Opaleye Management Inc.insider trades
In SEC Form 4 filings, Opaleye Management Inc. is listed as 10% owner of Grace Therapeutics, Inc. (GRCE), 10% owner of Alpha Cognition Inc. (ACOG) and 10% owner of Sol-Gel Technologies Ltd. (SLGL). In the last 90 days, Opaleye Management Inc. bought $5.99M across 3 companies on the open market and sold none. The largest purchase was $1.38M of Sol-Gel Technologies Ltd. (SLGL) on Aug 28. Took part in a cluster buy; the latest at Grace Therapeutics, Inc. (GRCE), where 2 insiders bought within 14 days, ending Sep 21.
Companies and roles
Cluster buys
- GRCE: 2 insiders bought $266.4K between Sep 8 – Sep 21.
Form 4 historysince 2026-08-31
Dashed line = amended filing (Form 4/A)
| Company | Traded | Filed | Type | Shares | Price | Value | Owned after | 10b5-1 plan | Filing |
|---|---|---|---|---|---|---|---|---|---|
| GRCEGrace Therapeutics, Inc. | Oct 19 | Oct 21 | P | 4,256 | $1.88 | Purchase +$8,001 | 2,948,610 | No | Form 4 |
| ACOGAlpha Cognition Inc. | Oct 16 | Oct 19 | P | 14,283 | $8.23 | Purchase +$117,602 | 3,259,894 | No | Form 4 |
| ACOGAlpha Cognition Inc. | Oct 15 | Oct 19 | P | 22,657 | $8.43 | Purchase +$190,974 | 3,245,611 | No | Form 4 |
| GRCEGrace Therapeutics, Inc. | Oct 16 | Oct 16 | P | 36,347 | $1.89 | Purchase +$68,758 | 2,944,354 | No | Form 4 |
| GRCEGrace Therapeutics, Inc. | Oct 15 | Oct 16 | P | 23,485 | $1.95 | Purchase +$45,685 | 2,908,007 | No | Form 4 |
| GRCEGrace Therapeutics, Inc. | Oct 14 | Oct 16 | P | 11,233 | $1.93 | Purchase +$21,735 | 2,884,522 | No | Form 4 |
| GRCEGrace Therapeutics, Inc. | Oct 12 | Oct 13 | P | 7,215 | $2.02 | Purchase +$14,574 | 2,873,289 | No | Form 4 |
| GRCEGrace Therapeutics, Inc. | Oct 9 | Oct 13 | P | 5,340 | $2.04 | Purchase +$10,918 | 2,866,074 | No | Form 4 |
| GRCEGrace Therapeutics, Inc. | Oct 8 | Oct 13 | P | 2,077 | $2.02 | Purchase +$4,190 | 2,860,734 | No | Form 4 |
| GRCEGrace Therapeutics, Inc. | Oct 5 | Oct 5 | P | 1,694 | $2.06 | Purchase +$3,490 | 2,858,657 | No | Form 4 |
| GRCEGrace Therapeutics, Inc. | Oct 2 | Oct 5 | P | 20,000 | $2.07 | Purchase +$41,368 | 2,856,963 | No | Form 4 |
| GRCEGrace Therapeutics, Inc. | Oct 1 | Oct 5 | P | 38,796 | $2.04 | Purchase +$78,962 | 2,836,963 | No | Form 4 |
| ACOGAlpha Cognition Inc. | Oct 1 | Oct 2 | P | 19,050 | $8.69 | Purchase +$165,634 | 3,222,954 | No | Form 4 |
| GRCEGrace Therapeutics, Inc. | Sep 29 | Oct 1 | P | 7,849 | $2.09 | Purchase +$16,404 | 2,798,167 | No | Form 4 |
| GRCEGrace Therapeutics, Inc. | Sep 23 | Oct 14/A | P | 5,318 | $2.10 | Purchase +$11,168 | 2,790,318 | No | Form 4/A |
| GRCEGrace Therapeutics, Inc. | Sep 21 | Oct 14/A | P | 9,771 | $2.10 | Purchase +$20,519 | 2,785,000 | No | Form 4/A |
| ACOGAlpha Cognition Inc. | Sep 25 | Sep 28 | P | 13,426 | $8.47 | Purchase +$113,718 | 3,203,904 | No | Form 4 |
| ACOGAlpha Cognition Inc. | Sep 24 | Sep 28 | P | 18,337 | $8.57 | Purchase +$157,082 | 3,190,478 | No | Form 4 |
| ACOGAlpha Cognition Inc. | Sep 16 | Sep 16 | P | 53,029 | $8.57 | Purchase +$454,607 | 3,145,000 | No | Form 4 |
| ACOGAlpha Cognition Inc. | Sep 16 | Sep 16 | P | 27,141 | $8.40 | Purchase +$227,984 | 3,172,141 | No | Form 4 |
| ACOGAlpha Cognition Inc. | Sep 15 | Sep 16 | P | 3,375 | $8.54 | Purchase +$28,831 | 3,091,971 | No | Form 4 |
| ACOGAlpha Cognition Inc. | Sep 14 | Sep 16 | P | 40,373 | $8.70 | Purchase +$351,084 | 3,088,596 | No | Form 4 |
| SLGLSol-Gel Technologies Ltd. | Sep 11 | Sep 14 | P | 1,493 | $65.95 | Purchase +$98,456 | 540,000 | No | Form 4 |
| SLGLSol-Gel Technologies Ltd. | Sep 10 | Sep 14 | P | 1,631 | $66.80 | Purchase +$108,943 | 538,507 | No | Form 4 |
| GRCEGrace Therapeutics, Inc. | Sep 9 | Sep 10 | P | 5,836 | $2.09 | Purchase +$12,197 | 2,775,229 | No | Form 4 |
| GRCEGrace Therapeutics, Inc. | Sep 8 | Sep 10 | P | 9,393 | $2.10 | Purchase +$19,699 | 2,769,393 | No | Form 4 |
| SLGLSol-Gel Technologies Ltd. | Sep 9 | Sep 9 | P | 3,097 | $68.71 | Purchase +$212,779 | 536,876 | No | Form 4 |
| SLGLSol-Gel Technologies Ltd. | Sep 8 | Sep 9 | P | 3,390 | $68.74 | Purchase +$233,030 | 533,308 | No | Form 4 |
| SLGLSol-Gel Technologies Ltd. | Sep 8 | Sep 9 | P | 471 | $69.37 | Purchase +$32,673 | 533,779 | No | Form 4 |
| SLGLSol-Gel Technologies Ltd. | Sep 4 | Sep 9 | P | 918 | $69.52 | Purchase +$63,819 | 527,818 | No | Form 4 |
| SLGLSol-Gel Technologies Ltd. | Sep 4 | Sep 9 | P | 2,100 | $68.98 | Purchase +$144,858 | 529,918 | No | Form 4 |
| SLGLSol-Gel Technologies Ltd. | Sep 2 | Sep 3 | P | 900 | $68.95 | Purchase +$62,054 | 526,900 | No | Form 4 |
| SLGLSol-Gel Technologies Ltd. | Sep 1 | Sep 3 | P | 783 | $69.52 | Purchase +$54,434 | 526,000 | No | Form 4 |
| SLGLSol-Gel Technologies Ltd. | Aug 31 | Aug 31 | P | 5,000 | $68.24 | Purchase +$341,175 | 525,000 | No | Form 4 |
| SLGLSol-Gel Technologies Ltd. | Aug 31 | Aug 31 | P | 217 | $69.10 | Purchase +$14,995 | 525,217 | No | Form 4 |
| SLGLSol-Gel Technologies Ltd. | Aug 28 | Aug 31 | P | 10,000 | $71.40 | Purchase +$713,969 | 494,887 | No | Form 4 |
| SLGLSol-Gel Technologies Ltd. | Aug 28 | Aug 31 | P | 20,113 | $68.42 | Purchase +$1,376,137 | 515,000 | No | Form 4 |
| SLGLSol-Gel Technologies Ltd. | Aug 28 | Aug 31 | P | 5,000 | $68.81 | Purchase +$344,050 | 520,000 | No | Form 4 |
Published from this insider's public Form 4 filings on SEC EDGAR; the name is shown as filed. Named in a filing and want this page removed? See the privacy policy.