Gilman Michael | Jun 27, 2024 | Jul 1, 2024 | A · derivative | 18,000 | $8.36 | $150,480 | 18,000 | No | Form 4 |
| Peng Katie | Jun 27, 2024 | Jul 1, 2024 | A | 4,500 | $0.00 | $0 | 31,325 | No | Form 4 |
| Peng Katie | Jun 27, 2024 | Jul 1, 2024 | A · derivative | 6,000 | $8.36 | $50,160 | 6,000 | No | Form 4 |
| Reed Joshua | Jun 27, 2024 | Jul 1, 2024 | A | 13,500 | $0.00 | $0 | 13,500 | No | Form 4 |
| Reed Joshua | Jun 27, 2024 | Jul 1, 2024 | A · derivative | 18,000 | $8.36 | $150,480 | 18,000 | No | Form 4 |
| Vaishnaw Akshay | Jun 27, 2024 | Jul 1, 2024 | A | 13,500 | $0.00 | $0 | 22,955 | No | Form 4 |
| Vaishnaw Akshay | Jun 27, 2024 | Jul 1, 2024 | A · derivative | 18,000 | $8.36 | $150,480 | 18,000 | No | Form 4 |
| Burow Kristina | Jun 27, 2024 | Jul 1, 2024 | A | 13,500 | $0.00 | $0 | 18,839 | No | Form 4 |
| Burow Kristina | Jun 27, 2024 | Jul 1, 2024 | A · derivative | 18,000 | $8.36 | $150,480 | 18,000 | No | Form 4 |
| Ho JunlinGENERAL COUNSEL | Jun 17, 2024 | Jun 18, 2024 | S | 4,695 | $8.98 | Sale −$42,161 | 204,076 | No | Form 4 |
| Myles Edward HCOO & CFO | Jun 17, 2024 | Jun 18, 2024 | S | 9,458 | $8.98 | Sale −$84,933 | 201,518 | No | Form 4 |
| Parlavecchio CarynCHRO | Jun 17, 2024 | Jun 18, 2024 | S | 4,305 | $8.98 | Sale −$38,659 | 153,439 | No | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Jun 17, 2024 | Jun 18, 2024 | S | 2,315 | $8.99 | Sale −$20,812 | 144,704 | No | Form 4 |
| Nashat Amir | May 9, 2024 | May 13, 2024 | J | 472,394 | $0.00 | $0 | 1,650,953 | No | Form 4 |
| Nashat Amir | May 9, 2024 | May 13, 2024 | J | 98,257 | $0.00 | $0 | 98,257 | No | Form 4 |
| Nashat Amir | May 9, 2024 | May 13, 2024 | J | 98,257 | $0.00 | $0 | not reported | No | Form 4 |
| Nashat Amir | May 9, 2024 | May 13, 2024 | J | 13,096 | $0.00 | $0 | 38,602 | No | Form 4 |
| Nashat Amir | May 9, 2024 | May 13, 2024 | J | 27,606 | $0.00 | $0 | 96,474 | No | Form 4 |
| Nashat Amir | May 9, 2024 | May 13, 2024 | J | 322 | $0.00 | $0 | 1,469 | No | Form 4 |
| Nashat Amir | May 9, 2024 | May 13, 2024 | J | 276 | $0.00 | $0 | 276 | No | Form 4 |
| Nashat Amir | May 9, 2024 | May 13, 2024 | J | 276 | $0.00 | $0 | not reported | No | Form 4 |
| Nashat Amir | May 9, 2024 | May 13, 2024 | J | 37 | $0.00 | $0 | 38,639 | No | Form 4 |
| Peng Katie | Apr 9, 2024 | Apr 11, 2024 | A | 26,825 | $0.00 | $0 | 26,825 | No | Form 4 |
| Peng Katie | Apr 9, 2024 | Apr 11, 2024 | A · derivative | 35,767 | $14.82 | $530,067 | 35,767 | No | Form 4 |
| Myles Edward HCOO & CFO | Feb 16, 2024 | Feb 21, 2024 | S | 4,744 | $15.74 | Sale −$74,671 | 210,976 | No | Form 4 |
| Backstrom Jay T.CHIEF EXECUTIVE OFFICER | Feb 16, 2024 | Feb 20, 2024 | S | 11,614 | $15.74 | Sale −$182,804 | 352,671 | No | Form 4 |
| Ho JunlinGENERAL COUNSEL | Feb 16, 2024 | Feb 20, 2024 | S | 3,489 | $15.74 | Sale −$54,917 | 208,771 | No | Form 4 |
| Parlavecchio CarynCHRO | Feb 16, 2024 | Feb 20, 2024 | S | 3,751 | $15.74 | Sale −$59,041 | 157,744 | No | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Feb 16, 2024 | Feb 20, 2024 | S | 2,512 | $15.74 | Sale −$39,539 | 147,019 | No | Form 4 |
| Ho JunlinGENERAL COUNSEL | Feb 12, 2024 | Feb 13, 2024 | A | 57,855 | $0.00 | $0 | 212,260 | No | Form 4 |
| Ho JunlinGENERAL COUNSEL | Feb 12, 2024 | Feb 13, 2024 | A · derivative | 77,145 | $15.75 | $1,215,034 | 77,145 | No | Form 4 |
| Myles Edward HCOO & CFO | Feb 12, 2024 | Feb 13, 2024 | A | 53,570 | $0.00 | $0 | 215,720 | No | Form 4 |
| Myles Edward HCOO & CFO | Feb 12, 2024 | Feb 13, 2024 | A · derivative | 71,430 | $15.75 | $1,125,023 | 71,430 | No | Form 4 |
| Parlavecchio CarynCHRO | Feb 12, 2024 | Feb 13, 2024 | A | 47,145 | $0.00 | $0 | 161,495 | No | Form 4 |
| Parlavecchio CarynCHRO | Feb 12, 2024 | Feb 13, 2024 | A · derivative | 62,855 | $15.75 | $989,966 | 62,855 | No | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Feb 12, 2024 | Feb 13, 2024 | A | 70,715 | $0.00 | $0 | 149,531 | No | Form 4 |
| Qatanani MoCHIEF SCIENTIFIC OFFICER | Feb 12, 2024 | Feb 13, 2024 | A · derivative | 94,285 | $15.75 | $1,484,989 | 94,285 | No | Form 4 |
| Sacco TraceyCHIEF COMMERCIAL OFFICER | Feb 12, 2024 | Feb 13, 2024 | A | 49,285 | $0.00 | $0 | 49,285 | No | Form 4 |
| Sacco TraceyCHIEF COMMERCIAL OFFICER | Feb 12, 2024 | Feb 13, 2024 | A · derivative | 65,715 | $15.75 | $1,035,011 | 65,715 | No | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Feb 12, 2024 | Feb 13, 2024 | A | 72,855 | $0.00 | $0 | 72,855 | No | Form 4 |
| Marantz Jing L.CHIEF MEDICAL OFFICER | Feb 12, 2024 | Feb 13, 2024 | A · derivative | 97,145 | $15.75 | $1,530,034 | 97,145 | No | Form 4 |
| Backstrom Jay T.CHIEF EXECUTIVE OFFICER | Feb 12, 2024 | Feb 13, 2024 | A | 214,285 | $0.00 | $0 | 364,285 | No | Form 4 |
| Backstrom Jay T.CHIEF EXECUTIVE OFFICER | Feb 12, 2024 | Feb 13, 2024 | A · derivative | 285,715 | $15.75 | $4,500,011 | 285,715 | No | Form 4 |
| Ho JunlinGENERAL COUNSEL | Jan 16, 2024 | Jan 18, 2024 | S | 4,186 | $15.93 | Sale −$66,683 | 154,405 | No | Form 4 |
| Myles Edward HCOO & CFO | Jan 16, 2024 | Jan 18, 2024 | S | 6,634 | $15.93 | Sale −$105,680 | 162,150 | No | Form 4 |
| Parlavecchio CarynCHRO | Jan 16, 2024 | Jan 18, 2024 | S | 2,849 | $15.93 | Sale −$45,385 | 114,350 | No | Form 4 |
| Qatanani MoSVP AND HEAD OF RESEARCH | Jan 16, 2024 | Jan 18, 2024 | S | 2,002 | $15.93 | Sale −$31,892 | 78,816 | No | Form 4 |
| Myles Edward HCOO & CFO | Dec 29, 2023 | Dec 29, 2023 | M | 12,459 | $4.86 | $60,551 | 181,243 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Dec 29, 2023 | Dec 29, 2023 | S | 12,159 | $18.82 | Sale −$228,832 | 169,084 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Dec 29, 2023 | Dec 29, 2023 | S | 300 | $19.51 | Sale −$5,853 | 168,784 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Dec 29, 2023 | Dec 29, 2023 | M · derivative | 24,914 | $4.86 | $121,082 | 49,836 | Yes | Form 4 |
| Nashat Amir | Dec 27, 2023 | Dec 29, 2023 | G | 21,333 | $0.00 | $0 | 25,506 | No | Form 4 |
| Burow Kristina | Dec 21, 2023 | Dec 26, 2023 | J | 291,906 | $0.00 | $0 | 2,345,711 | No | Form 4 |
| Burow Kristina | Dec 21, 2023 | Dec 26, 2023 | J | 5,339 | $0.00 | $0 | 5,339 | No | Form 4 |
| Qatanani MoSVP AND HEAD OF RESEARCH | Dec 14, 2023 | Dec 15, 2023 | M | 8,437 | $10.00 | $84,370 | 105,480 | No | Form 4 |
| Qatanani MoSVP AND HEAD OF RESEARCH | Dec 14, 2023 | Dec 15, 2023 | S | 24,662 | $18.18 | Sale −$448,355 | 80,818 | No | Form 4 |
| Qatanani MoSVP AND HEAD OF RESEARCH | Dec 14, 2023 | Dec 15, 2023 | M · derivative | 8,437 | $10.00 | $84,370 | 36,563 | No | Form 4 |
| Nashat Amir | Dec 13, 2023 | Dec 15, 2023 | J | 944,789 | $0.00 | $0 | 2,123,347 | No | Form 4 |
| Nashat Amir | Dec 13, 2023 | Dec 15, 2023 | J | 196,520 | $0.00 | $0 | 196,520 | No | Form 4 |
| Nashat Amir | Dec 13, 2023 | Dec 15, 2023 | J | 196,520 | $0.00 | $0 | not reported | No | Form 4 |
| Nashat Amir | Dec 13, 2023 | Dec 15, 2023 | J | 26,192 | $0.00 | $0 | 46,766 | No | Form 4 |
| Nashat Amir | Dec 13, 2023 | Dec 15, 2023 | J | 55,211 | $0.00 | $0 | 124,080 | No | Form 4 |
| Nashat Amir | Dec 13, 2023 | Dec 15, 2023 | J | 643 | $0.00 | $0 | 1,147 | No | Form 4 |
| Nashat Amir | Dec 13, 2023 | Dec 15, 2023 | J | 548 | $0.00 | $0 | 548 | No | Form 4 |
| Nashat Amir | Dec 13, 2023 | Dec 15, 2023 | J | 548 | $0.00 | $0 | not reported | No | Form 4 |
| Nashat Amir | Dec 13, 2023 | Dec 15, 2023 | J | 73 | $0.00 | $0 | 46,839 | No | Form 4 |
| Myles Edward HCOO & CFO | Dec 7, 2023 | Dec 8, 2023 | M | 24,914 | $4.86 | $121,082 | 193,698 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Dec 7, 2023 | Dec 8, 2023 | S | 24,914 | $17.53 | Sale −$436,742 | 168,784 | Yes | Form 4 |
| Myles Edward HCOO & CFO | Dec 7, 2023 | Dec 8, 2023 | M · derivative | 24,914 | $4.86 | $121,082 | 49,836 | Yes | Form 4 |
| Nashat Amir | Nov 20, 2023 | Nov 22, 2023 | J | 472,394 | $0.00 | $0 | 3,068,136 | No | Form 4 |
| Nashat Amir | Nov 20, 2023 | Nov 22, 2023 | J | 98,261 | $0.00 | $0 | 98,261 | No | Form 4 |
| Nashat Amir | Nov 20, 2023 | Nov 22, 2023 | J | 98,261 | $0.00 | $0 | not reported | No | Form 4 |
| Nashat Amir | Nov 20, 2023 | Nov 22, 2023 | J | 13,096 | $0.00 | $0 | 20,537 | No | Form 4 |
| Nashat Amir | Nov 20, 2023 | Nov 22, 2023 | J | 27,606 | $0.00 | $0 | 179,291 | No | Form 4 |
| Nashat Amir | Nov 20, 2023 | Nov 22, 2023 | J | 322 | $0.00 | $0 | 504 | No | Form 4 |
| Nashat Amir | Nov 20, 2023 | Nov 22, 2023 | J | 276 | $0.00 | $0 | 276 | No | Form 4 |
| Nashat Amir | Nov 20, 2023 | Nov 22, 2023 | J | 276 | $0.00 | $0 | not reported | No | Form 4 |
| Nashat Amir | Nov 20, 2023 | Nov 22, 2023 | J | 37 | $0.00 | $0 | 20,574 | No | Form 4 |
| Myles Edward HCOO & CFO | Nov 2, 2023 | Nov 3, 2023 | S | 35,007 | $12.51 | Sale −$437,938 | 168,784 | Yes | Form 4 |
| Samsara BioCapital GP, LLC | Oct 16, 2023 | Oct 18, 2023 | P | 2,189,781 | $6.85 | Purchase +$15,000,000 | 6,788,609 | No | Form 4 |
| Akkaraju Srinivas | Oct 16, 2023 | Oct 18, 2023 | P | 2,189,781 | $6.85 | Purchase +$15,000,000 | 6,788,609 | No | Form 4 |
| Wittouck Amaury | Oct 12, 2023 | Oct 16, 2023 | P | 2,189,781 | $6.85 | Purchase +$15,000,000 | 11,249,288 | No | Form 4 |
| Wittouck Amaury | Oct 12, 2023 | Oct 16, 2023 | P | 10,150 | $8.55 | Purchase +$86,783 | 11,259,438 | No | Form 4 |